Systemic Amyloidosis on abdominal fat pad biopsy with Congo red stain (pathology dermatopathology)

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This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
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[@mariashafique9702]

Thank you Dr Jerad.

[@anson.meadows]

Have you ever interpreted salivary gland, looking for Amyloid Or immune activation?
Having trouble understanding the following:
“patchy plasma cell infiltrates (highlighted by CD138) are seen, and there is focal acinar atrophy with dense fibrosis”

[@yinyang2385]

Hi,
I am writing to esteemed experts in the field of dermatology with the hope of identifying a specialist interested in a unique patient case. The patient presents with an extraordinary medical condition, unlike any previously documented. They are experiencing trans-epidermal elimination of various metals, calcium-like deposits, and salt-like crystals. This phenomenon is accompanied by chronic pustule formation due to the deposition of micro-crystals, readily visualized under dermoscopy, which are present in all lesions. It is important to note that the patient has a history of Ehlers-Danlos Syndrome and Perforating Collagenosis.
If you, or a colleague within your network, possess a keen interest in investigating such a rare case and contributing to the field by naming this new condition for the dermatological archives, a collaborative effort could prove highly beneficial for both the patient and the researcher.