I also think so but I am not sure as I do not have an experiance. However isnt it logic that smallest are oscilating fastest (they are first able to oscilate do the edges of trap while increasing RF) → thus they are able to leave the trap first. Then bigger and bigger. If we want to send biggest or medium first (with certain RF)→ would it not be the case, that all smaller would leave with medium/big too? (and it would not be what we expected, it would create bias) ... so I would say that it should be used only from smallest to biggest (while sending them f.e. to 2. analyser of MS/MS) .... or this is the different ability of QIT in contrast to IT ?
@@marianradvansky6304 I've once researched this and found Feynman transformation. Every particle oscilate in a specific way so type of oscillating is a thing abour characterization, based on this feature they're using Feynman transformation to identify that ion. It was something like this, I hope I could understand and explain well. I saw this on a orbitrap explanation.
I hope this video was helpful! Let me know what you think and in case you have any questions, please ask them in the comments!
Can't we make resonance with that small ion we interested? Wouldn't it be much more easier to make resonance on what we are interested in?
I also think so but I am not sure as I do not have an experiance. However isnt it logic that smallest are oscilating fastest (they are first able to oscilate do the edges of trap while increasing RF) → thus they are able to leave the trap first. Then bigger and bigger. If we want to send biggest or medium first (with certain RF)→ would it not be the case, that all smaller would leave with medium/big too? (and it would not be what we expected, it would create bias) ... so I would say that it should be used only from smallest to biggest (while sending them f.e. to 2. analyser of MS/MS) .... or this is the different ability of QIT in contrast to IT ?
@@marianradvansky6304 I've once researched this and found Feynman transformation. Every particle oscilate in a specific way so type of oscillating is a thing abour characterization, based on this feature they're using Feynman transformation to identify that ion. It was something like this, I hope I could understand and explain well. I saw this on a orbitrap explanation.