Obsessive-Compulsive Disorder Simplified | Neurobiology | Diagnosis | Living with OCD
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- čas přidán 29. 06. 2024
- Michael Ingram, Jr., M.S., M.D. is a board certified psychiatrist who has suffered with OCD. He provides an overview of Obsessive Compulsive Disorder.
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OCD is very strong painful constant impulse with hopelessness, unsatisfactoriness, fearfulness, boringness, anger, tiredness , headache, restlessness, no readiness, withdrawal , and escape. OCD is the fierce mental torture 😭
Sounds like you don't have the ability to compartmentalize emotions from logic. Also, priorities seems to be disproportionate to the severity of the consequences. Like thinking a chain reaction of events will lead to your death for not washing your hands. So what's the difference between me and you? Probably many, but I also believe I could die from not washing my hands. I just am not afraid of that. I think that's highly unlikely, but I'm not going to spend my time dodging what ifs to live.
"He who seeks to preserve his life will lose it, he who seeks to lose his life for my sake will preserve it. "
OCD is BADLY Treated
As somebody with very bad ocd. I needed this and i thank you.
My heart goes out for you brother. God bless
@@joshuafriedman6829 Your reply goes a long way. I also needed that! If you have ocd you know exactly what i mean!
@@JR-fq2eq yes I really do know what you mean. I have ocd, and, well, it's indescribable. Thank God I've been learning about it and treating myself well, but there still is a lot of difficulty nonetheless.
Right now as I'm writing this comment I'm in the midst of an obsession, that just sort of went away. Ok, that's weird, but it was very stressful. Yes I know your pain. I'll be praying
No problem. I hope it made some sense. Many of these mechanisms remain somewhat theoretical but as neuroscience evolves, so will our understanding if this complex disorder!
People with this disorder should have disability, Just because we cant see something it doesnt Mean that doesnt have an effect on People lives, functionality..
Thanks for simpliflying and explaining this disorder. I have ocd and have a family member who also displays symptoms of ocd although not formally diagnosed with it
No problem. I hope it made some sense. Many of these mechanisms remain somewhat theoretical but as neuroscience evolves, so will our understanding if this complex disorder!
Simply pysch edu channel it did make sense except some big words. It will be fascinating for you to learn more about OCD as more research conducted on neurobiology
So well done and clear. Absolutely brilliant! I've been struggling with OCD my whole life (38 years) and it's never gotten clear answers how the OCD works in the brain and also how the medication are working. I'm trying to make a decision on if I want to reduce and after few year quit medicine. This video and your channel is helping me making an informed decision.
cheers from Iceland
Stinni
Thank you so much for your clarity especially at the patient level!
Thank you Dr. Michael. Wish to see you more OCD related videos in the future !
Can’t wait to learn more!
I was previously on Fluvoxamine for OCD, I have it severely (mainly intrusive/irrational thoughts). It worked well- but only 80%. I’m watching this video because I’m too overwhelmed with ocd since ive stopped taking my medicine. It’s interesting to learn why my brain acts the way It does. I had a very bad upbringing- constant change and instability, plus genetic anxiety. Seeing this video has made it more clear that I need to stay on my medicine and get therapy ASAP. Thank you for sharing your knowledge to help us!
was yours harm ocd? like disturbing thoughts of harming others?
@@GeraltOfRivia99 Yes, it was. It was harm ocd, religious ocd, relationship ocd, and Heath ocd. Those were the 4 things i focused on the most
@@junipercedar im in a similar situtation mine are the same problems you had with the intrusive thoughts. i took an ssri years back just like you and it helped. but than it fizzeled out and stopped working so im trying different ssris for it now. i may give
Fluvoxamine a try
Even without medicine only by ERP therapy you can solve ocd if you can control your thoughts and compulsions just by controlling your pre frontal cortex which is behaviour you can cure it completely i cured it in 8 months alone without meds . Just keep working don't worry because it will hyperactivate your amygdala. I have had sucide thought now thinking about it i just laugh after getting cured
Thanks for sharing. I’m on Fluvox but I’m curious how much you took. I’m on a low dose but it doesn’t work so thinking about side effects but still might go up.
