FiO2 PEEP Table | Medvarsity

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At the start of mechanical ventilation, the most important priority is to provide effective oxygenation. To ensure the patient's safety following intubation, the FIO2 should always be set to 100% until adequate arterial oxygenation is documented.
A brief period with a FIO2 of 100 percent is not harmful to the patient receiving mechanical ventilation and provides several advantages to the clinician. Positive End-Expiratory Pressure (PEEP) is used to prevent the end-expiratory collapse of diseased pulmonary areas in order to reverse severe hypoxemia caused by pulmonary shunting, which is a defining feature of Acute Respiratory Distress Syndrome (ARDS).
Trans-pulmonary pressures of around 10 cm H2O are sufficient to keep the lung open at end-expiration in the presence of a normal surfactant. If the surfactant's tensioactive properties are compromised, trans-pulmonary bronchioloalveolar opening pressures can reach 25 cm H2O.
Dr. Raymond Dominic Savio, emphasizes on everything you need to know about initial fraction of inspired oxygen (FiO2), and positive End-Expiratory Pressure (PEEP) with FiO2 PEEP table, high vs low PEEP.