How optimizing circadian rhythms can increase healthy years | Satchin Panda | TEDxBoston
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- čas přidán 7. 06. 2024
- Over millenniums human body has been intricately programmed to adapt to the predictable daily changes in light, temperature and food availability. Circadian Biologist Satchin Panda is working to discover biological principles underlying the such circadian plasticity of human body and leverage it to reduce the burden of disease and increase healthy lifespan. Learn more about how circadian rhythm discoveries can transform human life and catalyze redesigning our world. Satchidananda Panda
Professor Regulatory Biology Laboratory at Salk
Dr. Satchidananda Panda, a professor at the Salk Institute for Biological Studies in La Jolla, California. Satchin’s work deals specifically with the timing of food and it’s relationship with our biological clocks governed by circadian rhythm and also the circadian rhythm in general.
Professor Panda explores the genes, molecules and cells that keep the whole body on the same circadian clock. A section of the hypothalamus called the suprachiasmatic nucleus (SCN) lies at the center of the body’s master clock and gets input directly from light sensors in the eyes, keeping the rest of the body on schedule. Panda discovered how these light sensors work, as well as how cellular timekeepers in other parts of the body function. He also uncovered a novel blue light sensor in the retina that measures ambient light level and sets the time to go to sleep and wake up every day.
In the process of exploring how the liver’s daily cycles work, Panda found that mice which eat within a set amount of time (12 hours) resulted in slimmer, healthier mice than those who ate the same number of calories in a larger window of time, showing that when one eats may be as important as what one eats. If the benefits of this “12-hour diet” hold true in humans, it could have profound impacts on treating overeating disorders, diabetes and obesity.
The circadian clock, he found, even mediates the immune system. Mice with a crucial circadian molecule missing had higher levels of inflammation in their bodies than other mice, suggesting that genes and molecules involved in the circadian clock could be drug targets for conditions linked to inflammation, such as infections or cancer. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx
I have had a bad sleeping pattern and circadian rhythms since I was a teenager and I can confirm whatever the doctor said. Though I'm only 33 years old, I have pre-diabetes, high blood pressure, overweight, anxiety, high cholesterol and triglycerides, and blood concentration. I never ever remember having a regular sleep pattern. My friends, save yourself before it's too late. Unfortunately, there aren't many resources about this and I'm so glad Doctor Satchin has invested in researching this topic. This is a really big deal but not talked about enough.
There is an app with a free trial that helps you learn your best sleep and wake times. It helped me tremendously.
I don't believe it's too late! The body can heal as we make small changes now.
Thanks for the positive energy. What's the app's name? By the way, I have almost fixed my sleeping time. Now I sleep between 11 to 12, 1 AM at the latest in rare situations. I used to sleep 2-5 AM. Now I'm working on my wake-up time and seeing improvements there as well. So you are right! It's never too late!@@scottandrebeccalaird8577
@@scottandrebeccalaird8577what's the app called?
I love the part where he mentions how his team discovered this, and my 94 years old grandma has been living exactly like that her entire life. Plus she is very strong and healthy at 94!! I guess we should all take this talk seriously. ☀️
Interesting!
I laughed out loud when he said his team figured this out when yogis (he’s probably from India) have known this for thousands of years.
An awful lot of cutting edge science about health and longevity lines up with what our grandparents would say. It’s all wisdom that’s been learnt over millennia and then discarded in the modern world. Early to bed early to rise as one example.
@@MetalSlug-ev5wuon the contrary, you'll notice he said nothing about a specific bedtime. Everyone is different. I was tested for my circadian rhythm and my ideal bedtime is 1:15 am.
I do agree that the previous generations lived with much more wisdom and healthy lives. Brain tumors in children was not a thing when I was young! Bodies, families, and culture are eroding. Even those who deny our Judeo-Christian ethics can clearly see the demise of our Western culture which lines up with leaving our roots.
@cofinance9 - I believe you may have missed the point. His team has the scientific testing to back up the old wisdom. Since people often think they need scientific proof now, this is very important work. I did not hear him claiming that it's new information. Only that he's been on the forefront of the current research, which could help bring about much needed change..
So interesting… in fact anywhere in the rural areas of the world , you’ll probably see healthier , happier people because they are so in tune with the movements of Nature . Living in fast-paced urban India , most of us have destroyed our cicadian rhythms ,right from when we were kids studying till late into the night till now when we’re binge-watching our favourite shows when we should be asleep.Modern life has taken a toll on our health , but we’re so entangled in it, that we can’t just throw everything to the wind to do what our grandparents knew how to do . All we can do is try .🙏🇮🇳
Absolutely brilliant! Thank you so much Dr Satchin Panda.
one of the best videos on youtube and by Ted Talks. Thank you Dr. Panda.
The best video ever. I learnt soo much. I actually watch and discuss with my patients
Thank you for your wonderful and hopeful presentation!
