Parkinson's Disease- Dr Matthew Phillips: Fasting & Dietary Strategies as Parkinson's Therapies
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- čas přidán 7. 02. 2023
- Watch this excellent presentation with a very good Q&A at the end, of Dr. Matthew Phillips exploring the potential therapeutic benefits of metabolic strategies, particularly fasting and ketogenic diets, in neurological disorders.
Matt is a clinical and research neurologist at Waikato Hospital, Hamilton, New Zealand. His foremost passion is to explore the potential feasibility, safety, and efficacy of metabolic strategies, particularly fasting and ketogenic diets, in creating alternate metabolic states that may benefit people with a variety of neurological disorders. His team conducted the world’s first randomized studies involving only people with Parkinson’s, followed by Alzheimer’s. He is currently conducting a clinical trial involving that combines intensive fasting with a ketogenic diet alongside standard treatments in patients with glioblastoma multiforme.
Further resources:-
Metabolic Strategies in Healthcare paper
www.ncbi.nlm.nih.gov/pmc/arti...
Parkinson's RCT
movementdisorders.onlinelibra...
Metabolic Plan (click Resources)
www.metabolicneurologist.com/
Fasting to generate Brain Health, with Dr. David Perlmutter • Fasting to Benefit Bra...
• Dr Matthew Phillips - ...
You can follow Matt on Twitter / drmclphillips
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Mark my words. Our medical community is gonna thank Dr Matthew phillips for his contribution. He is considering out of the box possibilities.
My thanks Adil! I guess we will see. Regards, Matt.
I am not sure I agree. Our medical community will go through an upheaval first. They will need to re-assert their titles as doctors and teachers to healers.
@@drmclphillips I am hoping that folks suffering from this condition are reaching out to you in droves to learn and perhaps manage their personal situation more specifically -- inc folks like Billy Connelly, Michael J Fox etc.
Very interesting study.Thank you.
@@drmclphillipswhat about B1 and Mucuna I’m 39 and I just got diagnosed I’m thinking I’m taking those instead of carvidopa/levadopa I’d appreciate your response a lot
I have PD and have been on a ketogenic food program for over one year...symptoms are stabilized...I'm convinced keto has many effects on viruses and cancer too...
Do you take medication?
I believe Dr Sayfried has shown that mitochondria malfunction makes cancer a metabolic disorder. Cancer does not use oxygen to make atp but uses the fermenting attribute to generate energy and thus to starve it to death without glucose is a completely new method to deal with cancer. So yes fasting will work with cancer. Your own victorious cells will remove this horror.
I am 75 years old and i am a long time runner and weight lifter although not with the endurance and intensity as in my younger days. Intuitively, i understand your work and I do intermittent fasting myself. My fasting can be two days or three days. I have cut my 25 Carbidopa/ 100 Levodopa from 8 tables to just three tablets a day spaced 5 hours apart. I agree with your assessment, based on my own experience with my particular Parkinson’s, the non-motor symptoms are my bane in this affliction.
Incidentally, my Parkinson’s may have been brought about by Vietnam exposure three direct sprays with Agent Orange. Moreover, I worked in cotton fields that eventually were sprayed with pesticides and herbicides. Additionally, i did a little boxing in my youth and quit after being knocked down three times in one round. I could not continue after the multiple blows to my head. According to my genetic testing, I do not have a genetic propensity for Parkinson’s.
Thank you, I enjoyed this lecture.
Good for you!! Thank you for sharing. How long did it take for you to reduce your meds, and how did you know it was a good time to reduce it? Keep shining❤
I wish I could have helped my grandfather. He, and all his brothers, succumbed to Parkinsons. They grew up on a farm, exposed to many chemicals I'm sure. As a kid I heard about L-dopa and that it didn't help my grandpa too much. Because of the low fat craze at the time, my family thought too much butter contributed to his disease! There is so much more information now. Yes, I so wish ...
Grateful I came across this presentation and Q&A ...thank you for posting this! I've just been diagnosed with PD (mild motor symptoms so far), and after reviewing this and several other of Dr. Phillips presentations, I'm determined that before I go on any meds, I want to turn my system around with fasting and keto.
Thank you very much Craig. Please also have a look at the B Bloem presentation on Exercise. Combining nutrition and exercise is the key to managing symptoms and hopefully slowing down progression.
@@nosilverbullet4pd998 I will do that!! Thank you. Fortunately I'm already very active with tennis, hiking and weight lifting.
