Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency, “aka favism”
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- čas přidán 30. 01. 2018
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G6PD deficiency (favism) is an x-linked recessive disorder, therefore more common in males than females.
G6PD deficiency is protective against Plasmodium falciparum malaria.
Patients may experience an acute hemolytic episode after consuming fava beans (that's why it's called "favism"). Fave beans, in this case, is an oxidative agent.
Symptoms include jaundice (yellow skin, dark urine), fatigue, pallor, drowsiness, exercise intolerance, shortness of breath, abdominal, or lumbar pain.
The most common stressor in G6PD deficiency is infections.
Reticulocyte count will be high in this case
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Does dark urine present in haemolytic conditions,bcz dark urine is shown when,the conjugated bilirubin passing through urine in obstructive jaundice.
In haemolytic anaemia ,no bilirubin is passed in the urine ,except only the light colouring urobilin is only expelled in the urine,so chances of dark color in urine is less.
0:00 G6PD
6:47 Favism
8:16 Importance of G6PD 3 Functions of NADPH
9:52 Pathophysiology
11:59 Clinical Manifestation
13:50 Oxidative Stressors
16:13 Diagnosis
20:29 Management
Thanks you❤️
كنت عطول مستغربة كيف أجنبي بيتمسخر بنص الجد وبيشرح بهضامة وبس عرفت أنك مصري ارتاح بالي 😂، بس الجد شرح أروع من رائع 👏🏻
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هو جد مصري ؟
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Iam proud an Egyptian guy has a channel like this with this super great effort .
شكرا يسطا وبالتوفيق دايما 😁😆
الجمدان ده ميطلعش غير من واحد مصرى فعلا
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I knew this sarcasm had an Arabic tint 😂
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Thank you so much man, great explanation
BTW Didn't know you were Egyptian. Your English is pretty good :P
Greetings from an Iraqi student who studies in Cairo
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honestly MORE THAN INCREDIBLE !!! keep going we really need you guy
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thank you very much for your precious hematology series , you can't imagine how much these videos were helpful for me ...go ahead
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الله الله ام الدنيا تنجب من افضل القنوات لتعليم الطب، احلى خبر والله!
This was very good. Learned way more here than any doctor I have been to. Most are clueless and only tell me to just avoid fava beans and that’s it. Thanks so much for sharing this. 😊
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The most detailed information that I have ever seen on g6pd deficiency!
Thank you!
Very well put together explanation. I love how you explain other small things that relate to the topic, a bunch of things that I forgot.
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why this deficiency only affect rbcs not other cells?
Really useful for my GP AKT exam - thanks! Didn't realise you were a student when you did these videos, thanks for teaching us doctors what to do, haha.
أنا قرأت التعليقات وعرفت إنك مصرى فرحت جدا والله مكنتش مصدق أنا فى طب المنصورة وعمرى ما جربت شرح اجنبى بس سمعتك بالصدفه واستغربت إنى فهمت عشان كده قرأت التعليقات 😂😂❤️❤️❤️❤️
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Amazing videos always! Great enthusiasm, knowledge and humour :) Thank you for helping me though the final year of my degree !
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This is very simple and informative as well. I've been watching lot's of videos and this is the best channel till now!. Best of luck
I'm really proud to know that you're Egyptian
" another Egyptian student :D "
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you are a wonderful patho physiology and biochem pathway teacher: you stick to the point, explain si,ply and are interesting to listen to. I hope you become a professor.
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والله انك فخر العرب 🇪🇬🇸🇦❤️
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هو عربي؟؟؟
Yes
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Thank you for your amazing presentation
You helped me in my presentation on g6pd more than any video i have watched ❤
So proud and happy to see a fellow Arab succeeding in life and also helping others. Thank u u have helped in many courses wish u all the best and happiness.
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Straight to the point! Excellent explanation,thank you!!
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فخر لمصر ى دكتور والله ❤🎉
رائع 👏👏👏
اتمنى فى يوم انى اكون بهذ المستوى الراقى ، طالبة طب مصرية
Excellent. It's my first time to think that studying is funny
Keep going
Yeah! It can be funny 😁
A very interesting and a well explained Video, thank you very much for the pathophysiology details, keep up the good work.
My pleasure 😇
Thank you so much
Hello @medicosis perfectionalis I read the opposite for G6PD-deficiency on Uptodate they wrote: "The net effect is that the deficient red cells become rigid and nondeformable, making them susceptible to stagnation and destruction by reticuloendothelial macrophages in the marrow, spleen and liver [45,46]. Although this type of hemolysis is predominantly extravascular, intravascular hemolysis also occurs, leading to hemoglobinemia and hemoglobinuria." I read in alot of sources that it is predominantly intravascular like you mentioned, but I'm no longer sure.
Thank you for your incredible videos!
ماشاء الله بجد متوقعتش انك عربي مش مصري حتى انا قولت ده دكتور اجنبي وحبيت الطريقة جدا جدا
شكرا جدا لمجهودك الرائع
Keep going 💙
Greets from Egypt , we are proud of you ♥♥
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ما شاء الله رائع , شرح جميل و لفظ متقن للغة الإنكليزية . من فلسطين شكرا مصر.
😊👍👍
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اقسم بالله انت برنس عااااش
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The best explanation I 've ever seen ,thanks from KSA.
Glad it was helpful!
“Oky doky” how i knew you’re steins gate’s fans 🤣♥️thank you
Living with a g6pd deficiency- information is hard to come by. This helped me understand so much more than any dr has ever taken the time to do; especially for a common deficiency. Although I don’t eat a lot of beans and avoided them my whole life; I was exposed to fava beans/falafel possibly due to the restaurant using the same oil or tools to fry the French fries as they do the falafel. I had a painful reaction afterward. It felt like the RBC’s were trying to escape through my skin or by any means possible. & now I understand why the urine is so dark afterward. Thank you for this.
