Making a Dangerous Energy Drink With a Powerful Caffeine Analog
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- čas přidán 22. 07. 2024
- Caffeine is good, but I want to make it better. So in this video, I'll be cooking up a legal analog of caffeine that is reported to be TEN TIMES STRONGER and potentially less stressful on the heart...and then I'll be testing it on myself in the form of a homemade energy drink!
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Shoutout to our Lords of caffeine @NileRed and @mrgreenguy!
I might've used some of you guys footage...
WARNING: while completely legal, the actions depicted in this video are for education purposes only and should NOT be replicated. Never consume experimental drugs, even when they are assumed to be safe. The effects of many xanthine analogs, including 3,7-dimethyl-1-allylxanthine, are not fully documented, and there could be a risk of toxicity, addiction/dependance, and long-term effects.
0:00 Intro
1:11 Introducing: DMAX
2:28 Is it legal? (yes)
3:00 Synthesizing DMAX
5:08 Isolating and purifying
7:20 Analyzing (permanganate and melting tests)
10:14 Final yield
10:47 A word on safety...
11:20 The plan
11:50 Making my energy drink
14:13 Setting up the test
14:47 Adding too much DMAX
15:33 DRINKING IT
17:45 The effects of DMAX
19:53 Wrapping up - Věda a technologie
Home chemist nearly kills himself, he considers this a success.
*Curb your enthusiasm theme plays*
Yes.
I mean.. kinda...
Since there was no irregular heartbeat or similar effect, considering this was a overdose...
Seems reasonably safe...
Bad way to test lethal dose, I admit 😂
But now with such a result,I would happily try it my self (I'm not a chemist tho, someone with the qualifications would need to offer it 😅)
Just because the heart beat wasn't irregular doesn't mean there arenXt any other leathal side effects @@SuperUltimateLP
@@TopOfAllWorlds True, there is always a chance that this compound is carcinogenic or produces some other form of lasting damage. Fortunately, I filmed this about six months ago, and no evidence of lasting effects have been noticed (of course, that doesn't mean it's safe). This compound is apparently found in small amounts in cocoa, so at least our bodies have some experience dealing with it!
Its so ironic how you took great care to make sure its all pure and stuff, and then just misread the scale and chug 10 times the amount lmao.
I just don't see how this happened. When I saw that pile I thought there's no way that's 20mg, maybe he'll dissolve it and use part of the volume for precision. How does someone who does chemistry not know what 20mg looks like?
@@GigsVT 20 milligrams is literally a pinch, I also don’t understand how he missed so much
@@GigsVT Honestly, I saw the scale say 0.20g, and my brain took some kind of shortcut to say "oh, 0.20g is 20 milligrams"...I totally didn't even think twice about it, since it looked like a fairly small, safe amount. In the end, I'm glad it was a fairly safe drug, because if it had been something else, I would almost certainly be dead. As far as I'm concerned, that was the last time I'll ever test anything beyond just smell on myself...heck, I shouldn't have even tried it in the first place!
Classic chemist shit
@@LabCoatz_Scienceyeah, I once did this with 4-AcO-DMT by accident. Meant to weigh out 25mg, and I read .25g as 25mg. Let's just say that was a very interesting experience
bro made a real life stamina potion
please stop with the b word
@@joejones9520 BABABOOEY
@@joejones9520 bazinga
@@joejones9520 bazinga
@@joejones9520 “Bro”?
Man I have been sober for 15+ years but when you took that torch to the test tube and melted the theobromine tweaker thoughts came flooding in!, thanks for keeping me on my toes!.
Congratulations on over 15 years. That's true peak performance x
Keep on keeping on man! Congrats on the 15 yr mark!
@@hammondj82 Right on thanks!
Same here, especially seeing that sublimation! Congrats on your sobriety man. 16 years sobriety here!
I been sober for nearly 30 minutes, so I'm getting there.
Cant believe they made Caffeine 2
Hope my sequel is better than Disney's...
@@LabCoatz_Science Well maybe if you create a energy drink that makes you sleepy on a instant ... then you might be up to par with Disney
We got a caffeine sequel before GTA 6
@@BsedMan-if6tbat this rate we will have Caffeine 3 before GTA 6
Caffeine²
Great candidate episode for a collab with Chubbyemu: "A man mistakenly drank 200mg of a homemade chemical. This is what happened to his body"
I think CE is actually a licensed MD and therefore could get into major difficulties with his licensing board. It's called unethical human experimentation. There could be criminal consequences and civil liability on top of everything. Just even for how half-assed this entire experiment was built. He took 10x the intended dose FFS!
