The surprising truth about histamine intolerance | Dr. Will Bulsiewicz
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- čas přidán 4. 06. 2024
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We've probably all heard of “antihistamines,” medications that can ease symptoms of hay fever and other allergies.
But what is “histamine”? It’s a vital chemical that our bodies produce, and it plays a role in a number of functions that support our health.
Histamine intolerance seems to be increasingly common, but it’s difficult to diagnose. Some people may not be aware that they have it or how to treat it.
In today’s episode of ZOE Science & Nutrition, Jonathan speaks with Dr. Will Bulsiewicz, ZOE’s U.S. medical director, to learn more about this flourishing area of research - and the best ways to identify and treat histamine intolerance.
Will is a board-certified gastroenterologist, and New York Times bestselling author of the microbiome book Fiber Fueled.
If you want to uncover the right foods for your body, head to zoe.com/podcast, and get 10% off your personalized nutrition program.
Follow ZOE on Instagram: / zoe
Mentioned in today’s episode:
Resistant potato starch supplementation reduces serum histamine levels in healthy adults with links to attenuated intestinal permeability, published in Journal of Functional Foods
Link: www.sciencedirect.com/science...
Histamine and histamine intolerance, published in The American Journal of Clinical Nutrition
Link: www.sciencedirect.com/science...
Histamine Intolerance: The Current State of the Art, published in Biomolecules
Link: www.ncbi.nlm.nih.gov/pmc/arti...
Books:
- Fibre Fuelled by Dr Will Bulsiewicz: amzn.to/4bzmUXP
- Every Body Should Know This by Dr Federica Amati: amzn.to/4blJsLg
- Food For Life by Prof. Tim Spector: amzn.to/4amZinu
Episode transcripts are available here: joinzoe.com/learn/category/po... - Věda a technologie
Since histamine intolerance touches about 3% of the population as you said, maybe a long video on its subject could be a good thing? Diving in in more details, medications potentially causing it, other conditions linked to it, dealing with it on a day to day basis, histamine friendly menus, dos and don’ts, how to heal the gut when one is intolerant to histamine, what to do when intolerance doesn’t go despite a good approach to diet, are there genetic predispositions etc…
Hoping you’ll take on my suggestions. Thank you for all your podcasts anyway.
Maybe he should write a book?
Maybe any information at all about how to treat it. I wasted a 1/2 hour listening to this to find out nothing that couldn't be communicated in 2 minutes and I found out nothing at all about treatments. I'll be their video on inflammation is more of the same.
I think the 3% is underestimated. I have hives and psoriasis . I grew up eating foods I am now highly allergic to. Turns out symptoms can often take up to 72 hours to kick in so it’s impossible to gauge sensitivity. I had testing done but not till after 10 years of trying to figure things out on my own. I’m thinking lots more people today are becoming more and more allergic. I had no issues until my late 20s . Now 50. Then there is the ones that have symptoms but doctors can’t find the cause so they label it with something mean wile food is often the culprit.
@@sabrinashaw9939He has a great book and Cookbook! ☺️
Fiber Fueled and the Fiber Fueled Cookbook.
He goes into a lot more detail about different intolerances, with lots of recipes for each type of intolerance and how to heal your gut so you can safely work those foods back in. 🤗
They are excellent resources for healing gut issues. 👍
Right.. I agree. But as mentioned in this video i think Leaky gut / Inflammation can definitely be a huge factor as to why people are experiencing allergic reactions years later.
My symptoms are below: anyone else?
Hives
Nasal congestion, excessive mucus
Heart palpitations
Asthma
Hives triggered by heat (sun or food)
Contact hives when I touch cold things
hives with no apparent triggers
Get extremely stuffy by alcohol
Always have to be on antihistamines
Animals?
Your symptoms are very similar to mine.
My histamine intolerance was triggered by binge drinking alcohol on an empty stomach and eating extremely spicy food. It must have inflammed my gut, impairing DAO production.
