Acute Pancreatitis: Etiology , signs and Symptoms, pathophysiology , Diagnosis, Treatment
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- čas přidán 12. 06. 2024
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Acute Pancreatitis: Etiology , signs and Symptoms, pathophysiology , Diagnosis, Treatment
Overview:
Acute pancreatitis is an inflammatory condition of the pancreas commonly caused by gallstones and alcohol use. It presents with sudden, severe epigastric pain, nausea, vomiting, and epigastric tenderness. Diagnosis is confirmed by elevated serum lipase or amylase levels and characteristic imaging findings on contrast-enhanced CT abdomen. Severity and prognosis can be assessed using clinical scoring systems such as Ranson criteria and APACHE II.
Clinical Manifestations:
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Epigastric pain: Sudden, severe pain in the upper abdomen that may radiate to the back.
Nausea and vomiting: Common symptoms accompanying the abdominal pain.
Epigastric tenderness: Tenderness on palpation of the abdomen, typically in the epigastric region.
Diagnosis:
Laboratory tests:
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Elevated serum lipase or amylase levels ≥ 3× the upper limit of normal (ULN).
Other laboratory abnormalities may include elevated liver function tests and inflammatory markers.
Imaging:
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Contrast-enhanced CT abdomen: Characteristic findings of acute pancreatitis include pancreatic enlargement, peripancreatic fat stranding, and fluid collections.
Management:
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Supportive care:
Fluid resuscitation: Intravenous fluids to maintain adequate hydration and restore intravascular volume.
Analgesia: Pain management with appropriate medications, such as opioids.
Antiemetics: Medications to relieve nausea and vomiting.
Early enteral nutrition: Initiation of oral or enteral feeding as tolerated to support nutritional needs.
Identification and management of underlying cause:
Biliary pancreatitis: Cholecystectomy to remove gallstones or treat underlying biliary pathology.
Hypertriglyceridemia-induced pancreatitis: Long-term lipid-lowering therapy to prevent recurrence.
Complications:
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Localized complications:
Necrosis (necrotizing pancreatitis): Areas of pancreatic tissue death, which can become infected.
Pancreatic pseudocysts: Fluid-filled collections that develop in or around the pancreas.
Walled-off necrosis: Encapsulated areas of necrotic pancreatic tissue.
Systemic complications:
Sepsis: Infection spreading from the pancreas to other parts of the body.
Acute respiratory distress syndrome (ARDS): Severe lung injury causing respiratory failure.
Organ failure: Dysfunction or failure of multiple organ systems.
Shock: Life-threatening condition characterized by insufficient blood flow to organs.
Complications of acute pancreatitis are associated with significant morbidity and mortality. Prompt diagnosis, appropriate management, and close monitoring are essential to minimize complications and improve outcomes.
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Brilliant presentation, Doctor. Thank you for your wonderful work.🙏👏
Wonderful video, very informative. Keep up the good work, Doc!
Thank you kindly!
Best explanation.. Thanks sir
Thank you so much🎉 god bless the team 🙏
When I went in to the hospital, I was told I had textbook apendicitis, and a med student was even brought over to poke my abdomen to see how perfect of a case it was - then, when the doctor found out the imaging came back fine for my appendix but my pancreas was inflamed, he said it was likely caused by excessive alcohol intake and that they wouldn't give me any pain medication because it was possible I was just looking for a fix. Horrible experience and a traumatic time.
Very nice info, thx
thank you for the explanation
Thank you sir for this wonderful video.. Sir plz make a video on fracture of femur
Ultimate video for medicos .please keep on making them.
Tysm
Thank you for sharing 😊🙏
Awesome Lecture sir!!
Thanks so lot!!
Tusm
Great 😊
very good amazing
Mind-blowing explanation...!
Tysm
Excellent👏 video, very very informative so easily comprehensive video ever found, keep going❤❤❤
Tysm
fantastic video....thanks for sharing
Thanks for watching!
Very informative video.
Sir please make a video on chronic pancreatitis also.
