The Infamous Drug Trial That Shocked Britain | Real Stories Full-Length Medical Documentary
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- čas přidán 10. 04. 2018
- On Monday 13 March 2006, eight healthy young men took part in a clinical trial of an experimental drug known as TGN1412. The drug was intended to treat leukaemia and had already been successfully tested on monkeys but never on humans.
It should have been a routine clinical trial but it soon spiralled into one of the most infamous medical emergencies in recent British history.
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It’s truly strange watching British documentaries as an American. American documentaries are so loud with constant motion and nonstop drama. I appreciate watching something that takes its time to tell the story without the need for embellishment.
I mean this was quite intense too.
August Break Same
It isn't that it's British. They just didn't really need to be flashy because of the content... People fighting for their lives... pretty hardcore as is
L L there’s a balance that a lot of documentaries and reality shows strike. This one hits right on the mark.
August Break omg ikr!
Patient “am I going to die?”
Doctor “the real question is am I going to prison?”
@Kimber 10MM wtf are you talking about
@Kimber 10MM don't you understand it's just a joke , if you don't understand, Okey let me tell you it's a human thing & you need to settle up in a zoo
That’s funny
😆
It's an experimental drug, he volunteered.
I have been receiving a type of monoclonal antibody infusion every 4 weeks for the last 10 years to treat an autoimmune disease. This medication saved my life and allows me to continue surviving. The people who are willing to submit themselves to clinical trials like this are part of the reason I’m still alive, and I have so much respect for them.
True but 😅😅😅😅
My son has a number of symptoms that are autoimmune in nature rendering him at 35 unable to work and using a cane but some days unable to leave the bed. He has been given possible bur never firm diagnosis for everything from MS to Parkinsons to Meneirs to heavy metal intoxication as he shows signs of all. One of the neurologists who seemed most hopeful finding neuropathy and all the signs of his own immune system attacking his digestive and nervous systoms suggested a drug to him which was described as a chemo drug originally for cancer patients but has shown to aid patients such as he. God i wish we coyld speak to you to somehow find out if you have a similar set of issues. If so much comfort it would be while making this very important and heart wrenching decision
I also have an autoimmune disease. I am taking Telfast and Montelukast daily. If I stop, my throat gets tight and itches all over the body. I live with misery and doctors couldn't help me.
There probably not so happy
Maybe try prolonged water only fast around 10 days? Prolonged fast is the only thing that treats and cure autoimmune diseases. And then carnivore diet.
I'm being treated for ovarian cancer. I cannot express my gratitude to the people who have risked their life to try to save mine
I can’t imagine being the person who received the fake medicine, and having to sit there, listening to all this wondering if you are next.
Wait I don't get this where do they say that they were given the fake drug?
two people recieve something completely else while the others recieve the drugs. But no one knows who got what but the doctor/nurse. i believe its explained in the beginning of the video.
neither the docs nor the nurses knew, only the one who packaged them.
at 8:03
ah thats right, thanks.
me: oh man my knees hurt again
*watches documentary *
never mind i’m good
Joji Jo I love it 😂
Same
legit me
@@becky2322DM me, you look stunning :)
LMAO
It is glanced over so quickly that Ryan lost his finger tips and got a part of his toes and foot amputated. Wow my heart goes out for him ♥️.
Considering he has sadly passed, I think this was the least of his problems. This entire trial was absolutely horrifically botched, whether by accident, on purpose, the medication simply didn’t work or otherwise
@@JoyfulNerd400 He died??!!
When? As a result of this trial?
@@BlackKiryuu he did end up passing away, yeah. His organs failed and as far as I’m aware his treatment failed in the end
@@JoyfulNerd400 Oh my God. I feel soo sorry for him!
Did his family get any help after his death? Like compensation for damage and what not?
@@JoyfulNerd400 Bullshit. A fast Google search leads to a Facebook post from January 2021 saying that Ryan "recently graduated with a First in BSc Economic & Social Policy", and from there one can find a "Birkbeck Events Blog" that states that in 2012 he had a son, in 2016 he started his part-time BSc Economic and Social Policy degree, and that in November (2020) he graduated, winning the prize for the best final year Economics and Social Policy student. Also, judging by you saying "the medication simply didn’t work" and "his treatment failed in the end", you don't even understand what a drug trial is (none of the volunteers needed the drug!). Please avoid saying ignorant and stupid things, everyone reading your comments could end being dumber as a result.
I found this a very interesting article. My granddaughter had a rare cancer at the age of 2 and ALL of her treatment was through international clinical trials. Part of her treatment was immunotherapy, where one of the risks was a cytokine storm because of the use of monoclonal antibodies. After nearly four years of treatment she is now five years in remission. The harsh treatments she had have left her with a variety of health problems, but she is a happy 10 year old now and very precious to our family. Whilst she has contributed to many clinical trials through her treatments, we are indebted to the children who have gone before her and may have since died of the illness or the treatment. Anyone who contributes to the advance of medicine through participating in clinical trials (of whatever stage) is making a massive contribution to the rest of humanity.
Amen. I agree. And with any trials, all precautions should be taken, and there should ALWAYS be an ESTABLISHED anecdotal plan in case of known, and especially unknown, side affects.