Incredibly clear and helpful. Thank you
13:04 Im laughing at the multiple circles emphasizing the loop ... and how it completely represents me x) I'm in the first loop mostly. Anyway, thanks for the dedication in this presentation.
This is great. Thank you for the explanation.
It seems like I get a'lot of my intrusive thoughts when my brain is excited. I was wondering if anyone else has noticed this in themselves.
thanks for this video, very interesting.
you forgot one treatment though "psilocybin interacts with different serotonin receptors in the brain, including those which seem to regulate certain brain regions of individuals with . Treatment with multiple doses of may change the binding activity of serotonin receptors such that symptoms are reduced"
É a segunda vez que eu assisti esse vídeo, para mim, e/ou segundo a minha opinião, e/ou segundo a impressão que eu tive, foi o melhor vídeo que eu assisti, que fala sobre possíveis causas do TOC. Muito obrigado por criarem, e/ou publicarem esse vídeo; eu também tenho TOC, e para mim as vezes é muito difícil, ter que continuar vivendo, sentindo sintomas, como pensamentos intrusivos, rituais mentais, comportamentos, crenças limitantes; esses problemas muitas vezes me atormentam, eu tenho desde os 13 anos de idade, até onde sei, mas só fui diagnósticado com TOC, quando eu tinha 22 anos de idade. Atualmente eu não estou tendo mais, e/ou muita condição de fazer consultas médicas, e sessões com terapeutas, e/ou psicólogas, porque para eu está fazendo, e/ou continuar fazendo eu preciso está gastando muito dinheiro; e no momento eu estou desempregado, o que vocês acham que eu deveria fazer? Suprementos como Triptofano, e N-Acetil-L-Cisteína, podem me ajudar significativamente contra os sintomas do TOC, eu estou tomando triptofano atualmente, e em algumas coisas tem me ajudado um pouco, no passado, um pouco distante, e também próximo, eu também já tomei vitamina D3, Ômega 3; segundo eu pesquisei, a N-Acetil-L-Cisteína pode ajudar direta, e/ou indiretamente a produção de glutamato no cérebro, e se não me engano, pacientes que tomaram suplementos de NAC tiveram pelo menos algumas melhora significativa.
I like that you touched on the relation between OCD and addictive behavior, but I was hoping for more "new" information with the basal ganglia and related excitotoxicity theory possibilities (I know research is limited.) My husband, father, and three male friends (these are just the ones who are professionally diagnosed, I know others who don't have a diagnosis but have the symptoms) have ADHD, OCD, and extreme pain/shakes/tremors. One is a type 1 diabetic.
All are inflammatory disorders, whether as cause or an effect...and all should be treated as such. It makes me wonder about the role of autoimmunity in OCD as well as PANDAS and Huntington's et al.
The problem of treating OCD with therapy and SSRIs is that 1) you can't "outthink" physical pain/sensations and 2) you're not really treating...you're hiding symptoms. It'll do I guess?????
but I want better for my loved ones.
Hi Patricia,
I'm a resident psychiatrist with a special interest in the treatment of OCD and related disorders in Toronto, ON Canada. Treatment with both exposure and response prevention therapy and medication such as SSRIs can actually be extremely effective in inducing a substantial response or even a complete remission of OCD. It truly is a cure for many - it's just a pity that it isn't a cure for all, but that's where work continues with different innovations in the realm of therapy (e.g., Inhibitory Learning, ACT for OCD) and in the realm of psychosurgery (e.g., Magnetic Resonance-guided Focused Ultrasound). I also want better for my patients every day - but what's lovely about working in this space is that so many do actually get significantly better, return to work, become more grounded and present with loved ones, learn to resist their symptoms and turn toward doing what matters to them, etc.
@@rahath1607 There's no such thing as 'remission' of OCD, what you're talking about are OCD symptoms. That's a very sweeping general statement to begin with, but there's a difference between someone's symptoms versus the disorder, getting quantitatively "better."
