Parkinsonism (Part 02 Final) = Classification and Mechanism of Action of Levodopa and Carbidopa
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- čas přidán 28. 05. 2019
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Parkinson's disease is a progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement.
In the early stages of Parkinson's disease, your face may show little or no expression. Your arms may not swing when you walk. Your speech may become soft or slurred. Parkinson's disease symptoms worsen as your condition progresses over time.
Parkinson's signs and symptoms may include:
(1) Tremor. A tremor, or shaking, usually begins in a limb, often your hand or fingers. You may a rub your thumb and forefinger back-and-forth, known as a pill-rolling tremor.
(2)Slowed movement (bradykinesia). Over time, Parkinson's disease may slow your movement, making simple tasks difficult and time-consuming.
(3) Rigid muscles. Muscle stiffness may occur in any part of your body. The stiff muscles can be painful and limit your range of motion.
(4) Impaired posture and balance. Your posture may become stooped, or you may have balance problems as a result of Parkinson's disease.
(5) Loss of automatic movements. You may have a decreased ability to perform unconscious movements, including blinking, smiling or swinging your arms when you walk.
(6) Speech changes. You may speak softly, quickly, slur or hesitate before talking.
(7) Writing changes. It may become hard to write, and your writing may appear small.
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Sir For Dopamine facilitator its Glutamate antagonist right? You have written Glutamate agonist!
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Sir why MAO A inhibitors are not used in antiparkinson disease??
MAO B is more selective. Selectivity is one of important criteria.
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Sir , Amantadine is actually NMDA antagonist which act as dopamine facilitator.
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Amantadine stimulates CNS,,dopamine shows inhibitory action,sir confusion ho raha hai
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Sir can we give reversible or irreversible antagonist of cholinoceptor so that ach cannot bind to their respective receptor and increase the function of cholinestrase becoz of more accumulation of ach in synapse?
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आपका समझाने का तरीका माइंडब्लोइंग है । मतलब तारीफ करने के लिए शब्द कम पड़ जायेंगे । पुनः एक बार # Thanks a lot 🎉Sir.
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Is there any supplement for the Parkinson's patient...