Malaria diagnosis: Addressing the issue of HRP2 gene deletions (UPDATED VERSION)

Access to an accurate and timely diagnosis is critical to preventing a malaria infection from progressing to severe illness and death. WHO recommends prompt malaria diagnosis either through microscopy or rapid diagnostic tests (RDTs) for all patients with suspected malaria. The hundreds of millions of RDTs sold each year are designed to detect a specific protein in a person’s blood. Parasites that have mutated to no longer express that protein can evade detection by RDTs. Such mutated parasites have now been reported in more than 35 countries - mainly in Africa and South America - and they are complicating malaria diagnosis and treatment. This video describes the problem of Histidine Rich Protein 2 (HRP2) gene deletions and what can be done to address it.
More information: www.who.int/te...

[@publichealth1061]

Thanks

[@MrLalramchhana]

Why dont we just provide foldoscopy to health care workers who cant afford microscope 😀

[@neangsotheasothy9184]

So, HRP2 is a gene or a protein? I have heard sometimes gene but sometimes protein? Please kindly clarify. Thanks.

[@janecunningham8640]

Genes are the blue-prints for proteins. pfhrp2 is the gene which expresses the protein called HRP2. Parasites lacking the pfhrp2 gene cannot produce the HRP2 . If there is no HRP2 in the blood then the RDT will return a negative result

[@DjibySOW]

If you write it in MAJUSCULE like HRP2 you are Talking about the protein than the hrp2 gene product. In the RDT we are talking about the antigen (HRP2 pRotein)

[@user-iy8lb2io4i]

Наложить мораторий на принятие пандемического соглашения!

[@gracie99999]

idk mang..so many problems