Treatment patterns in patients with AL amyloidosis after failure of frontline Dara-VCd

In this video, Saurabh Zanwar, MD, Mayo Clinic, Rochester, MN, discusses treatment patterns in patients with light chain (AL) amyloidosis after failure of daratumumab, bortezomib, cyclophosphamide and dexamethasone (Dara-VCd). He highlights that patients with a suboptimal response to this regimen have limited treatment options, with an option to switch the VCd component. Dr Zanwar then discusses the findings of a study which found that patients with a suboptimal response to Dara-VCd either switched to a daratumumab- or venetoclax-based regimen, or underwent autologous stem cell transplant (autoSCT). This interview took place at the XIX International Symposium on Amyloidosis (ISA) in Rochester, MN.
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