Intro to Reaction Mechanisms: Crash Course Organic Chemistry #13

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  • čas přidán 30. 07. 2024
  • When we venture to new places, we need navigational tools to guide us. In organic chemistry, those are reaction mechanisms! In this episode of Crash Course Organic Chemistry, we’ll learn all about how to write reaction mechanisms. Having this super useful skill means we don’t have to worry about memorizing every reaction that has ever existed.
    Series Sources:
    Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
    Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
    Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
    Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
    Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
    Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
    McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
    Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
    Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.
    ***
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Komentáře • 105

  • @jamaiya7
    @jamaiya7 Před 3 lety +622

    this is where o-chem all went downhill for me 🥴

  • @drakesmith471
    @drakesmith471 Před 3 lety +321

    To anyone who hasn’t studied Organic Chemistry a bit, forewarning it’ll be bad at first, but it will get better. Mostly I mean reaction mechanisms here but in general. You’ll feel more satisfied and more motivated the more you go on.

  • @MoMn.
    @MoMn. Před 3 lety +216

    Production values are exceptional. Huge respect to your awesome animators

  • @mathfincoding
    @mathfincoding Před 3 lety +145

    I lost track of what's happening 10 episodes ago. This isn't even my major. I don't know why I'm still watching 😂

    • @alic4631
      @alic4631 Před 3 lety +42

      Well this is major and i lost track too 😂

  • @ishikasingh9254
    @ishikasingh9254 Před 3 lety +27

    You guys, seriously, LIVE SAVIOURS. My organic chemistry course is starting next week. Can you imagine my sheer relief at seeing this course on ur channel? Thanks!

  • @marinabarros1721
    @marinabarros1721 Před 3 lety +62

    omg you're such a good teacher. I've already had all my org chem classes and I still don't understand a lot of the basic stuff. My teachers actually didn't bother to teach us this :/

  • @zulanova1209
    @zulanova1209 Před rokem +5

    FINALLY, I GET IT
    thank you ever so much that was a wonderful and clear explanation, and the visuals really helped

  • @ICantSeeYourRepliesDickhead

    Man I'd never miss class, thank you for your help!

  • @cnc321
    @cnc321 Před 3 lety +15

    You are AMAZING! I'm taking Ochem 2 and this is such a helpful refresher for the small details

  • @firefx963
    @firefx963 Před 3 lety +73

    I just can't take my eyes off of the background colors matching in yellow.. 😂

  • @terrabelle9937
    @terrabelle9937 Před rokem +3

    So, so grateful for the people at Crash Course.

  • @iamadarshamrit
    @iamadarshamrit Před 3 lety +11

    This channel is a savior when
    It comes to reviewing for my exams.

  • @user-ue6rk9by1j
    @user-ue6rk9by1j Před 3 lety +7

    Just in time for my quiz later. Thank you.

  • @abhi-wi2mj
    @abhi-wi2mj Před 3 lety +3

    i love mechanisms , its so logical and fun

  • @onelittlestep88
    @onelittlestep88 Před 3 lety

    Thank you Crash Course, you give me something new in this video. XD

  • @believer922
    @believer922 Před 3 lety +3

    Wow 🤩😲very informative video!!!!

  • @bizzarex5275
    @bizzarex5275 Před 3 lety +1

    Thanks for uploading new video.

  • @abhi-wi2mj
    @abhi-wi2mj Před 3 lety

    i love you crash course💚

  • @snowballeffect7812
    @snowballeffect7812 Před 3 lety +8

    This is such an excellent educational tool.

  • @harshgumma8074
    @harshgumma8074 Před rokem +1

    I have a question:
    According to the reaction mechanism isn’t the reverse reaction also possible for all reactions
    Take benzyl chloride for example. We can draw a reaction mechanism for the given reaction
    C6H5CH2Cl + H2O = C6H5CH2OH + HCl
    But we can also do the same for the reverse reaction which is not possible in real life.
    So how do we know if the given reaction mechanism will actually happen?

