How to Identify Molecules - Proton NMR: Crash Course Organic Chemistry #26

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  • čas přidán 20. 08. 2024
  • If you were given a chemical and told to identify it, how would you go about doing that? You could look at different factors like color, boiling point, melting point, or smell, but the answer still might not be clear. Thankfully, today we have a more precise, higher-tech way of identifying chemicals called Nuclear Magnetic Resonance, or NMR. In this episode of Crash Course Organic Chemistry, we’ll look at how NMR allows us to visualize a molecule as a spectrum, and what the peaks on the spectrum tell us about the structure of the molecule.
    Episode Sources:
    Mahdi, J. G. (2010). Medicinal potential of willow: A chemical perspective of aspirin discovery. Journal of Saudi Chemical Society, 14(3), 317-322.
    Dempsey, D.A., Klessig, D.F. How does the multifaceted plant hormone salicylic acid combat disease in plants and are similar mechanisms utilized in humans?. BMC Biol 15, 23 (2017). doi.org/10.118...
    Still, W. C., Kahn, M., & Mitra, A. (1978). Rapid chromatographic technique for preparative separations with moderate resolution. The Journal of Organic Chemistry, 43(14), 2923-2925.
    Pastre, J. C., & Duarte Correia, C. R. (2006). Efficient Heck arylations of cyclic and acyclic acrylate derivatives using arenediazonium tetrafluoroborates. A new synthesis of the antidepressant drug (±)-Paroxetine. Organic letters, 8(8), 1657-1660.
    Series Sources:
    Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
    Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
    Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
    Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
    Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
    Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
    McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
    Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
    Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.
    ***
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Komentáře • 58

  • @Slinder14
    @Slinder14 Před 3 lety +80

    I really need all these spectroscopy videos to start being pumped out. This playlist has helped me so much with OCHEM this semester!

  • @kendalldoer5466
    @kendalldoer5466 Před 3 lety +38

    I suspect this will soon become a very popular video and this comment will be lost to the sands of time...

  • @cheezmuffintv1755
    @cheezmuffintv1755 Před 3 lety +33

    SUGGESTION:
    Dear Crash Course Production Team,
    One major reason I prefer your video series over the literally hundreds of others (other than a systematic approach and production quality) is because it provides background to the subject, which help clarify the quirks in it (eg, conventional current vs electron flow). I feel such stories of the modern versions of the subject, perhaps as a supplemental video can help us further understand what all we do, don't and can know, as well as inspire students to investigate certain lines of ideas.
    Tl;dr- Great channel. Love cuz of background the stories provide. Maybe add similar stories of modern understanding and research?

    • @cheezmuffintv1755
      @cheezmuffintv1755 Před 3 lety +1

      @@larkdavis8896 is.. is this a puzzle?

    • @crashcourse
      @crashcourse  Před 3 lety +4

      no, sorry that was a response from a fake account! clearing those out now!

  • @WaltRBuck
    @WaltRBuck Před 3 lety +20

    NMR is one of my favorite things, and one of the things I'm absolutely bad at. I love testing the chemicals I make. I love testing them for purity too. Gas Chromatography is also fun.

    • @WaltRBuck
      @WaltRBuck Před 3 lety +1

      @@larkdavis8896 Funny, I just realized how.. questionable my statement was.. I love working with benzene more than most things, but... only in a legal manner.

  • @nathanturner5884
    @nathanturner5884 Před 3 lety +31

    Alphonse Elric in the background at the beginning 👀

  • @underdogg8240
    @underdogg8240 Před rokem +8

    This is absolutely awesome - well-made, clear and concise. Thank you so much

  • @kindlez98
    @kindlez98 Před 3 lety +27

    Great video, I believe you should have mentioned how to calculate unsaturation on a molecule it can really help

  • @maxmuenchow
    @maxmuenchow Před 3 lety +6

    This was such a great easy to understand explanation and a great example. Thank you very much :)

  • @morcir.174
    @morcir.174 Před 3 lety +5

    Omg this video helped a bit. Nobody told us how to identify molecules and our prof gave us a spectrum with a C15H14O2 molecule to identify. Like thx man but how do I do this?

  • @johnwielding5151
    @johnwielding5151 Před 3 lety +5

    Your unique dedication to this here endeavor is a blessing and an invaluable resource to the world of science. Your aid will enable the youth to discover their potential toward our live's work.

  • @Xnibblet
    @Xnibblet Před 3 lety +6

    A little too quick for my understanding, but great information.

  • @steelformrarity4590
    @steelformrarity4590 Před 3 lety +1

    Boy am I glad I passed organic chem with an A first time I couldn't go through that again, never again...

  • @youraveragepepa1357
    @youraveragepepa1357 Před 3 lety +4

    great lesson!

