This is a more in depth version of the skin cancer video on the Chubbyemu channel. I made this. That's me in the picture. That's me speaking. You can see it, you can hear it, I even pin this here, and someone's still going to miss it 😩
Your videos help progressively move our thinking forward. And by the end of listening to each one I actually do feel motivated to take care of myself and BE WELL! Thanks!
I am only saying this because I value your work and your channel, but... The pictures of your face don't contribute much to the video. I would almost have preferred that you linger on the other images if time does not allow you to edit in video of your narration.
I do not understand half of what you’re saying; however, I can’t stop watching. I absolutely love your content. If this were available 10 years ago my life may have turned out differently.
Happy to see this one get re-visited. The other video wasn't so clear as to why it's such a bad idea to remove suspected cancer on your own. That being the potential of cancer cells entering the blood stream.
Totally unrelated to the video but is your profile pic from the movie never ending story? Well it is... but like, yay, I haven't seen many people who know of it
The reason behind this is the idea of metastasis. Cancer cells can and will continue to grow within the confines of its growth site until it grows to a certain size where parts of it can chip off and enter the bloodstream. From there on, it can latch unto different secondary growth sites away from the primary one and start its growth again.
It is for some cancer depending on the type and how long you've had it. If it's early stage and not spread it gets cut off and that's it. But there are some that even if caught early are a death sentence. But a lot of people die because their cancer is found too late And already spread. However there are some cancers that can be spread and can still be cured. This melanoma is the skin cancer you don't want. For whatever reasons even cut out early this is the really bad one of the 3 skin cancers.
Even at 52, I still love learning new things. I write down and look up what I don't understand....and I had alot of writing and researching to do with this one.
@@icecream6256 Hi Ice Cream!!! I will be happy to share the resources I use. First of all, I do want to clarify that I do have good base- knowledge of the human body because many moons ago I used to be an LPN. So, I do have some A&P, and basic knowledge of some disease processes. That being said, back when I went to school, we were given a very basic overview of cancer, not nearly enough education to be oncology nurses ( the oncology nurses I know all have their RN’s). A couple of books that can help get you started are “Human Anatomy and Physiology” by John W Hole, and “The Human Body in Health and Disease” by Kevin T Patton and Gary A Thibodeau. You can get both books used, although the anatomy and physiology (A&P) will set you back a bit. Both books also come with study guides, which I recommend. Also, be sure to get the latest edition of each book, or as close as you can get to the latest edition, since information does change over time due to ongoing studies of diseases and treatments. The library can be a great source of information as well, though usually their giant textbooks can’t be checked out, but they are really interesting to read. I know there are also a lot of excellent online resources, but I am a “book” person. I love books I can use my highlighters in, ones that I can make notes in the margins and re-read, so I mainly do use books. I wish you luck and success on your lifelong journey of learning!! If you have any more questions, please feel free to ask.
The older video made me feel really uncomfortable and anxious about these types of cancer. This version with the outlook and developments in treatments left me with a better feeling. Great video as always! Thank you!
My wife has non small cell lung cancer. She has had one form of immune therapy, and it worked very well for about 6 months. She then had Keytruda. After a severe reaction to Keytruda, in which the immune therapy attacked healthy lug tissue, Keytruda was stopped. There has been no cancer progression since stopping Keytruda. Her medical team tells her that in cases such as hers, I.e., after a severe reaction to immune therapy, the cancer has been permanently halted. We are hoping that is the case. The histogram the gentleman with the tumor on his neck is striking. And his doctor had keen insight. I had no idea that immune therapy had been under consideration for so long. Thank you for the very thoughtful and interesting history, well presented.
The fact that you had to add an extra sentence in to say the 4G and 5G is not the same thing as Radiation Therapy makes me want to cry! Love the more in depth look into this topic. The slides must have taken an age to produce and I know what your face looks like when you say words, so a still image there is perfect!
I like how he's able to put information into a way we all understand I have learning disabilities but I find the way he does this really helps me understand more.
My grandfather had a tumor in his hand and the hospital said it would take months to operate, afraid it might spread by then, he went out to the shed and cut his own hand off with an axe, he ended up having leukemia.
I remeber an analogy I got of the function og TSGs and Oncogenes. They said that Oncogenes are like pressing the gas pedal on the cell cycle and mutated tumor supression genes are like removing the brakes from it.