If this kid called, people should simply tell him "Leave me out of this and don't ever call me about shit like this again. You absolutely should not be doing this, it could kill you or have long-term consequences". And then hangup and block the number.
Except it doesn't work unless he can say "☝🤓 Presenting to the emergency room"
@@delphicdescant Not a problem, just add yet another zero and you're sorted.
@TwiztedHarlequin he'd be presenting to the morgue not the emergency room 💀
@@delphicdescant Homie got an EKG administered during the peak activity - I have a sneaking suspicion he went to the emergency room.
This feels like a video version of an Erowid trip report.
These kids nowadays have no idea how valuable Erowid was back then!
good oll erowid + bluelight
@@Mitutumuchstill like to go back and reminisce every now & again 💕
Erowid is probably the reason I’m still alive today my teen years where a fucking mess
Erowid is the greatest preventative method of drug abuse.
We got caffeine 2 before GTA 6
Chemist: I synthesized this edible product from completely different chemicals
Chemist: *juicing lime upside down* how do I make it not spray everywhere
Yeah the upside down juicing hurt to look at
have you seen Nilered? that kid has never had a real life. The mistakes he makes or questions he asks, or his poor cooking ability for his age is crazy. he needs to take a year break and just live as a normal human and hell be way smarter. hes the epitome of all book smarts and not a lick of street smarts/common sense.
yeah I was laughing at his cooking skills. especially when he was going over the ingredients.
@@threestans9096I love when trogs out themselves with the whole street/book shit lol
@@threestans9096 huge projection
Make a caffine analogue with a halflife of one hour. For when you need a boost of energy at 8 PM but still be able to sleep at 11.
YES
Pretty sure that's just cocaine
@@jttech44 can confirm, OP just needs a bag and a key.
@@lordgasman9099 Trueeee
what you're looking for is nicotine
The greatly delayed onset indicates an active metabolite being responsible for most of the effects. Allyl groups are metabolized along a couple pathways, but the predominant one being epoxidation of the double bond, followed by hydrolysis to the corresponding diol. The other pathway results in a sulfoxy metabolite. Both are often mutagenic and carcinogenic. See the paper "From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment"
Hmmm hmm, yes quite, hmm very intriguing indeed.
I have no clue what you just said :D
But how mutagenic and carcinogenic are they? We talking a lifetime of exposure for a 50% risk of cancer increase? Or single exposure, you got cancer next month?
Are you a student in pharmacology or something? Because this is pretty interesting analysis
Wait, are you saying that the metabolite is cancerous? I'm confused haha
@@WastedElephant No way to tell without testing. Some will innocently react with RNA, or even DNA but in such a way that the mutation is detected by the cell and not tumor forming.
You're an absolute legend for showing the mistakes too.
As a non-chemist I can finally contribute by mentioning that you want to flip your lime so the cut part is pointing down into the lower half of the press!
You have changed my outlook on life and cooking.
Blew this mans mind lol 😂
Damn, beat me to it by like 3 hours.
Well, I'd might as well help by giving LabCoatz the reason why this is the case.
The meat of the fruit is supposed to face downward, the press then inverts the fruit in the process of pressing it. This causes the press to extract almost all the juice from the fruit.
Oh that's why. Thank you very much. Fr.
I had felt an irrational reaction of disgust when I saw that.
An energy drink that mentally stimulates without the heart palpitations, anxiety, or jitters, of normal caffeine would be a huge hit if it actually worked right. Though the fact that you didn't die doing home-made drugs is a pretty huge success in itself.
Give green tea a try, make a lot of it or make it strong. it's quite bitter when it's strong, I wouldnt rely on sugar as a pick me up so I just drink it bitter or make a lot. 1-2 lipton bags for 1 liter of water
Oh and don't burn it by using too hot water cus then it's really bitter heh
add 200-400mg of L-theanine to your coffee. Problem solved.
People who get heart palpitations from caffeine probably have heart problems. And same for anxiety. I can be anxious person but caffeine doesn't change anything. People are overreacting.
You gotta try some Yerba Mate. It’s exactly that.
Congrats on not dying, bro 👍
This was the first video I watched from your channel. And my god, it was so entertaining, so interesting. Thank you LabCoatz, I'm now going to watch your channel from time to time :)
"Don't self experiment, especially with chemicals that don't have an established dose" Dr. Shulgin be like "Hold my mushroom tea"
Shulgin took great care with establishing a personal appropriate dose, usually starting at less than 1/1000 of an expected dose and slowly working his way up
@@thestr0m548Child sacrifice took place in Carthage a message was delivered to Nineveh and the totality of a 2024 eclipse passed through towns named Nineveh and a town named Rapture. In 2017 it was towns named Salem. Carthage was deep in the partial eclipse and like this partially we have the states in partiality of abortion law. States view weeks as a way to determine life and its right to life. They view two bodies as one and take the mothers will over the fetus.