The posh doctor interviews between creepypasta-like reenactment scenes is such a mood
@@pamsam8933 I I IC think ⁹I 99
@@pamsam8933 the problem is that you can't know the side effects to 100% certainty in advance. You can inject them into mice and monkeys and test on human cells and determine it "might" be safe. When you are the one taking a drug that no human has taken before, nobody can predict with certainty what is going to happen, it's a big risk and they should (and almost always do) tell you that it is a risk.
The reason things like this are big stories is because of how rare events like this are. The vast, vast majority of first for human clinical trials have the worst problem of people withdrawing due to side effects. This occurs in both the cohort getting the drug and the cohort getting placebo. Multiple fatalities in a single trial is so unusual as to lead to videos like this. The risk is higher in rare illness, where there just fundamentally isn't as much data in. Even then, like in this case, actual death is exceptionally rare.
Everyone else:
*screaming in pain*
That one dude:
*mom come pick me up im scared*
mmm
That guy would be me
@Saint Beelzebub 😭😭😭
「 Cinderblock 」 😂
Hahahahs
I've got to stop reading comments while watching documentaries. The amount of times I have to rewind is absurd.
into the mystic comment section is better than the vid
@@ethank5681 there would be no comments without the video
Keep doing the same lmao
thanks for the reminder, i wouldve gone 10 minutes deeper without this comment
I was thinking the same... lol
This is astounding. I'm 24 years in remission from Leukaemia and two years of gruelling chemotherapy treatment I endured from 16 - 18. I imagine at some point each one of the toxins in the specific chemo cocktail I received were one trialled by participants equally as brave as these hero's. And I can say I wouldn't have envied what they put themselves through in doing so either! But I'm beyond grateful they did! Even given the long term ramifications I'll be dealing with from here on in, I wouldn't forsake that for the experience I had knowing what it is to be in love and the pure joy I eventually experienced in giving birth to two gorgeous and extremely precious daughters.
It's crazy when you think about the fact that healthy people took chemotherapy drugs first to see if it was safe. Knowingly taking the equivalent of a bomb going off in your system since it'll destroy everything in sight is wild
Success stories like you are exactly why I work in research. Every single cancer therapy and Alzheimer’s drug trial I hope not so see any observations or toxicity. It is always very sad when something doesn’t work as intended.
Not brave but stupid. Usually people in need of money.
Your life is worth so much more than money!
No to pharma.
Congrats to you, and I hope you live to see 103 😊
Totally irrelevant, but the dramatization of this event was first class. As a cancer survivor, I am so grateful to anyone who participates in trials. Including the medical staff who take part. I am sorry that these men went through this horrific experience and I am grateful that, despite the dire consequences, new protocols relating to trials have been adopted. Seeing David with his young family was a huge relief ❤️
My twin sister nearly died from Covid. The dramatization in this show is similar to what she went through. People next to her who did not make it were wheeled away. She said it was the worst experience of her life. Thank God she survived.
@@sylviaking8866 oh my goodness, how traumatic for her. I hope she is fully recovered now.
There's not enough money to be made giving you a cancer wonder drug. Probably been around hidden for years. Pharmaceutical is a business. It's all about money not your good health.
Part 1: company brings patients to trial. Part 2: patients bring company to trial.
If only it was that easy
And loose!
AppleYou Brilliant comment!
I'm sure the patients signed away any probability of liability
Uno reverse card
Get this casting director a raise. All these actors look so much like the real people while also being able to actually act
I swear some of them are the actual people. Number 2 was definitely the same guy.
It’s epic bro
Best I’ve seen
Robert Gardea im aware what a re-enactment is... hence why I said props to casting director
StrawberryNinja Nibbles #mansplaining at its worst-🙄🙄
StrawberryNinja Nibbles omg you’re right. Without thinking about it, I unconsciously found myself thinking, how did they have video of these people when it was happening Lolol duh
I wish we could have had Ryan in the interview. I completely understand that he wouldn’t want to since he went through so much. I just wish we could understand what his life was afterwards.
He probably can't due to settling litigation out of court.
I wouldn't want my life broadcasted online either... but I wish him the best
ryan died actually
@@tshs1663 according to who?? Simple google search says absolutely nothing about him dying. He nearly died during his 4 months in hospital but he is very much alive after this horrific experience
@@tshs1663 source? I googled it, but couldn't find anything regarding him dying.
'It had been successfully tested on monkeys'... Those poor animals cannot say that they are in pain. The whole farmaceutic scam disgusts me.
Doctor: How we doing David?
David: Screams with agony and discomfort
Me when my mom wakes me up for school
flamingwolfgaming 101 disrspectful but true
Ikr
@@old-yd2kp
My bad
Doctor : seams ok to me
Everybody’s screaming in pain and the other dude’s just sitting there
He’s soooo lucky 🍀!
@@Timeless80 Haha, I was about to say that.
i would’ve hated to be him. imagine everyone around you screaming in pain... terrifying
@@dangerousbuterax6891 i'd rather be him than the ones that actually took the drug
@@LF-lv4ov same he's lucky
I can't help crying for Ryan. What a life for a young man..