Thanks Dr Panda for the amazing talk with good comparisons of our body to a car.Its so true about the circadian rhythm
So enlightening. Thank you so much.
Excellent information. Thank you.
Thankyou Dr. Panda
This is amazing! I doubt this is a more important TED Talk than this. Thank you Dr. Panda!!!
Check out his interview with Rhonda Patrick on YT.
@@NikoHL 2:31
Simple. Sincere. Scientific. Super Dr Panda
Thank you so much. Greetings from Guadalajara Jalisco México
Great information. Thank you for sharing
Great talk Satchin
Enjoyed! Thank you great advise
Thank you doctor!
Wonderful talk. Reminds me of old Douth Indian traditions.
I love and like this talk so much, agree on everything, but not on excersising in evening ....early morning is best, and possibly at empty stomach (for example a brisk walk)
Thanks you so much 🙏
Very interesting lessons...great presentation. Thank you Sir!
How about we use, "Have a perfect Circadian rhythm" instead of expressions like "goodbye", or "God bless you"...etc???
Great presentation!!!
Great video, thanks
Fantastic !!
Excellent information!
Thank you for sharing this
In school we have learned about how important our circadian rhythms are, and how our biological clock really does make sense of the things going on in our lives. Growing up, I used to think that it was so crazy that everytime it got dark in the night I would feel more and more tired. Satchin Panda in this Ted Talk has given his audience a variety of ways in which they can improve their circadian rhythm. This is following the ethical principle of beneficence and respecting our patients autonomy in the sense that we aren’t making the options end all be all types of situations. Instead Mr. Panda is trying to find a common ground with people on many different aspects. However, is there any research where people have just done one thing here and there which seemed to be helpful? I also don’t know if increasing the biological clock would be helpful if scientifically our bodies progress to deteriorate step by step as we get older.
This guy is such a genius..👍
Path breaking❤️🙏👍
This is so true.
Dr. Huberman, wholeheartedly supports Dr. Panda and his work asserts that 10-20 minutes of light first thing in the morning is key to circadian rhythm. Dr. Panda, you talked about 30-minutes of sunlight, but is early morning sunlight particularly important? Thanks for your incredible and game-changing work!
In his book he says that light during the day is important, especially in the morning, and to avoid it close to bedtime. Hope that helps!
What’s the single most important thing I can do to optimise my health?
- Watch the AM every day
As soon as you get off the bed
Go straight in the open sky or atleast a place where you can see the full sky
and let the ☀ light program your eyes for the day
But most check their phone as soon as they get up. Not good.
Morning Sun ☀ gives you Infrared & Visible light. There’s no Ultraviolet in the early AM. The color temperature is around 1800K.
Your each eye has 125 million + photoreceptors.
Morning blue light from ☀ is what wakes you up by raising your cortisol and is activated when blue light hits your pituitary gland. It sets your circadian rhythm for the day.
Morning light sets off a cascade of hormones and neurotransmitters which make you feel good.
Every human’s got around 25,000 sunrises in their lifetime. How many have you seen?
/ze_rusty
What makes Huberman an expert on this topic??
@@nonrepublicrat He isn't.
Dr. Huberman gives credit to this man when he speaks of these benefits.
Wonderful
Thanks
How can we determine the “right” time of day to take certain medications, treatments, or surgeries?
Thank you!
I'll be taking this advice to the grave. Ty sir
Your narrative is intricate and evocative; much like a book that was intricate and evocative in its thematic treatment. "Better Sleep Better Life" by William Brook
This is all very well explained in different words in Ayurveda (Science off Life ).We in Bharat (India) have been living this life from ages.
-_-
Yes correct
May be you are right but how many people follow auurvedic texts ?Why are majority of Indian adults are Sikh having one or the other health issues? May be because we need to hear it in English with some fancy terms like circadian rhythm. Old wine in a new bottle? As long as it does good to the listeners we should be grateful to Dr.Panda.
I go to bed late after midnight, but I normally keep a regular schedule. Also sleep for 8 hours, but do you know if that has effect on growth hormone release?
What about daylight and the circadian rhythm? Doesn't that also affect the sleep/eat/productivity rhythm? What about the different seasons and on which part of the world you are? Spring for example is a time period when the organism wants to "free" himself from the burden ""gathered"" in the winter. What about the position of the moon? I am interested in reading more about Dr. Satchidananda Panda works. Thanks.
Read his book and your questions will be answered
Why is there so much background noise? Was he presenting in the lobby?
Now this Circadian rhythm popular in south india by Dr.Pal. It is working.
Sir i followed intermittent fasting and lost weight and thanks for your guidance but my sleep quality is not good. Please guide me on my sleep and my tummy is not reducing
Rest, sleep, fast are the necessities the body needs to live long with out medicine.