  • @sturmey
    @sturmey Před 3 lety +4

    Beautifully explained. I little bit of pause after the more complex concepts would allow following things more easily.
    I guess you want to make the video compact, which is also important... But maybe just 3 seconds would help. I guess I can just pause it myself and replay several times as I have been doing haha. But is a bit stressful

  • @wbedard
    @wbedard Před 3 lety +3

    I'll bet that is some expensive solvent. It's also probably not possible to "reuse, reduce, recycle" it, either!

  • @cameronfouche5743
    @cameronfouche5743 Před 3 lety +3

    Are you guys eventually gonna do a video about aromatics?

  • @XxKiokoxX
    @XxKiokoxX Před 3 lety

    WHAT ARE THE ODDS. A client wants a H NMR and I really not familiar with the equipment and you make this video. Wow

  • @quantum2233
    @quantum2233 Před 3 lety +1

    Nice vid

  • @FRACTIONID
    @FRACTIONID Před 3 lety +1

    Thats nice video 👍 🇲🇨

  • @Chem_Gal
    @Chem_Gal Před 3 lety

    right in time for my exam thanks

  • @user-hj7db3dl5w
    @user-hj7db3dl5w Před 3 lety

    Excellent, marvelous... Thanks

  • @kocengineering769
    @kocengineering769 Před 3 lety +2

    Thanks mam
    U know I was dying for Ur next episode OMG
    The time which takes waiting is very crucial to everyone in their life
    Thanks again
    Yes mam Schrodinger's equation is wierd

  • @user-so5lr9mc2p
    @user-so5lr9mc2p Před 3 lety

    Thanks great lesson

  • @khalliwalli-obaidfarooqui

    Thank you

  • @leonardocanada98
    @leonardocanada98 Před 3 lety

    Thank you for explanation this is very helpful.

    • @leonardocanada98
      @leonardocanada98 Před 3 lety

      Can you please help me what is existential psychoanalytic theory theory? Hope you anwer it.

  • @fergimedia
    @fergimedia Před 3 lety +1

    Such great info , awesome lesson ...
    Love these videos ; from Winnipeg, Manitoba, Canada 😃

    • @fergimedia
      @fergimedia Před 3 lety

      @@larkdavis8896 anytime !!!!! You’re doing us’ the huge courtesy “favour” of putting together these videos 😊
      Thank you ☺️ .

  • @akamprayerimonin5347
    @akamprayerimonin5347 Před 3 lety

    I love crash course .who doesn't? 😁💖

  • @sharaiahjoseph6418
    @sharaiahjoseph6418 Před 3 lety

    Fortunately we've moved on to a much high-tech analyticel technique
    Me : and safe

  • @unclebobo6030
    @unclebobo6030 Před 3 lety

    Hi how’s it going watching from broomfield Colorado

  • @mayanksolanki7028
    @mayanksolanki7028 Před 3 lety

    Hey, Is there no crash course available on Mathematics specially..??

  • @imbaZarkout
    @imbaZarkout Před 3 lety +1

    Das the stuff

  • @patrickmeehan6856
    @patrickmeehan6856 Před 3 lety +1

    1:40 "weird quantum mechanical things"
    but she repeats herself

    • @howardbrandon11
      @howardbrandon11 Před 3 lety +1

      "If you think you understand quantum mechanics, you don't understand quantum mechanics."

  • @chinmaykotkar8456
    @chinmaykotkar8456 Před 3 lety

    Please upload videos early...

  • @mattmarzula
    @mattmarzula Před 3 lety

    I just use paper chromatography and reference the chart... Way cheaper and requires no special equipment or licensing.

  • @mathsandsciencechannel

    wait,wait,wait,wait!!! You cant miss the maths and science tutorials,hurry and check it out student. thanks

  • @twothreebravo
    @twothreebravo Před 3 lety

    Reactions & Ire has entered the chat and found...tar.

  • @abdulwaseh3259
    @abdulwaseh3259 Před 3 lety

    MOM chloride :D :D

  • @najdat-hh6653
    @najdat-hh6653 Před 3 lety

    Can you please translate this to Arabic

  • @fernandovillarreal6207
    @fernandovillarreal6207 Před 3 lety +1

    Hu

  • @FundamentalRaps
    @FundamentalRaps Před 3 lety

    Great video! Love you guys!! Id love to collaberate with you one day!! My channel Fundamental Raps turns educational topics into hip-hop songs! I have a great one on chemistry!!

  • @kaylculus
    @kaylculus Před 3 lety

    Early

  • @sickwidit213187
    @sickwidit213187 Před 3 lety +2

    Did you just assume that molecules identity???

  • @sakanibluu
    @sakanibluu Před 3 lety +1

    Im 3rd so go follow SAKANI BLUU plzzz!