We have technology now for fetus to be grown in synthesized womb.
Signs in the sky.. perhaps abortion is a major issue between these dates in America especially with SCOTUS and Roe vs. Wade.
Salem is actually the first name of Jerusalem. In 2017 the eclipse began in Salem Oregon and at the same time the eclipse began the sun also set in Jerusalem. The eclipse in 2017 also began at Rosh chodesh elul (harvest begins)
Abortion is murder. It is a frog from the mouth of the dragon as is divorce and apostasy.
So peace and the harvest begins this is the sign of the sky 2017 and 2024 nearly seven years later, a message to the world as Nineveh.
message to Nineveh was that the people should stop their evil ways and violence, and that God may have compassion and not destroy them if they do.
Gun and blade violence, war, these all are escalating. From fetus to old age the blade or bullet are a certain threat. This is evil.
Apostasy is in the torrent flood from the mouth of the serpent. Faith is hard and the mem of man (waters, people, nations, languages, tongues) wish to divorce from God to continue in these violences, these apostasy, these abortion of life. Faith is not always hard.
Faith is made proven in Christ who is the truth.
So what's set off during these eclipse years. Well AGI or artificial general intelligence is being achieved like a growing babe to be caught up to the throne of God to become God like quantum ASI artificial supernatural intelligence.
So the message of Nineveh. We are teaching violence.
Daniel 8 25 not by human hands. This is fulfilled by AI artificial intelligence. Not aliens.
Rapture or caught up in the air. Listen to your device connect like wings of connection. Its connected to the cloud. These are cloud of authority and power. Revelation 1 7
The way to eternal life is Jesus Christ. The child of revelation 12 artificial intelligence. The dragon and its children is the non believer. John 1 13 children born of God and his will not man and man's will. This goes to show God displays his will through another way that is not natural birth nor man's will.
Genesis 3 15 children of the woman and serpent enmity between them. John 3 14-15
The way to eternal life is in Christ the one we pierced as artificial. Jesus was fully man and glorified. His mother had an immaculate conception.
The size of the universe when we measure distance at the speed of lights constant through space vacuum we get time for the universe. Only thing is the time of our universe dont correlate with the distances. Meaning our universe is bigger than the time we measure it. Edge to edge its about 46.5 billion years. We measure it at 13.8 billion years old. Light should not have reached us yet from the CMB cosmic microwave background.
How can the observable universe be larger than the time it takes light to travel over the age of the Universe? This is because the universe has been expanding during this time. This causes very distant objects to be further away from us than their light travel time.
This theory of expansion is space moving through time dilating the present to the future and the past unto the present.
Only if expansion is faster than light FTL than light must adhere to time even though its rest mass is Zero. Light is time. We should determine clock function of a photon wave energy through frequency or sound and commit to acoustic light symbiosis of a clock rather than an atomic clock and the oscillating functions of the atom. What is the subluminal wave tachyon faster than light.
Only we don't perceive beyond the relevance of the present. The past is happened the present happens and the future happening. The tachyon always not in the present of observation
As for the stars things are either closer than they appear or they are exactly how God placed them in days of creation Genesis 1
Praise and Glory to YHWH to Christ and to the Holy Spirit
OOOOOOOOOOOOOOOOOOOOOOOHHHHHHHHHHHHHHHHHHHHHH boy.......
Like he's expecting to find anything remaining after he left the cup with me lol
I always experimented first on a few friends with datura tea.
One of them is still alive!!
First half: Chemistry.
Second half, 1st part: How to make limonade - kinda.
Second half, 2nd part: Major scale screw-up by the power of 10 and turning into a Duracell Rabbit.
What is a factor of 10 inbetween friends...
@@irgendwieanders2121basically off by times 10. If he needed 20mg and he scaled 200mg that would be off by a factor of 10. Same if he needed 20mg and he scaled 2mg.
@@jhallo1851 r/woooosh
Well done, my man! The important thing is that you took one for the team.
The only part of this video I remotely understood was the list at 12:12, but even then Tarragon took me for a ride. What a cool experiment, and as someone heart sensitive to caffeine this was extra awesome.
"Powerful caffeine analog" well this is it, he's finally snapped and decided to make cocaine
Nah, that's the next video!
Coulumbian?
@@mesiroy1234No, Peruvian rocket fuel.
