Acute Kidney Injury (AKI) | Etiology, Pathophysiology, Clinical Features, Diagnosis, Treatment

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  • čas přidán 1. 07. 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
    www.ninjanerd.org/lecture/acu...
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be presenting on Acute Kidney Injury (AKI). During this lecture we will be starting with a discussion on the causes of an AKI. This will include the pre-renal, intra-renal, and post-renal causes. We will then transition into the pathophysiology and most common clinical features associated in patients with an AKI. We will then conclude this lecture with the diagnosis and treatment of an AKI. We hope you enjoy this lecture and be sure to support us below!
    Table of Contents:
    0:00 Lab
    0:08 AKI Introduction
    0:29 Causes of AKI: Pre-renal, intra-renal, and post-renal
    45:30 Pathophysiology and Clinical Features of AKI
    1:20:27 Diagnosis of AKI
    1:34:46 Treatment of AKI: Pre-renal, intra-renal, and post-renal
    1:49:03 Comment, Like, SUBSCRIBE!
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    #ninjanerd #AKI #AcuteKidneyInjury

Komentáře • 416

  • @trunghieu5420
    @trunghieu5420 Před měsícem +23

    Whole chapter of AKI is explained in a video instead of a 10-hour lecture where the professors simply read from the slides. You are the best teacher ever. Thank you for your professionalism and enthusiasm !

    • @dannaca
      @dannaca Před měsícem

      INDEED!! 👏😤

  • @jaiabad1306
    @jaiabad1306 Před rokem +141

    Our college tuition should be going to these amazing people. I learn more from them than I'll ever do from all my college professors. He explains all of these concepts so well, making it SO easy for us to understand. Big thanks to you Mr. Ninja Nerd!

    • @irame5701
      @irame5701 Před 3 měsíci +1

      Totally agree. I don't know what I pay for at the college.

  • @mashhoodsiddiqui6274
    @mashhoodsiddiqui6274 Před 2 lety +147

    I had my neurology exam today and your words were literally echoing in my mind like the components of limbic system and various nuclei of hypothalamus and their functions... you person are the saviour of my grades. May God bless you. Lots of love from Pakistan!!!!

  • @yahyeabdi4774
    @yahyeabdi4774 Před rokem +8

    Why is this guy such legend that every time I look for a topic I see a one hour video of ninja nerd , exactly what I needed, u son of a gun

  • @anthonymorici
    @anthonymorici Před rokem +16

    I’m a 48 year old man just diagnosed with renal kidney failure and am deep diving in to my own journey through you! Thank you for providing intelligence and masterful communication! I am understanding what my doctors are attempting to communicate. Thank you, Anthony

  • @paulastafford1642
    @paulastafford1642 Před rokem +13

    Excellent. Thank you so much. My sister just died September 12 2022 from ATN-AKI confirmed on biopsy. Was in metabolic acidosis never showed signs of volume overload instead was dehydrated 2 days after discharge from hospital. Labs and BP were improving prior to discharge so I was told they didn't feel the need for dialysis. I still think a temporary course of dialysis may have saved her life. She had a Hgb of 8 at discharge, creatinine and BUN were only slightly elevated and K+ was 5.2. She had labs drawn the morning b4 she died and was not notified of any abn, but at the time of blood drawn was told she was dehydrated bc they had a hard time getting blood. I noticed watery loose stools in her toilet the night she died. She'd had a short run of V'tach in the hospital and chronic A-fib x 2 years. She called 911 c/o SOB and they found her face down in her apt and unresponsive. This video helped me a lot. I still believe dialysis should have been tried.

  • @HockeyGuy_in_STL
    @HockeyGuy_in_STL Před 2 lety +136

    Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently associated with AIN. I took care of a teenage girl in the ER who took ibuprofen for migraine daily for 3 weeks. After H&P and labs, I diagnosed her clinically with AIN and she was admitted to peds. Later that week, a renal biopsy was performed and confirmed AIN. So, be careful with ibuprofen!

    • @ahealingplace7350
      @ahealingplace7350 Před rokem

      Thank you, this is helpful

    • @echase416
      @echase416 Před rokem +3

      NSAIDs are serious medications. I cringe when I hear the phrase ‘take ibuprofen’ mentioned so casually… 💔

    • @shaneoneil894
      @shaneoneil894 Před rokem

      NSAIDS are poison. Jacks up everything and makes almost all chronic diseases worse. I don’t understand why it is otc .