@@nosilverbullet4pd998 I thought the B1 therapy session was really good as well. Grateful that you are providing so much information to the community.
@@craigcooper9967 thank you
Were you able to go on a keto diet for the last few months? Have you seen a difference?
Is Dr Phillips aware of the work of Prof Terry Wahls of the University of Iowa Medical School? She devised a dietary protocol for Multiple Sclerosis patients (including herself) called the Wahls Protocol. It is a Keto diet. Her first book on the subject is called Minding My Mitochondria !
I will definitely mention it to him !
Hello! Yes indeed, I sure am - I often recommened the Wahls protocol for our multiple sclerosis patients. Sincerely, Matt.
Thank you, Dr. Phillips, for this phenomenal presentation! It confirms what I've been thinking about the benefits of fasting for PD since I learned about fasting last year. You explained everything so clearly and eloquently. I've done a lot of Googling and never come across your work before, so I'm so glad that someone in a Parkinson's Facebook group posted a link to this video! I'm so excited that you're doing this work with Parkinson's patients, and I REALLY hope you're able to do a longer study that incorporates fasting!
You mention mitophagy in your presentation. I originally became interested in fasting because of autophagy. I first thought that fasting could benefit PD because autophagy could eliminate the Lewy bodies. But upon reading the book Brain Fables, I learned (as you mention in this video) that Lewy bodies are likely not the cause of PD. At the very end of Brain Fables, they mention research being done by Dr. Kariem Ezzat at the Karolinska Institute in Stockholm. The research is on the invisible nanoparticles or viruses (what they refer to as “nucleating factors”) that trigger normal proteins to change shape, become insoluble, and lose function. This made me think about how autophagy could allow the body to get rid of any toxins, viruses, etc that could be triggering PD. So, maybe this is another way (in addition to mitophagy) in which autophagy can help to heal PD.
I fear we'll see a boom in “autophagy activator drugs” that induce autophagy. I can't imagine they'll be as effective as what our body knows how to do on its own. I truly hope that the majority of people choose the more natural route. Our bodies know how to heal - we just need to give them the chance!
Thank you again for the incredibly important work you're doing!!!
Excellent! Thanks from Bangladesh ❤
Dr Phillips you’re an angel- your work, outstanding efforts and perseverance is life changing to many sufferers of these conditions and helps us understand them better..
Incredibly educational presentation - God bless you both 🙏🏻
Truly humbled by this comment. I will just keep focusing on the work in people with PD and other disorders, there's much to do. Thank you so much - Matt.
Brilliant person..because..he shares his wisdom and knowledge..grateful..my hubby and I been living this way for a few years. Fit well and good living .
Dr Terry Wahls strongly recommends high greens, cruciferous and berries to “feed the mitochondria”. See Ted talk
I have not had much hope for a while. I have mostly non motor symptoms. You are so right in regards to quality of life. After listening to your presenation I actually was very hopeful.. I only wish there was a physician such as you that we could see. Blessings to you for the work you are doing.
don't give up, non-motor symptoms are easy to be fixed by persistent fasting and quality cellular supplements, my friend has significant improvement in 6 - 8 weeks time.
@@evonelsie4909 thank you for your response. Please share any insights you might have. 🙏🏻
Sure my friend got this disease in his young age , i don't want to mention the reason in here cuz it's kind of sensitive. However, he started fasting, ketogenic diet for a month and also a high bioavailability German made supplement then his non-motor symptoms were mostly solved, now only left behind are the motor symptoms. He is now combining a special kind of meridian points electronic accupuncture treatment as well currently. @@suzysanchez5773
I don't have PD, my mother does. I have transitioned from keto to keto-carnivore and increased fat intake, eating one meat or fish meal a day. Also i do one 48hr fast per week, after which i feel amazing with sharpness of mind and energy in spades. I haven't felt this good since childhood. I was keto for 4 months with slow weight loss but and some improvement in energy, mood and brain function. But once I eliminated plant food (2 months ago), things improved dramatically. I am doing this to lose a lot of weight (30kg so far in 6mths, 20kg to go). It is extremely effective and EASY because my appetite is very low and craving for sweet things has almost entirely disappeared thanks to consistent ketosis, fasting, almost complete removal of plant food and increasing animal fat intake. The high fat makes easy bowel movements too.
