Hurler Syndrome and Hunter Syndrome | Lysosomal Storage Disorder Mnemonic

Hurler syndrome and Hunter syndrome are the lysosomal storage diseases known as the mucopolysaccharidoses. Hurler syndrome, also called mucopolysaccharidosis type I (MPS I), is caused by a deficiency of alpha-L-iduronidase. Similarly Hunter syndrome, also called mucopolysaccharidosis type II (MPSII), is caused by a deficiency of iduronate-2-sulfatase (I2S). In both diseases, the mutations lead to the accumulation of dermatan sulfate and heparan sulfate, the presence of which in body tissues leads to a variety of clinical findings. Both diseases are similar, but Hunter syndrome is a less severe form of Hurler syndrome. Hunter syndrome can be clinically differentiated by a lack of corneal clouding but with the additional finding of aggressive behavior. As an aside, Hurler syndrome was formerly known as gargoylism, as build-up of mucopolysaccharide leads to the coarsening of facial features.
Learn about Hurler Syndrome and Hunter Syndrome (Mucopolysaccharidosis Types I & II) with Pixorize's visual mnemonics and memory palaces. Part of our Lysosomal Storage Diseases playlist for the USMLE Step 1 and NBME shelf exams.
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[@jayjoejeanz]

My daughter has MPS 1. She received weekly enzyme replacement until her successful bone marrow transplant at 15 months old. She is now 7 and doing very well.

[@tamisims6780]

My Gson has MPS 1HES 11MOS TESTING FOR BONE MARROW TRANSPLANT NEXT WEEK

[@jayjoejeanz]

@@tamisims6780 Thank God! The sooner he gets the BMT the better! God Bless and good luck from Canada.

[@tamisims6780]

@@jayjoejeanz thank you we still going thru the acceptance part ya know this is hard

[@RNcooley]

Great video and I like the fact that you focus on key topics that Skethcy does not cover.

[@wem3121]

I subscribed even before I finished the video. This is GENIUS! I wish you can get more subscribers with those quality videos. Thank you

[@alituraabi512]

keep making these videos they are awsome

[@Pixorize]

Thanks for the support! Please share with your friends if you like them!

[@lisagonzalez2902]

Another brilliant video. Thanks a lot!

[@meistermd7229]

YES! More for the Lysosomal Storage Diseases! Soo good for STEP 1 prep

[@Pixorize]

Thanks! Be sure to check out our website for more videos (and the rest of the lysosomal storage diseases)!

[@omarmadani2291]

Pleeaaaaase siiiiir .. keep on making these videos ...
I assure you they will be more popular than osmosis

[@carolynstolte1437]

Definitely keep making these, they're awesome. Thanks so much! :)

[@JoseHernandez-lk9ov]

why has this video not gone viral? its amazing!

[@Pixorize]

Thanks Jose! And we'd certainly love your help in spreading the word. Tell your friends, so we can keep making great content--virality here we come!

[@sametkucukcolak4157]

thank you so much , this video is so beneficial

[@ainievale795]

Very helpful.Keep up the good work

[@Chriskay021]

This is sooo helpful!

[@cooldawg891]

thank you so much for all of these! I was looking for a sketchy-like video for biochem since visualizations help me learn and I'm so happy I found you guys. such a help for step 1, much better than reading that hefty first aid chapter

[@erkneverdie]

You GUYS are the best!!!!!

[@johnrmark]

Another excellent video, but it would be much improved if dialog boxes were superimposed on the images while the narrator described the mnemonics. This helps follow along with the hard to pronounce words and makes subsequent reviewing of the video much more convenient. Please consider re-uploading with these changes to match your other great high-yield videos!

[@jennarivers9499]

This is great! I wish I had this during my basic science years.

[@Pixorize]

Thanks Jenna! We wish we did too :)

[@mahawa.6647]

you guys are genius.

[@user-wv7se3ko9x]

Oh my goodness
Sooooo helpful
Thank you ❤️❤️❤️

[@drmumtaz6621]

Cant believe u not having subscribers in millions…brilliant❤

[@Pixorize]

Thanks for watching ! 💜

[@revanthjosh6925]

Oh god. This z so helpful plz keep doing ❤

[@d8457]

Excellent !!!!

[@imeeeswonderland3783]

Thank u 💞

[@hagarkhallaf991]

Thanks a lot :)

[@Pixorize]

Thanks Hagar!

[@mengjiawu8686]

hi the video is great! how often do u upload new videos on for the premium subscription and is the payment an one off thing or do i have to pay more to see the new videos??

[@Pixorize]

Thanks Mengjia! Our team tries to release 1-2 new videos per week. A complete subscription includes access to all new videos on our website. Thanks for watching!

[@esraayasir5930]

Veeeeeeery useful 🔥🔥🔥🔥

[@behayluyibe3940]

This is how the memory works, keep it up

[@Pixorize]

Thanks for watching! Great to hear that it was helpful for you

[@deepakshikhurana9662]

THIS IS PHENOMENAL!!! PLEASE DENTAL VIDEOS FOR NBDE'S !!!

[@Stella-lr7nm]

ohhh man that was awesomeeeeeeeee

[@donuyi8416]

X marked d spot = hunters

[@incompatibleTypes]

It was great, but I think you’re missing the cardiac complications. According to Robbins, it’s an important cause of death.

[@mornobells2375]

Biochem sucks 😂

[@traumagotmesick6750]

Sorry, could not watch it till the end.. too science-fictional...