Thinking Big: Bruce Beutler, MD

As an internationally recognized leader in immunology, Dr. Bruce Beutler's original studies at UT Southwestern led to the identification of tumor necrosis factor (TNF) as a key mediation of inflammation and to the identification of Toll-like receptors as sensors that act like sentinels to alert the host immune system when infection is present.

[@CarolineWirthle]

Any opinions on depression, and misregulation of hormones, misinterpretetation by receptors in the context of autoimmunity?