👍👍
🙏
Ayurveda explained importance of daily routine callled Dinacharya in Ayurveda 5000 year back which is now called circadian rhythm
Absolutely, AYURVEDA IS BRILLIANT 👏🏼 THANK YOU FOR RECONFIRMING WHAT OUR ANCIENTS HAVE BEEN PRACTICING HUNDREDS OF THOUSANDS OF YEARS . HOPE YOU WILL CONTINUE TO REDISCOVER LIKE HOW YOU DID ABOUT INTERMITTEN🎉 FASTING , BRING TO LIGHT THE MANY WONDERS ON AYURVEDA , YOU WONT NEED ANOTHER DRUG & PRAISE AUYURVEDA TOO!
And When did he mention ayurveda ?? 💀
How about drinking coffee first thing in the morning? Does that harm our circadian rhythm?
Guardian Angel 😢
I wonder if taking bipolar meds at the optimal time would give better outcomes.
Ayurveda knows this for thousands of years.. I am happy science is catching up!!! :-D
Nope actually you really want to understand science of body then you must look into quran coz Islam teaches us how everything from fasting to dieting and foods mentioned and exercise and every stuff is already present and intermedent fasting 2 day a week and much more and even much complex things about human body is mentioned and explained in quran compared to ayurveda 😉
A simple example is ablution done by Muslims 5 times a day by Muslims reduces external environmental aggressors and today people discovered cold water face dip and rinse but in islam Muslim doing it for many years for morning prayers like 5:00 am is water is much colder and Muslims do ablution 👍
@@mr.snipersheku3656when u don't know anything about Ayurveda 😂😂
Hey what about light excersise before bed? like 2 hours before bed?
Read his book!
Its a common rural indian practice what he is calling a research.
Not clear how to manipulate circadian rhytham pl send your protocol
Hello dr🙏
My age 60. Weight is not reduce. Y dr
Try whole food plant based diet
3:53 , 8 : 38
Intermittent fasting, and living according to the moon and sun movements, even having a calendar that uses the moon as its guide and more are all already what the guidance of Quran tell us to do in Islam. Although not all Muslims follow it unfortunately.
Most Circadian Rhythm charts are wrong. They show fixed times, like midnight and noon at 12, and morning and nightfall at 6. The times of these phases change daily, like sunrise, sunset, sun peak and midnight. You can use Salah charts instead. As Muslims, we have 5 obligatory daily Salah, that help us sync our Circadian Rhythm with nature. People have been doing it for millennia.
South Indian
Panda is an Oriya surname.
Aaj ke Aapna ke Bhalo Laagche 😯 🙇🏻♀️ 👍 🌹. Prottek din shadda ya haalka rong color kaapor porben👌'Gala Bandh' suit ya Punjabi churidar kurta set (khadi jacket)- like PM Modi, ya Safari suit, ya Dr.'s jacket coat, or Gola Bandh outfit.
Apnar koi ekta indian accent dhora jaina.
"LIVE" boja jache Na. (elocution tuition practice korben...Bhalo lagche.) Bolun : "Live ( Laive) " ... Living Live animals 🙏💐
8 hrs of sleep, I don't agree. BTW nice one
Ha ha his team discovered this 🤣 😄 😆 😂 😀. Ayurveda clearly explains all this
What's with the distracting background noise? Sounds like no one there is listening, but are moving furniture and talking.
Exactly 💯
I disagree - surely it's best to eat something as soon as you wake and preferably include protein? This is because your body's in a fasting state when you wake so protein ASAP gets your cortisol level down, so you feel better straight-away. For example, if you are an anxious or depressed person, I imagine that denying yourself food for even only 1 hour is a really bad idea because you're starting the day off on the wrong foot, so to speak.
Fasting is actually extremely beneficial for anxiety.
@@jazzhandsdan207 That's illogical because your cortisol levels rise when you're fasted. That should make any anxiety you have increase. I've noticed that Jordan Peterson talks favourably about fasting. However, he's not physically fit and he takes a lot of medications so he's not in a normal situation.
Thackle 😂
1) 8 hours in bed
2)
1) 8 hrs in bed -sleep
2) avoid eating for at least an hour after waking up.
3) Time restricted eating (IF) eat with 8-12 hours, fast for 16+hrs
4) Get at least 30minutes day light
5) Daily exercise in the afternoon
6) Winding down; avoid food/dim lights 2-3 hours before bed
@@zipporahwanjiru8598 so smart
maybe staying outdoor will fix his eyes
These are exactly what religion Islam said 1400 years ago, Alhamdulillah.
listening to this indian accent already took 5 years from me
What's wrong with his accent?😅 Its certainly not Indian accent 😅..
Good information. But accent is full of north, south indian, fake American, fake british, villager mix accent.
Why can’t he talk in Indian accent. Why one word out of 1 sentence sounds like american and the other sounds like 😂 let me not say.
keep complaining. U know not everyone can fake an accent perfctly. keep complaining while he is a doctor treating patients.