What about the victims in the world's largest and latest drug trial? 😉💉
@@user-kz4ke8mg4r F-off. Its just not relevant to the comment and makes your point weaker by just making you seem like a troll. I assume thats the point tho right?
@@lynningram4218 don't tell me to F off - it's totally relevant. The 91DIVOC jab was A TRIAL. Wake up. 🐑
@@lynningram4218 you f off. And wake up.🐑
While nobody deserves the outcome of this particular medical trial, it’s an incredibly brave and selfless act to anyone who needs medicine and even to the lives that are forced into trials like animals. It’s scary but to think of all of the lives and families this event has saved. I’m so sorry to everyone involved but the gratitude I have for such people is incredible.
I'm sure they instantly regretted it lol
It makes me mad to think that the medication was administered 10 mins apart, rather than 90 mins apart. This could have only been one.
'Berto O. A. you never know if another person will react the same way to the medication if only one person got the trial. that’s why there’s usually more than one person getting tested
They just wanted to know who got the placebo.
@@birthdayplant it was never appropriately thought out and therefore that was negligence in a big way.
niyah and yet they all reacted the same way
niyah yeah and If it went that bad on one person then they wouldn’t do it on another however if one person was fine
I still remember how my 6th year biology teacher warned us to never volunteer to be a guinea pig. Thank you sir.
See, I'm thankful I study chemistry, not biology or medicine. I can watch them do trials from another building, thanks.
Honey Bee 😂😂😂 that's a great teacher
I had a science teacher start our origins, universe life etc with: don’t believe everything they tell you, remember many think a supreme being, god, caused creation, others do not... in any case we don’t know how or why the universe came into being let alone having physics perfect for star formation, nuclear reactions, time, matter, all of it. That said... shall we begin.... first there was nothing, then there was a universe... any questions? Right... ok.. and we opened our books to chapter one. The Big Bang. Haha and the lesson commenced. I thought he was clever and wise and he was a great teacher. He also gave us real experiments, not cheesy ones. More dangerous chemicals and dissection, less baking soda and vinegar. Haha... break out the scalpels and Bunson burners baby.. whoops. Bang. Teacher my test tube is no more! You ok? Yeah. Had your eye wear on? Yeah. Ok... do it again but this time don’t skip step three in the directions... sorry Mr. Moss. Haha he was cool.
The FDA also recommends not being the first to take new drugs; I'd suspect only people desperate for money (poor/poverty) would/will volunteer.
@@renees1021 I don't think they normally end this badly due to prior testing on animals but yea this is also a very plausible outcome.
In the last few years I’ve discovered just how much doctors don’t know what they’re doing.
💯
Makes sense considering that they did not build humans and have to learn what humans are made of and how each organ plays a role in order to know how to treat each organ
@@lebohangm7252 well, I wish they didn’t use my body to experiment with. I’m done with western medicine with several exceptions.
"I was really down... the worst down" - That's such a chilling phrase.
This reenactment is SO WELL DONE. Holy crap.
Ikr!! I had to go back to the beginning of the video to find where it said it was reenactment I was like damnn
They found actors who look incredibly like the real people involved.
Yes. I totally forgot that it wasn´t real while watching … :D
Susan Foley are all of them actors? I straight up thought one of them (the placebo guy watching everything go down) was the actual person
You believe this? They gave clinical trial medication, as a test...to humans with nothing to actually cure.. it was meant to cure leukemia....which these random people did not have
everyone: throwing up, screaming
that one dude sitting: alright ima head out
Megan Khadka it’s like... i didn’t know that
He was a control/ placebo
When was that? Just so I can skip a sis is scared of sick
B lasagna
anna commanda what does that mean?
I was in labor with my first baby and the pain was absolutely horrible. My husband said that I tried to get out of bed and leave. I truly believed that if I could just leave the room that I would be pain free.
Wording is a bit off
I tried this too. 😂 Funny now but at the time I was in so much pain and I was so scared. I told my husband I just needed to get out of the room and out of the hospital then I'd be ok. He was compassionate but also amused and said something like "but what about the baby? If you leave you still have to give birth." 😂 I don't know, man.
What honestly surprised me is that it seems like the people running the trails didn't have a plan for if things go horribly wrong.
They do now. And you must remember, nothing like this had ever happened before, during all the decades of drug trials. And this drug had already been tested on animals, with no adverse effects, at much higher doses.
Also these trials were preformed in presence of medical staff but even with that you cannot predict what immediate and also longterm side effects can occur.
The worst part was how quickly they dosed everyone. They first guy is in a cold sweat and writhing in pain, and while this is going on they are dosing the guys in the other room.
Julian Bell Mark R what was this drug trial for ?
what the heck was the drug trial for because all those people were 100% healthy and had nothing to cure ,
So do you think , is it really a cure they were looking for
or is it a way to make people sick to cut down the population , the government plan ?
They should have waited way longer for each person getting injected and they should have given a way smaller dose to check how they reacted to it
@@kristie-leecorney7388 lol
@@kristie-leecorney7388 can see that you didn't watch the documentary, so you'll come up with ingenious conspiracy theories. Get out.
