Immunology Lecture 16 - Type IV Hypersensitivity Reactions
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- čas přidán 22. 08. 2024
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This lecture covers T cell-mediated delayed hypersensitivity reaction (Type IV). Sensitized T cells release cytokines that activate macrophages and act as chemotactic agents for inflammatory cells. Issues like Type I Diabetes Mellitus, Multiple Sclerosis, Guillain Barre Syndrome, Hashimoto's thyroiditis, Graft vs host, contact dermatitis and PPD are talked about. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
This is the best video regarding type 4 hypersensitivity! Thank you!
Fantastic!!!! Thank u n God Bless u n ur loved ones. 👏👏👏
Bokan sb: you are correct MS affects white matter of the CNS. These are Oligodendrocytes.
most clear concept.. make very nice......thanks sir
You sir, are an excellent educator.
vwziful - could not reply to your post. Something with this new commenting system prevents me from replying to your post. Hope you can read this comment: I am talking about the blistering due to contact with chemical substances or plants.
Immunology Video: Hypersensitivity Type IV
czcams.com/video/TJM-lBc9rWU/video.html
Marvellous job sir ! Respect
Thank you. Find more lectures on drbeen.com.
Dr. Syed, thank you for the helpful video! Just an aside, your handwriting is beautiful.
thank you dr and i hope my presentation on type four will go better you really sacrifice.you are hero
seriously u teach in the best way..😊 thanks alote for the video
Good to know. There are more lectures to keep you happy. Visit: www.drbeen.com/catalog
Glad that you like our teaching. Please find more videos on www.drbeen.com/catalog
Best
Mobeen
Thank you Dr. Mobeen
You are welcome!
guillean barre is a type 2 hypersensitivity due to antigenic similiaruty to camplobacter.
Very very informative and knowledgeable
Thank you!
Very nice teaching sir thanku very much keep it up god work for students
Sir, please make a complete details video on 'polyclonal and monoclonal antibody "for exam. All this video on ' hypersensitivity reaction' helps me a lot. Thanks to you for this.
Thanku much Sir for hypersensitivity lectures.. these helped alot .. thanku once again
My pleasure. Check out drbeen.com for more lectures.
Mind blowing..It is Very helpfull lecture
very very well structured! i really enjoyed it!
have you ever considered doing more pathophys / pharma? ;)
thank you so much . you are really great doctor
Thank you!
Very interesting teaching thank you so much, have u made any video on Serology tests?
Not yet.
MS = demyelination of oligodendrocytes
GBS = demyelination of schwann cells
very clear. thank u so much.
aditya malladi you are welcome!
Thank you Sir...it was super
Thank you. Helpful and quite in deapth.
hi, was just wondering if B cells would be involved in any aspect of this immune reaction? I understand that antibodies are not produced but do the B cells act in any other ways?
You are just amazing thank you so much god bless you
Thank you very much u are indeed great
You are most welcome. Study well and continue being the best! Check drbeen.com for more lectures.
Thank you very much doctor mobeen ., please is there a video about hypersensitivite type 1 and 2 !!!?
+imane amy yes. Check in the videos or visit drbeen.com and go to immunology module (it is free). There you will find all videos in a list.
Thank you and God Bless
Thanks drbeen, very good explanation
Pleasure. Check drbeen.com for more lectures.
Thank you sir🥰🥰😊
Amazing Dr Mobeen
I really gone fan of u sir
Thank you, dear. Study well.
thankyou so much. god bless you!!
sir, type 1 diabetes is disease which is due to type 4 hypersensitivity section- intracellular pathogenic antigen where macrophage activates T1cell which in turn activates macrophage by IL12 and IFN gamma cycle and cause damage to tissue. ok but what is the pathogen here?
No pathogen is involved for type 1 DM.
Superb sir nice explaination
Awesome! Thank you.
You are welcome!
Sir,
Please upload a lecture on coagulation cascade and coagulation tests integrated within.
Thank you Sir.
Expecting a positive response.
superb
Thanks
thanks a lot ... it was helpfull
Is der any specific pathogen for multiple sclerosis? like for tuberculosis myobacterium wich goes into the body n causes this reaction
hello dr saab..i have a query in delayed hyper sensitivity reaction when cd4 is activated by antigen presenting cells (like in case of tuberculin test) they became sensitive and wait for the antigen to re enter the body. why they don't follow the tradianal path like garbbing the tuberculin molecule presenting the antigen to b cells and provoke a humoral response instead of cell mediated and damaging the tissue by casies necros?
and thank you for your contributions
+Sulaiman Gran it is not that the cells will only work through one pathway. It is the predominance of the result. All mechanisms that can engage in a given situation do become engaged. Some are more effective than others.
Thank you, the lecture was laid out in a very organized manner and was very inclusive. The camera man could take a little less artistic license.
Thank you for your comments Eric Watkins. I enjoyed the camera man's license thought from you :-)
In Type 1 DM and MS,
can i say that the lymphoctes are sensitised in the first exposure to the islet of langerhans or schwanna cells. then they become memory lymphocytes and they just attack these cells again? So does this mean that memory lymphocytes can straight bind to the antigen and does not need any help from APC?
thank u so much sir...can u plz upload hypersensitivity 2 lecture as well :)
+aakash sharma will do!
Will you plz upload type 2 hyper sensitivity?
Tq
warthins tumour is also a type 4 reaction
Sir,which one is for T Cell-mediated Cellular Immunity?
Sir ,,,make a video about type2 hypersensitivity pls
but blistering in pemphigoid vulgaris and bullous phemphigus is type 2??
same with candida test ri8
Where do you find the informations? in which book can i find it ??
which type of auto immune disease does crohn's disease come under?
Dr what about costimulus for Cytotoxic T cell activation in Contact Dermatitis?
Can killer T cell function properly without co-stimulus Il-2 ???
Co stimuli is not needed for killing function, it is only required to activate CD8+ T cell
He is actually talking about memory cytotoxic t cell in skin formed after primary exposure the work in kind of same way as memory B cells they also don't need costimulation for activation
I'm getting distracted by the cameraman moving too much, still a nice lecture
diabete II is hypersensivity ??
No. Diabetes Mellitus type I is.
Please tell the camera man to stop moving around too much!!!! my head is spinning goshhhhhh
Tq