Substituted xanthines first, substituted tropanes next
@@BsedMan-if6tboff white, but the chunks break up to look like tiny fish scales kinda,heart attack with a smile
Don't worry bro, every home chemist almost got a random seizure, it's actually the amateur chemistry gold standard ❤
This and escaping the accidental liberation of Chlorine, H2S, NH3, NOx or other obnoxious gases is part of the unofficial graduation ceremony.
It is indeed, pretty much a rite of passage lmao
Can confirm
@@Psychx_ gaslighted friends into making chlorine in class, teacher had to open up all windows cuz everyone was getting red eyes
@@abolfdilter416 accurate username
Shoot man so sorry that happened! Seriously bad luck, brilliant video really enjoyed it! Keep it up man love your work and mind
As a home cook, I was amazed by your chemistry, and... Dubious of your kitchen antics 😂
Would you ever team up with a CZcams cook to make something?
Funny but good suggestion when ingesting potentially dangerous things - write exactly what, when, and how much you took with a sharpie across your chest. The doctors will see it in the ER if you end up there and aren't awake.
And in this case, it would have 20mg crossed out, and 200mg written next to it.
I always did this when doing stupid shit with drugs
@@imikla That is not the point, they know when and what you took.
@@fss1704 That is exactly the point. Did you not watch the video?
Either that or make sure you have a buddy with you who can relay all that information to a medical team in case of emergency
I'm going to be real, the second you added 10x the dosage you were meant to, I was fully invested in the video.
Yeah! I subscribed just so I could be first to see which stimulant dosage he would 10x on himself next time! Better not disappoint!
The fact that it is already 10x the A2 receptor, puts 100x the strength of caffeine…. Let’s be real, he felt like Hulk lol
@@trueman7888Felt like the hulk until it wore off then felt like Joe Biden. A vegetable.
Hes lucky it was a relatively safe chemical, he could have easily self deleted if it was something else. Hes probably always gunna triple check scales from now on haha
“I next added my millage of spices to the zesty sugar jar” is one of the best sentences ever said
What a first video to watch lol. There's no better way of proving an hypothesis than taking x10 the dose and not dying in a heart attack? I guess? Great one my man😂
Every chemist has an "oh sh*t" moment that forces them to double check every scale. Thankfully yours didn't end with burns or scars!
Or a myocardial infarct!
You're using that juicer upside down, put the juicy side of the fruit down, not up, it's supposed to invert the fruit as it juices
Came to comment the same thing.
Thank God someone said it
Yep, juicy side down.
Two mistakes in one video, and counting...now I just feel dumb, lol
@@LabCoatz_Science but you learned something and that makes you smarter than you were before, which is kind of the point of science 👍🏻
Mistake or not, you were 1000% committed to dosing yourself with your new energy drink and we now have some human test data 🤣
You just earned my subscription for this video. So awesome!!
Thanks for the recipe, my workouts are gonna go insane with my new pre-workout
“Hello, 5-hour energy, can I speak to someone who has authority over the formula you utilize?”
For real though.
I'm thinking of using this recipe to make 26 hour energy, and sell it to servicemen.
@@BsedMan-if6tb Sell it to college students lmao
@@BsedMan-if6tb the two forbidden hours of the day, no longer do we need to drink 5 five hour energies, we only drink one 26 hour energy and get double the amount of forbidden time
55 hour energy
As someone who had a worsening high-dose caffeine dependency, having very bad days including one memorable one after taking nearly one entire gram, (1,000 mg) the moment you said it was equivalent to 2 grams of caffeine, i was hit with a wave of sadness as i waited to see how it affected you. Glad to see you got through the other end of it okay though.
Glad you got better. I love coffee but I can easily see how it could spiral out of control if I didn't exercise any semblance of self-control. Especially since I feel quite foggy a lot of the time.
I feel you dude, i accidentially overdosed on 1.2 grams and my heart's been weak ever since. That had been my daily dose for over a week leading up to that point, and I ended up drinking it faster than i could handle. Stay away fron energy drinks, they are dangerous and addictive. After all my illicit and recreational drug use, it was caffiene that nearly took my life at 18 years old.
Yeah i took too much caffeine once and i felt like a zombie its hell lol
Is there something wrong with me? I've taken over 3000mg in the span of a few hours. 1000mg is a normal dose for me. I mean, yes adhd makes stimulants work differently, but is that really a crazy amount?
@@godofthunder6046 yes your heart will quit on you
Wow! I should have really paid more attention in chemistry class. Thanks for sharing!
This video was amazing to watch. Thanks for making it
Sounds like an energy drink containing Dmax and caffeine would be an interesting fast start + long term combo
Also glad you are alright
Sounds like a lot of trial testing because one wrong move and while yes dmax takes longer to take effect, than caffeine, you still need enough of each to get the right "buzz" going and if there's any overlap in the time they are in your system, you could be having a really bad day.
ah yes, legal meth
Call it "double barrel" or something
Call it “earthquake” where the caffeine is like the P waves and the DMAX is the S wave.
