How to die young at a very old age | Nir Barzilai | TEDxGramercy
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- čas přidán 29. 09. 2014
- This talk was given at a local TEDx event, produced independently of the TED Conferences. Aging is a common risk factor for many diseases, including cancer, diabetes, Alzheimer’s, and heart disease. Rather than treating each disease separately, the most practical approach is to delay aging altogether. Learn about our efforts to help everyone die young at a very old age.
Nir is a Professor of Medicine and Genetics at the Albert Einstein College of Medicine and Deputy Scientific Director at the American Federation for Aging Research. He has pioneered breakthrough research on the biology of aging.
About TEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
Attitude, spirit, nutrition, proper sleep, and yes, genetics. Mother died last month, and she was a wise, wonderful.... 95. Heart, lungs, kidneys fine till the end. No illnesses at all, she just wore out, went to sleep one evening, and peacefully joined her ancestors.
Cynthia Hawkins i
My father would have done the same as his own mother did. But the medical system killed him. The "best " of care in the greatest NY hospitals. I will never get caught up in big pharma web.
Trump
@@LilyGazou The same medical system which, through in its totality with public health measures, (e.g. vaccination, germ theory etcetera) and direct intervention, probably played a big part (along with better living conditions) in his lifespan being what it was rather than the lifespan of an untouched human of about 30 years? And I don’t understand what part ‘Big Pharma’ would play in a hospital or your future health. And how did the ‘medical system’ kill your father? Or was it the condition(s) he had?
@@junlopez6819 ? Did you want to say more about Trump?
Thank you Nir Barzilai for clarifying what I was wondering about for so long. Stay well and live long.
This was recorded 8 years ago, I just watched it now too.
Cancer might be reason why the majority of otherwise healthy people can’t die old. My heart goes out to them. It runs in my family. I just hope to reach 70.
It can sometimes be reversible with nutrition. Autaphagy will eradicate damaged cells (aka cancer) induced by fasting. A known fact is carbs and sugar also FEED the cancer to keep it alive. Also, doctors do not have many nutrition classes in Med school and why it's not really considered as a medical prevention for cancer. It is so difficult for us in Western society -myself incl- to change our eating habits and contemplate the discipline of routine fasting.
Better to concentrate on living the life you have each day a than fixating on being around for 100 years. Some people have luck with that most don't for 1001 reasons
Excellent. Thank you very much
The book "Life Extension" by Sandy Shaw and Durk Pearson 1980 is the book that introduced this concept to the contemporary world.
He's last words are very important: If we want science to figure out even more crucial details about how to slowdown our aging process, then we should demand more research on the aging process. So the question is: Why aren't we demanding more research to be done? Why are so many people just simply accepting their own natural aging, yet they're very scared to die.
Even if only 2% of the people who reach age 100 are vegetarians, that not necessarily mean that those young people who today are becoming vegans will only 2% of them live to be age 100. Those people who are today reaching age 100, when they were young there have been very few vegetarians back then 80 - 100 years ago. So back then, not many people had a chance to eat the right type of food (vegetarian) and so be able to live very healthy lives.
So no wonder why only 2% of them are vegetarians who are currently able to reach age 100 and over.
Make no mistake, those young people who are today choosing to eat a fully plant-based diet for the rest of their lives, there's a good chance that a large percentage of them will live over 100 years old and older, may be as far as 130 -150 years of age. But of course, we can only confirm and validate this prediction when that time arrives, and we have the data to prove it. Until then all you can do is to eat as healthily as possible. And that means: fully plant-based food and positive thinking and constant learning.
The questions need to be asked to the pharmaceutical companies. They are criminals
This talk had no useful applicable information. At the end he mentions that there are drugs being used to cure diseases but are very good for delaying aging, but he named not one. This was for me a waste of time.
Metformin for diabetes. Statins are a class of drugs often prescribed by doctors to help lower cholesterol levels in the blood. By lowering the levels, they help prevent heart attacks and stroke. Studies show that, in certain people, statins reduce the risk of heart attack, stroke
@@crand20033 can statin delay aging??
