What’s the Best Approach to Treating Stage IV Melanoma?

Lilit Karapetyan, MD, MS, FACP
Moffitt Cancer Center
With stage IV metastatic melanoma, the cancer has spread to distant body regions, mostly the liver, lungs, bones, gastrointestinal tract, and brain.
Your doctor will examine two factors to determine how advanced stage IV melanoma has become. One is the location of the distant tumors. The second factor is an elevated serum lactate dehydrogenase (LDH) level, an enzyme responsible for turning sugar into energy. The higher the LDH level in body fluids, the more damage the cancer has done.
Treatments for Stage IV Metastatic Melanoma
The primary tumor and any enlarged lymph nodes to which the cancer has spread may be surgically removed or treated with radiation to treat stage IV melanoma.
Cancer that has metastasized to internal organs may also be surgically removed, depending on whether the tumors are causing symptoms, where the tumors are located, and how many tumors have formed. Treatment options for metastases that cannot be removed include radiation therapy, chemotherapy, immunotherapy, or targeted therapies.

[@bdyall8948]

My dermatologist sent in 2 suspicious skin samples for biopsies. One came back as a Melanoma. My first. I see my dermatologist 2 or r3 times a year. I will have my surgery in 10 days. A diagnosis of Melanoma is big wake up call. Reaserch has made great strides in combating this very serious form of cancer. I feel quite optimistic !

[@pattim173]

When it enters your brain, your lungs and your intestines, let us know how you make out.

[@davidfreer5041]

Thank you Aim for all you do. Would it be possible for you to mic up your speakers and not have a general microphone that picks up all the noise in the room (coughing, doors slaming, ambient noise, etc). As a stage 4 Melanoma patient, I really wanted to watch this, but I can not hear the speaker well enough.

[@Victor-Steven-Aguilar]

Great Job AIM, so thankful for your work. Any chances of getting references for cited research?