  • @vikramkc2219
    @vikramkc2219 Před 10 měsíci +2

    Great teacher ❤

  • @nadyahginicecaballero7185

    just in time for my orgchem quiz this friday

  • @benjaminstandefer9015
    @benjaminstandefer9015 Před 3 lety +15

    Thank you for the video. Have you ever considered creating a course oriented more towards mathematics? I am an avid fan of your videos, but often have to turn to other resources for mathematical help.

    • @crashcourse
      @crashcourse  Před 3 lety +26

      Math is definitely a tricky one for us. We've made a couple attempts - Statistics here on this channel & this summer we did Alegbra with ASU. But who knows, maybe down the line we'll try other math coures!
      -NS

  • @henryelicker2403
    @henryelicker2403 Před 3 lety +37

    I wonder what the mechanism is for "Turn the O2 into the O3, dawg".

  • @Rahulshorts124
    @Rahulshorts124 Před 3 lety +2

    Thanks so much

  • @mark_tilltill6664
    @mark_tilltill6664 Před 3 lety

    Really like arrow pushing!

  • @anjanaprabhash.z3031
    @anjanaprabhash.z3031 Před 6 měsíci +1

    Thanks now I get it

  • @jacobkelly677
    @jacobkelly677 Před rokem +2

    Why doesn't the HSO4 negative charge attack the carbocation more readily than the water? Steric hinderance?

  • @Dmplivemail
    @Dmplivemail Před 3 lety +25

    It would be so great if after this classes we had some exercises...

    • @gg3675
      @gg3675 Před 3 lety +6

      If you download the app they have some "notecards" that I've actually found very helpful.

  • @firstmkb
    @firstmkb Před 3 lety

    Excellent presentation, thanks.

  • @ivanmayerle1333
    @ivanmayerle1333 Před 3 lety

    Soooo gooood! Can you show us elimination of N2 form amines (by HNO2) . I thinks that it s very interesting reaction. Good luck

  • @alexisperry4555
    @alexisperry4555 Před rokem

    Wish I had this for orgo 1. I barely passed with a B but im stuck in orgo 2
    Thanks

  • @SciFactsYT118
    @SciFactsYT118 Před 3 lety +85

    Random fact:
    Blue whale tongues can weigh as much as an elephant.

    • @Hambxne
      @Hambxne Před 3 lety +2

      When it comes to pee production, whales are world champs. A single fin whale is thought to produce around 1,000 liters (260 gallons) of urine each day - enough to fill a 10-by-6-foot kiddie pool.

    • @lycaonpictus4433
      @lycaonpictus4433 Před 3 lety +6

      @@Hambxne and i would like to add ...
      And all the water they get is from their food they can't drink sea water
      So it means if they starve they also are dehydrated
      Edit: some species of whales will not eat seasonally , they get the water from their fat stores/blubber
      When you burn fat you get energy
      Which gets converted to heat , co² , and water .

  • @sillypoint2292
    @sillypoint2292 Před 3 lety +3

    I really love organic a lot😘🥰😍

  • @erinaldrich8016
    @erinaldrich8016 Před 3 lety

    When can we expect more episodes?

  • @5ive8ight
    @5ive8ight Před 3 lety +14

    To the person that’s reading this:
    You’re very intelligent and adorable human!
    Stay healthy during quarantine
    My Dream is to have 70k. I been struggling to get there💚

  • @jennadodge6924
    @jennadodge6924 Před rokem +1

    I got most of it but what happened to the HSO4? Why was it not added to the reaction

  • @sillypoint2292
    @sillypoint2292 Před 3 lety +1

    Hey are u from India? I'm from India! Love u guys!

  • @ajay-vlogger
    @ajay-vlogger Před 3 lety

    I can't stop hearing her name again and again. Nice name.

