Treosulfan versus busulfan-based conditioning for HSCT in transfusion-dependent thalassemia

Rita Beier, MD, Hannover Medical School, Hannover, Germany, summarizes the results of a retrospective analysis evaluating the impact of treosulfan versus busulfan-based conditioning regimens in hematopoietic stem cell transplantation (HSCT) for patients with transfusion-dependent thalassemia (TDT). Interestingly, results demonstrated that the CD3+ T-cell count has a significant impact on graft success after HSCT in patients with TDT. This interview took place at the 50th Annual Meeting of the EBMT in Glasgow, Scotland.
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