I've had two bouts of histamine intolerance, the first time it lasted for a year, the second time only for a couple of months. Both times it was caused by prolonged stress. Both times it didn't come about when the stress was the most intense, but when it was already subsiding. I took antihistamines, loratadine seems to have the least side effects for me. Antihistamines only took the edge of it, so I was able to sleep, but didn't take the itch or swelling completely away. For some time I had to double the dose. I was on a low histamine diet, until the symptoms subsided and then I slowly introduced more foods. The low histamine diet is extremely bland and sad, and I think it's missing too many nutrients, so it cannot be a permanent solution. But most importantly, I've been trying to manage stress better, I take care of myself emotionally. I hope you recover very soon 🤗
This video is life-changing for me. It confirms what I always suspected to be true - I am extra sensitive to histamine. I just couldn't figure out why. I am a urologist (yay for histamine and erections!) but couldn't find any good confirmatory tests. I was told to cut out tomates, chocolate to help with my acid reflux - and it made a world of a difference. However, I had formal GERD testing done with a BRAVO capsule - and I didn't have nearly enough reflux episodes to qualify for GERD. I now suspect my improvement in cutting out tomates and chocolate aren't due to the acid reflux itself, but the histamine load. My father and I are also "allergic" to eggplant (and he doesn't like tomatoes). Everyone always so surprised when I list that an allergy. And my reaction is worse with alcohol which makes sense now. Also benadryl works wonders for my "hangover" when I drink - also confirming my suspicions that my "hangover" is just from the histamine. Now I can't wait to add pea sprouts to my diet and see if this allows to work back in my tomatoes and wine!!!
I feel exactly the same! I have a crazy reaction to alcohol: sneezing, runny nose, awful sinuses. I often take Benadryl before a night out! I also have had terrible GERD and digestive issues, including gallstones. I am so reluctant to cut out tomatoes - they are a almost a daily ingredient in our cooking! I agree with you - I'm going to check out the sprouting peas.
I found your comment very interesting. I find that alcohol depletes Electrolytes have you tried replenishing Electrolytes to see if that stops the Histamine attack?
More histamine content please !
I am very grateful that there are doctors who know about histamine intolerance. Having said that: healing leaky gut when you have histamine intolerance is like driving out the devil with the Belzebu. Histamine intolerance cause itself leaky gut and can only be cured when the intolerance goes away. Those affected know this only too well. You go around in circles. What was not discussed was a possible dysbiosis, which in turn can lead to increased release of histamines in the intestine, as there are many good intestinal bacteria that produce histamines themselves. For dysbiosis fermented food could help, but you can not tolerate with HI, so you go in circles again.
Exactly.
L. Glutamine can help with healing a leaking gut. I struggled with a leaky gut and had L. Glutamine, with vitamin C and Zinc and this helped me. I know people with histamine intolerances have to be careful with some probiotics, especially if they come from fermented foods, but I am not sure if they would react badly to L. Glutamine, zinc and vitamin C. It might be a good place to start and then slowly introduce probiotics.
@@cherylhmackie Thank you. Yes, Glutamin can be helpful. I did not tolerate it at all unfortunately. But yes, for some it is helpful.
@@Anita-wh4vr oh that is a shame, I am really sorry to hear that. Very complicated. I hope you find something that brings healing.
@@cherylhmackie Thank you 🌺
1. Heal gut lining-no gluten or grain
2. Add HCI if needed to reduce pathogens coming in
3. Supplement w/DAO &glutathione to keep the cycle going.
4. Elimination diet to see what you can tolerate at this time.
I went strict carnivore-BBBE
Beef
Butter
Bacon
Eggs
For about 18 months. I was so sick that it took awhile to figure out the histamine sensitivity.
The advantage of pork kidney as a source of DAO, as compared to sprouted legumes, is that pork kidney does not contain saponins, which increase gut permeability, whereas sprouted legumes do.
The advantages of plant-based sources is that they are safe for muslims, jews, hindus, vegetarians, vegans and anyone with a meat intolerance, they’re better for the environment, they’re cheaper. Oh, and no piggies have to suffer and be killed.
Legumes cause me so much inflammation…
Also does not contain oxalates or salicylates which can cause issues for those with HI
Legumes contain lectins if they are not cooked out thoroughly.
Interesting. Thanks for sharing!
This was an easy guide for people to understand HI, which can be hard to explain (both to lay folks and medical professionals). I found it farly accurate, and I'm glad you mentioned "what if HI is the root cause of all your ailments?"
Been suggesting this to my PPC, cardiologist, neurologist, allergist, gastroenterologist, gynecologist..., but they're not really listening, and I'm being treated as a collection of body parts 🤔
Why do you stay with them to be their punching bag? Find a good Nutritionist that will listen to you. You pay them for service, now get the good service.
Sadly the nutritionists I have been in touch with have had zero knowledge of HI; one even questioned its existence
@@Sunny-qi4ti Brush your hands together in front of them and than walk out. They work for you, you don't work for them if they didn't give you service don't pay.