Having known a lot of farmers, this type of thing doesn’t surprise me. I knew a farmer who used dead skin from his foot when he was fishing instead of some bread. You get a lot more crazy people in the farming industry for some reason
I had a mole my Dr wanted to cut off and when I asked if I could have a friend cut it out with a razor, she looked at me like I was insane! I guess this is why, glad I made the right decision to let a professional cut it out and test it!
Absolutely LOVE these deep dives into the cases already covered, it's like Chubbyemu videos with the training wheels taken off. Far more information for those capable of understanding it, and an even more enjoyable experience (for me, anyway) then the source video by far. I hope to see more and more of these!
@stephenseehorn7286 oh man that takes me back. I haven't watched numberphile in years. Probably since I was like 16. Math is a young man's game anyways haha
@@KingofCrusher I kinda get hyperbolic when drinking, so I was probably cup-shot when I posted this. No, they aren't super advanced, but you must admit there was much more going on in this video then the original, and I prefer this style.
@@KMStarner82 Ridiculous. If a company actually found a broad cure for cancer, they would make billions off of the sale almost overnight, and more in stock value. The problem is that cancer is not one thing. There are over 100 types of cancer, and while they all share the same concept of uncontrolled cell growth, they're all quite different in causes, mutations, physiology, etc. There likely won't be any one cure for such a category of highly complex diseases. But if Pfizer or whoever finds it, you bet your ass they're marketing it.
@@thelongestrose Exactly. They wouldn't make more money off of failed chemo. They'd make it from selling the cure and saving the person's life, thus allowing them to potentially get cancer over and over; selling them the same absurdly expensive cure each time.
There's so many different factors and mechanisms involved in keeping the human body alive, it's almost overwhelming to process. It's a wonder we don't all drop dead within the first day of birth.
One thing i was taught in nursing school that has never failed me... if a farmer presents to the emergency department, assume the absolute worst and that he could code at any minute until proven otherwise
For the record guys, NEVER cut (or otherwise attempt to treat} your own suspected cancers! If you do it, in any way except perfect, there's a real chance you will just cause major metastasis that's near always fatal!
@@zapazap It's not enough, all cells must removed, all at once, without leaving a single cell behind or in any way damaging the mass. It's why margins are considered so important during removal surgery. Technically, even needle biopsies have potential to cause catastrophic metastasis by puncturing the mass & allowing some cells to escape the main mass, developing the metastasis of secondary masses. Simply enough, burning is not remotely adequate, especially with the like of a cigarette. In surgery we do cauterize but that's with tools that get /stay extremely hot & stop bleeding, not to kill any cells. Just don't do it! There's pretty much never any legit reason for any to do so. Such cancers are usually slow acting & have really good outcomes with early treatment by professionals. Alternatively, trying to do it yourself is just likely to result in complete failure of the procedure, deadly infection, shock, blood loss, etc; all will kill infinitely faster then the cancer might have.
As someone with biology/biochem background, most science podcast are a bit to simplified for me, even your main channel videos are a bit too simple sometimes. I've always wanted something that was more in-depth, but where I didn't have to go and read the published papers myself. This channel was exactly what I was looking for. Absolutely fantastic way to tell this guy's story, with the perfect amount of background/review info. I'm not an MD, but these videos are like "medical clue" for me. 😂 Its fun to come up with a hypothesis as to why the initial event caused the disease.
Melanoma treatment has progressed dramatically since this unfortunate man's battle with it. Insulin resistance appears to promote the progression of many/most types of cancer. In other countries outside of the US they are experimenting with combining insulin suppression (strict zero carb diet with minimum/moderate protein) with "standard of care" therapies and hyperbaric oxygen to extend survival and in some rare cases completely eliminate the cancer cells from the host.
😆 I love how he just inserted the photo of himself in place of where he would have been shown narrating. That cracked me up. I love the unique sense of humor.
oh god this is the exact version of all your videos i've wanted i absolutely wish i'd found this channel sooner, the simplification takes all the actual interest out of it!