Kristie-lee Corney This isn’t a conspiracy video. If the government wanted to cut down on the population they wouldn’t have tested the drug, they would have given it to the patient so they could die.
Everyone: puking, screaming, dying
That one guy: okay think imma head out ✌️
@Jimo National ok boomer
@Jimo National ok snow roach
@Jimo National and this is a problem because...
@@harssamoanlal2947 kip
@Jimo National apespeak isn’t a real word either 💀 what a mong
I'm surprised that they didn't have more doctors overseeing this trial considering how fast it all went sideways. You think they would be more prepared for that with it considering it was an experimental drug trial
Oh, you'd be surprised how low the requirements for trials are.... I wish I didn't know as much as I've learned in the last 5 years. One can only hope to have the luck of being and staying healthy.
The NIH didn’t even know they were doing this trial until the hospital called for help!
I was once in the hospital for some testing and they tried me on a new medication. I instantly had a bad reaction and the whole situation was super traumatic and to this day I am afraid to try new meds. Lot of the first symptoms these men described I went though but no where near as bad. I was in the hospital afterwards for almost 2 week and it took me almost 4 months to fully recover. This breaks my heart.
I once had an anaphylactic reaction to an antibiotic, now I’m terrified of taking any medication. I have a lot of allergies and I’ve had reactions to multiple different meds, but that was the scariest. Trauma is not something to take lightly, it can be debilitating.
When I was sick with rather severe tonsillitis, I've had Doumox (amoxiciline) administered and got a terrible rash all over my body in some 24 hours after first dose. It scared my GP so much she got our national drug administration involved and it eventually sparked a Europe wide investigation by EMA on the drug (mainly because rash was not on the list of known side effects at the time). My rash got better in like a week and I eventually recovered from the tonsillitis just to be completely astonished by all the internetional fuss I caused. I still have amoxiciline allergy written in big red letters on my folder in the GP's pacient registry to this day...
For those of you making fun of the doctor for asking if they're okay, it's actually a very good practice. First of all, he's making sure they're still responsive. Second of all, he's trying to keep them calm. If you saw someone crack their skull open, you wouldn't start shouting "OMG ARE YOU OKAY!? OH MY GOD HE'S GONNA DIE THAT'S A LOT OF BLOOD" no, you'd say "It's going to be okay, you'll be fine."
Just so you know
lmao some doctor (well, nurse) screamed "OH MY GOD THAT'S A LOT OF BLOOD!!!" when I threw it up once, thought I was gonna die
Index III is OUT my point exactly
Raven Ryder I don’t know why Parexel claimed to have no knowledge of their responses, but the pharma doctor read in the literature supplied by Parexel that their reactions were thought to happen rarely.
*aRe YoU oKaY*
(OMG YOUR DEAD i mean) its fine ur gonna be okay:)
Who else watched this, and immediately decided to never participate in a clinical trial? 🤯🧐
I heard about this at the time it happened and then decided the same. Your life and health isn't worth playing Russian roulette with. Even if nothing like this happens to you, you don't know what unknown long term effects might be caused.
Sarah Vela I have participated In one! Nothing happened to me thank goodness lol
Where did you participate in your study at ?
@Poppy Mystique I'm in a study right now in the states at a place called PRA Health Sciences in Lenexa, Kansas City, Kansas
My study right now is 5 days for $3,000 us
I had considered cosmetic trials, but after this there is no amount of money in the world that could make me want to participate. Just to risky for me.
Can we take a moment and acknowledge how horrible it is that we must subject animals (macaques in this case) routinely to these horrible experiments, and after a life of horrendous isolation and suffering, these animals are simply discarded like garbage.
So what are they suppose to do to help people then give them a solution then
Yeah it's horrible but there's no other way.
Our lives aren't above animal lives.
Look up Dr hadwin / Animal free research charity it is possible
I agree. I watch the TV show about Monkey World in Dorset, UK (on CZcams under Beyond Wildlife) where many of the primates came from laboratories and now get to live their lives at the sanctuary with other primates, the right food and the ability to go outside, play, etc. I noticed that the monkeys which appeared in the documentary were squirrel monkeys, but the narratives mention macaques.
Poor guys i hope they have managed to deal with the PTSD from this event. This is not something you can get over easily.
Agreed.
I don't blame them from being very weary about man made medicine.
"No one's gonna die right?"
"Well, we'll see"
well at least he was honest
That part made me laugh so hard
"We'll see... Well... I'mean I will see. In case you, ... you know."
followed by evil cartoon villain cackle lol
yeah doctors cannot affirm things they don't know or they might be charged with lies
Omg. Kid was 19 and saving up for driving lessons and now he has no fingers
Gavin Haase 47:09
He lost all his toes and parts of fingers. The tips
He can still drive. My mother had crippling arthritis, and could not hold the steering wheel, just guide it with her palms, and turned with her elbows. He only lost the tips. Not the whole fingers. Yes, it is a tragedy he suffered. So did my mother. She still made do. Reiterate, he CAN still drive.
I mean he could still drive? But they didnt specifically say what exactly happen to ryan..