@@Sunny-qi4tiwow. That's surprising...
That is exactky what I was living😢
I'd actually like much more 'nerding out' please. I really appreciate your content and would like much more detailed analysis. The Zoe crowd aren't here for primary school explanations. We want the whole thing because many of us are suffering in some way and just want to get better. I'd like to know for instance how to reduce IL1b, IL6, IL17a and TNF Alpha. I'd like to have known also how estrogen contributes to histamine intolerance but that wasn't even touched on which is a shame as it effects many women during the menopause. I'd like to know also why we are producing extra histamine and there was no discussion about gut bacteria contributing to this problem and how LPS-producing bacteria may well be likely responsible for much of our symptoms. PLEASE share more, not less. Thank you.
Same. I don’t know why ppl on Podcasts are so apologetic about their academic knowledge. I see it in different ppl, not just Dr B
More info on how to address it would have been good. Talk to Dr Louise Newson about how it ties into menopause? How does one source legume sprouts?! What of antihistamines?? It was great to see this being addressed but it was too short and left more questions than answers.
Yea seems they only speak on the problems and not the diet/supplements solution
Great podcast, as usual full of useful information (nerdy or not) i would like to hear a longer podcast with a deeper dive into foods for and against. Many thanks Zoe
Thank you very much for this wonderful video and podcast
Would be interesting to have a video on Mast Cell Activation Syndrome. This is what I have and the information on it is close to nothing.
Daily antihistamine plus another medicine from my Gastro have been life changing for me!
how did you get diagnose?
@@marym3355 process of elimination. It was only named in 2007, so very little is known about it. And there are no tests for it. So the Gastro tested me for literally everything else it could be (expensive process) and all those tests were negative. Since being on medication, my symptoms are mostly gone except for an occasional flare up.
Hi. Do you know if your basophils and eosinophils are elevated with your mast cell activation syndrome?
What medicine you used for your gastro?
Also how have it been life changing to you?
Can you be more specific about HOW WE HEAL from histamine intolerance? Because I have been on a low histamine diet for YEARS and sometimes I also have to take DAO supplements [when there is too much polen] + antihistamines.
I want to heal my gut, but have no idea what to do since fermented foods don't really help.
ps: you don't have ZOE where I live, i would love to be able to get to know more about my microbiom.
so please in your next podcasts, make sure to offer some actionable takeaways not just talk, which is nice, but I would love to be able to know what to do to fix.
Thanks
This diet that I’ve linked is what healed mine. I have to take DAO supplements daily along with Quercetin and Vitamin C. I’m also healing my microbiome with kimchi and I notice the difference now when I don’t eat it. I’m now able to tolerate more foods.
www.mastzellaktivierung.info/downloads/foodlist/21_FoodList_EN_alphabetic_withCateg.pdf
I am doing a low-histamine diet for more than 3 years now and I thought my gut will heal itself when I give it a rest but nothing has changed. In fact it even got worse. I am now eating gut healthy diet with moderate amounts of histamine like yogurt, green banana and even some fodmaps like garlic etc. I learned that a low-histamine diet is NOT the treatment but only improves the symptoms temporarily. I wished I knew this earlier. I am not healed as its only been 3 weeks but I can feel its improving. I also take probiotics. I have read it can take up to 1 year to heal your gut and at least 1 month of probiotics to see improvements in your symptoms. So give it some time don't overdo it include foods in your diet step by step, that's what I'm doing.
thank you for sharing your experience, i really appreciate it! I started added maybe 3 weeks ago fermented cereals [like a type of sourdough starter] and I take a little little bit with each meal and noticed HUGE improvement and I noticed that i can eat sour kraut so I add that every week, I can eat cheddar ...and lately I added a bit of peas. I want to slowly add more veggies [no onion garlic yet :)) i am not that courageous]. Unfortunately sugar and fructose affect me big time [emotionally] so I cannot have any fruit yet...but hopefully soon my gut will heal, having bacteria to properly digest fructose and be able to have fruits soon. @@tahirballikaya213
I take DAO and various inositols before I plan to eat a triggering food. HI also gets worse during peri-/ menopause because of estrogen loss.
Carnivore diet helps a lot to heal your gut
@ZOE, can you create a podcast looking deeper at the correlation of histamine intolerance and acne, please?