@@SI-ln6tc They can delay death.
Metformin may be good. Statins make life worse.
Check David Sincair on Joe Rogan Podcast
Leaky Gut Syndrome has major health issues connected to it. Chronic Acid Reflux affects 80 million Americans. Keeping a healthy gut environment is vital to good health.
First of all, I definitely agree with him regarding the fact that good genes is the key to longevity. You can practice all types of various healthy lifestyles but won't get longevity if you're prone to getting certain diseases.
Having said that, I felt this talk was more a commercial for the drugs that his company is selling but can't sell enough of due to FDA not recognizing aging as an illness.
Personally, I don't think any drugs will achieve the results that many of these people have unless you start manipulating DNA before you were born. The people that are alive today, at the most to extend their life, is to maintain a healthy lifestyle.
One day, we will get to the point where DNA manipulation will be a common thing. Now, whether that is a good thing or bad is up for debate.
Dr. Mark Hyman stated, based on his research, that we can actually "turn off" disease genes using certain lifestyle habits. Gene certainly have a role, but do not determine our fate in and of themselves.
Epigenetics?
Longevity with good health is exciting but the cost of living longer may be as problematic as living longer sick
Very true but sad.
Good to see Irving still actively investing. I'm inspired.
I'm pretty certain that by the end of this century reaching an age of 100 will be very much the norm.
in only 20 to 30 years we'll have close to 10 Billion people on this planet! And they all want to live to a hundred years old....and of course with all the luxuries we in the west enjoy now!
Do you really think the planet can cope with that?
In Nature, you know, there is this phenomena of self-regulation. In 20 - 30 years, being 80 will be the new 60, thanks to improved lifestyle, food, medicine.. However, I also think that Humanity will level-up it's population at some point in the next couple of centuries, due to various factors. After 1000 years, the way we humans reproduce will have taken significant transformations due to advances in technology that never were before. So, human history will take leaps and bounds way more than we have seen thus far. ;-)
@@mindvolution it wont be human.
You have a wild imsgination, are you
12 years old?
@@mikesi5531 You are mistaken soo many people dying right now & HUGE drop off in births especially in Europe.
Do some research & spare us your
wild imagination. It is infantile.
@@epiphanyx3705 Do you realize my comment is 4 years old? The world has changed since the greatest experiment of all times and I'm aware that many are dying because they believed their governments and so called experts.
I'm going to look for that other video on longevity drugs.
Maybe get them for my parents, uncles and aunts.
EXCELLENT. So true.
Hi Louise..... How are you doing
Eat less drink water more and live more....keep fasting once in a month or week...
You can't stop a ticking clock, but you can slow down time. This is exactly what I have done by paying attention to my circadian clock and environment. I will be 60 in a few years. Our heteroplasmy rises every decade. Mitochondria is the key.
I find when I drink enough, things tend to slow down, too. Or maybe that's just me.
Starlight - If you can slow down time, or a clock, then why can't you stop it? Mitochondria is ONE of the keys to the aging process. Telomeres are another, along with more factors.
Hello.....How are you doing
@@timjorgensen4836 q
Story of Irving Kahn and his family starts at 7:10
Very interesting
“at least one graph in a lecture” 😆
👏🏽 👏🏽 for this entire video
Eat healthily, work spiritually satisfactorily, and exercise daily. We need this habit from the very early childhood. Parents are toxic.
Why?
what is eat healthily? It is Not vegetable munching thats for sure ?
Start listen from 12:50
This intro 💚💚💚💚💚
completely useless talk, what was that. The title was misleading and i continued listening expecting something good to come at the end.
Thanks for saving my time ...bs meter was going off big time within the first three minutes... 5:54... I'm out
Of course only 2 percent are vegetarians and most were smokers during their life time. But thats just because it was way more common not be vegetarian and to be a smoker in the old days. May be more people would have been able as long as Irving Kahn did, without smoking. We lack the data.
I fast since I was 13 years old in the month of Ramadan
@Saša Šijak 😂😂😂
People living healthy life is bad for the economy, our leaders know that. Forget about any ideas of changing it.
Dream on...... dream on......