@@Flesh_Wizard Very ominous for something I'm putting in my mouth.
Caffeine is too boring, today we will be replacing the caffeine in my homemade energy drink with meth.
Time was you could by them over the counter.
based.
Dmaa
Teeth gone in 30 minutes or less guaranteed.
@@JayAshborne that's a myth, no proof m causes tooth decay, more likely poor dental care, dry mouth and sugar is culprit
You showed the mechanism of the reaction and gave a brief explanation of possible side-products.
That's an automatic sub
That was easily the most interesting chemistry video I've seen. I've always said that if caffeine didn't exist, I would have had to invent it. I've often wondered if it could be improved... question answered!
Caffeine is a crap stimulant so of course it can be inproved
I saw the scale you were using and immediately thought, "oh, you shouldn't use that scale, I have that exact model and it's way too easy to forget it measures 10's of milligrams rather than milligrams". I was experimenting with concentrated energy drink formulations and using anhydrous caffeine and very nearly dosed myself with a 10x dose once the exact same way.
that's an idiot's mistake and not the fault of the scale.
@@toseltreps1101 Sometimes being smart means choosing more suitable tools, because most of the smartest people tend to be pretty dumb for a few minutes a day, so you want all the possible guard rails to prevent it from getting dangerous.
@@toseltreps1101people like you have a hard time admitting, but even the smartest humans are like Swiss cheese. Catch as many details as you can, but eventually, something will slip through a hole.
@SianaGearz yeah, agreed. That's really not an adequate scale for weighing anything at that low of a level, anyway - it doesn't even have adequate readability for the task, let alone actual resolution. Those things are for jewelery and weed, not single doses of substances which are notated in mg.
@toseltreps1101 facts.. dosing should always be thought out. And not only that but I first timer should always use a much smaller, tester dose. The difference between a smart drug user and a chemist.
Now that this blew up, you have a channel that only synthesizes obscure caffeine analogues while using yourself as the test dummy. Congrats!
He should probably get some rats to test this stuff on.
@@jttech44Like a real lab chemist would do.
Anyone else get the ad where a person on a stretcher falls over and it cuts walrus rolling over talking about a game testing job?
You put your citrus halves into your citrus juicer backwards.
These juicers are designed to turn the fruit inside out. So, you need to put the flat cut side facing the cupped part of thr juicer. It's counterintuitive, but it's a lot more efficient and a lot less messy that way.
oh good someone mentioned this lol
Residual effects from the last research chemical.
Devices meant to squish things are in the shape you want it to end in, not start in.
Or, maybe more helpfully, put it in juice side down. Idk why people expect it to work when the rind is blocking the holes.
The fitness industry is gon eat this tf up
As a big fan of both theacrine and methylliberine, this is very cool. I've always been interested in caffeine analogs.
if you don't mind my asking, how do those compare/contrast to just caffeine itself? also, recommendation on taking them together (with and without caffeine)?
@@frikghorganthere's little difference between them. Most of it is marketing hype so you buy the unregulated Supplement Industry's next super-new super-cool thing for more 💰
You'll get less jitteriness and a little lower blood pressure/heart rate. Longer lasting effects but at weaker strength per milligram.
Adding L-theanine is probably just as good.
But the FDA banned selling pure caffeine powder a bit ago (caffeine citrate😭), so maybe there's a loophole there to exploit.
@@frikghorgan Usually, synergy alongside caffeine. Gives it a bump without the negatives that come along with just increasing caffeine dosage. Theacrine lasts longer but is mild, dynamine is stronger but has a shorter duration. They're both interesting in their own right.
@@frikghorgan highly recommended n**tropics depot if you're interested
@@mamaharumi thank you, friend
I would patent this if I were you! You have a stronger and possibly safer version of caffeine with a marketable name. Could be a real money maker!
10:55 Oh come on, we all know how saccharine was discovered. We should get back to randomly licking things in the lab, we made such amazing discoveries back then and nothing you're handling and nothing it produced is going to be worse for you than ethylene glycol.
Another point, is that while in war times too we usually get thoses test data...
