Structure of a Skeletal Muscle Fiber || Sarcomere, Thick filament, Thin filament, Actin, Myosin etc

📝 Find notes here: www.nonstopneuron.com/post/st...
🌐 Explore our entire animation video library at: www.nonstopneuron.com/
Video Summary:
Skeletal muscles are made up of fascicles which in turn are made up of muscle fibers or muscle cells. Characteristic content of muscle cells are myofibrils, T tubules... and sarcoplasmic reticulum. Myofibrils are an array of sarcomere arranged linearly. Its made up of thin filaments and thick filaments. Thin filaments are made up of actin, tropomyosin, and troponin. Thick filaments are made up of myosin 2 molecules. These filaments are the contractile machinery of the muscle. The myofibrils are surrounded by T-tubule - sarcoplasmic reticulum system. T tubules invaginate from the cell membrane and branches to make a network of t-tubules around myofibrils. Associated with it is the sarcoplasmic reticulum that stores Ca. Together these T tubules and sarcoplasmic reticulum play very important role in excitation-contraction coupling. Dispersed throughout the cytoplasm are mitochondria that supply ATP for muscle contraction.
📽 More videos on Musculoskeletal System:
• Neuromuscular Junction & Transmission: • Neuromuscular Junction...
• Pathophysiology of Myasthenia Gravis: • Pathophysiology of Mya...
• Treatment of Myasthenia Gravis: • Treatment of Myastheni...
● Follow me at:
• Instagram: / nonstopneuron
• Facebook: / nonstopneuron
Chapters:
00:00 Introduction
00:17 Muscle Fasciculus
00:24 Muscle Fiber (Myofiber or Muscle Cell)
01:29 Myofibrils
01:40 Sarcomere
02:09 Thin Filaments (Actin, Troponin, Tropomyosin)
03:49 Thick Filaments (Myosin)
05:34 Bands: Light Band & Dark Band
06:42 Cut Section of Sarcomere
07:33 Z Disk
07:50 Striated Appearance
08:27 T-tubule Sarcoplasmic Reticulum System
08:41 Transverse Tubules (T-Tubules)
09:24 Sarcoplasmic Reticulum (SER)
10:38 Triad Junction
10:52 Calcium Release Channels (Ryanodine Receptors)
11:31 Other Organelles (Sarcoplasm, Mitochondria, Nuclei, Sarcolemma)
12:35 Summary
Dr Vipul Navadiya
DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.

[@gen_edits]

The quality of your content is way superior than any other. This is so clean and neatly explained. Never understood the arrangement of Actin and Myosin in 3D (6 Thin filaments surround Myosin part). Now its crystal clear. Thank you❤

[@NonstopNeuron]

Most welcome 😊

[@aadi2625]

​@@NonstopNeuronIs dark band made of both actin and myosin? In guyton it is written - *The light bands contain only actin filaments and are called I bands because they are isotropic to polarized light. The dark bands contain myosin filaments, as well as the ends of the actin filaments*

[@neetdose8638]

​@@aadi2625what you said is absolutely true...😊

[@MuthuThala-ih2wu]

​​@@aadi2625isotropic
Iso - same
Tropic- turn (like turn around a sphere, ex: tropic of cancer and Capricorn) which implies an change in term of direction.
Combine both words.
Iso + tropic
Which implies that no matter from which angle we measure the physical properties remain same.
Which is obvious it has only one type of filament, so obviously no change in physical properties..
Anisotropic literally means
An- No, absent
No isotropic,bcoz it has 2 different types of protein filaments with entirely different sequence of amino acids and so the physical properties changes when we measure in different angles..
So light band - Isotropic band
Dark band - Anisotropic band

[@strawberry_milk--]

Outstanding animation/explanation- breaking it down but not losing the details. Thank you!

[@vanshikasharma3331]

This lecture is wayyyy tooo underrated.

[@NonstopNeuron]

Please share it with all your friends and colleagues. It helps a lot. Thank you.

[@modestwomen]

You are so underrated. I watched many videos on this topic but this was the best one.

[@NonstopNeuron]

Thank you so much. Please share our videos as much as you can to support us. That's the only way we can grow fast. Thanks.

[@fujrii_10_46]

Is there anyone who's watching this for neet exam?