I've been with ZOE since August 2023. Recently, I got my microbiome retest done, and my results improved massively, YAY! I feel better. Bloating and lethargy is a thing of the past, and my good/bad gut bacteria numbers improved also.
However, during the same time, I've been working with a specialist to cure my acne.
I've changed and improved upon so many aspects of my life, including the holistic approach, but my hormonal acne keeps coming back. More recently, I'm getting hot flushes. I'm 34 yo, and my TSH, T3, T4 are normal. FYI, when I had a benign thyroid tumour at the age of 14yo, my thyroid tests were exemplary, too.
Recently, I got a histamine intolerance test done, which shows that my DAO level is at 3.80 (supposed to be above 10)
I'd love it if you could dive deeper into this topic, as I'm sure many would benefit from this information!
Many thanks 😊
Where did you have this testing done please?…🙏
Excellent. Thank you for sharing.
Post covid, I had enormous lips and tongue, so swollen and painful that couldn’t function. Nothing helped until I took a probiotic with histamine control. Immediately, I could tell the difference and the minute I stopped taking it, my lips would swell again. It I took about a month of taking the probiotic for my mouth and lips get back to normal.
That's amazing. out of interest what proabotic did you take ? I'm struggling with histamine levels and not getting much medical support
Hi you have to be careful of what probiotic. There are 2 good bacteria that is high in histamine. Which are lactobacillus casel and lactobacillus bulgaricus. These are found mostly in fermented foods.
I was diagnosed chronic sinus infections years ago. Then a nurse happened to recommend eliminating dairy to see if that helps. It did. It was life changing. I get sinus infections with all dairy and soy. Very sad.
Dairy is mucus producing . Causes nasal drip that irritates the throat . Mucus fills the sinus and blocks them . Sinuses should be empty and full of air only . The ears , the nose and throat all affected. The mucus goes into the gut and an cause loose stools . Headaches and cough ,sneezing and even eyesight affected . The blocked sinuses swell and push the eyes forward altering vision . Pain occurs .
Thank you!
I've been followed for 4 years on different things and never this whole approach. I cannot wait to make the test. I know I have it though, cause of all the symptoms he talked about I have all of them 😢. Would love a second part to this to know how to heal my gut and reduce the symptoms so I can, one day, enjoy the foods that I love!!
Thank you so much for the great advice Dr. Will. You mentioned sprouted legumes being good foods to increase DAO. Are these sprouts to be eaten raw or can they be cooked ? Thanks for the advice.Joyce
Thank you so much. Think that is what my daughters health issues are due to. I am very appreciative.
I know from experience that excess histamine triggers my chronic sinusitis; for example, in the form of aged, fermented foods. Cheese, sauerkraut...however, tomatoes and avocados are perfectly fine. But, even worse is...sugar.
Thank you that perfectly explained my body's reaction to two fish dishes I've eaten over the years. One put me into A&E 38 years ago and when I had recovered quickly (your half a day timing) they put it down to an allergic reaction to shellfish.
I also love tomatoes and consume a large amounts of home grown ones in the summer coinciding with hay fever! I might reduce my tomato consumption this summer.
I enjoy the style of presentation including the "nerd outs" ! Yes health is a serious topic but the presentation is relaxed, fun and entertaining. Better than just giving us boring facts and words we cannot pronounce. I enjoy the Zoe presentations. They are one of the few health videos I watch all the way through. Thank you Zoe team! ❤
Dr B, as usual, doing God's work. Because of conversations like this i have discovered my worsening HI and decades of suffering and am slowly starting to get my strength back.
Hi and thank you very much for your video. It took me about 5 miserable years to work out by myself that I suffer from HI. Drs were useless and blamed all my symptoms on my type 1 diabetes. It would be priceless if your team's compound scientific knowledge and ZOE influence could try and bridge the gap in the acceptance of HI as a real medical problem by the conventional medicine and NHS. Maybe working, connecting with NHS dieticians would be a good start. We need a change.
Hi
May I ask what symptoms you have?
My symptoms are skin rashes, cough and sweating. I don't have any digestive symptoms.
My problem started when I binge drinked alcohol on an empty stomach and later ate extremely spicy food. I initially had gastric burning pain and diarrhea, which all subsided in a few days.
@@jacoblas1371 Hi my symptoms were face flushing after some food and blocked nose, night sweats and burning sensation in my intestine . Day dizzy sensations and tingling, bloating and low mood.
