According to BRS Physiology (6th ed.), During repolarization, depolarization slowly closes the inactivation gates of Na channels. Depolarization also slowly opens K channels.
We have several questions re hyperkalemia/hypokalemia and how that impacts h and m gates; will it follow the normal pathway? Meaning, if hyperkalemia causes a depolarized state, then what do the gates do? in hypokalemia, which causes a hyperpolarized state, will the m gate close and h gate open? ps thank you so much! :)
Yeah that sounds correct. For the questions on these they'll probably focus more on the "normal" rather than "abnormal" states, however. So if you sorta know what gates are open when...that should probably be sufficient for this exam (unless they are feeling super mean haha)
Thank you for your amazing explanation sir
According to BRS Physiology (6th ed.), During repolarization, depolarization slowly closes the inactivation gates of Na channels. Depolarization also slowly opens K channels.
best video yet on youtube for this! Thank youu!
Thanks so much for this clear explanation!
Thank you
We have several questions re hyperkalemia/hypokalemia and how that impacts h and m gates; will it follow the normal pathway? Meaning, if hyperkalemia causes a depolarized state, then what do the gates do? in hypokalemia, which causes a hyperpolarized state, will the m gate close and h gate open?
ps thank you so much! :)
probably both gates open since increased AP and repeated firing, yes?
Yeah that sounds correct. For the questions on these they'll probably focus more on the "normal" rather than "abnormal" states, however. So if you sorta know what gates are open when...that should probably be sufficient for this exam (unless they are feeling super mean haha)