Exposure therapy is emotional torture, and I hope one day it goes the same way insulin treatment goes. It's barbaric.
Which is why as I said, I want better for my loved ones.
@@Manchessollte421 As someone who has watched people's lives get better with ERP, and having done ERP myself for my own OCD, I think it's colossally unfair to call it emotional torture. It's not. Perhaps with a therapist who barrels through, it would be a very distressing experience, but it can be a major life giver for most patients (except for the very refractory). You may hope that ERP goes the way of insulin therapy some day - that's a luxury that you can afford to muse about. If it goes that way, my patients will suffer - but I guess you'll get to feel better about this crusade of yours while people with OCD lose out on any hope for a life of any quality. They can just go back to thinking OCD has to do with sexual feelings about their mothers and waste years in psychoanalysis...I guess?
@@rahath1607 can I have your contact information ?
How do you get rid of the inflammation in the body?
Have you explored Glutamate and Homocystine? Homocystine locks the Dopamine D3 receptor which influences short term neuro plasticity. Constant stress yields an abnormally high homocystine level in the blood and triggers an OCD storm. I take folic acid and betaine anhydrous
What kind of folic acid? I have ocd as well
I hope no one gets ocd i hope no one...
Best presentation on OCD
Thank u vary much
How u explain that(ocd) is excellent.
N-Acetyl-Cysteine daily helps me a lot. (I am not a doctor. This is not medical advice.)
I underwent Ketamine treatments for OCD and didn't find it very effective. It's usually indicated more for depression. TMS is supposed to be a bit more effective but never tried it. The most effective treatment for me is obviously Klonopin but that isn't a long term or healthy solution.
Very hard mental health disorder to treat.
I don't believe any "specialist" who have never had any sort of OCD himself cant treat this condition effectively. This particular mental disorder you got to know what it's like before helping others.
Thank you 🙏
Of course!
What do you think of Gaba supplements as a prospective treatment for OCD symptomatology, generalized anxiety, insomnia (obviously quite interrelated)? I was prescribed them by a homeopath after seeking natural remedies for my insomnia. I take 1000 mg in the evening. I understand it's supposed to aid by targeting glutamate.
Thank you for your efforts
I wish you make a video without the anatomy and basics the flow is sort of interrupted by naming structures giving them a simile then not talking about their role or saying we'll talk about that later or naming multiple structures before getting into the role I got side tract too many times waiting for some of the labelling to finish
If you give each structure less time as in this is the amygdala it is in x location it does x because it has x that do x which explains x in ocd
Here we have x structure (if it has a significant anatomical relationship to another structure in ocd mention here) it does x because of x we saw this in x it explains x
Regards
I'll just remove my brain and throw it to the trashcan
I use Buspar and it helps along with therapy.
Unfortunately I did TMS for 3 months and it didn’t do anything and possibly made things worse. Now, the same doctor is telling me they have a more “OCD” version of the treatment where before it was more for anxiety/depression. I don’t know but that and Neurofeedback was a huge waste for me. I’m also 15k poorer. If someone else does it I’m not saying it definitely won’t help but both sucked for me.
Sorry to hear that.Good news is anyone can recover from this disorder.Its all about changing your relationship with ocd and seeing that it's not the end of the world with having this disorder and disputing any irrational beliefs you hold about these thoughts.Why is this thought so bad to you?.Is it the actual thought that's the thing that's making you feel distressed or your perception about this thought. Change your perception and believe and suddenly ocd doesn't have a fuel to run off of
Currently i am using fluvoxamine for past 3 month but there is no satisfactory result please suggest me
I just got a nasty concussion and am fairly certain the impact was to this very part of my brain (right below my right eye socket). I have OCD & depression, both of which are treatment-resistant. While I've felt clumsy and stupid since the accident, my mood and anxiety have actually improved noticeably. I am hoping that aspect of the concussion DOESN'T go away. I can't find anything about positive concussion experiences and feel like I'm crazy for even thinking this, but it's undeniable. I'm also a migraine sufferer but haven't had a single migraine after the initial head pain subsided. What is going on here?