Well, if we don't havelur genes analysed, we may never know - until it is too late :-)
However, I miss the mention of epi-genetics, and more important - as said below - staying active (working, which our society doesn't let us) as well as having a busy social network!
Yes, I like this speaker ... has some good points ..
70 Going On 100
kynan bridges
Carroll Hoagland - Change that from "70 going on 100" to "70 and will just keep going".....DON'T put a limiting cap on your age!
Do some research about the benefits of fasting. Fasting is hard to monetize and therefore gets less recognition than it deserves. Dr. Jamnadas is a cardiologist who provides some excellent content on CZcams. His talks for the Galen Foundation are excellent.
The things he has seen..wow
Australian aborigines can reach the age of 110 - 120. Some Japanese Islanders also can reach age 110 - 120. The fossil record of pre-civilized hunter gathers shows a life span of 80 - 90 years. A life span of 120 years is your birthright if you live healthy, have honest relationships and a fair degree of luck.
we are all of what we ingest during our lifetimes. chronic disease is a fairly new thing. diseases often come from pollution. pollution is a problem.
darren dwyer your environment and your reaction to it.
imagine the genome is like a ticker-tape that goes into the ribosome sequentially to produce the correct proteins at the correct time intervals. if the ticker-tape (genome) is shorter, maybe people live shorter lives. If the genome is longer, maybe people live longer lives. Maybe you could make life extension a reality by extending the length of the genome?
I aged 20 minutes listening to this talk.
With all the stress on the ecology and environment by each and every individual i don't see the purpose of living long. What's the point of extending life beyond the productive years, one is just a burden on the society.
It's so much better to be rather recycled and have another fresh go at life
the point is that we all want to live healthy & die healthy.
The four brothers he was talking about were deff born before 1910 if you do the math (some of them anyways)
worse thing is that cholesterol isn't the cause of heart disease. Inflamation is the cause of heart disease, and that's mostly caused by sugars.
elaborate abt sugar plz...tx
Exactly!!! That cholesterol example was pretty misleading. But it did show how "scientific" he is. Lol.
yash karani watch "carb loaded". It's on CZcams. then do your own research.
Oxidative stress.
@@gaurd3 He doesn't even know how to use google.
A typical misleading title to this post. There's no "how to" in this presentation..
Sir I think I might take exception to your theory. Are you saying that aging caused these diseases? I think it was more a matter of time taking its effect on people who are not attending to the lifestyle related diseases that you mention. So I would say that it’s a matter of time not of aging.
That was a complete was of time. He didn't say any thing about how to die young at old age.
Fasting combined with avoiding all processed junk foods and eating zero refined sugars benefits all our health.
I just was thinking the same
He didnt give any tip , any useful info
@@russellbrooks23able True just make sure to avoid focusing on stressful situations. Instead focus on the beauty of life’s different aspects.
OMG WHYYYYYYYY the looooong ads now!!!!
didnt mention telomeres at all !?
They may be more at effect than at cause imho.
I was with him all the way until he mentioned drugs - and then I think "follow the money"
Steve Pickering
Metformin? Cheaper than water.
"One gram of fiber for every one hundred calories. Only drink water." - Mr. Atwater
What if I like to drink attractive woman's saliva? Is that allowed by Mr. Atwater ?
There are a lot of interesting things that relate to our general health and longevity. The thing is the average age has stopped increasing in some countries. Mainly the usa but also russia and france. We are also seeing that the newer generations are less healthy. They can run less so they have worse physical health, less strength and they are also heavier.
Most kids growing up don't grow up in environment where they need to perform physical tasks. They exercise less and there is cheap junk food everywhere. They are driven to places, they don't walk and they don't exercise. There is more financial stress and our kids who are now entering the workforce will be the first generation who will earn less than their parents. All the while costs have gone up. And when they work more of the work is done sitting, not moving. Sitting still is a silent killer.
Wealth, exercise, mental health, physical ability and strength, obesity, lifestyles. These are all things that correlate with living longer and healthier. Genes of course help, especially when we look at the extremely old people. But our kids have all of this worse. Doing 3 hours of mild of exercise per week is the same as losing 30lbs or 15kg for example. The newer generations, exercise less and are heavier and massively obese even at very young ages.