It truly is incredible that Dr. Bernard not only practices medicine professionally, but actually takes the time to create such high-caliber content. A chubbyemu video is like an entire episode of House, in less time, with more scientific/medical literacy & accuracy, AND with no love-triangles to speak of!! They're so in depth, well researched, palatable (that's coming from a layman) and even peer-reviewed in some cases; it's bonkers that this content is free! I've no doubt that your 2 channels and your professional career enhance each other, and that one makes you better at the other, so I would assume that's one of the many personal benefits of doing both. I, also, would not be surprised in the slightest if your videos were regularly viewed in medical classes, or at the least, by medical students. All that is to say, whatever compensation you receive for making this content, is not enough. You definitely deserve more for what you do. Seriously wish you all the best man. Thank you for making this content, thank you for being you, and I hope you achieve whatever heights you may be striving for, both as a Doctor, and as a top-tier content creator.
Wow, amazing and overwhelming details. Not a medical student here. I think it went through my ears. Yet I still like this new style of videos. Great work!!
This was one of the most interesting cases in the chubyemu channel... Happy to know it in detail.... Medical science will emerge more there is a lot yet to be discovered, learned and apply
This is such a complex topic and is pretty hard to follow for non-medical people like myself, but somehow I'm able to somewhat follow this narrative anyway. That's the sign of an excellent teacher.
I have one on my face that has been there for about 7 or 8 years. I had a biopsy about four years ago, and it was benign, but she said it could turn malignant. I don't know if that is true. The biopsy hurt so bad, I felt the razor, so I never went back to get it all cut out. The doctor has even called me to encourage me to come back and let them cut it out. It has grown more since they cut it for the biopsy. I haven't had the money to get it done. For some reason, I stumbled across this video. I suppose I need to call the doctor. This is more serious than I thought! Thank you so much for this information!
I could watch this over and over again. All these different mechanisms and pathways has my brain going to a lot of other possibilities. Wish I was born with a dialectic memory. Thank you for doing these videos.
This stuff is awesome. Comprehensive.. You have a great way of teaching that actually helps people to understand instead of memorizing all of it. Great pathophys. Wish you were my instructor in nursing college. 😄♥️
I like this better than the main channel. I'm not medical but my background is in molecular biology. I appreciate the informative discussion of the molecular factors in disease and in-depth discussion of metabolism.
I had a birthmark mole removed at thirteen that was just starting to turn cancerous. We got to it in time-it was starting to grow. I know it was a close call. I also know a teacher who died recently with melanoma.
Your way of explaining is elegant. Even though I’m uneducated in the topics you speak on, & rather unhealthy & 70~ I’m loving that I follow your stories with such interest. And little rewinding. Your choice of art and including many connections all clarify. Where you could get the story muddied if you did not, like so many, not love the topic- not have a past of so loving to know to take care of people, you have to have imagined (pictured) in your casual time all interactions. Chemical & Social. Your Joy is easy & phenomenal. Thank You. ❤
The transition at 23:08 really threw me off but ended up being a really nicely detailed way of tying immunotherapy and its origins into the subject...Very neat!
Here in scotland they dumped a load of radioactive painted dials from ww2 aeroplanes in the firth of forth and they washed up on a beech about a mile from the famous rail bridge
I have basically no idea what half of this stuff means. But I’ve often thought about stepping out of the engineer roles I’m into and learning to be a doctor instead - something useful. Especially with recent events. I dunno, maybe these a reason I’m an engineer - I don’t think my brain could handle being a doctor.
Do it, Moon! Who knows - maybe your experience as an engineer combined with training as a doctor could prove invaluable. You could invent or improve upon some of the technologies that are used to save lives! 🤘🏻
why not both? i'd be an interesting combination :D And maybe you'd solve problems faster because of the your perspective as an engineer, but applying the medical knowledge as a doctor
Wonder if insulin suppression (by dietary means) combined with glutamine blocker (DON 6-diazo-5-oxo-norleucine) could have possibly halted the cancer growth long enough to give him time to receive treatments. He presented so late in the progression, there was practically no time to even initiate treatments.
Unfortunately from the description of the primary melanoma he cut out it sounds like it was already highly differentiated (mutated from normal) and might well have metastasized before he ever cut it out. Once a melanoma metastasizes it's usually basically incurable, it's a very tough cancer. Treatment would probably have bought him some months, nothing more :(
Great channel. Side note: The “radium girls” were effected in the mouth and jaw because they used their lips and saliva to bring their tiny paint brushes to a point. (Also, note that it’s ionizing radiation, not ionized radiation.)