[@manasaguda3859]

Yup

[@Aman_khan004]

Me

[@keepsmiling3155]

Yea

[@roopanprakash01]

Me

[@BharaniVcrinkl]

Neet ------->vet😅

[@cornelwilson1066]

Thanks a lot.....This has helped me understand in 14 mins what I would have taken ages to understand while reading a book

[@zubiyanoori924]

I was able to write my answer so precisely and properly only Because I have watched this video...Thank you so much for helping me out🌺🌺

[@thorfinn.believe]

Soooo helpful
Thankyou so much for making this engaging video ❤

[@kiyan1198]

So nice having you creating these animations ❤

[@NkKhanEdits667]

A mind blowing and fantastic lecture about skeletal musle ever

[@sabeel199]

I have studied this chapter lots of time my my concepts was not clear about muscle fibre and muscle filament
But thanks to this lecture today all my doubts are clear

[@rumirumi4792]

Thank you sir .. . love from Pakistan 💗

[@user-fe9rd7pw1b]

This is insane to me how i'm able to understand completely everything you're saying vs.. watching my teacher videos and in her lecture class and I be so lost! Thank you so much! Now you're my go to for A&P!

[@user-mw6ck4oe8e]

Same here

[@cricketshorts1.0]

Best lecture on this topic ❤

[@CutiePie-on5qc]

O my God this was mind blowing you got an ability to explain such technical topic in simple words ❤❤❤bravo thanku so much for such precise knowledge

[@natalieibnouali2474]

your videos are amazing !!!

[@gamingwithpranav1266]

That was brilliant brother 🔥Thank you so much👍

[@user-lq3pu1lf3e]

this is such a well made explanatory video!! it's well organized and helped me understand my text source

[@user-lv9rw6mu8r]

Bro became an end of my research, finally ❤

[@Idkwhattosay.777.]

Loved the explanation. Would come back very often for such amazing animation . Great work ❤❤❤

[@user-th5xo9ls6b]

the best explanation using 3d made crystal clear thorough analysis. thank you very much

[@khuteihc]

This is too good, omg!❤❤❤

[@dil_ki_beat]

Huge ~~~~huge respect 💯 sir for you .
You explained beyond understanding of all the teachers. I'm so crystal clear for this topic.
Thankyou so much ❤❤❤

[@magicwings3212]

Wow i understand all about skeletal muscle 🎉🎉
Thanks 🥰

[@AinaMehtab]

I was Soo confused all my concepts are cleared through this video God bless you and thank you

[@adog6126]

Thank you. My teacher explains things with chicken-scratch writing and drawings. This makes things easier to understand.

[@jahanasherin3129]

Amazing.... Description ❤️❤️❤️❤️🤍🤍thank you💜

[@sahasomdeb5051]

Amazing sir.... Your proper explanation with animation is just awesome.... Truly respect from heart 🙏🙏

[@winxclubflora8446]

Thank youuuuuuuuuuuuuuuuu sirrrrrrrrrrrrrrrrrrrrrrrr. Very helpful u made xtremely hard topic easyyyyy

[@odessaaudry4264]

Thank you so short and precise

[@meowmeow-dw3bi]

Best video on this chapter. will be suggesting to others. keep up the good work.

[@pratishrutinayak]

We love you so much sir what a masterpiece is it!😌☺️

[@drmdmirazulislamislam1499]

A wonderful video ...thanks for helping us ❤️❤️

[@samikshaajmire8284]

Crystal clear 😊

[@user-hf7lc3zv3y]

I was stock with this lecture you saved me my words cant descripe how iam thankful to you god bless you

[@J.R005]

It was very easy and animation are easy to understand 😊😊

[@sportsknowledge4200]

Super method of teaching...thank you🙏

[@kb8qg]

Thank you !!!! 💜
Literally your explanation is amazing and more helpful and clearer than my doctor’s explanation 🇮🇶❤️

[@pallavitalesara6816]

First time in my life i have understood this topic so well ...thank you so much ❤

[@user-mw6ck4oe8e]

I studied the whole Ch but these concepts weren't clear, Now I'M GETTING THE REALLL FEEELLL!
100% CLARITY RN🎉

[@medstudent8050]

Great animation
Just amazing ✨🙏

[@AnjaliAnjali-lk9zt]

Thanks u sir❤

[@nidaqureshi2]

Thank you soo much Sir. Your amazing video saved my day👍🏼👏🏼

[@Peace..255]

This what i needed
Thanks for such a wonderful explanation

[@user-co7lt7dv1m]

The best video I have ever watched ♥️♥️ I understand all things you discussed thank you so much💕 I hate the slides📚

[@chiamakavivian7629]

Thank you!🙏

[@dhruvdangaich]

Best video ever seen on this topic ❤

[@soalihafatima4266]

Excellent video!!