    • @erencihan1103
      @erencihan1103 Před rokem

      NSAID These drugs disrupt renal autoregulation. Cutoffvalie60mmHg

    • @anzlaiqbalmuhammediqbal27
      @anzlaiqbalmuhammediqbal27 Před rokem +1

      What about flurbiprofen

  • @zadhi1290
    @zadhi1290 Před 2 lety +109

    Ok, Mr. Nerd Ninja I would like to say thanks. I am an IMG working as a PA in a hospital with many interns and this concept and approach to the kidney is by far the best in the game. I will be sending this to everyone I know and modifying my Step study to include your lectures in the subject that I am weak in. It is one thing to understand it in paper but your detailed info make these concept that look hard to manage easy to understand. It is safe to say that you have gone above and beyond with this AKI lecture.

  • @accountname7982
    @accountname7982 Před 2 lety +29

    I just wanna say thankyou for always explaining the basics and then covering the concept. Your channel is truly a gift to the medical community. You describe everything related to the topic, never leave even the smallest things.. that's what i love about you. Much love, keep up the good work. May your channel grow more and more.

  • @vrushitarora7760
    @vrushitarora7760 Před 2 lety +31

    Please even continue with the Microbiology series. No one explains things better than you.. need more of those.

  • @nurula1783
    @nurula1783 Před rokem +3

    man what an absolute legend. been watching for years, endlessly grateful

  • @andreafigueroa4337
    @andreafigueroa4337 Před 11 měsíci +4

    This is usually a topic that I despise studying because I struggle so much differentiating the casues of AKI, but I always come back to your videos. Thank you so much for your passion in explaining and making it easy for us to understand

  • @fghhdfg4719
    @fghhdfg4719 Před 2 lety +7

    No one can explain this topic more clearly than this
    Amazing thank you

  • @connorhill9047
    @connorhill9047 Před 2 lety +22

    I’m a nursing student who loves all of your content. I am someone who needs to know how things are connected, and you do a great job of providing clear visuals and descriptions.
    I just finished your lecture in CKD. I knew I wanted to do AKI next, and there it was in my suggested videos. The only words I have for you: thank you!

  • @abp-jk7tr
    @abp-jk7tr Před rokem +3

    This man is so good at explaining things and he is so passionate- these are the best videos!

  • @malakds400
    @malakds400 Před rokem +32

    Seeing such a hardworking person & the happiness you deliver in every course you share is priceless
    God bless you ; keep it up bro❤️ May Allah show you the right path..Ameen✨️❤️❤️

  • @mcserna650
    @mcserna650 Před rokem +1

    You are the best! Please don't stop doing this amazing job, you were born for it. As an IMG getting ready to take the USMLE you've helped me so much!!! Thank you Dr. Zach

  • @ilooovedrugs
    @ilooovedrugs Před 2 lety +4

    You're videos are amazing!! thank you for doing this. I'm a registered vet tech and am brushing up on everything and you're videos are so informative and easy to follow!

  • @kingssem1583
    @kingssem1583 Před 2 lety +5

    Incredible lecture sir 🙌🏿✊🏿,there is none on the internet better than this .thank You very much!!!!

  • @JorgeMFilho-bs8cb
    @JorgeMFilho-bs8cb Před 2 lety +3

    Ninja nerd you're a jewel in CZcams. Thanks for your excellent educational work.

  • @summermaharlika9416
    @summermaharlika9416 Před 2 lety +6

    Oh My God. I needed this lecture so much!! I have a report for AKI and this will help me a lot. Thank you so much!! I love you ninja nerd!! ❤️

  • @JoeElFrancesOficial
    @JoeElFrancesOficial Před 2 lety +4

    Incredible piece of work and beautiful summary, thank you

  • @belfiorebianco
    @belfiorebianco Před 2 lety +7

    GOAT, man such thorough detailed lessons. I never understood some complications or side effects, but the way you explain it I think I will not forget. Thank you very much to you and your team.