Trpv4 causes migration and metastasis in systemic and cns cells, as you noted particularly in the blood brain barrier. Heat from radiation stimulates trpv4 to activate the breaking of the intercellular bonds and conformational change of the cytoskeleton that allows the break in the endothelial monolayer and how cells migrate/metastasize from their tissue of origin.
This is a more in depth version of the skin cancer video on the Chubbyemu channel. I made this. That's me in the picture. That's me speaking. You can see it, you can hear it, I even pin this here, and someone's still going to miss it 😩
I see it🤣 Thanks for all your work. I’m sure you’ve saved many lives educating the public.
A Medical CZcamsr Pinned A Comment Of His On His Second Channel After Years. This Is What Happened To The Aforementioned Comment's Reply Thread
I love your videos, and you’re so handsome! Put that pic anywhere you want to 😂
@@ERSx4 I dont think he will like that
Your videos help progressively move our thinking forward. And by the end of listening to each one I actually do feel motivated to take care of myself and BE WELL! Thanks!
This dude just used a picture of his face everytime he talks instead of recording it. This level of efficiency is hilarious
Dr. Bernard's genius is beyond our comprehension.
Personally, I love it. Keeps my ADD in check since our brains are wired to pay attention to faces!
I could look at him all day. He's hot.
He's actually a practicing ventriloquist so this is a major compliment.
Yeah I was like: 👁👄👁
This is a more in depth version of the skin cancer video on the Chubbyemu channel. It’s not a reupload
Fantastic to get some more depth on that case. I learned a lot. Thanks!!
Thanks for the clarification, I knew it sounded familiar
Heme Review Podcast, ok
I am only saying this because I value your work and your channel, but... The pictures of your face don't contribute much to the video. I would almost have preferred that you linger on the other images if time does not allow you to edit in video of your narration.
We demand real-time video of you! What's with the cardboard cutout!? -sniffs-
It feels like the details of the main video was 480p and this video has 4k detail
Yeah
When you can't find a good clip so you just put your face
Jennifer Choi, hey hey
Not very good editing....
Tyler N, hey hey
At least he has a nice face! :)
That is a good thing
I do not understand half of what you’re saying; however, I can’t stop watching. I absolutely love your content. If this were available 10 years ago my life may have turned out differently.
this is how one learns
damn
You mean you wouldn't have drunk that snowglobe?🤣
Please elaborate
"Emia" - meaning presence in blood
Happy to see this one get re-visited.
The other video wasn't so clear as to why it's such a bad idea to remove suspected cancer on your own.
That being the potential of cancer cells entering the blood stream.
Totally unrelated to the video but is your profile pic from the movie never ending story? Well it is... but like, yay, I haven't seen many people who know of it
@@fanderping5515 Yes! Gotta spread the good word somehow!
The reason behind this is the idea of metastasis. Cancer cells can and will continue to grow within the confines of its growth site until it grows to a certain size where parts of it can chip off and enter the bloodstream. From there on, it can latch unto different secondary growth sites away from the primary one and start its growth again.
@@juwanbantug5465 would one be able to remove the origin fully somehow??
@@juwanbantug5465 All the while giving the host a false sense of security
that's how 8yo me thought cancer worked i-"just remove the bad part"
It is for some cancer depending on the type and how long you've had it. If it's early stage and not spread it gets cut off and that's it. But there are some that even if caught early are a death sentence. But a lot of people die because their cancer is found too late
And already spread. However there are some cancers that can be spread and can still be cured. This melanoma is the skin cancer you don't want. For whatever reasons even cut out early this is the really bad one of the 3 skin cancers.
you’re not wrong; it’s just that sometimes, removing the bad parts is more difficult that “cut off the bad parts you can see”
But doing it yourself how do you know the margins?
Even at 52, I still love learning new things. I write down and look up what I don't understand....and I had alot of writing and researching to do with this one.
Thank you! glad you learn from and enjoy, and super glad you look further into the topics!!
That's good. Research shows that learning new things is a good way to keep Dementia away, too. As well as being fun!
@@SkullPrism I totally agree!!!
Hey, im still relatively young, do you mind sharing how are you learning new things on your own ?, would be really grateful if you do
@@icecream6256 Hi Ice Cream!!! I will be happy to share the resources I use.