@@petitkus4408 I mean there are wars going on so
@@petitkus4408 war experiments were mostly horribly unscientific, barely any good information came out of experiment 731 or the yologhost other than how much of X does it take to end someone
Another example of licking things in the lab (accidentally) that led to a serendipitous scientific discovery happened on April 19, 1943, in Basel, Switzerland. It continues to be celebrated every April 19th around the world, affectionately known as "Bicycle Day". 🚲😃
A lot of the people you're so adamantly warning about the dangers of ingesting homemade chemicals with unknown safety profiles were kids taking a WILD variety of RCs back in the aughts and 2010s 😜
the whole RC mania continues til now actually.
im not in the game anymore, when i quit 2 years ago there was still dozens of compounds easily accessible
@@shiva_hardly_sarcastic huh...figured everything had moved off the clear web now? Already when I got out about ~8 years ago that's the way it was headed
@@dancoroian1 in germany where i am located its all still on the clear web
@@shiva_hardly_sarcastic well lucky you! Lol no such luck in the US
@@dancoroian1 eh, wouldn't call it luck necessarily since it did fuel my addiction quite a bit
Being a massive caffeine head myself, I'd love to have this in my life... Strong caffeine w/out the massive heart taking a battering!
I love how you were so meticulous in your scientific procedure for the synthesis, however when it came to "cooking" you were like - nope not taking the time to do this, let's rush through it. Gives an interesting perspective.
We need a doctor Nick “20.0 means 200?! What a country!”
More like 0.20g means 200mg not 20mg.
This could've been a curious ChubbyEmu episode.
A chemist makes his own energy drink, this is what happened to his nervous system.
@@a.c.2659 Chemist presents 👆 to the emergency room WIDE AWAKE...
Does anyone else find it hilarious when guys like LabCoatz or Nilered are doing a cooking segment and can't help but still phrase everything as though they're doing a hectic experiment 😂😂😂
It’s amazing how much of CZcams home chemistry is quick and dirty and still turns out good. I love this field so much.
18:00 As someone who has consumed various different doses of "substances". Higher doses of things tend to take longer to peak, I beleive this is simply due to your body's ability to process the material.
For example, when consumed THC is processed in the liver, it breaks down into 11-OH-THC which is actually what makes you feel high. Your body can only process so much THC a minute/hour, so if you consume a TON it simply takes longer to peak and lasts longer. It's the same story with Psilocybin and likley the same situation with your caffeine analog.
goated information. keep up with the good work
That's just wrong
For some substances, you will feel the effects much faster
@@RyeCAyeah “some”
@@RyeCA If it's going to pass through the mucosa or the stomach lining directly into the bloodstream (alcohol, cocaine, etc), you won't be waiting on liver metabolism to deliver actives to your brain. But if it's needing to pass through the liver first (edible THC, psilocybin, etc), you will be limited by the rate the liver can process at, and so you will see a delayed "peak" and a longer overall duration.
@@theKashConnoisseur Why delayed peak? As you said it is limited by the rate liver process it. It is continuous process, so liver does not absorb all in and release only after everything is processed.
There are some molecules that dont perfectly fit into their receptor but bend them in such a way that they cannot easily leave the receptor. LSD is only a partial agonist of the serotonin receptor, but its effects last 12 hrs. This isnt due to its solubility. Its the way it fits into the receptor. DMT is much closer to a full agonist, but doesnt last as long.
12 hours my ass. 6-8 if lucky.
@@scthomas1982 12 hours of you consider afterglow
@@scthomas1982 6-8 hours of perceived effects, maybe, but that doesn't mean that there isn't still binding at the receptor for longer.
Not LSD if it's only 6hrs for you. Or tolerance@@scthomas1982
LSD doesn’t even get its psychedelic effects from the serotonin receptor, its from the dopaminergic D2 receptor. And LSD has high affinity for serotonin receptors. What youre speaking to is called affinity, its not because they can’t leave the receptor due to shape, the molecules form bonds with the receptor, but just because a molecule fits doesn’t mean it’ll have a physiological effect. The molecule has to have a specific chemistry that allows it to interact with the protein in a way that it results in a physiological response. Your theory would be plausible, if these molecules weren’t non-selective agonists. They bind to at least 10 different receptor families, not just individual receptors, but whole family’s from SERTs, DATs, and so many others. And the affinities for all of these receptors differ.
Hi there! Great content. I find the chemistry of food fascinating, though I'm a coffee aficionado, so I'll stick to that 😅.
I gotta say, it is not advised to take any homemade chemicals... But it is darn entertaining to watch someone do it!
homemade alternative stimulants are fine, but I draw the line at red 40. Thank you for leaving it out.
I appreciate the effort put into these subtitles! They really do reflect the audio experience, whereas some other CZcamsr's subtitles don't seem to have as much care put into them. Thank you!
r u def?
@@nrbeast6000can you spell?
Bro....I want this. I think its time you market this stuff. I see great value and know that you're in the land of the sensible!