So as far as aging go we may have actually already peaked. Newer generations probably won't live as long. Only thing that makes our kids live longer is the medicine. A lot of illnesses and cancers are no longer a death sentence. We catch those issues earlier and treat them better. But at the same time we are burning the candle from the other end faster. When those kids get older they are most likely going to be less healthy and die younger. Unless we discover new medicine that can treat obesity, heart and cardiovascular related health issues. Because those are going to get worse, a lot worse.
So no real answers
why you are not talking about Chronic Disease gone upto 90%
I "listened to the top comments" ... didn't listen to the talk ... Only 669 Thumbs Ups out of 105 thousand 'listens' ???
I don't think intermittent fasting will help with growth hormone much. From what I heard it needs to be 24 hours or more of fasting.
The human growth hormone (hgh) is made by the pituity gland. it starts producing hgh once the stomach is at rest & no longer digesting food. the peak production time is between 23:00 & 02:00. that's why they used to say "eat breakfast like a king & dinner like a pauper." that's why the gurus say, go to be hungry. peace & love to you.
Sorry, You are wrong. I suggest that you listen to dr. Sten Ekberg, about intermittent fasting
You "heard" wrongly. Intermittent Fasting is also not eating for 18 hours, e.g. nothing from 5 p.m. til 11 a.m. , and it works as a weight reduction tool.
I thought for sure he was going to mention fasting and autophagy.
What's autophagy?
I’d like to see research on the effect of a healthy diet during childhood on health-span. I bet it is considerable.
no practical information passed to audience.
yep, typical ted host. self-aggrandizing promotion.
At whatever age you expire I hope it's as you like it.
Personally, I choose instantly and without warning - a car crash or lightning strike will do. I will come back to haunt anyone who puts me on "life support."
He lost me with the fake fact that Cholesterol is a x3 marker for heart disease. I am sure he meant to say elevated Homocysteine. Genes may load the gun but it is lifestyle that pulls the trigger. My hero is 104 and runs marathons. My hero is fit and not a blob.
Robert Redfern that must have been what he meant: more beetroot please!
Aging is a number, you can make it bigger or smaller. We think that age is disease and solve it another will appear, long life with longer healthy period, work at old age, eat some natural probiotice ie fiber
There he goes again at the end with the notion that if insurance doesn't pay for a drug, you can't have it, as if these insurance companies are the ultimate gatekeepers to whom we must grovel to get what we want.
Oh, how helpless we've been trained to be!
I agree that we are WAY too beholden to the insurance companies. In fairness to the speaker, he used the word demand as opposed to grovel, and indeed, I believe that we need to demand better health care. However, we can't afford to simply depend on drug companies and insurance companies - time after time, they've put their profits far ahead of our health. Also, as great as the drugs he mentions may be, they are certainly NOT the ONLY factor. Mr. Irving stated that having a purpose was most important in his case. Sleep and diet are definitely important also. And smoking, for example, might not kill everyone, but statistics have proven that you'll tend to be a whole lot better off not engaging in it.
I agree we have been program or trained to believe that we're helpless and powerless. And of course there is always voice, some one that comes out, crawls out of the bushes willing to sell us our power back. However this manifests in our lives the ability to turn within for (me) seems to be lifelong based on situations by situations.
Peace be with all reading this.. or better said may your personal power be restored.
Are you an agent???
@@msmith53 no but you are.
not one...singel....PERSON! ill die alone
OK, another Ted talk that don't respond the title question. Wasted time.
Is that even real introduction!?
making example of that dodgery old man who owns investment company as still working is unfair. he owns it and can do what he wants.but if he was employee he was made to retire 40 years ago
perhaps smoking the cigarettes reduced their appetite considerably thus resulting in caloric restriction and subsequent slowing of aging.
You missed his point - those people had genetic advantage. That is all. They are outliers for that reason only. Clearly implied by what he said.
Maybe they smoked pure tobacco and not the nicotine-treated cigarettes. Maybe.