  • @crusader1492
    @crusader1492 Před 2 měsíci +2

    I played a drinking game while watching this video. Every time he said "all jacked up", I took a shot. I now have a hangover.

    • @hannah5552
      @hannah5552 Před 26 dny

      And hopefully you don't go into aki

  • @grohithraj2733
    @grohithraj2733 Před 2 lety +5

    Really excited for the nephrology videos!
    Thanks for all these amazing lectures ❤️

  • @sidneylopez6395
    @sidneylopez6395 Před 2 lety +3

    Thank you bro, you teach pathophys in a clear and understandable way

  • @stevehb777
    @stevehb777 Před rokem

    Long videos but full of knowledge. You KNOW this guy knows his shit because he breaks it down to the most simple level.

  • @nanadarkoampem
    @nanadarkoampem Před 7 měsíci

    I learn a lot from Ninja Nerd's lectures. His explanations are easily understood and absorbed.

  • @Kate-yi1bv
    @Kate-yi1bv Před 2 lety +3

    Unreal how great these videos are. Thank you!!

  • @irame5701
    @irame5701 Před 3 měsíci

    Love this guy: innocent and sincere in expressions and powerful with his knowledge! 👍❤️

  • @MarkBennett007
    @MarkBennett007 Před 2 lety

    As a layman…..this is over my head…… but listen and realise what a deep subject it is.
    Aiming to improve via diet…….can’t afford diagnosis and dietician based on labs.
    Wishing you all that’s good….you deserve it.
    Thank you.

  • @sAbr1na2000
    @sAbr1na2000 Před rokem

    I can't stress enough on how many times ninjanerd has saved my life !!!

  • @laurasookhai7802
    @laurasookhai7802 Před rokem +1

    Thank you so much...nursing student here, I wish professors could break it down like you do but unfortunately that's not the case, thank god for you! 🙏

  • @adfd9607
    @adfd9607 Před 2 lety +1

    Thaaaank yoooou, I've looked for it in the renal playlist it's finally here thank you

  • @sedative87
    @sedative87 Před 2 lety +3

    I really appreciate this kind of lecture. It helped me a lot

  • @selenaserane2623
    @selenaserane2623 Před rokem

    Second time i repeat that from start to finish, i don't get bored, everytime u say makes sense right! I say deep down ofc it does with a big joy, thx a lot

  • @rameezsuleman8784
    @rameezsuleman8784 Před 2 lety +2

    Very much clearly explained I am very thankful of your being a my teacher I respect you a lot thanks for sharing me this wonderful knowledge

  • @abytebit
    @abytebit Před 2 lety +3

    This is something what I've looking for... THX MAN!

  • @isabellalavagnino9640
    @isabellalavagnino9640 Před 2 lety +3

    You're something else, thank you for all the amazing videos!!

  • @marcellaryan-coker2832
    @marcellaryan-coker2832 Před 2 lety +8

    You are an amazing teacher! Thank you for doing these videos! Can you please please do a video on fluids and electrolytes pathophysiology? 🙈Some ninja nerds will be so very grateful for it😃

  • @nemonihil2952
    @nemonihil2952 Před 2 lety +2

    Thanks a lot. Extremely clear and helpful material!

  • @2006evita
    @2006evita Před rokem +1

    I am learning so much from you. You are a great teacher. You make it entertaining and exciting. Thanks a lot

  • @luciaperez1832
    @luciaperez1832 Před 2 lety +2

    As always guys, we appreciate your work a lot!

  • @ariahunonso6981
    @ariahunonso6981 Před 2 měsíci

    You are an excellent teacher! Thank you for all the work that you do 👏👏

  • @sakthipriyakurmapu9383

    Finally a video on the actual pathophys! Thank You!

  • @noumanshahzad8720
    @noumanshahzad8720 Před 2 lety +3

    I really love how you explain all the stuff ♡

  • @jeanabraham7742
    @jeanabraham7742 Před 2 lety +2

    I love the way you say," I am glad you asked" 😊..Big thanks to Ninja Nerds from NZ.

  • @maddiefreier-engle1497
    @maddiefreier-engle1497 Před 2 měsíci

    One of a kind teacher. So grateful.

