9. Gluconeogenesis from lactate, glycerol, propionyl coA and glucogenic amino acids
Vložit
- čas přidán 14. 12. 2018
- Gluconeogenesis
Synthesis of glucose from non carbohydrates precursors
Precursors/ substrates includes
1. Lactate
2. Glycerol
3. Propionyl coA
4. Glucogenic amino acids
Not exactly reversal of glycolysis
3 irreversible steps in glycolysis reversed by 4 important enzymes
1. Pyruvate carboxylase
2. Phosphoenolpyruvate carboxykinase
3. Fructose 1,6 bisphosphatase
4. Glucose 6 phosphatase
Gluconeogenesis
Site - cytosol/ mitochondria
Mostly in Liver and to some extent in renal cortex
1. Important source of glucose during starvation after depletion of glycogen ( after 18 hrs)
2. Important source of energy for brain and RBCs
Energy utilized - 6 ATP/ glucose synthesis
Regulation
1. Induction and repression
Insulin represses pyruvate carboxylase
Glucagon induces
2. Covalent modifications
By phosphorylation and dephosphorylation of enzymes by hormones
Glucagon phosphorylate enzymes and activates
3. Allosteric activation
By acetyl coA
And inhibition by F2,6 BP
My god i got some hopes of passing in my Biochemistry exams ... ur explanation is very interesting
Good
Did you pass
@@architsingh572 😂😂😂
@@161divyanshsharma4 gandd faati paddi hai bro..don't laugh😂
@@architsingh572 muhs se hi hai kya?? Best luck kal k liy🥶🥶 main bhi aaj hi video dekh rha bhai..same haal hai😂
I wonder how good our country's education would have been if all the teachers taught like you.
Thanks a lot sir !
Keep it up!
,❤️
No words to express.... before watching ur videos, i had phobia of this subject but now this has become my fav subject.... tqsm
Sir I'm never interested in biochemistry until I find your YT lecture. Now I really understand the concepts and found out it's really an interesting subject.Now it's part of my Favourite subject. Thankyou so much Sir. You truly inspire me🙏🙏🙏
Thanks for feedback
same with me
Same
Saviour for students who study at last moment.
Sir you are just awesome. Far better and lucid explanation. Learnt in 20 minutes. Hope to see your channel expanding.
I have downloaded all of your metabolism videos from CZcams on my phone and saved offline . Your way of teaching is very simple yet understandable. Thank you sir 🙏
Thanks a lot sir for simplifying the whole pathway....I feel a lot more confident after watching your videos🙏
Guys pray for me . Aj mra bhi biochemistry ka paper ha aik lufz bhi ni atta . Plz pray for me
Bhai pass hue kya?
I love Dr Rajesh ...apki wja sy Meri biochemistry Bht achi hai ...or easy b lgti Hain
..I'm from Pakistan ... Alot of respect from Pakistan sir
Thank You
I learned more from your videos than I did from all my education in United States in college. thank you
Thank you so much sir
I never found any lecture as like yours
U r Simplifying all my hard ones
Thank you sir for your amazing lecture before watching this lecture I used to think that I will not be getting any interest in biochemistry but your lecture gives hope. Thank u sir now I think that I can pass in biochemistry.
U r superb ..I use to hate biochemistry..but now I m loving it
Thank u so much Sir for such a beautiful explanation of each and every topic
आपको सादर धन्यवाद ,
आपके ही दिए हुए ज्ञान से सच में ऐसा महसूस होता है की हा सच में हमे जो चाहिए वह मिल गया।
आप जिस प्रकार समय निकालकर यह कार्य हम बच्चो के लिए किया उसके लिए आपको अनंत धन्यवाद।
यू ही हम सब की इस प्रकार मदद करते रहिएगा।
🙏🙏🙏
Because of u sir I did not find biochemistry a hard subject,Thanks alot Sir
Wonderful explanation! Thank you Sir !
Thanks so much sir, I really enjoy d lesson, may God continues to increase you in knowledge
Amazing and really helpful ...maza aa gya biochemistry padhke dhanyawad sir
Thank you sir, it helped alooot!!
May God bless you!
Great explanation and fairly concise.
Brief and crisp explaination ...👍👍
Thanks a lot sir
Thanks sir for such a wonderful lecture class, hope this support will go on
Literally... incomparable.. explaination...✨
Helpful I read two books u made me more clear thank u sir
Thank u so so so much....sir.. I am going through ur notes and videos..I am going to rock in biochem..u made it simple
Thanks a lot sir..
It will help us in University exams..great effort sir🙏🙏
JUST WOW
bole toh yaha sab concepts milega wala feel aa gya sir
THANKYOU SO MUCH
great teaching sir! concept cleared:-)
Sir Your explanation was fabulous , logical and easy .
