Urea Recycling | Role of Urea in Kidney | Urea Excretion | Urea Handling by Nephrons | Renal System
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- čas přidán 23. 07. 2024
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Urea Recycling | Role of Urea in Kidney | Urea Excretion | Urea Handling by Nephrons:
From the thick ascending limb to the outer medullary collecting duct, the tubule is impermeable to urea. Now, when your body water decreases, your pituitary gland secretes antidiuretic hormone. It increases the water reabsorption, from the collecting duct. As urea is not reabsorbed from here, the water reabsorption alone, increases the urea concentration, in the lumen. So it starts getting reabsorbed at the inner medullary collecting duct. This initiates a cycle, that accumulates more and more urea, in the interstitium. This allows you to excrete urea, at higher concentrations. So the requirement for urine volume decreases. The osmolarity in the inner medulla can reach up to 1200 during this. However, urea contributes to osmolarity, only at the inner medulla. It does not contribute to osmolarity in the outer medulla, even during this. Now, when you drink enough water, the ADH level falls. Without water reabsorption, the urea does not get concentrated. So urea in the tubule is excreted in urine right away. Previously accumulated urea in the interstitium is washed out by capillaries, or, excreted in urine. During this, the osmolarity at the inner medulla falls to 600.
Chapters:
00:00 Introduction
00:21 Urea Concentration in Different Sites
00:41 Urea Recycling
03:37 Control of Urea Recycling
06:11 Importance of Urea Recycling
08:41 Corticomedullary Differentiation
09:41 Summary
11:14 Bonus Point
Dr Vipul Navadiya
Nonstop Neuron
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DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.
love you sir
i am your best students
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Great video but your voice is better than this robotic voice.
Please creatinine and uric acid