I'm no neurobiologist I'm just a CZcams commenter lmao but perhaps you got smacked right in the frontal lobe and it 1. diminished the stimulation of your brain's stress response neurons and 2. That decreased stress has made it easier to do EF/SR tasks
Both of which help diminish your OCD related anxiety and depression
Q. I wonder where on the head you got hit, lol
This may be a simple question; does OCD develop/present itself only after an (initial) excessively stressful life event? If so, why is this the case?
For example, I was an anxious child though I never experienced OCD until I was eleven. This was following several severely stressful life events occurring at once.
Thank you. I also thank you for the video!
Not necessarily always after a stressful life event, some people can have onset of OCD without it. My understanding of this is that stressful life events can trigger psychopathology through those vulnerabilities that were mentioned in the video, i.e., genetics. The reason this doesn't happen to everyone is that not all people will have the same vulnerability factors, but not all people will have to experience stress to trigger it either. Hope this makes sense
I noticed something was stressful in my life at age four. It wasn't environmental though. It was OCD symptoms. As I aged my OCD latched onto other stresses/triggers.
Thank you everyone for your replies - I appreciate it!
I have OCD where there is 2 voices.
One of them is named Phillip, he is like an abusive boyfriend almost, according to him he is 18 years old. It's interested because it's like watching a human being grow and change, it made me think alot about how other people think and change. He is nothing like he was 5 years ago. He has been about for 7 years.
For one when he abuses me he doesn't say "Don't tell mommy and daddy." Anymore.
He just straight up tells me he is fake, he would never do that when I was little.
Phillip likes to hit me and shows me knifes and says that if I cut myself today I would not be depressed.
I am now so depressed that I like pain, I feel like no one understands me and I want to escape this cage. By killing myself.
Jessie is the other one,
She literally has full conversations with my other voice,
They are best friends,
She is like the fire extinguisher to the flame,
She (along with Phillip) is very logical.
She calms me down by telling me to not worry and I am on the right track to success,
According to her she is 11 years old.
They have different times to wake up.
Phillip: 9:00AM 10:00PM
Jessie doesn't wake up at a time,
She could not wake up for days,
Well when Phillip is at his peak of bulling
Jessie comes and stops him from doing anything else.
Phillip is like the ego,
Jessie is like the super ego,
But they can both switch.
If Jessie is 2 parts of the brain then that
Makes alot of since!
Example:
Before switch: "No it's ok you can do this."
After switch: "Yeah you are going to die... Haha..."
I can easy stop Phillip by acting like a resentful teenager. He gets so annoyed by that. XD One moment he says "You are going to die, wait for it." And the next.
"Oh my goodness you are the most terrible teenager I SWEAR!!!!"
I read a report that ocd could be partly caused by a plaque build-up in the Basal Ganglia, similar to what has been seen in patients with Parkinson’s. Do you have any information on that? I have been trying to find that report again.
This is the closest example I could find - if you by plaque build-up perhaps mean calcification?:
jamanetwork.com/journals/jamaneurology/article-abstract/593912
Also maybe these:
www.ncbi.nlm.nih.gov/pmc/articles/PMC4509019/
www.anip.co.in/article.asp?issn=2588-8358;year=2020;volume=4;issue=1;spage=90;epage=93;aulast=Ghogare
neuro.psychiatryonline.org/doi/pdf/10.1176/appi.neuropsych.12090220
Why would glutamatergic agents, eg Ketamine help given that OCD is associated with increased glutamate levels in CFS, caudate and OFC?
This is a great question. Remember that "Glutamatergic" is vague. We know Ketamine is a noncompetitive antagonist of the NMDA glutamate receptor which is the primary ionotropic receptor for glutamate neurotransmission. Recall that NMDA receptors and AMPA receptors (both glutamate receptors) are involved in neural plasticity and learning. Blocking NMDA receptors in certain areas of the brain may decrease glutamate signaling in those areas or could potentiate glutamate signaling downstream depending on the circuit and downstream effects. I think we too often look at the problem as simply too much or too little of a neurotransmitter without appreciating the possibility that increased glutamate levels in OCD patients could be a compensatory increase as a result of chronic hypoactivation rather than the actual cause of OCD behavior. One theory is ketamines ability to enhance synaptic plasticity in certain areas of the brain like the cingulate and/or medial OFC which might partially explain the benefit. The bottom line after this diarrhea of theoretical ideas is that NO ONE actually knows whether the pathophysiology of OCD as we know it now is even true and valid...
