ESC Guidelines: Prescribing ARNI (Arabic Version)

A revolutionary medication for HF patients that needs understanding of its benefits beside its tips and tricks when you prescribe it.
Let's elaborate these points.
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
www.escardio.org/Guidelines/C...
ESC Guidelines: Prescribing ACE-I & ARB (Arabic Version)
• ESC Guidelines: Prescr...
PARADIGM-HF trial, Angiotensin-Neprilysin Inhibition versus Enalapril in Heart Failure
www.nejm.org/doi/full/10.1056...
TRANSITION Study, NT-proBNP Response to Sacubitril/Valsartan in Hospitalized Heart Failure Patients With Reduced Ejection Fraction.
www.jacc.org/doi/abs/10.1016/...

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What are the mechanic of action