@@user-ge8kf3bg5h
I am trying to heal my gut taking Glutamine and drinking cabbage juice daily.
I’ve really suffered for 30 odd years and all doctors would do is prescribe antihistamines. It’s really debilitating so good to finally discover this. How do you sprout peas, etc. ?
This has been a life long journey for me multiple autoimmune conditions from asthma to MCAS. The DAO information is fantastic.
The DAO information is awesome.
Gosh that was so interesting. My vegetarian daughter has had dermatitis since she had a 7 day course of penicillin for tonsillitis ….
I wonder if these antibiotics have affected her DAO production? And of course she eats all the histamine rich foods being a veggie.
Looks like she needs to fill her plate with sprouting legumes.
Thanks-that could make sense of her rather strange situation!
Thank you for this broadcast. I had some food sensitivities/allergies. I found Quercetin helped.
KL🇦🇺
I take quercetin daily, and twice daily in allergy season. Really helps
Thanks for your reply that Quercetin has been a help for you. KL 🇦🇺
Love the information but not the far-too often interruptions.
Could not agree more. Such poor editing.
I started following the nourishing traditions diet about two months ago. Then I started eating for my menstrual cycle since I’ve always had incredibly painful periods with no diagnosis of anything being wrong. Increased my intake of many foods dramatically: fermented veggies, kefir, nuts, citrus foods, avocados, kombucha, and basically everything else that is histamine producing or high. I was also drinking apple cider vinegar before my meals if they were a little carb heavy to mitigate a spike in blood sugar. Needless to go on, I’ve been eating high amounts of all these foods for two months. A week ago I started feeling horrible. I had THE worst menstrual cramps in my life, headache, rash on my hands, horrible post nasal drip and nasal congestion, heart palpitations, and more. I’ve been investigating for 48 hours and I was completely unaware of histamines in food and definitely of histamine intolerance.
This is yet one more example that no one diet fits all people. I am so thankful to have all this knowledge and for all these resources!!!
So, what will you do differently?
I was so shocked at how high avocados are in histamine 😢
Dear researchers at Zoe, thank you for your episode on histamine intolerance.
I am affected by this and it took a long time to find out about it and to find a way of living with it.
It was thanks to the work at Zoe that I started my trial and error process in 2020 and now I can say I live happily. I discovered that by drinking the juice of a lemon every morning keeps under control my histamine levels. I also discovered that on good days I can eat little quantities of the food with high histamine. Overall now I can eat a lot more things. Today I learned again something new about how to control histamine. Thank you!
Hi Stefania,
Every morning, one lemon or lime? Does it really help?
Thanks,
@@farazk9729 Well it helps me. I know lemons/ limes have antihistamine properties, but I guess every body is different. We should know more about this. Best wishes. Stefania
@@stefania26563 thanks, you too.
Add pink salt too to the water
I’d love that, but migraines dictate no citrus
I self diagnose myself with with. It's the only thing that makes sense. I'm hoping when I see a specialist he can confirm what is wrong. Me having this has made me so knowledgeable about health as I have been researching for years.
Would be interesting to differentiate between histamine stimulating and high histamine foods
Very informative and helpful. I suspect i have histamine intolerance as i react badly to all high histamine foods.
Could you please do a talk on Oxalates, as they are an issue as well.
Thank you for doing these talks. They help make sense of food intolerances.
So, how do you go about healing the gut when fermented foods aggravate your symptoms? For those of us accessing public healthcare & unable to afford joining Zoe 😊.
Hi, this is a very interesting podcast. I have been diagnosed with severe eczema due to a histamine intolerance about five years ago. Since then, I have been on an extremely limited low histamine diet (chicken, rice, veggies and sweet potato, basically), because I really do react to other food! and it is NOT temporarily! Your podcast has given me some insights, but I really do not think that a low histamine diet is that temporarily for most people who suffer from histamine intolerance. Thank you!
People on the carnivore diet don’t eat any of those problematic foods and they are quite happy but yes, it is restrictive. I find seed oils are the worst thing for me for inflammation but I’m currently avoiding histamines and oxalates as an experiment - I’m sleeping so much better and finally loosing some stubborn post menopause weight. Thanks for a great interview !
Carnivore Style of life it’s amazing for histamine intolerance
I agree:) also GF and grain free!
Id also like to take this opportunity to thank both Tim Spector & his team for guiding us through the covid pandemic & who were always 1 step ahead of PHE.