@@nickhiggins1091 doesn't sound safe at all. That's why in your driving test you have two hands on the wheel. Not your elbows
Truly appreciate learning from this documentary more about drug trials and the way it was presented. Real Stories is certainly a favorite production company of mine when it comes to documentary filmmaking❤
It's insane that they didn't stop the dosing when they saw that it was going so wrong.
I'm sure they thought that the drug would be safe and effective
I think they gave the whole dose at once, fast, which was a mistake on their part!! It was too late to stop, as I understood it!
@@lenitaa7938 no they gave the drug with a perfusor which is slowly pumping the drug
They talk about how a lot of the man got back to “normal” but still one guy lost just fingers and a foot and his life was never the same
You should also watch the thalidomide documentary on youtube. czcams.com/video/6uizvsiaHyw/video.html
Not a one of them went back to normal, their immune systems are fouled up to this day.
Yeah I wanna know more about Ryan.
And his penis. So there’s that. Pretty significant if you ask me.
@@BS-dq1kz is that true?what a shame & he was the youngest of the group, not that it would suck any less happening to any of the others.
They all must have some form of PTSD from going through that
With a phobia of medication, needles and that i suppose
Well they nearly died that's pretty traumatic in itself
Yea thats for sure
Well then, they now should be advocates for banning all animal testing since they know the horrors.. but they had it WAAAY better than the animals that are still being tortured
Taunja Brockway but if animal testing had happend it would be different
Thank you for posting ❤
This is probably why clinical trials span a few months rather than a few days
Those 2 men won a LOTTERY called PLACEBO
precious lol
@@sunandmoon139 That's not actually what it is. It's when a person experiences a decrease in symptom severity, because they believe they are receiving medication. The placebo effect does not cure illnesses, it just helps to relieve symptoms.
@@sunandmoon139 It has to do with believing that you are receiving a treatment that will make you feel better. I reccomend that you look up some examples and/or articles about it on google, as it's actually quite fascinating. There is also the nocebo effect, which is when a person believes a treatment will have negative side effects, so they end up experiencing those side effects simply because they expected to experience them. There have been trials done where one group of people is give sugar pills (though the trial participants were told it was real medication) and were not warned of any potential side effects, while the second group received the same placebo pills, but were told a list of potential side effects they might experience. The people in the second group reported experiencing those side effects at a much higher rate than people in the first group. By believing they might feel unwell, the trial participants actually caused themselves to feel sick. It really goes to show how much your mindset can effect you. This even manifests psychologically as well.
For example, if you believe that you won't ever succeed, chances are you will have a lessened ability to perform tasks, low motivation, and little dedication. One of the biggest effects would be that you stop trying, and that you never actually put 100% into something. I mean, why bother putting your all into something if you are sure you will fail?? Alternatively, if you believe that you could be very successful, you would likely take way more opportunities, work harder and put more effort into things, have high motivation, and be very dedicated. These changes in behaivor have a serious effect on your life, and could actually cause someone to fail at things simply because they are convinced they aren't capable of succeeding.
This is called fortune telling in psychology, if I remember correctly. I'm very guilty of doing this myself, actually. It's harder than it sounds to let go of all the negative beliefs one has about themselves and start believing in themselves all of the sudden. It's really hard, and at this point I actually fortune tell about fortune telling. I know that I do it a lot, so I end up doing it even more simply because I expect myself to. It's maddening 😂😭
@@sunandmoon139 it has nothing to do with religion if that's what you're asking, although those words can be used in a spiritual context. if that's not what you meant ignore me haha
Comment war
I noticed they never talked about the eighth man, I looked him up and he’s wheel chair bound and had his fingertips fall off too.
How unfortunate for all of them.
Wow
Thank you for looking that up for us all!
what did you look up to find it?
Nicole Slaughter ...It mentions what happens to him right there in the video.
any link or name of the man so i could search it pls :) its very scary docu really if i could i would wish for this to never happen :(
Imagine how animals feel daily being tested on.
Animal testing is cruel too!! At least humans volunteer animals have NO CHOICE!!!
This should be a Netflix documentary
It should be that would be amazing
This could be on House MD or the good doctor
It’s better on CZcams.
Nah, CZcams's where it's at.
There is a indie style horror movie made based on this, wouldn’t recommend it.
Placebo guy: reading his book
Guy next to him: in horrible pain
Placebo guy: *chuckles I’m in danger*
Ralph wigam
Had this been done on animals, they would have suffered more intensely because they can't speak and tell you what they are feeling.
So sad. Kills me to think about
It was done on animals before the human trials. The animals didn't have this kind of reaction
@@MachallaNaNaNawell, not the last batch before it went to human trials. To establish dosage, they would have kept pushing it higher until they elicited negative side responses to determine the maximum. That also informs them of what potential side effects and reactions they can expect. Unfortunately, many animals would have suffered to get to the human trials stage, not to mention all the ones that had such horrendous reactions that it never reached human trials. And even if they didn’t suffer direct side effects from the drug itself, they would have been caged and poked and prodded, with multiple blood extractions and perhaps biopsies as well as some animals euthanised in order to open them up to see the histological changes to their bodies as a result of the substance. They wouldn’t have been kept in humane habitats.