  • @Rayan.F
    @Rayan.F Před rokem

    What an absolute beast. Thank you very much for these videos they are really helpful for my internal exam👍

  • @ghazalnaz7454
    @ghazalnaz7454 Před 2 lety +6

    Thank u soo much sir, urr lectures r Allah's gift for me, my exams r coming ahead, nd im piled up with medicine, surgery, paeds gynae obs😑 and ur lectures specially this medicine series is really helping me out, keep the good work 😇

  • @amineahsengeldi3071
    @amineahsengeldi3071 Před 4 měsíci

    Thank you so much that finally I understand this subject. Thank you and to your team for your passion and effort :))

  • @rayyaalghazali5349
    @rayyaalghazali5349 Před 2 lety +1

    Thank you from the bottom of my heart

  • @NickinNashville
    @NickinNashville Před 2 lety +7

    omgosh im so stoked on these videos. You are truly a gifted teacher. I work at University and this blows other classes out of the water, even using the phrase "peeing outta your butt"....

  • @hibakamran3554
    @hibakamran3554 Před 2 lety +1

    That's so gripping 👌🤗thanks Dr. Zach

  • @rudolfdiesel7.3version31

    Wow! I am not a medical student and I can follow along. Thanks so much, helped on this end.

  • @ashm003
    @ashm003 Před 2 lety +4

    Thank you for another great lecture!

  • @trlanhuseyn741
    @trlanhuseyn741 Před 2 lety +31

    Zack, please make lectures about Histology. Appreciate it beforehand.

  • @frankmaggio4328
    @frankmaggio4328 Před 2 lety +6

    Thank you for making this video. As an ER Nurse we see, we treat, we either d/c or admit. We leave it up the NP,PA,MD to figure out what's going on with the patient. After a while you start to ask deeper questions as to why this was ordered and why that was ordered. Thanks for explaining AKI. Now I know why the U/S are ordered after the chemistry and u/a comes back. Now everything is CT scans but I always wondered why the U/S order but was too busy to ask.

  • @DrsundasMD
    @DrsundasMD Před 8 měsíci

    N i bet no person could work more harder than prof zach Murphy ❤

  • @compilation8104
    @compilation8104 Před 8 měsíci

    how i regret that i didnt find u earlier still im so grateful. hope to comeback after acing my exam to thank u

  • @MrKhannasahil
    @MrKhannasahil Před 2 lety +1

    Thanks for the acceptance of topic suggestion of arf and causes 👍🙏

  • @monishshivamonishshiva5392

    Mesmerized 😊, Amazing 🙏🏻, this class very much useful ...

  • @mariama.sgodhelpme2264
    @mariama.sgodhelpme2264 Před 11 měsíci

    After getting disappointed from nephrology , here I am to strat again all is due to this great explanation , In whole my life I didn't find someone explaining like this , God bless you sir , all love to you , respect and good luck always your easy detailed words still in my brain , i can't forget ❤❤

  • @ceciliacheptoo4945
    @ceciliacheptoo4945 Před 2 lety

    Ua videos are exhaustive and soo helpful..i search for your videos in every topic of internal medicine I read...thanks🤗🤗

  • @BunleangKors
    @BunleangKors Před rokem

    I like to learn from your teaching so much. Thank you for your knowledge's sharing.

  • @ObnoxiousOtter8
    @ObnoxiousOtter8 Před rokem

    I will now forever associate AKI not by the aetiology of the reduced eGFR - no, never again - but a by new criteria for a new age: whether tubular cells are all jacked up or not.
    We love you, Ninja Nerd Team. Thank you from the bottom of our hearts, may God bless you.

  • @tamipock3578
    @tamipock3578 Před 2 lety +3

    Thank you for all the videos. I would love to see you do a video about pulmonary hypertension. I have this due to a congenital heart defect.

  • @shaneoneil894
    @shaneoneil894 Před rokem +28

    I pay thousands a year in school fees and I get more value from your CZcams lectures. Thank you. I’ve gotten a bunch of As due to your efforts.

  • @mohammedjama8067
    @mohammedjama8067 Před 2 lety +2

    Thank you very much from Ethiopia, really i love your teaching techniques, and thanks.

  • @nadasalah4343
    @nadasalah4343 Před měsícem

    From Egypt thank you so much for this amazing lecture

  • @joseibarra4485
    @joseibarra4485 Před rokem +1

    Thank you for your lectures! Life saver!