Im just watching the drama "Breathtaking" on itvx & although its based on a book, the majority of it is based on truths
Thanks, but how do you consume sprouts, raw, coked?
If we cook it, does it lose the sprout properties?
I love this podcast and learn something from each episode. Thank you.
I have had histamine intolerance since I got Covid a year and half ago. Gasping for air and terrible stomach issues. Lost 25 lbs. I had to eat foods low in histamine. What seems to help start digestion again was taking sodium butyrate. It took a while and still not back to normal. Anyway thanks for the informative video!
I was an overweight bloated, spotty IBS sufferer all my life until I was 60 and have changed my life recently ....I now take over the counter antihistamine meds daily....one drowsy for night and a non drowsy for day and it's all fine now ....
Since doing intermittent fasting and eating whole foods ONLY ...it has changed my life ... I'm now 66 and lost over 50lb, feel like I'm 40 years old .... GREAT!!!
Processed foods is the king pin here and eating in a short time frame....one or two meals a day is enough ... with no snacks and plenty of fluids with a good mineral supplement...
It's easy and will change your life!!!!
Try it, it's a simple no brainer.....
Keith UK ...
What are you like with meat consumption?
And coffee? I feel IFasting is key and water to flush histamine levels
@@toddy5496 I just have regular proteins from different meats in my diet to provide the best protein profile around 75g a day ..
Coffee no issues...I take it with a drop of full cream in my fasting window ...most days I do OMAD and sometimes take 2 meals in about a 4 hour window..
I just stay well hydrated with plenty of electrolytes and not then ever hungry ...
Meals taste FANTASTIC on I.Fasting and whole foods have completely healed my gut lining. .We we're NEVER designed to eat this processed c*** Trouble is it took me 60 years to realise it ....and btw ...stay away from carbs and sugar big time!!! They simply spike the insulin production. .which is the simple fat storage hormone! ...low carb, whole foods NO weight gain ...end of !! and it Will work!
It's not rocket science but the idiot docs would have us believing it is!!
Good luck..... Keith
I have exactly the same experience
@@toddy5496, Red meat, salt and Water😅 I do coffee too…
Thanks so much for this very informative video! I am know convinced that my chronic migraines are at least partially caused by histamine intolerance. I will try the legumes!
Self diagnosed histamine intolerance a while ago.Subsequently diagnose with coeliac disease late in life. All manner of symptoms as Dr Bulsiewicz describes from migraines to lichen planus to eczema and stomach aches. Would love to know more about interaction between histamine intolerance and coeliac disease. I've taken the Zoe test and improving my microbiome does seem to have helped as has cutting out gluten but daren't risk an avocado yet!
Same!
Hi.
Did you have diarrhoea with Celiac disease?
Very interesting video. Interested in how this might relate to SIBO/methanogens and MCAS (Mast Cell Activation Syndrome), Did the ZOE thing for 4 months with a bad poop test and a known intolerance to fermented foods, so no cider vinegar, no kimchee, no sauerkraut - not a good fit for me. Keep up the good work.
Question for Dr. Will B: can Chronic Idiopathic Urticaria be classified as a form of histamine intolerance?
Also, what is the role of long-term antihistamines in the management of this group of conditions?
Please do tyramine intolerance! I have tyramine intolerance due to chronic disabiling migraine. Tyramine and histamine are similar so it was confusing to tease out which it was. I've been seeing neurologists for 15 years and none of them brought this up to me, but when I figured this out with my own research and brought it up myself to my stanford neurologists, and even stanford allergist they were well aware of the tyramine/migraine connection. I beleive this topic would be very helpful as chronic migraine is a common neurological disorder which is often triggered by tyramine.
Goodness, that explains my problems after eating.
At long last someone is talking about histamine intolerance. GPs and Gastroenterologists look at me as though I’m made. Taking DAO supplements that have little effect so have to keep on low histamine diet or else I suffer 48 hour migraine. Exercise also causes histamine build up😢
Would be interested to know your thoughts about the role of histamine in Post COVID-19 Syndrome
What kills is that although I’m keeping to a strict low histamine food, I still wake up in the middle of the night with terrible itching and scratch myself raw. Thanks for the valuable information .
Might be parasites? I’m high and dr said take HCI to kill pathogens coming into the body
I also meant to ask you Dr. Will, in the last 6 to 7 months I’ve developed a very itchy redness on my throat and a few red patches on the face. Could this be the cause of a histamine intolerance ?
