circular dichroism

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  • čas přidán 5. 09. 2024
  • This video aims to describe the basic mechanism of Circular Dichroism and how it could be used to predict changes in protein secondary structure

Komentáře • 75

  • @xcherubbie
    @xcherubbie Před 4 lety +7

    My professor was so confusing when he explained CD! Your video was so clear and concise, thank you so much! :)

  • @andresbertoni848
    @andresbertoni848 Před 6 lety +3

    Excellent video. Really concise, very well diagramated and full of key information (applications included). Kudos!

  • @monikakannan7
    @monikakannan7 Před 25 dny +1

    Clockwise direction is RCP and anticlock wise is LCP sir.

  • @azx4591
    @azx4591 Před 8 lety +3

    thank you so much for this!! my lecturer completely confused me and you put it so nicely

  • @ryancxx
    @ryancxx Před 6 lety +2

    Great video, this is the best video about CD on youtube

  • @priyasekar86
    @priyasekar86 Před 7 lety +1

    Thank you so much for explaining this in the most simplest way

  • @buhtan5693
    @buhtan5693 Před 5 lety +2

    Thank you for explaining clerly about CD spectroscopy

  • @neetisingh2825
    @neetisingh2825 Před 4 lety +1

    The best part about ur videos is that they are very concise 👍

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 4 lety +1

      I am launching high yield flash card for quick revision before exam day.... subscribe to my other channel for thatczcams.com/channels/4IpyopsGWSjaPACNTZLuqg.html

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 4 lety +1

      All cards are time lapse and 30 s with no audio .... you have to look at the motion graphics and say the audio by yourself to revise.... if you like those intactive content please share among your friends

    • @neetisingh2825
      @neetisingh2825 Před 4 lety

      @@animatedbiologywitharpan sure sir😊

  • @user-fm1yt5cr7d
    @user-fm1yt5cr7d Před 8 lety +7

    Congratulations for your explanation. Very clean!!! Please, make more videos!!! : ) Cheers from Brazil!!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 8 lety

      +PRO GAMING BRASIL
      Thanks . You could also suggest me topics on which i can make new videos.

  • @quickbiology5159
    @quickbiology5159 Před 2 lety +1

    Awsome Arpan ,you are amazing

  • @subratadas9271
    @subratadas9271 Před 5 lety +1

    Next week is my exam, I get the best idea about this from this video.. Thanks a lot 😊

  • @arabindu1
    @arabindu1 Před 5 lety +4

    tmrw is exam n m getting the easy explanation struggling from 3 month. lots of thanks.

  • @Secessionist
    @Secessionist Před 2 lety +1

    Good explanation

  • @ericdzenis2786
    @ericdzenis2786 Před 5 lety +3

    I wish you had talked more about the differences between the protein conformations.

  • @kaileighm.obrycki9297
    @kaileighm.obrycki9297 Před 7 lety +4

    This video helped me so much, thank you!

  • @AtulKaushal7
    @AtulKaushal7 Před 5 lety +5

    Very good explanation. Thank you.
    A small correction: You missed the curly brackets there.
    Al - Ar = (El - Er)lc
    dA = dE.lc

  • @DeepikaChoubey
    @DeepikaChoubey Před 7 lety +4

    +Arpan Parichcha this spectra should strongly depend on the composition of the protein then how these generalised curves can be drawn for helices and sheets? does it take amino acid propensity into consideration? if yes, can you provide reference?(I'll look up too though)

  • @Zeyfer0s
    @Zeyfer0s Před 8 lety +1

    Thanks, nice introduction to CD, reminded me a lot :).
    (got there a tiny mistake in the equation with absorption coeficients of R and L - missing brackets, but I really don't mind)

  • @shahinghamari2720
    @shahinghamari2720 Před 3 lety +1

    thank you it was great

  • @sristi_2360
    @sristi_2360 Před 2 lety +4

    CD Was nver this clear to me. Also do you have lectures on other biophysical techniques like uv visible and fluroscence spec? Actually I have some doubts & can't find them in your channel. Your channel is always my last resort whenever I am stuck with any concept 😭

  • @bikrammajhi7278
    @bikrammajhi7278 Před 3 lety +1

    Thank you!

  • @kalyanreddy6229
    @kalyanreddy6229 Před 6 lety +1

    Very easy to understand thank you

  • @user-bw9bn5mb2z
    @user-bw9bn5mb2z Před 6 lety +2

    Thanks it's very method easy

  • @kathleensicinski563
    @kathleensicinski563 Před 6 lety +1

    Great explanation!

