Type 1 and Type 2 Respiratory Failure Part 1

Respiratory failure is failure of the respiratory system to do its job properly. The job of the respiratory system is to add oxygen into the blood and remove carbon dioxide. Failure of either one of these, manifesting as low oxygen in the blood (hypoxia) and high carbon dioxide in the blood (hypercapnia) respectively, constitutes respiratory failure.
Of the two respiratory gases oxygen level in the blood is the more fragile. Loss of function of a relatively small portion of lung tissue, for instance due to a localised pneumonia or a PE can result in a radical drop in blood oxygen level. Meanwhile carbon dioxide level is unlikely to be significantly altered if only a small portion of lung is non-functional. This type of respiratory failure in which oxygen is low but carbon dioxide remains within the normal range is called type 1 respiratory failure and typically arises from a localised disfunction of lung tissue rather than a globalised respiratory system disfunction.
In contrast Type 2 respiratory failure is when carbon dioxide level is too high within the blood. For this to occur it typically requires widespread disfunction of all of the lung tissue or at least the vast majority of it. It is a more severe form of respiratory failure and is typically much more difficult to treat than type 1 respiratory failure which can be treated by putting the patient on oxygen (i.e. raising the FiO2) until the disease process causing the disfunction has resolved. Conditions such as widespread pneumonia, interstitial lung disease, asthma and COPD can cause type 2 respiratory failure as they cause widespread disfunction of all of the lung tissue.
In this video I discuss how type 1 and type 2 respiratory failure are diagnosed and how they are treated. I also discuss examples of respiratory conditions which can lead to respiratory failure and explain in detail how they lead to the respective types.

[@medicalstudybuddy2964]

Thank you! You have answered soooo many of my questions!! This is a golden video and u are amazing!!

[@User-to7nb]

"proper respiratory failure " is the most British sentence I've ever heard

[@doctorposting]

im american and now i wanna start using this phrase 😂😂😂

[@senanuavadzi9463]

Each haemoglobin molecule is made up of four subunits, therefore four binding sites

[@drkrypt0]

You’re so awesomeeee!! Thank you

[@user-yy8nx4wo4s]

Thanks
Are you can give me a link of guide line to type1
Pls

[@AamirKhan-ye2nl]

is the pneumonia portion where gas exchange isnt happening considered a shunt?

[@shinishaji3557]

👌

[@Ruqaya_pearl]

Thank you very much

[@jojucherian6238]

Excellent!!

[@cojut]

Nice explanations, but a hemoglobin doesn't carry just 1 oxygen, it carries 4 :)

[@TheAtheist22]

Good presentation. The only thing, you should replace hypoxia with hypoxaemia. They are related of course but they are not the same.

[@jimmyolomi1253]

Each molecule of hemoglobin contains 4 sites for combination with molecular oxygen; 1 g of hemoglobin combines with a maximum of 1.36 mL of oxygen.

[@User-to7nb]

but seriously, thanks dude. I learned and do appreciate the effort.

[@elliotnicholson5117]

Thank you for watching and for commenting.

[@claredempsey2086]

Thank you so much, this has explained such a lot

[@AsemMIsmail]

I think you meant kilopascals not mmHg for partial pressures (kpa used in the UK)

[@reyos2591]

Also, pco2 is low bécause, co2 can diffuse much better

[@thechannelstrip]

so many beautiful pictures lol

[@queen1990ful]

Great info but why are you whispering?

[@googleacc6022]

short video he said

[@thechannelstrip]

4 binding sites

[@HennaFoxUK]

nice accent ;) sounds like russian

[@Sunnyanser36]

wasteof time