It’s a huge problem with how we develop an understanding of disease and treatments. I don’t have the answers but I am well aware of the price of our health on other animals.
I have a close relative who has to take anti leukemia drugs, I am very thankful to those absolutely healthy people who take such risks and help the science to create safe medications
Doctors not care about their patients
@@edwardtrezza8129 if doctors don't care about their patients then how come they try their hardest to save their patients? But yes there are some bad doctors out there don't get me wrong, being a doctor is not for the weak.
@edwardtrezza8129
Huh? You making a blanket statement like that leads me to believe you're an ignorant fool.
That moment when you realize only three of the eight people are in the documentary ...
Nononoooo
That... no
I am fairly sure they all survived, though someone can correct me if I’m wrong. More likely, they couldn’t get in contact with the others, or they weren’t interested.
Lawsuits, NDA agreements.
Yes very strange. I wonder how the boy is doing who lost his fingertips and a few of his toes
ME, thinking I'm going to only watch 5 minutes of this and end up watching the whole thing!
Sammmme girl
This really does intrigue me .
God Is So Merciful .. Amen .
No amount of $$$$$ ... Is worth playing the , maybe , or , maybe not day !!! Which is a memory of , I'm alive !
Same! 😬
“We felt like we were guinea pigs” my brother in christ that’s exactly what you signed up for like?? I understand this must have been terrifying and felt so sorry for them but why are they talking like they were there without their consent, injected in a deceiving way and upset about the doctors that didn’t know what was happening and what was exactly wrong, that’s an experimental drug they don’t know what can happen that’s why they make trial tests in animals and then on humans.
You're point is right. However they didn't sign up to have MORE drugs being infected than just the trial drug. Yes it was to save them but they didn't know exactly if it will work. Pumping more meds in them to see what will work IS being a guinea pig
Kinda strange that they didn't immediately put them on dialysis...
Doctor: How are we doing, David?
David: *screams into the 5th dimension*
heiress of stupidity more like weirdly cut moans
I was thinking the same thing. The patient is clearly in distress and a great deal of it!!
lmfao best comment
Valincia Pruitt They ask anyways to make sure you can respond. Yeah you aren’t doing good but are you responsive?
That's what I thought.
This is like watching a horror movie but every detail actually happened
Ikr, it makes it WAYYY scarier... obviously
@@LiterallyEly honestly this scared me more than any horror movie ever has
Chilling documentary. Very well done.
Thank you for sharing.
David: literally dying
The doctor: yooo what's good david
😂😂😂 truly
i laughed too loudly at this
What is organ failer
My husband's face swell up like this...allergic reaction to dye in hair color
For all yall who do this kind of testing. Thankyou so so much. With out the test ....wow....
"there is no rulebook for such a case" makes me shiver
You are a true inspiration to all….we tend to complain about a lot of petty things but your story truly awakens the senses to what’s important….so happy you got through it with the help of your wonderful family.
patients: puking, fainting, screaming in pain
doctors: *Don't stop administrating the drug*
Mhm
😥
doctors: its working its working..infuse more drug
Ahhhh, the benefits of knowing more in the name of science
Ya what's that?
His fingertips fell off!! They weren't even amputated! Imagine just laying there watching your fingertips FALL OFF!!! I feel so bad for those men...
@jorge rodi Ohhhhh I'm dumbbbb
I got so freaked out!!
Bruh
@jorge rodi please use your inside voice
Necrosis is the term for Dying tissue. This is why I think this was blood poisoning. Necrosis can occur when the blood isn't healthy enough to provide the flesh nutrition, and the cells in the tissue die.
@jorge rodi Capital letters means you're shouting. So low your voice 🤗 and be caring.
They knew about the headache and pain and still injected the last patients. It's hard to comprehend.
These poor guys were thrashing around, probably thinking they were going to die and no one had the common sense to put the side rails up????? WEIRD!!!! I know no one expected all of this to happen! And God knows we need to produce life saving medications but I really did feel for these young men! And I'm sure the staff was in great mental anguish watching them suffer and not really knowing how it was going to end. But, as an RN of 31 years, the first thing I would have done was put up the side rails as a very simple measure of protection for the volunteers.
Imagine being one of the ones that got the medicine and being right behind the guy showing the first symptoms. That would be terrifying. He starts screaming and you have to wait until it happens to you. Talk about a horror movie.
😩
I'd rip the IV out b4 it was my turn. Not worth 2k.
@@ryanblack3285 apart of the 2k, you would get in a lot of legal trouble, you signed a contract. also by the time the first severe symtphoms showed up, the drug was already administered on everybody.
documentary: shows up in my recommended
me: aight ok guess i’m staying up another hour
claudia There is no sleep when there is CZcams 😆
It is nice when the algorithm works.
Me rn
claudia same!!
claudia 4:42 here
I’d be freaking out as soon as the first guy started to have some severe effects. Omg…
Very interesting! Thanks for this story 🙂
My first Chemo infusion took over 13 hours to complete. These men were given a full infusion in 10 minutes...That is crazy!
How are you doing? I hope you are doing well. I sincerely mean that.