  • @QuestionEverythingButWHY
    @QuestionEverythingButWHY Před 3 lety +4

    “The mind is not a vessel to be filled, but a fire to be kindled.”
    ― Plutarch

  • @whengale
    @whengale Před rokem +2

    The acetylide salt + cyclohexanol reaction is probably occurring in aqueous solution, otherwise the salt wouldn't dissociate, right? So why doesn't the acetylide ion attack the protons in the H2O molecules instead? Is it because the carbonyl's δ+ carbon atom is somehow more electrophilic than the hydrogen atoms in the water? The bonds in water have an electronegativity difference of ~1.2, and the carbonyl double-bond has an electronegativity difference of ~1. So why is it that, in this reaction, water's protons are less attractive to the acetylide ions than the electrophilic carbon in cyclohexanone?

    • @whengale
      @whengale Před rokem

      I understand that water is formally excluded from the first step in the reaction & that this is just a pedagogical proof of concept, but in a real situation, how would I be able to *predict* that the acetylide would attack the δ+ carbon atom instead of one of the *more* δ+ protons in H2O?

    • @whengale
      @whengale Před rokem

      ok I just read on Wikipedia that the reaction is usually done in liquid ammonia, which is a nucleophile & so would not be attacked by the acetylide. I guess I answered my own question lol.

  • @wada-wada
    @wada-wada Před 3 lety

    why do you input an empty line before every line of your subtitles?

  • @aceroro20
    @aceroro20 Před rokem +1

    why is water still floating? i’ve never been able to grasp why it is still there

  • @margaretgodfrey9946
    @margaretgodfrey9946 Před 3 lety +1

    They use my own professor's book for the videos so this really works for my class

  • @BassikMusic
    @BassikMusic Před 3 lety +4

    Ah, the things nightmares are made of

  • @DailyDoseDocumentary
    @DailyDoseDocumentary Před 3 lety +1

    Nice piece.

    • @DailyDoseDocumentary
      @DailyDoseDocumentary Před 3 lety

      Great explanation of Reaction Mechanisms.

    • @DailyDoseDocumentary
      @DailyDoseDocumentary Před 3 lety

      @@FlamingBasketballClub We publish short documentary-style films usually 3-minutes or less Monday - Friday!

  • @ramjayadeepb6861
    @ramjayadeepb6861 Před 3 lety +24

    Corona:"I spread fast"
    Me: "not faster than crash course views"😎

    • @prem5176
      @prem5176 Před 3 lety +2

      Mmmm, no there are many other channels get more views in less time

    • @ramjayadeepb6861
      @ramjayadeepb6861 Před 3 lety +1

      @@prem5176 yup

  • @emacuhara5635
    @emacuhara5635 Před 3 lety

    Yay, app!

  • @getrektfn5725
    @getrektfn5725 Před 3 lety +23

    “Who else is reading comments and not watching in full screen?😂”
    *(Hey CrashCourse thanks for commenting on my new video)❤️*

  • @benrobinett3396
    @benrobinett3396 Před 3 lety +1

    Idk if I’ve ever been this early

  • @franck1919
    @franck1919 Před 3 lety +4

    11:45 I loved the phrase "Don't panic" that makes me remember the cover of Hitchhiker guide to the galaxy book. Like if you read that awesome book. Nice content. Leave my like.

  • @ajay-vlogger
    @ajay-vlogger Před 3 lety

    Ohhhhhhhhhhhhh !!!!! 16th comment I love CrashCourse.

  • @benscrafield9575
    @benscrafield9575 Před 3 lety +4

    A few misleading things in this video. First of all a lot of the structures are not great: molecular geometries were wrong for sulfuric acid and H3O+, and there’s the tendency to show square-planar-type structures for organic molecules - obviously people do this for the purpose of teaching, but then when you want to show a mechanism, e.g. an elimination, you need to introduce another method of representation for it to make sense. Speaking of which, the reversible hydration/dehydration would surely give the E alkene as the major alkene component, very quickly. As presented in the video, it makes it look like you would have a mixture of the Z alkene and the alcohol, which effectively would not be true. Also the reference to pKa was quite odd: why state that the protonated alcohol has a low pKa if it’s not going to be compared to H3O+ in the forward direction?

