Ionizable lipids to optimize RNA-LNP delivery - Cytiva

Lipid nanoparticles (LNPs) mediate targeted, safe, and efficient intracellular drug delivery across applications and modalities including vaccines, cell therapies, protein replacement, and gene editing.
Ionizable lipids are the most important excipient as they play a significant role in protecting nucleic acids and facilitating their cytosolic transport.
A well-characterized ionizable lipid portfolio can be leveraged to optimize delivery potency, biodistribution, and the LNP pharmacokinetic profile, enabling rationally-designed, scalable formulations that maximize performance.
Learn more about ionizable lipids and lipid nanoparticles at www.cytiva.com