@@mtipsychiatry Thanks for your response. Yes it is important not to mistake correlation with causation.
I always appreciate theoretical diarrhoea, thats where testable hypotheses are born.
It seems that the effects of many psychiatric medication are downstream, SSRIs for example. Neuroplasticity seems to always be part of it.
why there's a question mark on title?
I have been suffering from ocd for more than 12 years. I get violent thoughts and sexual thoughts and urges of god. I feel so anxious and get panic attack. I am a Muslim. Please help, thank you
Say a lot of zekr thousands of times sister everyday and you will be cured within a month InshaAllah
@@nicolelarge887 thank you please keep me in your prayers
@@shajiyajahan4202 just say la hawl wala quawat ila bellah لا حول ولا قوة الا بالله and يا حي يا قيوم برحمتك استغيث thousands of times everyday while you walk and while you work. Within one month, you will be free of this! I had this illness for 23 years and I am totally cured because I used to repeat this zekr everyday day thousands of times
@@nicolelarge887 thank you
The same here. I hope you will get better soon.
Which medication is more effective in treating OCD??
Irss. Sertraline, paroxetine, etc. Depends on patient
@@kastorpantalondescocido9272 Anafranil but it has annoying side effects.
If someone need any help when struglee ask me for help. I will try to help you as good as I can. I Said that because I have this disorder on severe type and know almost every type of obasesions and compulsions because I had them and still have...I dont want to say that i am magician or something but I just wanna help.
Cheers from Croatia🤗
Me
Hours of researching and time on articles….and I could’ve just watched a 30m video explaining all the information I was looking for neurologically! 😑🤦🏻♀️😂😅
Wait… with ERP one isn’t supposed to “reason” with the thoughts! I’ve never done it that way because you are then using compulsion to ease the Amygdala. I think you didn’t realize what you were saying here…
Yes and no. I have actually found that reason can play a role in challenging thoughts but you are correct that it can easily become a compulsion. For instance, I have found it helpful to say back to OCD, "I'm not washing my hands for the 10th time because normal people don't do that so why should I?" and "This may be contaminated or maybe it's not. I have no way of knowing for sure but I'm not going to allow myself to be paralyzed with fear. If I get sick then I will then deal with it as others have." and "I know my brain is sending false signals causing me to be afraid as this is part of OCD." This "reasoning" typically provides me with a bump in motivation to resist carrying out compulsions. However, if one is trying to use reason to "prove" that an OCD thought is false, that will absolutely not work. There is no such thing as certainty. However I feel that dealing in probabilities is helpful in determining a course of action.
Can i get the ppt ??
I can't focus on this cuz it's too boring and my ocd is extreme
i m suffering 😭
OK this is all well and good and it seems thay have a better understanding but for most the new treatments all cost money or you have to live we're thay will do it on the NHS witch I find disgusting we are owed better the amount we Suffer I'm currently on cannabis and high doses of anit depresses could u explain why canabis works at taking down the anxsity and compulsions and intrusiveness I don't like to self medicane but have no choice so I buy it illgely but there is a canabis clinic that will give you a mix of thc and cbd canabis flower tailored to your needs but thay won't obscene amount of money people should be able to get it on the NHS we are ill we get not enough money as it is and thay expect us to pay 100s a month let alone trying to feed are self's did I arks for this condition no did I arks for the suffering no at lest thay can do is give us effective treatments for a low cost or free it's like TMS thay won't 1300 per 10 session and I don't even no if that works
Isn't this supposed to be simplified?
If the caudate is diaable in stoping toughts , there Will not be any psicology who can help you