First of all, I do want to clarify that I do have good base- knowledge of the human body because many moons ago I used to be an LPN. So, I do have some A&P, and basic knowledge of some disease processes. That being said, back when I went to school, we were given a very basic overview of cancer, not nearly enough education to be oncology nurses ( the oncology nurses I know all have their RN’s).
A couple of books that can help get you started are “Human Anatomy and Physiology” by John W Hole, and “The Human Body in Health and Disease” by Kevin T Patton and Gary A Thibodeau.
You can get both books used, although the anatomy and physiology (A&P) will set you back a bit. Both books also come with study guides, which I recommend. Also, be sure to get the latest edition of each book, or as close as you can get to the latest edition, since information does change over time due to ongoing studies of diseases and treatments.
The library can be a great source of information as well, though usually their giant textbooks can’t be checked out, but they are really interesting to read.
I know there are also a lot of excellent online resources, but I am a “book” person. I love books I can use my highlighters in, ones that I can make notes in the margins and re-read, so I mainly do use books.
I wish you luck and success on your lifelong journey of learning!! If you have any more questions, please feel free to ask.
The older video made me feel really uncomfortable and anxious about these types of cancer. This version with the outlook and developments in treatments left me with a better feeling.
Great video as always! Thank you!
My wife has non small cell lung cancer. She has had one form of immune therapy, and it worked very well for about 6 months. She then had Keytruda. After a severe reaction to Keytruda, in which the immune therapy attacked healthy lug tissue, Keytruda was stopped. There has been no cancer progression since stopping Keytruda. Her medical team tells her that in cases such as hers, I.e., after a severe reaction to immune therapy, the cancer has been permanently halted. We are hoping that is the case.
The histogram the gentleman with the tumor on his neck is striking. And his doctor had keen insight. I had no idea that immune therapy had been under consideration for so long.
Thank you for the very thoughtful and interesting history, well presented.
Farmer:erases cancer on his skin
Cancer:you forgor my secret files
What an absolute mad lad, he put his face every 30 seconds or so
The fact that you had to add an extra sentence in to say the 4G and 5G is not the same thing as Radiation Therapy makes me want to cry! Love the more in depth look into this topic. The slides must have taken an age to produce and I know what your face looks like when you say words, so a still image there is perfect!
I like how he's able to put information into a way we all understand I have learning disabilities but I find the way he does this really helps me understand more.
It look like you have learning disabilities
You must be the most awesome prof! You make everything really understandable.
Right?!?!? Get this man some plastinated props and he’d make a killer anatomy channel, as well! ❤️
wish teachers didn't suck at teaching.
@@SigHellion you realize these arnt his vids lol
@@swagmullenix5458 you know I’m referring to @chubbyemu yeh?
@@SigHellion yes these aren't his videos it from another channel that has been around for a long time.
I really enjoy this long content.
I wish my college classes were this interesting 😪
My grandfather had a tumor in his hand and the hospital said it would take months to operate, afraid it might spread by then, he went out to the shed and cut his own hand off with an axe, he ended up having leukemia.
Oh no 😣
I remeber an analogy I got of the function og TSGs and Oncogenes. They said that Oncogenes are like pressing the gas pedal on the cell cycle and mutated tumor supression genes are like removing the brakes from it.
Having known a lot of farmers, this type of thing doesn’t surprise me.
I knew a farmer who used dead skin from his foot when he was fishing instead of some bread. You get a lot more crazy people in the farming industry for some reason
Chemicals prolly
This channel is just amazing!!!
hasan kharfan, it is the greatest channel.
I know heme review and chybemmenu are the best.
I had a mole my Dr wanted to cut off and when I asked if I could have a friend cut it out with a razor, she looked at me like I was insane! I guess this is why, glad I made the right decision to let a professional cut it out and test it!
Fine be afrsid:
I've heard ink from tattoos go in lymph nodes also...tattooed people need to be checked
@@kathleenking47 Is that true??? Both my brothers and my niece have many tattoos.
Heme review videos make me feel so much smarter than I actually am
"Ahh yes, BRAF"
Absolutely LOVE these deep dives into the cases already covered, it's like Chubbyemu videos with the training wheels taken off. Far more information for those capable of understanding it, and an even more enjoyable experience (for me, anyway) then the source video by far. I hope to see more and more of these!
These videos really aren't that advanced.
@@autodidacticartisan lol I know, the OP is talking like these are Numberphile vids or something.