[@user-dt1fb7yx7o]

Such a brilliant video .

[@sinip8886]

Very helpful ❤️

[@abdullahbokhari4136]

Thank you sir...helped me alot...cleared my doubts

[@user-gv7ps5bg5w]

Amazing man

[@jayanthganta4594]

excellent.thankyou soo much

[@elisabetarrushi3523]

Thank u very very much for the information.
After many searches for such occurate information ,finally found it 🙏

[@NonstopNeuron]

Most welcome. If you found it helpful please share it with your friends and colleagues too. It helps them as well as me. Thank you 😊

[@hry727]

I have gone through lots of videos related to this topic and most of them made me more confused about this..thank God I click on this one now I'm satisfied 👍👍 sukriyaaa

[@NonstopNeuron]

You're most welcome

[@laughter44]

It's very good and your content is comprehensive

[@francescabaysa1773]

AMAZING!!

[@christianahfolakemi8507]

This video is one of the best video to ever watch ❤❤❤❤❤❤ thank you

[@burakozvit7480]

Best Ever Vedio on this topic ...do more ❤

[@dindaelvina7103]

this is very helpful for me. thank you so much!

[@NonstopNeuron]

Glad it was helpful!

[@kenaTaresa]

Bruh thank you! You r life saver

[@taera7302]

thank you so much for the video

[@ammarasattar7809]

It's too amazing to watch this video ❤

[@rakshamoksha8659]

Very nice 👍🙂

[@raheelashraf7613]

Amazing video to understanding this topic very helpfull you and keep it up bro

[@hrithishc6398]

Thank you so much. This topic haunted me so much

[@dr.sankarrakeshmalakar7048]

very much appreciable ❤

[@Unknown-zc2nv]

Completely satisfied with this video...❤

[@ShaoorBedaari]

thank you so much for the great vedio ,

[@lifewithasharib1407]

Amazing

[@kjworld6462]

Really it is very helpful thank you so much☺️

[@ayeshaalvi2315]

It's a really really helpful video.Thankss aloot sir

[@Dipali_ShaRma_07]

ThaNkYou so Much such a nice and video and very easy to understand thanks

[@roqaya3]

The words are not enough to thank you, God bless you

[@NonstopNeuron]

Thank you so much 😊

[@motivationspeaker2654]

Excellent sir

[@psreenu7439]

Ultimate Presentation 👌

[@TricksandTips-hf8qu]

Best explanation

[@alirazakhan5392]

Thank you sir

[@prodiptabhaskardey1853]

Thank you

[@zay4ali318]

Thank you very much

[@user-dv8gc4rn5m]

Very helpful ❤❤
Keep going

[@rajneshkumar4679]

Storied muscle kya hai

[@deen_over_dunia297]

Thanks

[@ibrahimnasir9342]

Awesomeeee 🎉🎉🎉🎉🎉

[@roopahiremath5406]

Thank u 😍

[@sheyla2737]

Thanks, your explanation was the best

[@NonstopNeuron]

Most welcome 😊

[@teamantibody6312]

Best 💙

[@mayaskaaa]

amazing explanation !!!!!!!!!!!!!

[@NonstopNeuron]

Glad you liked it! If you feel the video deserves it, please share. It helps me as well as the people you share it with. Thank you.

[@ashima2857]

Besttttttt🔥

[@dr.strange7514]

Sooo good❤ . Thanks a lot for this detailed video sir

[@NonstopNeuron]

Thank you Doctor Strange. Your movies are also very good. Thanks for that. 😜

[@unscholarsacademy8532]

TOOO MUCH EASY TO UNDERSTANT

[@sharmila6721]

Vera level

[@HabibaMohmed-wu8vt]

God bless u

[@Dhanalakshmi-fk2hv]

Super bro underrated best quality teaching

[@NonstopNeuron]

If you feel so, please share words about the channel to all your contacts. It will help learners as well as us. Thank you 😊.

[@Dhanalakshmi-fk2hv]

Sure bro

[@abhilashayadav8390]

Best ❤️❤️

[@official_52ji]

This is the best video , l ever seen on this topic

[@NonstopNeuron]

It took me a month to create it. 😅 I am happy that my hard work was worth it. Please share so that all can benefit from it. Thanks

[@manvithjoel8014]

Super

[@pritichaurasiya203]

Best

[@f.a.s3271]

Thank yuoooooooooooooooo

[@user-bx2no7ot1y]

10/10