Introduction to Cancer Biology (Part 1): Abnormal Signal Transduction
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- čas přidán 25. 10. 2012
- This animation is the first part of the series "An Introduction to Cancer Biology", and explains the mechanism of abnormal signal transduction resulting in uncontrolled cell proliferation. This animation also provides an overview of the potential targets of anticancer therapies.
REFERENCES:
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7. Batra SK, Castelino-Prabhu S, Wikstrand CJ, et al. Epidermal growth factor ligand-independent, unregulated, cell-transforming potential of a naturally occurring human mutant EGFRvIII gene. Cell Growth Differ. 1995 Oct;6(10):1251-9.
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Ah yes of course, I understood everything.
*rewinding intensifies*
This was just a great video !!! thanks for editing, producing and thanks for people on sharing!
this is just EPIC and extremely awesome , i really can`t tell how i loved that series . excellent work INDEED
pretty dope series about the cancer mechanism! trully enjoyed it.
Amazing high quality video!!! Thanks so very much for creating it!
Very good video. It demonstrates how many moving parts are involved in cancer and why most drugs fail to control it. We just do not know enough of the incredible complexity involved in cancer development
I found this video extremely helpful, it has provided a basis about signaling within a cell.
I would recommend this video to someone wanting to brush up on intracellular signaling.
Excellent video! Now THIS is a good way to learn. Keep up the good work :)
Thanks a lot! Excellent video!
extremely instructive...thank you
ultimate and outstanding video.
Thank you for this amazing and very pratical vidéo.
Awesome explanation :-)
Very good explanation
Great video
Thank you for a great video
Yes Yes Yes Sir💖💖💖 GooooooD 💚💚
super nice video!!
Thanks! uploader
great !!!
superv explaination :)
thank you so much
Very good! I was able to learn more
very very very well explanation
thank you
Nice video, it explains how the body can heal itself if we give them good balanced nutrition.
Where can I find transduction pathways associated directly with gene expression and regulation?
Fabulous
great vid
thank u soo much.......
Great!
thank u
Great.
nice one
awsome
Transforming Growth Factor Alpha, Not Tumor Growth Factor Alpha. Tumor Growth Factor Beta, Transforming Growth Factor Alpha.
Can someone please suggest some good introduction textbooks about general cancer biology?
The animation is excellent and the explanation are clear but very unstructured. It was hard to take notes while watching
Interesting
The animation is way too good.
Introduction to Cancer Biology (Part 1): Abnormal Signal Transduction
I hope someone finds a cure some day
+Yessi Perez ... or at least a way to tame and regulate cancers. Sometimes a mass of fast-replicating cells can come in handy, but we would still need a way to tell them when and where to stop or slow down, and tell them not to metastasize.
Trinitrophenylnitramine just stop eating anything
umm --the video says that overexpression of Growth factor receptors causes ligand independent firing - id look over that one more time
Its more likely structural mutations to the tyrosine kinase receptor cause ligand-independant activation while overexpression, on the other hand, causes hyper proliferation in basal levels of growth factor
When the receptors are over expressed, the Monomers of receptor tyrosin kinases will interact with each other due to the abundance of the receptors on the plasma membrane.
Thus, the overexpression of the receptor will lead to the activation of these receptors by each other by means of transphosphorylation(biochemically speaking-biologically speaking autophosphorylation), giving the cell an oncogenic power.making the cell mitotically active irresepective of the ligand presence. (ligand independent firing).
Seems to me like a promotional video of how well they are doing. Which is fine even if it's not true. But not fine if, "not true", holds up some other research which is.
can anyone let me know, what does he say in the 50th minutes? solid .... molecules,
thank you
"...extracellular matrix components, or cell adhesion molecules."
trying to wait until they mention mitochandia....when????
nice
Because they hav seen better ones..which are much more clear..
Cell antenna
When your lecturer is useless... go to youtube >,
Want arabic translation please
Solution :
*Dr Otto Heinrich Warburg* German MD physiologist and biochemist, Nobel Prize for Physiology or Medicine in 1931:
*>*
Very good explanation
thank you
thank u