Could you do a podcast on any up to date info there may be lichen planus of the limbs? There is so little info on the cause and so little apart from steroid creams to manage it
Great Discussion with Great interview questions from the Host and Knowledge from the guest speaker. Thank you so much!
Through self experimentation i have figured this out without the science, just by symtpoms. A low histamine diet def worked for me and a recent chat with a nutritionist i established that dao is a thing for me probabky. Can’t get it in NI as yet though. Doubt my dr would prescribe as they think im mad! Never a holistic approach by a dr and specialists. So this is all great to hear! Want more help and solutions. Keep it up! Great work!!
Yes, I supplement with DAO since my glutathione cycle genes showed mutations
Thanks, I have to take antihistamine daily and when I don’t my nose streams and I get skin break outs and headaches. It does not seem to be food related and I am confused about the worsening symptoms that my GP did not seem worried about, however I am avoiding going out in the fresh air .
Could some mold exposures somehow trigger a histamine intoxication? That is exactly how I react to a few molds.
Also mold left me very chemical sensitive and exposure of
Mold also can trigger those same symptoms.
Question on legumes if sprouted does that stop the effect they have on G6pd deficiency? Or do non legume seeds like broccoli also have high DAO. I am slowly adding fermented foods back in and have recently added mustard and broccoli sprouts.
yes, I react to mold as well
Would microgreens work as well as sprouting? I feel like you can just put seeds in soil or soilless media and harvest them after they've sprouted, whereas sprouts you have to rinse 2x-3x a day and check on to make sure there's no bacteria contamination, spoilage etc. ADHD does not play well with that kind of thing. The more error proof the better.
Good question. I'd also like to know that, so commenting here if anyone answers.
Would love to know the steps to improve leaky gut for those who have histamine intolerance or how to determine if it's a DAO gene issue vs. leaky gut. I've been on a low histamine diet for about 5 years now and it's the only way I've been able to manage my symptoms.
same here, I can manage my symptoms but not healing.
If you have genetic testing, you can find out if you are not making enough DAO.
@@cynthiathurman3108 till 30 years I never had histamine intolerance till I got Covid plus botox injections made things worse.
it has been 1 year post botox still highly sensitive to histamine, living on a limination diet. I will try sprouts,
GLUTEN probably created the leaky gut. Took me about 4 months GF to heal my gut.
Histamine Block and Histamine Digest by Dr Ben Lynch's company...Seeking Health. Good luck. I'm waiting to get Dr. B's products too.
Very useful. I damaged my body's ability to produce DAO through excessive use of ibuprofen. Then I got histamine headaches and took more ibuprofen ... a downward spiral!
How did you find out that ibuprofen had affected your DAO production? (btw… I’m stopping taking ibuprofen for my headaches from today, just in case! thank you).
Google which medications affect histamine. NSAIDS can increase histamine production.
I had a series of medical tests which identified the problem. Ibuprofen damages the body's ability to produce DAO, which manages histamine.@@sallyescrader1434
I am wondering, does this have anything to do with being allergic to animals dogs? Cats is it the same thing he said something about it at the beginning of the podcast all re-listen to it and see if that’s the same. Not sure please answer if you see this have a great day.
MACS affects many many people who have had been exposed to environments with toxic mould. I healed histamine intolerance by healing my gut barrier
Any advice? 🙏🏻
@@Kukkema go on a histamine diet in the short term to relieve symptoms. Then detox the mould using binders, and find a specialist in Frequency Specific microcurrent. (See Dr Neil Nathan’s book Toxic, and see Carolyn McMakin for FSM protocols). You will need to rebuild the integrity of the gut barrier using specific probiotics for this purpose, eating polyphenols like berries, flax seed etc. If you have SIBO and other infections as well these will also need treatment, and FODMAP diet can help alleviate symptoms in the short term. It will take time, but it’s possible to heal if you find the right functional medicine support. I did it in 3 years.
Are histamine intolerance tests (hair/nail clippings) reliable?
How do you heal the gut barrier? It’s not mentioned here, is it on another podcast?
I drink cabbage juice and take Glutamine daily to heal the gut.
Cabbage juice and Glutamine healed my gastritis in under 2 weeks. Still waiting to hear the leaky gut
What if you have oral allergy syndrome as well? Eating foods fresh causes hives in my mouth and a runny nose etc but eating cooked would be bad too? 😢
Will you talk about cytokines inflammation?
