The role of exercise in mitochondrial health.
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- čas přidán 5. 08. 2024
- In May 2020, we spoke with Dr Mark Tarnopolsky, Director of the Neuromuscular and Neurometabolic Clinic, McMaster University. Mitochondrial Disease is the most common neurometabolic disease that he sees at his clinic.
In this video, Dr. Tarnopolsky discusses how mitochondrial disease is diagnosed and why it is so challenging to make a mitochondrial disease diagnosis. He also explains how exercise benefits mitochondria.
Thats my doctor who diagnosed me with mitochondrial disease Leigh syndrome
Really
Hi am from Bangalore India I have MNGIE could you elaborate about exercise diet etc... please what treatment is going on now?
I had to have two biopsies to get my KSS diagnosed.
I suffer with tinnitus, am taking the online course Triumph over Tinnitus 3.0, and the creator, Liam Boehm, says the root cause is metabolic disorders and mitochondrial dysfunction, and the course testimonials attest to this. I've been doing the keto diet for some time alongside time restricted eating as recommended in the course, as well as other things. I have just joined a gym - which types of exercise are best for healing mitochondrial dysfunction - HIIT?
The interviewer microphone is much louder than the person being interviewed. There is a need to adjust the volume.
Is it best to exercise in the fasted state? Can drinking tea/coffee before exercise help?
Hi Jay
1. To improve your aerobic capacity, mitochondria and overall health, the main thing is obviously to get the 150-300 min of aerobic exercise in per week (whether you fast or not). Pending your level (novice vs expert), aim to keep your heartrate > 60-90% of your max heartrate (220-age BPM) for 30 minutes or more per day. High-intensity aerobic exercise is most effective but may not be suitable for patient populations or those with heart disease; thus, consult with your family doctor first. 2. There is some scientific evidence that caloric restriction is beneficial for health/longevity and obviously short-term weight management, but long-term sustainability is an issue and fasting is not ideal from a high-performance perspective (glycogen loading for example). So no, overall, I would not recommend fasting before high-performance or physically demanding tasks. Eating more than a snack/preworkout supplement is not recommended either, however. 3. Caffeine and other 'active compounds' in green tea and coffee (for example catechins/polyphenols) have some performance, cognitive, and weight loss benefits. Caffeine & polyphenols act as antioxidants and may certainly work as browning agents/mitochondrial enhancers in white adipose tissue. So yes, you may consume coffee as a preworkout stimulant and may see some benefits. Everything in moderation, though. If you are interested in the effects on acute fasting and/or polyphenol intake on mitochondrial biogenesis, I will refer you to the following search engine as a start (pubmed.ncbi.nlm.nih.gov/?term=intermittent+fasting+aerobic+exercise). Cheers, Mats
@@matsinilsson9578 Thanks for the extend reply and link. There is a treasure trove of info there.
No problems! Good luck. 👍
Chris Farley used to do this skit on Saturday Night live where he was a horrible TV host and was very awkward asking his guests questions. It feels like this guy is copying that skit. Was it really that hard to say the word " cellular"?