Heartly thanks you sir 👍👏
Allah apko khush raky yar app boht achy tarikey se samjahty haii.
In some hours i have biochemistry's exam please pray for ny inocent soul 😂😔
You are my favourite biochemistry teacher 😄 from CZcams
Thank you so much sir...amazing explanation...keep it up... kindly make more videos...thanks a lot sir👍👍👍
Very nice explanation....thank you very much sir for your efforts...😊😊
Thank you, sir. Such a savior 🤗
Thank u very much 4 such hard work Sir.
Sir this video is just amazing ...it helped me a lot lot....thanks sir for making it ....your videos are helping me a lot in first year biochemistry of my MBBS course
Thank you.
Thanku so much sir you saved by life really best tutor ever
Thanks allot ,, great service , Stay blessed 😇
Now understood gluconeogenesis properly🙏.thnx sir
Thank you sir for your simple lectures,👍
Thank you sir ji for your great explanation 🙏
Thank you so much sir, because of u only I was able to get good mark in biochemistry of my University exam
Quite understandable..my doubts got sorted.. ThAnku sir
thankyou sir....you made bioc very easy and interesting one.. keep going on sir..
Simply amazing. Keep it up sir
Bundles of thankx, Sir U are Amazing God Gifted for Us
All are crystal clear... thank you so much sir...
Very helpful video sir 👌to the point explaination.
Such an amazing explanation thanku sir❤️
Thnk u sir u give me reasons for reading biochem ❤️I will pass in my professional MBBS exam
Isssss... Helaa aau
Sir can You please add videos in playlists by adding numbers with sequence so that we can start a playlist... Regards Sir 🙏
Thank you so much 🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻your way of explanation , way of writing points are more helpful to understand well..👍👍🙏🏻thanks again..!
Thanks a lot Dr. R.Jambhulkar sir
Thankyou sir for such clear explanation 🙏
Damn good class, highly recommended, thank you sir for your effort
Short & sweet ways of learning biochemistry ❤❤
Thank u
Never stop teaching ❤️❤️❤️ more power to you ❤️❤️❤️❤️
Can't thanks enough for such beneficial videos of biochemistry ☺️☺️🙂
In love with ur teaching sir ❤
Awesome video
Thanks a lot sir 👍👍
You r just amazing sir ..❣️
Wow, this is awesome
Super lectures. thank you sir❤️❤️❤️
Thank you sir.
It really helped me alot 🥰🥰
Really, sir I'm not getting to tell, ur a great sir
lot of thanks sir for biochemistry and all dreams comes truely in your life🙏🙏🙏🙏👍👍👍
🙏🙏
Thank you so much sir
May god bless u like how u blessed me with this incredible video
❤️🤧❤️
Brilliant work👌👌just bcz of uh i started studying bchem
U r really my saviour today tq sir
Sir plzz continue making vdios ....also upload 4th sem lectures plzz ,ur art of teaching is amazing ...plzz continue
Thnk u so much sir this video helped me a lot sir
Wow your way to explain the topic is amazing keep it up sir love from pakistan
Sir your lectures are really helpful 😁😁
Thank you sir keep up the great work..
Thanku sooo much sir for this kind of mind refreshing explanation😊
Thku sir ur class is very helpfull... for me 🙏🙏
Thank u sir keep uploading!
Thank you sir very much u r the best
Sir your lectures are very beneficial to me ❤️❤️❤️
You are god for us for biochemistry 🎉
Good teaching sir
Explanation is very easy way
Simply Amazing Sir..
Thank you
Sir jo pyruvate hai usko oxalo acetate mai direct convert krne ki kya zarurat h ham jo normal kreb cycle h uska oxaloacetate se bhi toh phosphoenolpyruvate Bana skte h
Very good explanation 👏👏👍
Thanku sir... for teaching so well...
Could u make a video for glucose alanine cycle too
Very helpful that too in short period of time and detailed also...Hatsoff to you sir..Keep on making such videos sir, U are really impacting students like us who are in dire need of clearing concept in short period of time.🙏🙏🙏👍👍
Great piece of work sir
Thanku sir... It is soooooo helpful...
Sir may Allah full fill ur desires and wishes vry interesting teaching 🤲🤲🤲🤲🤲🤲🤲❤️❤️❤️❤️❤️
Bhut accha parhaya sir...👌👌👌👌
Excellent 👌keep it up sir 👍🏻
Real class feeling in virtual learning 😇👌 Amazing explanation!!!
Sir its very helpfull😇 sir am an Msc botany student, even its very benefited for me, great job sir, god bless you sir
💕from Kerala
Extremely excellent.....
THANK YOU SIR..NICE CLASS😊
Bahot badhiya guru ❤️
Thank you so much sir🙏