Myricetin

Title: ​Myricetin
Peer Reviewers: ​Sydney Santos
Introduction:
Myricetin is a naturally occurring flavonoid that can either be extracted from Southern Wax Myrtle, or it can be consumed in diet through a variety of foods such as red wine, berries, vegetables, and tea (Ristic, 2020). It is known for its antioxidant, anticancer, and anti-inflammatory properties. Currently, many research studies are looking into how Myricetin can help treat or slow the progression of Parkinson’s Disease, Alzheimer’s, and Dementia by reducing the cognitive decline associated with these diseases. One recent study looked into how Myricetin was able to improve the brain symptoms of Traumatic Brain Injury (TBI), such as cognitive disabilities, in rats that were induced with TBIs (Mirshekar et al., 2019). As well as being known for its ability to reduce oxidative stress induced damage on the central nervous system, Myricetin is also being researched for its potential antitumor properties, which may include modifying cancer hallmarks such as cell proliferation, apoptosis, and signaling pathways (Devi et al., 2015).
Future Research Opportunities:
● Antitumor properties
● Molecular mechanisms behind how it improves cognitive deficits
● More clinical trials to observe its long-term effectiveness in humans
● Study its neuroprotective properties
References:
Agarwal P., Bennett, D. A., Booth, S. L., Holland, T. M., Leurgans, S. E., Morris, M. C., & Wang, Y. (2020). Dietary flavonols and risk of Alzheimer dementia [Abstract]. Neurology, 94(16), 1749-1756. doi:10.1212/wnl.0000000000008981
Ara, G., Afzal, M., Jyoti, S., Naz, F., Rahul, & Siddique, Y. H. (2019). Effect of Myricetin on the Loss of Dopaminergic Neurons in the Transgenic Drosophila Model of Parkinson’s Disease [Abstract]. Current Drug Therapy,​ ​14​(1), 58-64. doi:10.2174/1574885513666180529114546
Hara, Y. (2020, April 22). Can flavonols prevent Alzheimer's disease? Retrieved August 13, 2020, from
www.alzdiscovery.org/cognitiv...
Mirshekar, M. A., Najafi, R., & Shabani, S, & Shahraki, M. (2019). The ameliorative effects of myricetin on neurobehavioral activity, electrophysiology, and biochemical changes in an animal model of traumatic brain injury [Abstract]. Learning and Motivation, 68, 101597. doi:10.1016/j.lmot.2019.101597
Myricetin 97.0+%, TCI AmericaTM [Digital image]. (n.d.). Retrieved August 12, 2020, from
www.fishersci.com/shop/produc...
Ristic, A. (2020, January 03). Potential Myricetin Benefits + Sources & Side Effects. Retrieved June 22, 2020, from ​selfhacked.com/blog/myricetin...
SOURCE NATURALS Myricetin 100 Mg Tablet, 60 Count [Digital image]. (n.d.). Retrieved September
21, 2020, from
www.amazon.com/SOURCE-NATURAL...
UF/IFAS Solutions. (n.d.). Waxmyrtle [Digital image]. Retrieved September 21, 2020, from nwdistrict.ifas.ufl.edu/hort/...

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What’s the biggest difference between Myricetin vs DihydroMyricetin?

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Salom yahshimisiz mirisetin kayerdan topsa boladi