Tablet Coating

Tablet Coating
Tablet is a pharmaceutical dosage form. It comprises a mixture of active substances and excipients, usually in powder form, compressed or compacted into a solid. Tablets Dosage form is one of a most preferred dosage form all over the world. Coating is a process by which an essentially dry, outer layer of coating material is applied to the surface of a dosage form in order to confer specific benefits that broadly ranges from facilitating product identification to modifying drug release from the dosage form. Tablet coating is the application of coating composition to moving bed of tablets with concurrent use of heated air to facilitate evaporation of solvent.
Tablet coating is the key step involved in the manufacturing of tablets having controlled release, delayed release profiles. The tablet coating have number of advantages like masking odor, taste, color of the drug, providing physical and chemical protection to drug, Protecting drug from the gastric environment. 3 primary components of tablet coating are tablet properties, coating process and coating composition. Tablets are usually coated in horizontal rotating pan with coating solution is either directly poured or sprayed on to them. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form. Recent trends in tablet coating focuses on overcoming disadvantage of solvent based coating. This article concerns with the coating process, equipments involved, coated tablets evaluation and specialized coating techniques.
• Contents
• Need for tablet coating, types of coating, tablet core properties.
• Sugar coating - Raw materials, Steps in detail, Sugar coating defects/problems.
• Film coating including Enteric coating.
• Raw materials, Aqueous film coating, film coating defects/problems.
• Coating Equipments - Conventional & modified pans, coating columns (fluidized bed coating), Spray equipment & other accessories..
• Quality control of coated tablets
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