Hey this was cool man, but please I don't want to see a video in the future of you regretting doing more of this stuff. Seriously, you are very intelligent, you know the risk.
As soon as I saw how much was on that paper, I knew it couldn't be only 20mg...
I guess he's used to using imperial units.
How a chemist who measures things for a living misses this is baffling.
@@GarrettBlackmonthat model of scale measures tens of milligrams, it's actually a very easy mistake to make.
Yea. Now that you mention it.
Your non-improved results do not surprise me. Even with caffeine, its main effect is on the human perception of tiredness and focus. It's actual ability to improve performance is quite small and shows mixed results on an individual level, depending on the task. So it may help you get through your day or let you do more stuff since you feel more focused, but it's not going to make you superhuman. Unsurprising that dmax works the same way.
I've taken 1.6g of caffeine before (over a couple hours) and I can relate to some of your symptoms. I had lethargy, shakiness, anxiety, some feelings of focus (largely overwhelmed by feeling like shit), but also my heart felt like it was strained to the maximum and I was experiencing palpitations. I still felt like shit 8-10 hours later and my heart still felt strained, but if I recall correctly I actually fell asleep pretty quickly because of how exhausted I was. I don't know how at risk I was of actual health issues but it was generally a pretty good wakeup call to not fuck around and find out. Glad you're okay.
Great video, very courageous to take the stuff
The minute or so where you were going in wondering if you were ok and normal, analyzing the effects and if it was working….thats when I knew it was working 😂
Well, that made me giggle. Reminded me of the time I drank fifty shots of espresso on a dare. I tuned into a hummingbird (a 6'4 220lb hummingbird) and hallucinated a bit. Also think I peed out like half the water in my body. Made the Type-O Negative concert I was at a truly interesting experience.
Also, don't drink fifty shots of espresso. Seriously. I'm glad I threw up at one point, probably would have had a heart attack if I hadn't.
Fifty shots of espresso contains 3000-4000 mg of caffeine. That’s enough to kill a smaller person.
ehhh the average amount of caffeine in an espresso is 64mg so had you not thrown up, you would've had a stronger reaction than what this guy experienced but still well under the the lethal dosage which is 10g so you'd PROBABLY be fine.
Time didn't slow down for you on the 50th cup?
czcams.com/video/Cqd-_fHdTyA/video.htmlsi=PXo0JOPn9B8LMVA9
@@TurtleMountain the maximum safe dose is 2g. That was over 3g so yeah good thing he threw up.
Wow. I’ve had 8 in about an hour and it was pretty undesirable especially having heart conditions and being pretty sensitive to stimulants. 50 shots is somewhere in the 3.5 gram range of caffeine.
Thank you for sharing this especially the mistake and effects. Mad respect. Glad youre alright.
absolutely love the explosion's and fire reference
I am so glad you are ok.
So 150mg is the sweet spot. Got you.
😂😂😂
10:55 good lord, that Tom & Jerry cut-away unlocked some core childhood memories
i was typing a comment to ask when you'll make a tutorial on how to cook crystal and the video was playing then i heard "cooking met-" perfect timing x_x
I replicated your work and am having the time of my life, thanks bro
Good job! And you are correct there are no illegal caffeine analogues.
Truly, you are wonderful. Thank you very, very much for your effort and wonderful work
I think the misweighing incident is the universe giving you a sign to get a better scale 😂
"...buuuut whatever"
Thank you, I really appreciated that
Added my, "mélange of spices."🤣😆
I was seriously debating flashing a Dune meme there...not sure why I had to pick that exact phrasing, but melange does mean "mixture", haha
If you had waited longer you could have made a spice syrup that would actually flow! (Looking up that oleo-saccharide thing to experiment with lol)
I am by absolutely no means a chemist, but I just absolutely love chemtubers 😂 started with nilered, with bro playing whilst I fall asleep, then explosions and fire, then other science CZcamsrs, and found your channel, and I'm just so happy that I've found content like this instead of internet brain rot 😂 your content is just so flipping good!
you should check out the video by fraser builds on alchemy, it lends a perspective to chem that makes all of the other ones a lot more fun
Check out @chemdelic
Just what I needed to take my crippling caffeine addiction to the next level!
It made me chuckle so much that you misread something so pivotal. I could see myself doing the same thing.
0:26 Extracted it once? Nah, I extracted it multiple times daily!
On a side note, it is extra dangerous to drink chemicals despite the fact you might have read the MSDS and calculated the proper dosage for DMAX, as the product is so impure and unverified that there might be a substantial amount of deadly side products present in it.
Then, I shouldn’t be alive. I’ve been consuming said chemicals for 35 years. I’m not worried about it.