@@sabitrakhadka8397 wtf is wrong with you
@@gg-sc6gy 1st time internetting?
@@kungfreddie yeah i made it 29 years and never once did I discover it until today
@@sabitrakhadka8397 swedish
Patient: No one is going to die right?
Doctor: Who's your favorite Avenger? Just wondering..
Patient: I prefer DC
Doctor: yeah im just gonna give you another dose
😂😂
I don't feel so good doctor
I like how these reply’s are taking the joke in so many different ways
HA
I absolutely love a doco and I have to say this is one of the best I’ve ever seen. Absolutely terrifying experience for those involved but the changes to drug trials since have meant nothing like this should ever happen again 💗
I'm sorry for what these men went through, but I am also grateful for them, they made it safer for those that were brave enough to come after them to also take part in clinical trials
I found it interesting that they didn't accept women because it was considered too risky.
While I can appreciate the chivalry it does aparently lead to mis-dosing for women because they don't test stuff enough on women.
@@HisameArtwork it’s also an immune system stimulating drug isn’t it? Women have stronger immune systems in some senses then men so it’s more risky to do first in human testing on women. Don’t think they often worry about it once it passes first in humans as it often moves to treating the people with the actual diseases soon after and someone with cancer is probably not as worried about side effects if it saves them.
@HisameArtwork
Its because "average" is considered an around 160 lb 5'11 male to drug companies at the time this study took place.
Its better now, people of different genders, sizes and genetic backgrounds take part.
This is the second time I watched this video, what a horrific trial these wonderful men went through, my daughter was diagnosed with leukemia at age 10 with other complications. Without brave people like these, my daughter would not be a alive today. This Was back in 2001. My sarah is doing well today. My only child. I owe it to brave people like the ones in this document. Thank you so very much from the bottom of my heart. Thank you. Mike, from Richmond, Virginia
That's great. But everyone that I know that had leukemia and was treated for it , died. They spent years of their life receiving agonizing treatment that was meant to save them, costing thousands. They would be in remission, like they were cured, then it returned, only to kill them quickly, since their immune system was gone. RIP: Aunt Marty, Steele, Carmen.
@@lorinagosso While that is the norm, there are a few exceptions. Perhaps her young age aided her recovery. Then again they say 25% of cancers get cured all by itself (not sure if it applies to leukemia though), but I guess most don't wanna play with those odds and go for the chemo route, despite it perhaps only buying them more time and only making their early death even more likely.
@@lorinagosso leukemia in a certain group age and the type of leukemia the person has determines the rates of their survival. Simply put the older you are the deadlier it gets, children have higher survival rates and longer remission. Sorry for your loss though, seeing a loved one succumb to illness makes you feel hopeless and it's a wound that never heals even after they pass.
I’m so happy for you and Sarah. I hope she loves a long successful life!
Hi Michael the world also won a precious gift then : Sarah. Please send her a hug all the way from Brasil !! She isa brave and inspiring girl ❤️🙏🏻
CZcams, I don’t think an add for a drug trial study is the best thing to run during this video. Like seriously, I don’t think people will want to take part in a study after watching this.
Pilar Tromacek 😂😂😂😂😂
2 months later and I got the add too!
ye THIS TOTALLY HAPPENED...
Yea CZcams has no humanity or morality left. Google is probably run by Skynet
XD still gonna, because someone got to be the one to do it
This is why I don't do trials. I did one and I had the symptoms of malaria. Never again.
The actor who played as the Doctor really had me stressed out as well, he did a great job. Everyone did
The saddest patient death I've ever dealt with was a man who had an unexpected allergic reaction to a psoriasis medication we were testing. He was a healthy guy in his early 50s. No one had any reason to believe he wouldn't be going home to his family the next day with some Christmas shopping money in his pocket. It was really a huge shock to everyone, especially his wife and kids.
I wish I wouldn't have read this.. Now I'm sad....I could only imagine how the wife and kids felt..
That is something you should understand taking any drug, isn't it? Let alone the one that was never tested on humans, no one knows whether it is safe and that's exactly the risk they are paid for.. If it was safe (and none of the drugs are just cause of the personal reactions anyway) there wouldn't be a need in testing it..
The people are lured by money like the 50 years old man that sadly lost his life. When you are 50 YO with family of your own, it’s not advised to take a trial test. Unfortunately he probably needed the money.
This is the devils medicine now learn natural medicine.
Just him? its a lot worse than you think be hind closed doors .
an hour long, slow-pace documentary, totally for free on youtube! this makes me very happy
Yus
ᴴᵃᶰˢ ᴮˡᵃᵃᵘʷ me tooo
There is hundreds of them on here they r amazing
What CZcams was really made for
I'm a former nurse and i remember hearing about this at the time. As i remember it they essentially gave all the patients the drug basically ask at once
Praying for wisdom and guidance for future trials. Well done documentary.
I cant imagine being one of the people with the placebo... just watching and listening to everythung around you, always wondering if youre next and when its going to happen. It sounds so terrifying...
Yeah and he was so young at the time so it really pulls at your heart for the poor boy.