  • @Chazmaster23
    @Chazmaster23 Před 6 lety +1

    Really helpful!!! THANKS

  • @sancharidatta1014
    @sancharidatta1014 Před 5 lety +1

    Thank u sooo much sir for giving a complete concept about this topic...thanks a lot...

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 5 lety +1

      Glad to hear that you found it useful......share in your collge group and help me to reach a big audience

  • @srikantsahoo5975
    @srikantsahoo5975 Před 5 lety +1

    Sir please make video on Optical rotatory dispersion, cotton effect

  • @vigneshs5286
    @vigneshs5286 Před 3 lety +1

    Tq sir plzz suggest some good books for spectroscopy as well as mcq book

  • @garyhamilton1981
    @garyhamilton1981 Před 6 lety +1

    Thank you very much

  • @shubhamb.deshmukh7920
    @shubhamb.deshmukh7920 Před 7 lety

    Great job man! Thanks :)

  • @SoReaICru
    @SoReaICru Před 7 lety +1

    Hi Arpan,
    I was wondering about when you drew the 3 curves of the CD Spectrum why the alpha helix curve looks like how you drew it, why the beta strands look like how you drew it and the random coils too.
    If I was given a CD spectrum of my own, I assume I can predict the secondary structure by comparing it to how closely it follows the 3 curves you have drawn, but I wanted to know the underlying principle. Thanks

  • @besamwansa8802
    @besamwansa8802 Před 8 lety

    Superb!! Thanks

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 8 lety

      thanks Besa...If you have any suggested topics on which i can make video please let me know

  • @kunukandayashodha2166
    @kunukandayashodha2166 Před 6 lety +1

    what about enantiomeric peptides

  • @sarahn3935
    @sarahn3935 Před 6 lety +1

    Hi, Can you write the step or the explanation for circular dichroism in the comments?​

  • @galaxy_of_adu.
    @galaxy_of_adu. Před 5 lety

    Nice presentation

  • @wafakendil3963
    @wafakendil3963 Před 5 lety

    very helpful thank you !

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 5 lety

      Glad you found it useful...if possible share my channel link in your community such that I can reach bigger audience

  • @stevejobs5
    @stevejobs5 Před 6 lety

    Best video ever

  • @saravanarajm5330
    @saravanarajm5330 Před 8 lety +1

    nice video. .hope ur points help me for my semester after 2 two days. .may I know how is ORD(optical rotary dispersion) related to this circular dichroism..???reply soon as possible

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 8 lety +2

      +saravanaraj m
      concepts of ORD and CD are quite similar(but they have a fine line of difference) i would say both are manifestation of same underlying phenomenon.
      spectropolarimeter is based on the principles of ORD .It measures ability of an optically active compound to rotate polarized light as a function of wavelength(one could think it as wavelength dependence of optical rotation).ORD is about the way the material refracts polarized light in a different way, when the wavelength of that light is changed. ORD is measured as the difference in absorption or extent of interaction with the incoming light, when wavelength of the light is changed. ORD is usually used with plane-polarized light, and the change in optical activity is tracked as wavelength is varied. As we saw with CD, ORD examines the wavelength effects of linearly polarized light incoming upon the material, and looks at how much the recorded CD is being changed as different wavelengths are used. Short wavelengths tend to interact more strongly with materials, compared to longer wavelengths, so we experiment with different wavelengths to do an ORD spectrum. What we get out of an ORD spectrum is the difference in transmission speed of left- and right-circularly polarized light going through the material.
      The way CD and ORD operate is built in such a way that the two methods can provide information about each other. With ORD associated with dispersion and CD connected with absorption, it is possible to use Fourier transforms to convert between these two.
      If the ORD spectrum shows a positive tendency, then long wavelengths of the polarized light are interacting more strongly with the material, creating a positive CD band. If the ORD spectrum goes in the opposite way, this means a negative CD band, and short wavelengths of polarized light are interacting more with the material.

    • @saravanarajm5330
      @saravanarajm5330 Před 8 lety

      thank you

    • @princessprincee3265
      @princessprincee3265 Před 6 lety

      Arpan Parichha thanku

  • @alisadeq5705
    @alisadeq5705 Před 7 lety +1

    What is PEM

  • @mujeebkhan8150
    @mujeebkhan8150 Před 7 lety +1

    plz Hindi video prsent send

  • @srikanthp2649
    @srikanthp2649 Před 5 lety

    dog sound

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  Před 5 lety

      Focus on the content ....Hopefully you might find it helpful

    • @srikanthp2649
      @srikanthp2649 Před 5 lety

      can u make new video on d techniques that are used in determination of an unknown pathway