Potential of immunotherapy in MSS metastatic colorectal cancer

David Tougeron, MD, PhD, Poitiers University Hospital, Poitiers, France, highlights the potential of immune checkpoint inhibitors in patients with high immune scores in microsatellite stable (MSS) metastatic colorectal cancer, as demonstrated in the AzetoTRIBE trial (NCT03721653), when combined with chemotherapy. Prognostic biomarkers of immunotherapies range from polymutants to high tumor mutation burden (TMB) in patients. This interview took place at 2024 European Society for Medical Oncology (ESMO) Gastrointestinal Cancers Annual Congress in Munich, Germany.
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