Thank you 🙏
I wish you all the best!
Doctor you are so fuuny and i am an egytian medical student so proud of you . glad that you are an egyptian too❤❤❤❤
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All due love and respect brother ❤❤❤
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I am not a genius!
@@MedicosisPerfectionalis man enough humbleness you’re a legend…
May Allah bless you and give you happiness 🤍❤️💖
ابداع كالعادة
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Very nice thanx M medical student from Iraq and the way that U use it for explain thnings its really amazing
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فخر العرب 🇪🇬 Thank you very much for your work, you're a life saver
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Greetings 😁😁😁 ...Welcome aboard!
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ممتاز
و الله انت اللي فخر مصر و العرب .. :D
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vous etes le meilleur Dr 😀
To be honest Our University (HAWLER MEDICAL UNIVERSITY COLLEGE OF MEDICINE) Must reward you for Sharing these Unique and Useful videos 💯
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Thanks sir for making me this good videos to clear my mind
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YOUR VIDEOS ARE CLUTCH
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what a great lecture, thank you too much from Palestine
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Greeting from alexandria 💖 you are a great teacher actually 💓
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Thank you so much for your medical videos! You explain everything so well, and I love your humor. I am a 58 year-old woman and work as a medical laboratory scientist in a hematology and chemistry lab. I am studying to get a hematology specialist certification, and I listen to your videos during my long commute to and from work. When I get home, I go over the slides. You have helped me so tremendously! Thanks again!
At what levels are dangerous my hemoglobin levels are 10.7
What a great lecture.. tbh i just needed around 10min of the video but ended up watching it whole, i wish u were in place of my boring, robotic lecturer
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Well explained thank you!
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Very informative lecture pls elaborate more for g6pd drugs which can be safely given.
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تحيا مصر ياعم
فخور بيك والله
Ur presentation is on point😂👍 thoroughly enjoyed and understood the class
Thank you so much ☺️
@@MedicosisPerfectionalis also your talking to A 10 year old with G6PD
You’re a medical student!! I thought you’re a professor
Hi, thank you for the video, can you please tell me what other food that g6pd should avoid, thank you 🙏
excellent lecture
Thank you so much! I’ve really worked hard on this one :)
شرحك رائع ما شاء الله
الله يزيدك من فضله
🙏
Amazing and educative. Easy to understand and to remember. Thanks so much. You have no idea what great blessing you are to me and others who have been denied so in-depth explanation to the whats and whys of g6pd. Thanks so much. God bless you.
Thank you so much 💜💜💜
Thank you!
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Man, you are great ♥ ♥ and now I'm carving to Flafel hahah !!!
Greetings from jordan
Haha 😂
Thank you so much, brother!
gREAT.... watching u from Lovely Egypt
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Dude I didn't know u r Egyptian, I'm Egyptian too, you helped me a lot thnx.
My pleasure 😇
thank you this is perfect
You're welcome!
Very very good explained.
I do have infections. Lyme, Bartonella and Babesia and also G6PD-Deficiency.
What would you recommend to fight these infections.
As we saw in the video antibiotics will make it worst.
It’s an option to substitute nadh and Gluthation?
Please give me some help.
By the way: I am from Germany and my mother is from cairo
واو حضرتك مصري ❤️
دا شيء فوق العظمة يعني وكون المجهود يطلع بالصورة الرائعة دي فدا شيء عظيم جدا ، كنت هكتب بالانجليزي بس لما لقيت حضرتك مصري فقلت اكتب بالعربي . 😂
ربنا يبارك لحضرتك كتير
والمصريين وطلبه الطب خصوصا هنا بيدعوا كتير لحضرتك .
😃😃😃😃😃😃😃😃
I proud your Egyptian as me bro♥️go on your good work
Thanks 😊
Thank you so much
You're most welcome 🙏
Ommmgggg… why Egyptian dr always amazing in make u understand everything!!!
Thank you 🙏
Thank you very much👍🏻
My pleasure 😇
I HAVE SCD TRAIT AND G6PD DEFICIENT BASED ON A HEMOGLOBIN ELECTROPHORESIS. MOM HAD SCD AND BETA THALASSEMIA. SHE RECENTLY PASSED AWAY AT 78 YOA DUE TO ACUTE LIVER FAILURE! SHE WAS IN STAGE 2 KIDNEY FAILURE AS WELL! I DO MODERATE FROM CHRONE’S DISEASE AND A LOT OF STOMACH ISSUES!
You are egyption🥺 please till me what to do to travel i am stuck here with internal medicine exams and your blood tutorial are very useful thanks❤️❤️ شكرا جدا
Excellent!
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Amazing! Thanks
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You are love...you are the best♥️
Your English is superb.
Thank you!
Rasburicase used only experimentally for gout; used commonly for tumor lysis syndrome.
I suffer from lyonization, have Mediterranean varient. Have gone into hemolytic anemia many times.
What should I look out for?? My sons been acting really sleepy.
You're Egyptian?? Wow, thanks from a fellow Egyptian, you make everything easier, lots of love❤
Thank you!
thank you! you made it easeier to uderstnd
My pleasure 😇
بتابعك من فترة و بحب طريقتك فالشرح و بحاول اكون كرييتف زيك في أي presentation في الكلية ❤️
And try to explain it easy like you,
Iam top fan for your channel, So proud of you and egyptians doctors 🤩❤️🇪🇬
فخر العرب الحقيقي 🥳🥳❤️🇪🇬🇪🇬
Thank you so much 😊
You are making us all proud Egyptians ❤❤
Thank you!
hi sir i am nursing student but i have greatly understand this lacture 💪💪👍👍😊😊
Awesome 👏