My mother has PD, I want her to try keto fasting, but unlike me, she is underweight and is struggling to gain. So if I am eating high fat (adding cream, butter, suet) and 500g meat/fish per day and my body STILL (miraculously!) mobilises and metabolises fat from my adipocytes, how can I get my mother into ketosis/fasting to get the benefits of that but at the same time INCREASE her stored body fat???
It's a difficult one, but in patients who are already thin (BMI
O
Amazing ❤ I can just say thanks a lot. You are helping a lot of people, including me.
You are a genius ....Fasting is key...let the body repair...it will!
My husband has been diagnosed with PD for 12 months. I introduced MCT oil each morning and replaced breakfast cereal with overnight oats. He has improved out of sight with an exercise regime and semi Leo diet. I think the oil was a great start. The meals I cook are generally low carb and he still eats some carbs. This presentation is fantastic!
My experience as a caregiver .
Proper diet, exercises and sleep. I have witnessed.
12 years ago I was diagnosed with PD follow with a number of prescriptions. Once on med.’s I began to experience severe constipation. There were times I would go on
for days uncomfortable due to my inability to poop.
I came to the point were I decided to take the matter into my own hands. Therefore I started working on healing myself, that meant working from my gut first.
I started on probiotics 248mg one a day. ever since I started I have been moving my bowel every day. that has put me back on a schedule ♥️🕊
glad everything came out alright!
Which probiotics are you using?
Thank you for sharing 🙏
What brand probiotic
What brand probiotic
Gracias por compartir, ya lo pasé a mi tía que tiene Párkinson, ojalá lo vea completo y lo implemente.
Es una esperanza. 🙏
This is amazing and revolutionary! I was diagnosed with PD almost two years ago at age 61. I've implemented multiple strategies for managing it and hopefully slowing the progression. These include cleaning up my diet, exercise, supplements, red-light therapy, high-dose b1, and others. When I first saw this video two weeks ago I immediately initiated a two-day fast and then went 100% keto and intermittent fasting (into ketosis by the second day). I've already noticed an improvement in my mood and a decrease in fatigue. I'm excited to see where this can go longer-term for myself and others with PD. These protocols look to significantly reduce suffering! This is a very big deal! Dr. Phillips, you mentioned that since the study was done 5 years ago and your learning has continued that you would change a few things. Besides what you mention like extending the protocol to 6 months, what else would you change as far as applying what you've learned? Much gratitude for the work you're doing. ~ Brad
Do you take carvidopa/levapoda I’m 39 and I just got diagnosed. I’m devastated but I’m willing to do anything to stop it please
@@Shoshin777 Yes. C/L (Sinemet) is the only pharmaceutical that I take. As far as I'm aware there's nothing that will stop PD for sure in everyone. That said, I know that disease progression can be slowed down, stopped, or possibly reversed for many of us. Mine appears to not be worsening and I continue to see some improvement in a few areas. For example, my sense of smell is back online more of the time. I acknowledge that my experience is not proof applicable to everyone. The bottom line is there's a lot that can be done to decrease suffering and improve quality of life. BTW: I'm now 15 weeks into ketosis, thanks to Dr. Phillips and the creators of this video!
@@bradmaybury3747any more improvements?
I was diagnosed 20 yesrs ago and compares to PD peers, am doing relatively well. (Most have passed away). I have followed my appetite, and for a long time eat a smaller, low proteins breakfast w/fats. I drink a lot of water. Im not hungry for lunch. Later in afternoon, want to eat a muffin. Then don’t eat much until around 11pm. I am hungry for salad and red meat, eggs. I was mostly vegetarian, but seem to need to eat bbq brisket. I don’t crave sweets anymore. I do crave crisp bacon. So i snack on that.
Ive lost 40 pounds in 5 years. 2 years ago, got a puppy. I like functional exercise and destination walking. I dont drive and can walk to stores.
I always feel like i should do better and eat 3 meals/day and go back to a hard gym workout-but I have less pain and better posture when my PT is on vacation. And although Im thin and my medical records say “frail” im solid muscle. Go up and down 6 flights of stairs quickly.
Im watching this video and think instinctively on the right track.
Matt is fabulous.
I'd like to see a comparison of whole foods plant based diets vs keto diets where both use intermittent fasting. Maybe the fasting is the most important...
Thank you so much 👍
Amazing presentation 👏
Cheers Maria! Kind regards, Matt.
I'm always amazed when clinicians and researchers on similar subjects don't cite each other's work. Dr Jason Fung has been promoting the metabolic benefits of fasting for many years.
