How does St. John's Wort Interact with Drugs? Q and A with Dr. Gurley

In this video clip, Dr. Bill Gurley discusses how St. Johns wort reduces the effectiveness of many medications.
To learn more about interactions between supplements and drugs, watch Dr. Gurley's lecture "Clinically Relevant Herb-Drug Interactions: Past, Present, and Future" at nccih.nih.gov/training/videol....
Free CME and CE are available.
Bill J. Gurley, Ph.D., is a professor in the Department of Pharmaceutical Sciences and director of the Clinical Pharmacokinetics Laboratory at the University of Arkansas for Medical Sciences College of Pharmacy.

[@lisamainier4172]

Does this occur at all doses of St. John's Wort? Does this occur only at high doses or the common doses?

[@NIH_NCCIH]

+Lisa Mainier Thanks for your question. Common doses of St. John's Wort can produce serious interactions. There are many documented cases of pregnancy, organ transplant rejection, and other serious problems that are associated with the herb interacting with prescription medications.
You might find this section of Dr. Gurley's lecture informative, since he discusses several case studies: nccih.nih.gov/training/videolectures/14/6

[@SathishKumar-mn1zw]

Dr looks like Shawn Michaels 😆😆