Did he just say that we need to take drugs to be healthier? I cannot believe this! World is going crazy. I like TED but this talk is a waste of time.
Absolutely breathtaking! This content is amazing. I discovered similar material, and it was mind-blowing. "Adapting with Aging" by James Crescent
a very long introduction, without a specific answer how to do it. I believe it was wasted time😔
Enjoy every day and when the grim reaper comes so be it.
I didn't find anything significant.....drug is not a choice....unless u have to choose between life and death
said nothing in reality
Age is a lie. Would you EVER say electricity ages?
whats your point? plz elaborate....tx
My recipe is: Never take a pharma pill and, instead, provide the body with all the minerals it needs.
I have tried everything to stop my 3 - 5x weekly migraines without pills. I eat "pure" and organic, sleep 7.5 hours, exercise a lot, and my iHeart device shows an "internal age" of 42 when I am 66. In order to live my life, I have to take zolmitriptan. I drink organic mineral tea. Makes me so frustrated! My mom had them and my daughter gets them really badly.
that will only allow you to live a normal lifespan not extend beyond our current biological limitations.
@@lighthealerastrid1465 Hi Antonia. If you have tried everything else and nothing has worked, then I'd like to suggest one more. Drink lot of water and make it a habit of going to the bathroom as soon as you have the urge to urinate. Don't hold it for long. I don't really know what the connection is, but it minimises the severity of the migraine attacks and steadily decreases the frequency too.
Sindhu CVM Thank you 😀
@@lighthealerastrid1465 Practical Ayurveda believes retaining urine tends to trigger migraine attacks. I was able to feel your anguish. That's why replied. I hope it works for you and helps you get out of your dependency on all those tablets. A lot of grape juice (not the fermented kind, 😁😁😁) helps too.
I was disappointed when he brought up cholesterol and lost all respect when he brought up pharmaceuticals at the end.
Too bad you were disappointed. Maybe you did not get the point of what he is saying. Why not ask why some people who do things "wrong" live so long? Or why some pharmaceuticals appear to lengthen life? The body is already a mass of chemicals, but how a particular body handles those chemicals varies, and it seems to depend on genetics. His point is that it will help us to figure out why that's so.
Agreed. Some of the information was interesting, but using cholesterol was a poor example. And then pushing synthetic chemicals was ridiculous.
He's relying on the information given by the pharmaceutical companies. They form studies in order to support their products. Back around 2010, there was a study done by the manufacturer of Lipitor, which showed that people who take lipitor have a 0.1 less percent chance of having a heart attack. Yep, zero point friggin' one. So they just keep on doing more and more studies.
you do not know how to cure cancer
you know how to cure ageing
Except, it has been proved that cholesterol has no correlation with cardio vascular diseases, and vegetarianism isn't really the best diet of all - quite the contrary (it's more about how much and when you eat, and how nutritious that is). Add to that that one of your subjects smoked for 80 years... you'd probably want to revisit some of your assumptions ;)
please can you tell me where has it been proved that cholesterol levels ,such as HDL,LDL and others, have no correlation with cardiovasculaar diseases?
That would be the Framingham study. Besides, correlation does not equal causation, but I suppose you never learned that. Now you know. In fact, once you're over 60, having elevated cholesterol actually decreases the chance of dying from a heart attack. Put that in your pipe and smoke it.
@@kapmahm : I have a friend who is 71 years old with total Cholesterol of 352. He's still working and active, drinks almost everyday except Sunday. What gives?
@@d.e.b.b5788 You don't know what you are talking about. See my earlier replies to some of your assertions.
Don't know why people think that reading only NON-fiction is something positive. Only way to access your imagination is through reading fiction. Judging his background (finance), he likely has no imagination.