Thank you! 💯👍
Excellent resource. Thank you so much!! How much has human civilization become its own Frankenstein!!! So, I'm leaning towards the Keto diet...am I wrong?
My husband has been on a Whole Food Plant Based diet for 5 years. No processed food, raw sugar or processed oil. He’s doing well in our perspective. Excellent presentation!
Excellent info! Dr Gundry and Dr Pearlmutter on the same page along with Dr Paul Mason and regarding cancer, Thomas Seyfried, PhD on same page for mitochondria. Thank you so much!!! Sharing this with people who need it.
Thomas Seyfried PhD & team at Boston College have treated only 4th stage cancer of every type including brain cancer for over 20 years with an 85% to 90% success rate. He has filed papers requesting the standard of care be changed. They do not want to use chemo or radiation; it makes it harder to get rid of cancer.
Thank you for not seeing people from pharmacy and food industry.
Thank God for you and those like you!
Dr Roger Seheult has shared on Med-Cram that near infrared light helps with Parkinson's.
Dr Gundry was a money grab!
Just subscribed.
This is just an excellent video. I do have a question. I was diagnosed with PD three years ago. I remain drug free thanks to life changes, primarily diet and exercise. I intermittent fast usually 18 hours a day, sometimes I eat only one meal…..keto. I do enjoy a mug of bulletproof coffee in the morning , one tablespoon MCT or coconut oil plus one tablespoon grass fed butter plus a squirt of Stevia. My question…does that break my fast? One source says no, there are no carbs. Another source says yes, too many calories. Help me!
Hi Chris, awesome protocol you have there. It is not a black and white answer, depends how you define fasting - can be nothing, water only, water/tea/coff only, etc. The aim is to sustain ketosis. Given your goal of improving the PD, the pure fats you ingesting do not break your fast, as they will elevate ketosis if anything. Only the sweetener would be debatable - if it is a tiny suirt, it's probably ok, but no sweetener is the best kind of sweetener if possible. Sincere regards - Matt.
@@drmclphillips , thank you so much for your response. By the way, I have been following your work for two years with great interest. So anyway, I got up this morning, got in an hour of exercise, then made my mug of bulletproof coffee WITHOUT the squirt of Stevia. I had thought that Stevia was the one safe sweetener, but no more in my coffee. By the way, I follow the Wahl's Protocol, level three, keto, very closely for my diet. I am completely convinced it has made a difference, but I have no proof. You are doing the research for that proof. Interestingly, my PD friends (and my MDS) ask what I am doing that I am doing so well. I talk about my diet, exercise, meditation, sleep. About diet....no one wants to give up their desserts, bread, alcohol, processed food....no one
@@drmclphillips❤
No whole grain as oxalates are mainly located in the bran.
Dr Phillips, do you treat patients from Australia?
Any research on keto 🥑🥓🥚🧀 and fasting on memory for Grade 1 to 12?
Dr. Phillips are you aware of the benefits of high dose thiamine for Parkinsons? I have used 2g per day thiamine for 5 years, and fasting/low carb for ten years now. It has kept things at bay. However the constipation and dysautonomia are now so severe that I need to take Mestinon. Probiotics, prebiotics, all manner of laxatives are ineffective. Have ordered a coronet red light helmet from Well Red. I really hope this is all still reversible but I just want to say fasting, keto and a tonne of exercise have saved my life the past ten years. I literally only feel ok anymore if I’m either fast asleep or moving my body vigorously but without the thiamine, fasting I have tremors etc. I’m only 52.
Hi Beebe, thank you for the information. I am aware of the potential for thiamine in PD from a number of sources now, yes. However, it is a single supplement capable of only altering the body's physiology on a small scale. By contrast, metabolic strategies such as fasting, keto diet etc alter the body's entire metabolic state - fuel source for brain and muscle, gene expression in many cells, bioenergetics etc. I favour the latter approaches as having far more potential for good in PD, which I view as a mitochondria disorder. I am not against any supplement, only neutral - if it helps and you can finance it, by all means use it. Sincere regards, Matt.
Do you eat fermented foods like kimchi?
Hope he will test MCT
my symptoms were as simple as a genetic problem with cobalamin .. I take a shit load of methyl cobalamin and jab myself once a month.. misdiagnosed at 45 still here at 66..
How do you feel lmnt salt for fasting with Parkinsons will transcribe to healing. If Mr Fox had had this doctor he would now be in a different condition than currently. As a teen in the 1950's I rode in a car with my friends aunt who had Parkinsons and her hand shaking on the steering wheel was very disconcerting. Many years ago Parkinsons devastated we mortals. But now we have diets to deal with this horrible disorder.