  • @karengallie9783
    @karengallie9783 Před 3 měsíci

    These lectures are so good. I have learnt so much thank you. 🎉

  • @humbertohenriquez1722
    @humbertohenriquez1722 Před 2 lety

    Thank you for making things clear for dummies

  • @Argos534
    @Argos534 Před 2 lety

    Greetings from mexico this is one of the best yt medical channel i’ve ever seen,,

  • @chrystalselous1511
    @chrystalselous1511 Před 8 měsíci

    I love this video, so clearly explained, thanks Dr

  • @lindsaybarnard6627
    @lindsaybarnard6627 Před 7 měsíci +1

    Both YOU and the kidneys are equally amazing!!

  • @eduardat3449
    @eduardat3449 Před 2 lety +1

    Thank you, you are saving me!

  • @bozo4188
    @bozo4188 Před rokem

    Omg i really need your energy and your brain for my exams

  • @MeddymaticsDrSwatiPandey
    @MeddymaticsDrSwatiPandey Před 8 měsíci

    I love the way you explain things so easily.....❤️ Keep it up... spread knowledge

  • @ivanakurdi6139
    @ivanakurdi6139 Před rokem +2

    As always you are the hero man❤ and you’re always saving our life😢❤

  • @abdihome9847
    @abdihome9847 Před rokem

    Thank u very much u make our life simple by ur detailed explanation....

  • @miamia389
    @miamia389 Před 3 měsíci

    Very helpful thank you I wish to see more of ur videos

  • @surreyhub7108
    @surreyhub7108 Před 2 lety +1

    Wow thank you that was so informative you are very talented and know your stuff.

  • @miraq3261
    @miraq3261 Před 9 měsíci

    شنو هالابداع رهيب وربي 🔥🔥🔥

  • @may_mohammad
    @may_mohammad Před rokem +1

    شكرا لكم على هذا الإتْقان

  • @mutharasanperiyappayan8063

    what a knowledge this great doctor has!absolutely stunning .It is something like a human robot

  • @nuttyhill3218
    @nuttyhill3218 Před rokem

    You made me love this topic💚thank you

  • @squirrel5811
    @squirrel5811 Před 2 lety +2

    Blue clues for medical lectures. This stuff is amazing.

  • @mohamedsoliman906
    @mohamedsoliman906 Před 2 lety +1

    Amazing
    Thank you so much for this great video

  • @longjohn2726
    @longjohn2726 Před rokem +1

    Amazing you helped me a lot. You are the best!!!!

  • @giovannotecconecco6269
    @giovannotecconecco6269 Před 2 lety +4

    content is awesome, just a little note, at around min. 7.46 when he describes nephrotic syndrome he is describing characteristics of nephritic syndrome (hematuria, hypertension and lipiduria)

  • @anweedebta7781
    @anweedebta7781 Před 2 lety +2

    Thank you so much.. 🙂🙂 Finally understood physiology 🙃

  • @987zyx
    @987zyx Před 24 dny

    Thanks, just another great video

  • @violetterobinson6542
    @violetterobinson6542 Před rokem +2

    Dude this video is the bomb. I’m going to ace my nursing exam!

  • @snehalkumarpatil8264
    @snehalkumarpatil8264 Před rokem +1

    Great sir....nice... outstanding...I have no words to explain your talent and the way you are present,it's really awesome ...keep it up sir

  • @sanaamani3189
    @sanaamani3189 Před 11 měsíci

    Thank you thank you thank ,you ,your videos are amazing, and help me a lot in internship, thank you ❤❤❤❤

  • @raghavparanjape1551
    @raghavparanjape1551 Před 2 lety +2

    Zach sir I'd just like to request that it would be cooler if you could divide one huge video into two or three parts, like your previous older content, so that it becomes easier for us. Otherwise, i just love you and ninjanerd!!

  • @vaqasyousef6229
    @vaqasyousef6229 Před 2 lety

    I am very thankful too you such a best concept is given love you soo much

  • @ikon2880
    @ikon2880 Před 2 lety +1

    You are amazing!!! Thank you so much!!!

  • @hannateodrosgirmatsion9155

    I can't stop watching your videos even I am level one nursing student thanks!