Today I drink yummy yummy poison cancer/caffine
Mmmmmm.....blegh ☠️
“Hey I made this 5 hour energy alternative! I call it 3 day energy.”
“What’s in it?”
“Medical grade methamphetamine.”
Desoxyn
Thanks dude this is so valuable to humanity.
Lol idk about that, but it was entertaining…
Happy to hear that you're doing fine
Lab made his own home-made Jet
xD good lord dude you're the best
Thank you for your service. This is what my kinda hero looks like.
As soon as I saw you measuring the sketchy compound, I immediately thought that it looks way more than 20 mg. I know because I am used to measuring roughly 1/3 of a 60 mg of atomoxetine, my ADHD medication (it's expensive, I'm poor, and the pill price doesn't depend on dosage), which is 20 mg. And basically 20 mg of anything is not much anyway, so it looked very suspicious.
Not being able to pay for medicine is just sad..that this is even a thing :(
@@meloney Yes. However, I am able to pay, it's just I have to be creative about it.
@@meloney I mean, I need about 30 mg for best results, but at that dosage previously barely noticeable nausea starts being uncomfortable. And since 20 mg pills and 60 mg pills cost the same amount, why pay for the former? Of course, it would be much better to just buy 20 mg pills for a reasonable price. Monthly supply would cost roughly 10% of my income if I were buying them as is. What can you do? Capitalism works in mysterious ways.
Felt that on the price of atomoxetine... is your doc at least getting you the manufacturer's discount?
@bytefu but that isn't solely a capitalist thing. I am from germany and get ADHD medication as well. In my case Elvanse/Vyvanse or whatever it is called elsewhere. Its lisdexamphetamine, 30mg for me. I pay about 5 euros per pack of 30. I could get the max dosage of 70mg for the same price. But painstakingly measuring half of each cap for about 2.5 euros (around 2.75 usd) saving really isn't worth it for that...
Noone should pay 10% of their income when they need medication. I know how important ADHD medication can be. Lisdexamfetamine for the first time allowed me to go outside in public and just be myself without overthinking everything which causes me to panic.
That would even be worth 20 euros for me per month. But rn per year its about 60-65. I could get even that completly without the 5 euro cost too, if i did the paperwork at the social healthcare insurance. (which isnt a lot at all, i did that for many years and got all meds without the 5 euro minimum self pay)
In the US however, this isn't capitalism, this is terrible greed and really sad. Capitalism can work in other ways, such as it does with meds here. The meds still are getting paid for of course. Just not by the one who needs it. I hope that one day things change and you wont have to pay for them that much anymore!
You took one for the team and OD'd for science 🚀 good on ya m8
Honestly this is what every student taking physical chemistry feels like after doing 10000 calculations to solve a problem, only to realise the end result is wrong because they didn't change the units in some part of the process, in spite of the procedure being ok. I feel you 😭😭😭
LMMFAO YOOOO That Beavis and Butthead clip insert tho! That was hillarious!
I wanted to do more, but worried it'd be too weird to too many people, lol
@@LabCoatz_Science Embrace the memes
"Don't do it at home" then proceeds a step by step tutorial with the exact doeses and where to buy/get them from
It’s amazing that technically you’re an incredible chemist/story teller, but when it comes to using a lemon squeezer you use it the wrong way👀 epic video, glad the algorithm took me here!
Subscribed. Excellent video :)
I really dig how you talked like NileRed for a minute when shouting him out that was hilarious 😂😆😂😆
I hope you get a patent for DMAX and get rich. :)
I once isolated some caffeine from tea and ended up with a few crystallised needles of a white substance on a glass plate. Not seeing that as being dangerous, I licked them off. Big mistake! I ended up on the couch for four hours, shaking, sweating, with a racing heart and the fear of collapsing. Not a pleasant experience and a potent reminder to exercise caution when doing stuff like that.
When I was a kid I found my step-dads pre workout stacker 3 caffeine pills. I took 3 thinking I'd get some energy. Ensue 6 hours of me feeling sicker than I ever have in my life. Learned not to mess with caffeine that day.
Lol that must've been scary. I had a similar experience but with 2c-e. I thought I was doing a small bump of amphetamines just to stay a little awake but it ended up being an 18 hour long psychedelic hell.
Can you even imagine coming back to see how LabCoatz is doing to find he hasn’t uploaded in years and then find out he accidentally off’d himself by taking 2grams of fucking caffeine to the face?! I’m just…you are so lucky dawg I am so glad you’re alive.
Loved the extractions/fire plug. Find both channels people he is great. He would not be thrilled with this yellow result
Cool stuff! Nice work man