How do I go about getting on the Charco CUE 1 waiting list?
Please visit their website or email support@charconeurotech.com
Dr.Pillips repeatedly said that frequent meals and processed carbs were the biggest changes in the decades associated with the increase in Parkinsons!!!
Surely not; _the introduction of seed oils dwarfs those changes_ .....by miles. When I was a boy (in 50's UK) they were simply unknown, but snacking and crisps/chips were common enough.
Dr. Joel Wallach has also had success in removing the symptoms of Parkinson's for decades using diet and supplements.
Check out his book "Epigenetics - The Death of the Genetic Theory of Disease Transmission"
What do you mean by “adequate protein”. So many different opinions on amount to eat daily!
4 times 40 grams per day, i heard... Also depends on activity...
Share to all doctors
Dr Phillips, How does a person get officially diagnosed with Parkinson’s? My husband is 52 and has had his head and neck MRI and it’s come back normal. So they ruled out stroke or MS. They prescribed him Carbidopa-Lovidopa to use a a tool to help diagnose him. The Dr said that if it helps with his motor issues then it’s probably Parkinson’s, but if it doesn’t either it’s not Parkinson’s or he’d probably up the dosage. He did also order another scan to check his dopamine, but said that the scan was optional. I don’t understand how it’s acceptable to use a drug as a diagnosis tool. He much rather try diet and fasting to see if that makes a difference. He’s had digestive issues most of his life, so gut health is probably a real issue with him as well. His symptoms aren’t that bad that he needs a pill. We live in central Florida , do you know any specialists in this area that we should connect with? Please advise on how to get an official diagnosis.
Hi Lynn, I'm not a doctor, but I do know that a short course of levodopa is often used as a way of distinguishing between Parkinsons (which it will help) and Parkinsonism syndrome such as MSA (which it won't help). My mother was in the latter category and was also offered levodopa as a diagnostic tool.
You could experiment with macuna pruriens as a natural source of levodopa and do the same yourselves. Someone on the Health Unlocked PD forum is having good results with the Piping Rock one which is 15% levodopa. (Note that batches may vary in strength).
I think you would find Dr Hauser (CD; his wife is a dietician; they seem very good at helping patients whom no other doctor has been able to help) in Ft Myers very helpful. He has youtube videos you can check; see Dr Hauser and Vagus nerve.
Hi Lynn - the diagnosis is clinical, so what you really need is a good and confident neurologist. If your husband's current neurologist is unsure, a second opinion might be useful. Best wishes, Matt.
Just been googling about those monkeys as they were so striking - was disappointed to find that there have been contradictory results from a later experiment.
How about oxalates?
I had none of those symptoms before my tremors began
Im interested in drive position. Need link hookup. I have twic card
Parkinson disease is a very terrible illness, my Dad suffered from it for 19 years until we finally got a help and a medicine that truly works that helped treat, cure and reversed all his symptoms... My Dad is well again..
For fasting in relation to a woman's cycle, check out Dr. Mindy Pelz, she wrote a great book called "Fast like a girl"
I would suggest that the “health” community will be forever indebted to Matt. I doubt that SAMS, Sad American Medical System, will fight him to the death. Too much money on the table!
That is not a chimpanzee at 30:00 some type of Macac
I found it a bit disconcerting that he didn;t correctly identify the monkey as a macaque - probably a rhesus macaque
Stephen Pinney has research on keto 🥑🥓🥚🧀 in sports
Dr Mindy Pelz wrote a book "fast like a girl" for women
😢
Parkinson disease is a very terrible illness, my Dad suffered from it for 19 years until we finally got a help and a medicine that truly works that helped treat, cure and reversed all his symptoms…My Dad is completely okay and healthy now💪🏼💪🏼
How did you help your father?
Yes what you done
I got the treatment from Dr Madida on CZcams
Click and search #DrMadida for medicine.
What helped your dad 🙏?
Of course this is unrelated to effectivity or quality of Dr Matthew Phillips described Metabolic strategies but one can find calling such distinguished and meritoriuos to medical experiments animal i.e. Rhesus Macaque a Chimapnzee utterly propestrous.
Hi! Yep, it was so long since I read the study that I misnamed the primate, my mistake entirely. It was pointed out to me soon after but alas, too late to do anything about it. Thanks for letting me know, Matt.