I understand where you're coming from, Liz but your premise is erroneous. I never read fiction too and I have a huge imagination. It is the other way round: We don't read fiction because we have enough creativity and fantasy in our heads to extrapolate the non-fiction we read and create something new and unexpected from it. We get inspired and enlightened by truth and facts rather than by the hitchhiker's guide to the galaxy and we expand the realm of possibilities based on reality and common sense and not on mumbo jumbo and scientific rubbish. However, that does not mean that we've never watched Star Wars, Sponge Bob or I Dream of Jeannie, we just don't read mystery and fiction because reading is so time-consuming, the limited payoff causes an intellectual imbalance. Also fiction confuses you more than it makes you creative. With that being said though, we could easily write novels ourselves, it's just not our cup of tea. By the way I am not from a financial but from an artistic background.
@@PianoGesang Very well said! You either have good imagination or not. Fiction doesn't really help you enhance it in most cases but it could actually help your imagination go further influencing new ideas, again in some cases. I only read science and it brings me more ideas than fiction could ever do.
Waste of time. The answer is genes and pharmaceuticals? Tells us nothing useful and I for one don’t buy it.
What is he trying to sell
Nmn
Seems it’s all about genes (oh, and a loose end about growth hormone!).
He lost me with the comment about cholesterol. That was disproven by the Framingham study back in 1999, and then, because it didn't agree with the conventional beliefs, the medical community buried the results, and just continued to do more and more studies trying to prove their cholesterol hypothesis. They all forgot one thing: When the cause of a disease process is shown to be positive for that disease, it's always positive in a large percentage and it's positive all the time. You don't see more than half the population being exposed and not getting sick from it. I get told that if my cholesterol count is elevated, my chance of dying from a heart attack is 14% greater. Well, if they are so sure, why isn't it 100%? Or even 50%? Simple. Because there's something else causing it. Those 14% had other health problems besides cholesterol which was killing them too.
how authentic is that chol..... study?
Did you even bother to look it up? Or do you just want me to tell you again? If you are in school, perhaps you'd like to do a term paper on the politics of the lipid hypothesis and it's effects on medical research, funding never ending studies attempting to prove that cholesterol is the cause of heart disease and the pharmaceutical corporations that have gotten very very rich over the past 40 years selling pills to lower cholesterol, even though they were never able to prove that elevated serum cholesterol is the cause of heart disease. Now, why would they need to keep doing more and more studies if what they are desperately trying to prove, were true? Answer: Because it's not. When studying causes of diseases, if you find the cause, it's true all the time, and shows up positive in a very big way. What they are finding instead, is incremental slight increases in heart disease in SOME people who have elevated cholesterol. But they ignore the populations of people with high cholesterol that have no heart disease or strokes. Why would they do that? Simple. MONEY. There is much literature out there about the cholesterol myth, so much so, that the FDA changed their dietary guidelines in 2014 again, this time once again including more fats in the diet.
All this because a guy named Ancel Keys, a doctor back in the 40's, who carefully constructed a bastardized study that made it look like cholesterol was the killer. How? He looked specifically for populations of people that had high cholesterol AND high heart disease. His famous '7 countries' study was derived from a collection of 21 countries, he only used the ones that supported his hypothesis, discarding the rest. and he went on to make millions perpetuating his myth.
Hi, very nice to read your comment. Can you plz tell me where do you find all these histories and stories to read from, which website or books? tx :)
@Jack Grimes Oh please - the conspiracy that all governments are trying to kill us has lost traction. There are good reasons the UK Government uses a tax on sugary drinks - please take time to actually read something authoritative.
@@yashkarani3601 Go to google. Type in 'Framingham study'. Try links. Same as everyone else does. There you go. Now you know how to use google.
😂😂👍🏻✔️🔙
.. if Ben Shapiro were giving this talk he would repeat the point a few times and be done in 20 seconds ..
I don't doubt that he can say a lot in 20 seconds, but he doesn't exactly Inspire hope for the future...
11:57 "something very interesting about those people": They are all jewish.
Ahhhh..less food allergies are reported in Israel than anywhere else worldwide!!
INTERMITTENT FASTING!!!
talk to baby's build brain s
Interesting talk but I wish he would stop walking over and back like a caged lion
The guy is blaming cholesterol....he is out of date....
harry viking
It is you who is out of date. Try reading authoritative sources, not wellness blogs.
Hard pass on any investment firm that has the word CON in it!!!