@stephenseehorn7286 oh man that takes me back. I haven't watched numberphile in years. Probably since I was like 16. Math is a young man's game anyways haha
@@KingofCrusher I kinda get hyperbolic when drinking, so I was probably cup-shot when I posted this. No, they aren't super advanced, but you must admit there was much more going on in this video then the original, and I prefer this style.
@@exidy-yt lol dude me too, I don't know many THIS IS THE BEST THING EVAR comments I've left when I'm tipsy, hah.
Nice heme!
Thanks, I produce it myself.
As an oncology nurse now I understand better melanoma. Thank you
There’ll be a day that’ll change the world forever. The day someone finds the cure. Someday :/
CBD?
Forest Seaton CBD doesn’t cure cancer
They already have.
They just refuse to give it to us because they make way more money off of chemotherapy.
@@KMStarner82 Ridiculous. If a company actually found a broad cure for cancer, they would make billions off of the sale almost overnight, and more in stock value. The problem is that cancer is not one thing. There are over 100 types of cancer, and while they all share the same concept of uncontrolled cell growth, they're all quite different in causes, mutations, physiology, etc. There likely won't be any one cure for such a category of highly complex diseases. But if Pfizer or whoever finds it, you bet your ass they're marketing it.
@@thelongestrose Exactly. They wouldn't make more money off of failed chemo. They'd make it from selling the cure and saving the person's life, thus allowing them to potentially get cancer over and over; selling them the same absurdly expensive cure each time.
Holy crap, this is great. You should lecture at uni, I'd definitely pay to listen to you explain this stuff to me for a couple of hours.
There's so many different factors and mechanisms involved in keeping the human body alive, it's almost overwhelming to process. It's a wonder we don't all drop dead within the first day of birth.
God
@@jujutalleyThat’s deep 😨
Man, that comment just started the dreaded existential crisis in my mind.
One thing i was taught in nursing school that has never failed me... if a farmer presents to the emergency department, assume the absolute worst and that he could code at any minute until proven otherwise
Your channel is awesome. I’m in high school but trying to study as much medical stuff as I can. Your videos are really informative and interesting.
For the record guys, NEVER cut (or otherwise attempt to treat} your own suspected cancers!
If you do it, in any way except perfect, there's a real chance you will just cause major metastasis that's near always fatal!
I am not advising it, but wat about cauterization? E.g. with a burning cigarette?
@@zapazap
It's not enough, all cells must removed, all at once, without leaving a single cell behind or in any way damaging the mass. It's why margins are considered so important during removal surgery.
Technically, even needle biopsies have potential to cause catastrophic metastasis by puncturing the mass & allowing some cells to escape the main mass, developing the metastasis of secondary masses.
Simply enough, burning is not remotely adequate, especially with the like of a cigarette. In surgery we do cauterize but that's with tools that get /stay extremely hot & stop bleeding, not to kill any cells.
Just don't do it! There's pretty much never any legit reason for any to do so. Such cancers are usually slow acting & have really good outcomes with early treatment by professionals.
Alternatively, trying to do it yourself is just likely to result in complete failure of the procedure, deadly infection, shock, blood loss, etc; all will kill infinitely faster then the cancer might have.
Going into college next year, the level you explain at gives me a good challenge lol
Nicholas He, but why?
As someone with biology/biochem background, most science podcast are a bit to simplified for me, even your main channel videos are a bit too simple sometimes. I've always wanted something that was more in-depth, but where I didn't have to go and read the published papers myself.
This channel was exactly what I was looking for. Absolutely fantastic way to tell this guy's story, with the perfect amount of background/review info. I'm not an MD, but these videos are like "medical clue" for me. 😂 Its fun to come up with a hypothesis as to why the initial event caused the disease.
Melanoma treatment has progressed dramatically since this unfortunate man's battle with it. Insulin resistance appears to promote the progression of many/most types of cancer. In other countries outside of the US they are experimenting with combining insulin suppression (strict zero carb diet with minimum/moderate protein) with "standard of care" therapies and hyperbaric oxygen to extend survival and in some rare cases completely eliminate the cancer cells from the host.
Doesn't oxygen feed cancers,?
😆 I love how he just inserted the photo of himself in place of where he would have been shown narrating. That cracked me up. I love the unique sense of humor.