American roulette
@Addicted 2This but also guilty though. Survivors guilt
Nah. after they were the onlyone in the room it didn't happen to, Im guessing they figured out they had the placebo. But the first hour or so would've been rough, yea.
I would feel so very guilty honestly
That one guy just sitting there on the bed was horrified.
I feel terrible knowing the mass pain they were going through.
m3m3d_ I felt real sorry for him . He was just siting there and every one else was reacting to it. He was probably thinking that he was going to get it soon
I would feel guilty for Being tho One Who got the placebo
crumch
Are you him (Looking at your profile pic even though I know it's just Arin
the 2 (one in each room) who got the placebo will definately have long term mental issues from what they saw and heard..I hope they both got some great counseling...crap like that can mess your head up for life.
As a healthcare professional that works in a hospital, this is an absolute nightmare all the way around. Everyone lost in this one
Once I took some medicine to treat heavy allergy, the name is Xyzall. I never felt so horrible, I became deaf for 1 week, had nose bleeding and I was paralyzed for 8 hours. I can’t imagine some people went though the medical trial with that crap, and why it is not discontinued. That was a very scary experience.
Did you check the articles they most likely published? Were all the side effects you had mentioned? Or are you aware of any other trials they did after yours? Having a trial doesn't automatically mean that the drug is put in a short term on the market. There might be a need for the drug or the method of administration to be changed... One needs a trial to find out how exactly a drug works on people and if and what is wrong...
@@potocatepetlno no no don't you see? It took some allergy medicine so he's an expert in pharmacology and clinical trials.
Best re-inactments I've ever seen. Usually SOOO cheezy
Dana Ashlie British do it better
@natalie L Same but that's mostly because I am British.
Dana Ashlie i agree plus the faces are quite identical too. i didnt realized it was just reenactment for the first 10 mins lol
I honestly though it was actual footage
So true !
It's crazy to think that they didn't have an emergency protocol in place. That doctor was scrambling to find any other doctor.
That dr was probably just a pawn on a larger chess board.
You can't plan for unexpected reactions
Very poorly administered trial for sure. Why inject them all at once??? Pathetic!!!
@@nasramohamed no he called for the other doctors because he didn't know what to do.
They don't know what to be prepared for, that's why they're called drug trials.
Unfortunately, too many people are still willing to inject untested drugs into their bodies with pharmaceutical companies having immunity from all outcomes
They tested a drug for leukemia on people that were in perfect health? How would this help, wouldn't it make better sense to test on people with the illness to see how it performs?, did I skip over a part..
I met a guy in London in 1996 who lost all his hair from drug trials. Even then I couldn't believe any one would volunteer for this
Did anyone else get an ad for a company looking for medical testing subjects during this video? I couldn’t stop laughing when I saw that ad...worst use of a product placement algorithm ever lol
yes, it was about 10min to the end of the video.(P.S I laughed too don't feel bad)
i got leggings ads like 5 times not kidding
That's priceless
that would be funny but scary at the same time
i did..and I thought the same..i was also thinking maybe a lawyer ad would have been better!
The placebo boys can count their lucky stars
Vehicle/control gang.
Black people can count their lucky stars….not 1 Black person experimented on.👊🏾
@@yamindapage1963 what does that have to do with anything? Further more that isn’t true 😂
@@yamindapage1963 🙄
I knew a guy in our 20s who signed up for clinical drug trials all the time for cash - never did anything else for a living. He also never wore anything but pajamas and flip flops.
I feel so bad for all the patients involved. It had to be terrifying not knowing what is happening to you or possibly going to happen due to the placebo. I hope they all received mental care for their well being. You all are courageous. We salute you for your efforts to help people get healthier. Thank you.
As someone with auto immune disease its heros like this that risk their lives that give me the medicine I need to survive.
If this would have happened in America, they would have been stuck with the medical bill as well.
@@Tyler-zw4kq just because a law suit is won doesn't mean they ever see the money
big facts. good ole american health“care.”
Lol accurate
@AL Cats They absolutely would have. It's the American way. Oh and when you write a sentence calling people stupid, make sure it isn't two sentences crammed into one.
@AL Cats I don't know . you tell us. How do you.
Honestly , I'll have more appreciation the next time I open medication .
In so far as possible, it is recommended that you avoid all medications. Beware the white coats.
@Sammy Slaughter I do hope despite the disease you and your son still find many amazing things to smile and be thankful for. May your 2020 be greater.
Odonnol
if only I could. I don’t want to be manic and suicidal again. Have you been there? So dark you fantasize about finally feeling and seeing nothing, never existing again. Hearing voices. But the meds finally started to work and now I’m feeling so much better.
@@hankanderson8633 Manic and suicidal, no. Glad you are finding relief. I had good luck with Western medicine for about 65 years, then got prescribed something that gave me an adverse reaction. I survived, but I am now much more cautious.
I don’t want then money anymore 😂😂😂
Excellent documentary
Wow, great story! I've never before heard of this event.
the 2 people who got injected with the placebo where so lucky
How hard is it to know the word “were” exists?
Maddie Trafford that was 2 months ago and people make mistakes
@@maddietrafford1225 oh get a life
DaisyV. Wolf хаха какво се случва
eh not exactly they probably have survivors guilt