Premature rupture of membranes

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  • čas přidán 27. 07. 2024
  • This is a brief video on premature rupture of membranes, or the leakage of amniotic fluid before labor.
    I created this presentation with Google Slides.
    Images were created or taken from Wikimedia Commons
    I created this video with the CZcams Video Editor.
    ADDITIONAL TAGS:
    Premature rupture
    of membranes
    10-week-old human fetus surrounded by amniotic fluid and fetal membranes
    By drsuparna www.flickr.com/photos/74896762... - www.flickr.com/photos/74896762..., CC BY-SA 2.0, commons.wikimedia.org/w/index...
    Leakage of amniotic fluid before labor
    Overview
    Risk factors and causes
    Diagnosis
    Management
    Chorio-
    amnionitis
    PROM = premature rupture of membranes
    Amniotic sac rupture / fluid spillage more than one hour before onset of labor
    Labor = regular contractions + cervical change
    PPROM = preterm premature rupture of membranes
    Amniotic sac rupture before 37 weeks
    Prolonged rupture of membranes
    Amniotic sac rupture for longer than 18 hours before delivery
    “Gush of fluid†vs steady leakage of fluid
    Note color and consistency of fluid
    Thick vs watery
    Clear, cloudy, meconium, blood-tinged
    Overview
    Overview
    Risk factors and causes
    Diagnosis
    Management
    Chorio-
    amnionitis
    Vaginal or cervical infections: UTIs, STIs, bacterial vaginosis
    Smoking or drug use during pregnancy
    PROM or preterm deliveries in previous pregnancies
    Nutritional deficiencies; underweight mothers
    Polyhydramnios (too much amniotic fluid)
    Multiple gestation
    Cervical insufficiency (short or prematurely dilated cervix)
    Invasive procedures (amniocentesis, cerclage, etc)
    Pathophysiology:
    Weak fetal membranes
    Infections (sometimes subclinical)
    Genetics
    Risk factors and causes
    Overview
    Risk factors and causes
    Diagnosis
    Management
    Chorio-
    amnionitis
    Three classic tests
    Pooling: Collection of fluid in the vagina (posterior fornix)
    Nitrazine: Neutral fluid turns nitrazine paper blue; vaginal fluid usually acidic. Amniotic fluid is mildly acidic → blue nitrazine paper
    False positives: blood, semen, infections, antiseptics, lubricant
    Ferning: Dry amniotic fluid on glass slide has crystallization pattern called arborization that resembles fern plant on light microscopy
    Ultrasound can detect low levels of fluid (low residual fluid levels)
    Other new tests detect chemicals or proteins in amniotic fluid
    By Paul_012 - originally posted to Flickr as Positive fern test, CC BY-SA 2.0, commons.wikimedia.org/w/index...
    Management
    Overview
    Risk factors and causes
    Diagnosis
    Management
    Chorio-
    amnionitis
    Previable
    24 weeks
    Watchful waiting; no tocolytics, steroids, MgSO4, or abx
    Induction of labor to end pregnancy
    Preterm
    24-33 weeks
    Tocolytics to prevent labor; steroids twice 24 hrs apart for lung maturity; MgSO4 as tocolytic while lungs mature; abx for GBS prevention
    Amnioinfusion to replace lost fluid is controversial
    Late preterm
    34-36 weeks
    Induce labor; abx for GBS prevention
    Term
    37 weeks
    Induce labor; abx for GBS prevention
    Definition: infection of chorion, amnion, and/or amniotic fluid surrounding fetus
    Diagnosis:
    Signs and symptoms: fever, rupture of membranes, leakage of fluid, uterine tenderness, elevated maternal heart rate ( 100 bpm), elevated fetal heart rate (160 bpm)
    Fever: exclude maternal URI and UTI
    Labs: increased white count ( 15,000 cells/mm³)
    Treat with ampicillin, gentamicin, and clindamycin
    Induce delivery
    Covers gram negatives and anaerobes
    Afebrile for 24 hours
    Chorioamnionitis
    Overview
    Risk factors and causes
    Diagnosis
    Management
    Chorio-
    amnionitis
    By Nephron - Own work, CC BY-SA 3.0, commons.wikimedia.org/w/index...

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