He is a doctor. Probably was too busy this time but at least he got the video made.
oh god this is the exact version of all your videos i've wanted i absolutely wish i'd found this channel sooner, the simplification takes all the actual interest out of it!
23:09 ooh two in one (honestly these in-depth episodes are awesome)
You’re the most incredible doctor I’ve ever watched on CZcams. You really know your stuff and give us hope for a healthy future and a cure for cancer.
I like the extra note that ionising radiation isn't that same as 4g 5g network
I love how you dive significantly deeper into the physiology in these videos
It truly is incredible that Dr. Bernard not only practices medicine professionally, but actually takes the time to create such high-caliber content.
A chubbyemu video is like an entire episode of House, in less time, with more scientific/medical literacy & accuracy, AND with no love-triangles to speak of!!
They're so in depth, well researched, palatable (that's coming from a layman) and even peer-reviewed in some cases; it's bonkers that this content is free!
I've no doubt that your 2 channels and your professional career enhance each other, and that one makes you better at the other, so I would assume that's one of the many personal benefits of doing both. I, also, would not be surprised in the slightest if your videos were regularly viewed in medical classes, or at the least, by medical students.
All that is to say, whatever compensation you receive for making this content, is not enough. You definitely deserve more for what you do. Seriously wish you all the best man. Thank you for making this content, thank you for being you, and I hope you achieve whatever heights you may be striving for, both as a Doctor, and as a top-tier content creator.
Wow, amazing and overwhelming details. Not a medical student here. I think it went through my ears. Yet I still like this new style of videos. Great work!!
This was perhaps your most thoroughly researched and presented topic. You have outdone yourself. So much useful information. Bless you..!!
Is this the detailed version of the previous chubbyemu video?
yes
Yes
Yes
Yes
Yes
This was one of the most interesting cases in the chubyemu channel... Happy to know it in detail....
Medical science will emerge more there is a lot yet to be discovered, learned and apply
Clear and informative. Most impressive, as usual. Thx so much!💖
As some one who wants to be an rn your videos are so helpful and interesting
NinjaNerd and MedCram are both also phenomenal
This is such a complex topic and is pretty hard to follow for non-medical people like myself, but somehow I'm able to somewhat follow this narrative anyway. That's the sign of an excellent teacher.
For non medical students I find putting on captions to be very helpful in keeping up with the explanation, especially if you're a really fast reader
I have one on my face that has been there for about 7 or 8 years. I had a biopsy about four years ago, and it was benign, but she said it could turn malignant. I don't know if that is true. The biopsy hurt so bad, I felt the razor, so I never went back to get it all cut out. The doctor has even called me to encourage me to come back and let them cut it out. It has grown more since they cut it for the biopsy. I haven't had the money to get it done. For some reason, I stumbled across this video. I suppose I need to call the doctor. This is more serious than I thought! Thank you so much for this information!
🙏🙏🙏
Hope the best
Yes dont let it go tooo long or it can e too late. Also when they cut it out you are probably not awake.
@@angieskidney Thank you. I am finally in the process of getting it taken care of.
I could watch this over and over again. All these different mechanisms and pathways has my brain going to a lot of other possibilities. Wish I was born with a dialectic memory. Thank you for doing these videos.
Thanks for the extra details!
I felt like your eyes were moving every time I looked slightly away from the video...
I’m a PA student and these videos are fantastic to work through difficult cases in my head! I love it!
This stuff is awesome. Comprehensive..
You have a great way of teaching that actually helps people to understand instead of memorizing all of it. Great pathophys. Wish you were my instructor in nursing college. 😄♥️
I like this better than the main channel. I'm not medical but my background is in molecular biology. I appreciate the informative discussion of the molecular factors in disease and in-depth discussion of metabolism.
Never mind my earlier post, it's a more in-depth version, highly recommended!
Noodles no. It’s a more in-depth version with info o had to cut out of the Chubbyemu video
@@HemeReview Just noticed, thanks for getting back to me! 👍
I had a birthmark mole removed at thirteen that was just starting to turn cancerous. We got to it in time-it was starting to grow. I know it was a close call. I also know a teacher who died recently with melanoma.
More please! really love your content
Thanks again Dr. for the knowledge.
I’m addicted to this channel and now am regretful I didn’t go into the medical field
Same man
Never too late - I started at 30.