  • @manaswikumar4969
    @manaswikumar4969 Před rokem

    That warning sign was scary

  • @afrnn
    @afrnn Před 8 měsíci +3

    cant understand a thing 😭😭

  • @QuestionEverythingButWHY
    @QuestionEverythingButWHY Před 3 lety +5

    “Wonder is the seed of knowledge”
    ― Francis Bacon

  • @JS-vv3mo
    @JS-vv3mo Před 3 lety

    in the next video,deboki di plz try to explain the diff. btw inductive ,electromeric,mesomeric n hyperconjugation....really it ll help me a lot...🙏

  • @QuestionEverythingButWHY
    @QuestionEverythingButWHY Před 3 lety +5

    "Be less curious about people and more curious about ideas."
    -- Marie Curie

  • @karlbergen6826
    @karlbergen6826 Před 3 lety

    Organic reactions tend to proceed to give multiple products. Usually one of.the products is a polymeric material often called tar.

  • @sarthakpeepra3748
    @sarthakpeepra3748 Před 3 lety

    can i get a shout out?

  • @haileyhua4468
    @haileyhua4468 Před 3 lety +5

    I hate school

  • @brynwhitehead1731
    @brynwhitehead1731 Před 3 lety

    Hot Mic.
    So, to the business of business.

  • @sebfetea3408
    @sebfetea3408 Před 3 lety

    I am an unreactive mechanism

  • @culwin
    @culwin Před 3 lety +2

    Most people driving don't seem to know what a Yield sign means.

  • @nooraoude1000
    @nooraoude1000 Před rokem +1

    she looks like camilla cabello

  • @mariemartinez7121
    @mariemartinez7121 Před 3 lety

    Me watching their videos from 2013...

  • @angusjulie9701
    @angusjulie9701 Před 3 lety +3

    When will crash course Asian and African history come.

  • @youre_totally_right_but_
    @youre_totally_right_but_ Před 3 lety +1

    27 seconds gang

  • @ZubairAli-ns7vr
    @ZubairAli-ns7vr Před 3 lety

    👍👍👍👍👍👍👍👍👍👍

  • @vaughnjohnson8767
    @vaughnjohnson8767 Před 3 lety +3

    Organic Chemistry explained by Marvel:
    Chemistry: Nucleophilic War
    Chemistry: Endgame

  • @josenellandrewtumulak2400

    Dope

  • @jorgeherrera-uo2pr
    @jorgeherrera-uo2pr Před 3 lety +2

    Diversity!!!! In your hosts we love to see it!!!

  • @justinanderson267
    @justinanderson267 Před 3 lety

    Oy
    You lost me at electrophilic additions of a protein to an alkaline.
    I need to go back over my high school chemistry lol

  • @patrickpowell601
    @patrickpowell601 Před 3 lety +1

    When did science look so damn good 🤤

  • @aryansingh7209
    @aryansingh7209 Před rokem

    When your organic chem teacher doesn't teach you properly!

  • @TheKilerbg
    @TheKilerbg Před 3 lety

    Early birds post the first comments

  • @abdullahmusa9547
    @abdullahmusa9547 Před 3 lety

    Almost First

  • @traceycook7136
    @traceycook7136 Před 3 lety +1

    I thought I was going to finally learn how to drive uggg...

  • @beepk9228
    @beepk9228 Před 3 lety

    Can you guys please bring back Human Geography T_T

  • @Syncronicity888
    @Syncronicity888 Před rokem

    Way over my simple mind.

  • @AInova.2
    @AInova.2 Před 3 lety +1

    Focus on the problem rather focusing on theories in organic chemistry .we need much practice to familiar with OC.

  • @chrisfit
    @chrisfit Před 3 lety +3

    So tired of reaction videos.

  • @ZelenoJabko
    @ZelenoJabko Před 3 lety

    Sorry, you are what?

  • @Spit823
    @Spit823 Před 3 lety +2

    The real life map analogy is so unnecessary. Can’t we just get to the point?