Mam what about , 5HT 4 agonist like -cisapride (not used now a days), mosapride,renzapride and tegaserod ( not used now a days because of MI and stroke)
Here is a drug with the drug mechanism that works so that it accelerates the transporter that returns serotonin back from the pre-synaptic space, what is right? A. The drug acts as an indirect antagonist B. The drug acts as a direct agonist c. The drug acts as an indirect agonist D. The drug acts as a partial agonist Plz help ?
indirect antagonist. Because it's "antagonizing" serotonin by removing it from the synapse back to the axon terminal. But it does this "indirectly" because it's not actually binding to or blocking the serotonin receptors.
Very informative presentation , but I'm surprised that you didn't mention anxiety , addiction and depression .Or maybe I missed the focus or purpose of the lecture .
Do inverse agonists cause the opposite biological cell function to be activated compared to antagonists? Or do they rather cause a more pronounced neutralization of the receptor?
basically.. an antagonist blocks the function of a receptor so no effect is exerted whereas an inverse agonist does exert an effect but the opposite effect of an agonist. So antihistamine H1 1st generation eg. Diphenhydramine inverse agonist binds to the H1 receptor but it doesn't inhibit the receptor's effect. It actually causes the opposite effect for example instead of normal effect of wakefulness in brain H1 receptor it causes sedation effect. Hope it makes sense :) As I was just revising this. Partial agonist is when it it produces agonist effect but only partially, not fully.
As far as I know MDMA is a powerful serotonin releasing agent. (It's related to Methamphetamine, however, with MDMA being the abbreviation for methylenedioxy-methamphetamine.)
Thank u I am blessed I came across your channel .....have been doing my whole pharma from here ❤
Your videos are so wholesome ma'am. Thank you so so so much🌻💕
She's awesome🎉
How both agonist and antagonist is used as drug for migraine?
Only agonist used in migrane, ergotamine is also partial agonist
4 years ago but this still works! Thank you so much!!!
Glad it helped!
MAM Triptans group are contraindicated in ICH or Ischemic Heart Disease. In this video you told Ischemic Heart disease but you wrote ICH.
No doubt great work ♥️👍
Best pharma videos i found .. thank u
Really? You might want to search CZcams again.
You don't know who speed is
@@reubenjandroh7452but I like her videos more than speed
5ht4 is not metoclopramide it's cisapride and mosapride etc
Metoclopramide is dopamine antagonist
great work. it is very helpful 👌
Mam what about , 5HT 4 agonist like -cisapride (not used now a days), mosapride,renzapride and tegaserod ( not used now a days because of MI and stroke)
Agonist; Use: Management of Irritable Bowel Syndrome with constipation.
I got this from my pharmacy notes. :)
Please correct me if i am wrong.
@@jenniemharserrana2855 can u tell me which agonist r u saying , like i want to know drug name
MY GOD GUIDE YOU AND BLESS YOU
Apne 5HT ka agonist or antagonist ka same role kasey bataya .?
Alag hoga role to.
nice video mam it is very help fully🙂
From which books u had written all these notes..plz reply
Lubz...on lecture and handwritings ...keeps going❤️😍😍
Great work
Also make some videos for 2nd year
Really good 😍😍😍
Here is a drug with the drug mechanism that works so that it accelerates the transporter that returns serotonin back from the pre-synaptic space, what is right?
A. The drug acts as an indirect antagonist
B. The drug acts as a direct agonist
c. The drug acts as an indirect agonist
D. The drug acts as a partial agonist
Plz help ?
indirect antagonist.
Because it's "antagonizing" serotonin by removing it from the synapse back to the axon terminal.
But it does this "indirectly" because it's not actually binding to or blocking the serotonin receptors.
Very informative presentation , but I'm surprised that you didn't mention anxiety , addiction and depression .Or maybe I missed the focus or purpose of the lecture .
She talked about buspirone that acts on 5HTA receptors as an anxiolytic
@@miknelltech221 Yes , she did indeed . I missed it the first time . Thanks for the correction .
Thank you so much Dear Mam!
Bhut khoob kya bat h Maja a gya.
Do inverse agonists cause the opposite biological cell function to be activated compared to antagonists? Or do they rather cause a more pronounced neutralization of the receptor?
basically.. an antagonist blocks the function of a receptor so no effect is exerted whereas an inverse agonist does exert an effect but the opposite effect of an agonist. So antihistamine H1 1st generation eg. Diphenhydramine inverse agonist binds to the H1 receptor but it doesn't inhibit the receptor's effect. It actually causes the opposite effect for example instead of normal effect of wakefulness in brain H1 receptor it causes sedation effect. Hope it makes sense :) As I was just revising this. Partial agonist is when it it produces agonist effect but only partially, not fully.
Thanks...
Very helpful
Can you use little bit larger sheet some words are not visible?!! thanks 🧬🧬
So 5ht2a has no agonist drugs?
Bwautiful video. Thanks a lot ✨
Please, can you explain why antagonist and agonist receptors have the same result with is serotonin re uptake? Thank you very much
they dont have same effects
agonist enhances uptake while antagonist blocks. However it depends on the receptor
Class 1:02
well done.. its a good lecture
Wow!..❤❤
Any serotonin releasing agents though? Only one I can really find is Methamphetamine. Releasing agents need to be made.
As far as I know MDMA is a powerful serotonin releasing agent. (It's related to Methamphetamine, however, with MDMA being the abbreviation for methylenedioxy-methamphetamine.)
Thank You
I thought 5HT 1 came in 1a and 1b?
DISTRIBUTION
5HT1a: Raphe nuclei, hippocampus
5HT1b: Substantia nigra, globus pallidus and basal ganglia
ref: Basic clinical pharmacology 13th edition page 280
Good one.keep it up.
Are you from India
No I’m from Pakistan.
@@MedMadeSiriuslyeasy tell me about tegaserod
@@MedMadeSiriuslyeasy due to difiecency of tegaserod cause ibs????
Thanku for such an video 🙏🏼
Thaaanks alot 💜💜💜💜💜💜
Thanks a lot
SAMJAYE BOHT AXHA HAI LKN Words k size thora bara rakhan tk banda ss ly kr chat k khyen aty jty phar sky ya jaldi sy revise kr sky . 😜😜👍👍
Thank you ❤️
nice
Thank you so much it was very helpful 👍👌👏
Good
AUTACOIDS not AUT(O)COIDS
Why is there a hippie in the thumbnail when she doesn't even discuss psychedelics with regards to the 5HT2A-receptor? ;)
Hint aksanı ingilizce dinleyemiyorum çok gıcık ediyor