Yes for sure 🤝🤝🤝
Ultimate explanation ❤️
Glad you liked it
Thank you so much Sir for this awesome session & clearing my concepts🙂🙏🏻
It's my pleasure
Veryyyyyy nicely explained
Thank you so much 🙂
Nice
Dont ignore ............ I know this pain. .... Me also pencreatitis patient.. Right now... 😢😢😢😢 lifetime no alcohol
What was the cause ?
Take care bro .... No red meat no alcohl pain abdomn stomch
Super class
Super
Tq
Sir I have a one question
My relatives suffering acute pancreatitis .it resolved by medicine . please tell me it is serious case ??
What the treatment sir?
First time I felt this pain was at work. I felt stab in my stomach I went to the bathroom I thought maybe I had gas, cause that’s what it felt like. It hurt to push. After that I had upper stomach pain one day for work but it went away. Now, I have it and it’s been 3 days and I’ve taken pills or even alkasetz and it has not gotten better. I am not sure it it’s this? I also feel like I need to 💩 when I feel this I’m afraid
Thank you for this. Very informative. Sir can you please do a video about gallstone pancreatitis pathophysiology?
Trust me its not fun having this
Sir can we do gym in acute pancreatitis. Plz reply
Is the pain steady, or sudden? I have pain attacks that last 15-30 minutes. I take beta-blockers.
Mine last 2 days and goes away just few hours
Mine last till I get medical help
Dear Yeh meri ultra sound report hai iska kya matlab hai (Suggest s amylase rule out ? Early acute pancreatitis H/o alcohol binge present ) aur iska kya solution hai
I too had Same report
8688794150
Very useful
Thank you
Thanks 🥺❤️.
Thanks Sir
🤝🤝🤝🤝
i am having pancreatict problem can u suggest me some medical treatment plz
Is acute pancreatitis curable except damage organ's
My uncle's pancreas is fully infected and swollen, can he survive from this please reply anyone please it's an emergency. 🙏🏻🙏🏻🙏🏻👍
i had acute pancreatitis. my pain started before Christmas and i was finally diagnosed correctly Jan 4th. My husband said i was just constipated, or that i had gas pain. dr said ulcer. ER said i was fine and sent me home. When I was finally diagnosed i was in 12/10 pain screaming. no one would listen. fentanyl was ineffective. I required 3 days hospitalized. they gave me fluids i could not eat, and i needed dilaudid every hour
Me too! Our story is exactly the same! My husband thought gas too. I needed dilaludid every hour. Im actually at the hospital now for it. Glad you’re doing well 😊
How was it able to be diagnosed? Blood test? Or scan
How it was diagnosed??
Is itchy skin a symptom of pancreatitis?
I see hepatorenal syndrome with it. These patients are most challenging.
My brother is in hospital with this now, he had the pain on and off for more than 6 months but was not seen by a doctor due to covid and that the pain went away, finally a doctor saw him and sent him to hospital with suspected infected gale bladder, they did scans and said 75% of his pancreas had died and they think it was to do with gale stones moving onto the pancreas, he is only 32 and has been there for 4 days so far but we still dont know if they will remove the dead flesh or not.
Plx make in urdu
Pancreatatis why fever high
My uncle died because of this on august 29 2020
My brother died coz of this last year...within just 4days of hospitalization
Morphine is not used as it causes spasms of sphincter of oddi... Pethidine preferred
ARDS is acute not adult right?
Its adult actually
Acute
❤️❤️❤️
Thank u
pancreas are really important organ as this is able to maintain the glucose balance in the body....i use planet ayurveda's medication to keep my pancreas healthy I am also suffering from the pancreatitis
Bro i am also acute pancreatitis petient ... 2023 August hospitalized .... Aftr hospitalized can't eat red meat no alcohal all cut. How can keep up my pancreas healthy tell me.
This is why @AVICII died 😔
%
Eating muscleblaze is safe Acute pancreatitis patients🤲🤲🤲
💉💉💉💉