Your way of explaining is elegant. Even though I’m uneducated in the topics you speak on, & rather unhealthy & 70~ I’m loving that I follow your stories with such interest. And little rewinding. Your choice of art and including many connections all clarify. Where you could get the story muddied if you did not, like so many, not love the topic- not have a past of so loving to know to take care of people, you have to have imagined (pictured) in your casual time all interactions. Chemical & Social. Your Joy is easy & phenomenal. Thank You. ❤
Very detailed. I love it. Great 🖼️.
The transition at 23:08 really threw me off but ended up being a really nicely detailed way of tying immunotherapy and its origins into the subject...Very neat!
The book 'Radium Girls' is incredible. I highly recommend it.
The whole part about RAD to ERK went completely over my head.
just can't get over the fact how well doom ost pairs with this video
Why is there a random picture of him
So we remember what he looks like
To endorse his handsomeness and his face.
Comic relief and quick way to confirm its "chubbyemu" creator
Possibly too busy with his job this time? At least the video still got out.
Thank You very much for this highly informative video.
Definitely read The Radium Girls - that book was amazing and enraging at the same time.
Love the still image of just you looking to the left
heme 👏 review 👏
i love these videos / podcasts!!
Cerys Skies, heme is better than meme.
I've seen his picture so much I feel like I know the guy and now consider him a friend🤜🤛
Enjoyed the deep dive on this and bonus points for using music from the DOOM (1993) video game!
Chubbyemu is simply a powerhouse of education :)
RAF, BRAF, RIFF RAFF. Some very important RAFs
oh my god dr. goku just mentioned PCR biology flashbaaaackksss
Is that Bird Stewart and Lightfoot’s transport phenomena at 14:42 ? Wasn’t expecting that 😂😂
Love the stock footage in this one!
I love learning about this, I just don’t want to be a doctor, lol great job!
Man, this is an upgrade to the original!
There are many kinds of RAF.
My favorite is the one that flies the Typhoon FGR4.
"You'll be proud of me" he said. He was wrong.
Great job ❤❤❤ 😊
Every time his pic pops up I can't help but laugh lmao. Like who does that?? 😂
Why the static image of you just looking wistfully off camera? 😂
Amazing video
i really enjoy watching this :p
Here in scotland they dumped a load of radioactive painted dials from ww2 aeroplanes in the firth of forth and they washed up on a beech about a mile from the famous rail bridge
I have basically no idea what half of this stuff means. But I’ve often thought about stepping out of the engineer roles I’m into and learning to be a doctor instead - something useful. Especially with recent events. I dunno, maybe these a reason I’m an engineer - I don’t think my brain could handle being a doctor.
Do it, Moon! Who knows - maybe your experience as an engineer combined with training as a doctor could prove invaluable. You could invent or improve upon some of the technologies that are used to save lives! 🤘🏻
why not both? i'd be an interesting combination :D
And maybe you'd solve problems faster because of the your perspective as an engineer, but applying the medical knowledge as a doctor
Well Bernard is both things!
Heme Review - Dr. Bernie videos with more details. Cool!
Chubbyemu rocks!
Wonder if insulin suppression (by dietary means) combined with glutamine blocker (DON 6-diazo-5-oxo-norleucine) could have possibly halted the cancer growth long enough to give him time to receive treatments. He presented so late in the progression, there was practically no time to even initiate treatments.
Unfortunately from the description of the primary melanoma he cut out it sounds like it was already highly differentiated (mutated from normal) and might well have metastasized before he ever cut it out. Once a melanoma metastasizes it's usually basically incurable, it's a very tough cancer. Treatment would probably have bought him some months, nothing more :(
can i get a still shot of chubbyemu smiling
Great channel. Side note: The “radium girls” were effected in the mouth and jaw because they used their lips and saliva to bring their tiny paint brushes to a point. (Also, note that it’s ionizing radiation, not ionized radiation.)
That can't be true, I've been assured by all the most reliable sources that women were not allowed to work before the mid 1980s.
4:29 you know he was so excited to use that big word
Trpv4 causes migration and metastasis in systemic and cns cells, as you noted particularly in the blood brain barrier. Heat from radiation stimulates trpv4 to activate the breaking of the intercellular bonds and conformational change of the cytoskeleton that allows the break in the endothelial monolayer and how cells migrate/metastasize from their tissue of origin.
"I definitely needed a big bandaid after this one" what a chad