Yes specifically IL1b, IL6 and IL17 plus TNF Alpha - the four coachmen and horses - they turn so many many diseases, not least histamine intolerance, and for many cancers are always elevated. How do we use food to reduce them and where are there so few tests on the market to allow us to know which ones we are elevated in?
Any low histamine recipe books you can recommend?
This is the best one I’ve followed. www.mastzellaktivierung.info/downloads/foodlist/21_FoodList_EN_alphabetic_withCateg.pdf
After 30 years I finally realised why cows milk caused my skin problem (painful eruptions on face and upper back). It comes down to the cow genetics. A1 milk from 'modern' black and white cows. This has a histidine component. A2 - 'old fashioned' Guernsey, Jersey, dairy shorthorn - doesn't have it. My brother (same issue as me) now buys Guernsey milk from a local farm and he is fine. However, I believe there is an interaction with hormones. Both of us began to get the problem at puberty although from an early age I had an aversion to drinking cows milk. I seem to be OK now after 30 years of evading nearly every product containing cows milk (although later I realised cheese seemed to be ok, possibly because the casein is denatured). I used to take an enzyme tablet when dining out and this worked but these seem to be no longer available (Prolactyzme forte).
Never needed antihistamines until getting married & inheriting 3 cats this I kept in check with Loratadine but since Covid I have full intollerance , need a blocker
Me too. Been using a H2 Blocker for 24 years now for my chronic urticaria that I've had since I was a child. It's been a real problem throughout my life but the H2 blocker was a God send
I have Ehlers Danlos syndrome and have a huge problem with medication. I cannot take medication on regular basis as I will have anaphylactic shock by the 5th or 6th dose. I cannot wear perfume or use anything with scent in it and I have reactions to walnuts . Can you tell me what’s going on in my body ?
I also have EDS and it is very common for us to have another another comorbidity like MCAS, POTS, and gastroporesis.
I get histamine intoxication from any kind of food: (super slightly fermented) pineapple, for instance. And it’s not just for a few hours, either. But then, I’m histamine intolerant, very much so, have been from birth, though my symptoms didn’t have a name back then.
It could be Salicylate sensitivity too ....
Do you think the High Histamine levels could have to do with one or a few forms of the 60 forms of the EBV which we have seen has made its way out of Dormancy since Covid 19 came to light?
Urticaria is involved with histamine how? I looked like multi continent person. The allergist thought I had a little angioedema to boot. Food Intolerances App. is the way I learned what I shouldn’t eat and taking vital nutrients Aller-C which is a blend of C, quercitin, and bromelain if I’m remembering correctly.
Great to sprout beans but then so far you don’t mention how to use them when they are sprouted. I notice how you pronounce the name Zoe and I grew you with that being a family members name and the E was silent with the O being a long vowel so it sounds strange to me when you saw both vowels as long sounds.
I’ve suggested to my neighbor to do a food elimination trial..she refuses..she went to Dr yesterday and they do their typical treatment..prescription drug of prednisone and cough syrup. She’s 94 and takes numerous medications. She had allergy testing done a few years ago.the list was long…which signals leaky gut…It’s insane.
I've had histamine intolerance resulting in extremely itchy hives and angioedema. Luckily it is now in remission.
Any tips? 🙏🏻
@@Kukkema When I had a flare up, I went on a low histamine diet, and took loratadine or fexofenadine 2x a day. As it was calming down, I started introducing more foods, and eventually stopped taking antihistamines. I'm sorry I don't have any better advice. I believe it's stress related, I'm trying to manage my emotions better and look after myself. I also have thyroid problems so that forces me to look after myself and luckily the hives haven't appeared in a long time. I hope you get better very soon too 🤗
I cut salt, feeling better..
Please , do a show om mcas!! There's more and more people susceptible now with all reinfections of covid. I need my Dr to be more aware
The suggestion of using pea sprouts seems to have caused a lot of discussion about possible negative effects on gut health. Also, I am unsure if the DAO is in the seed or in the shoot - most people seem to use the shoot only in recipes, so would that solve the problems some people are suggesting in the comments?
Oh my goodness, could it be that all my food intolerances, allergies and leaky gut are the cause of my Lichen Sclerosus (hormone related)?? The histamine disturbes my oestrogene .....
Hmm. I wonder if this is why I still can’t drink alcohol 4 years after first getting Covid. Headache, sore throat, sinus irritation feeling, and very sleepy, slow thinking, after just a tiny amount?
I do fine with all those other histamine heavy foods though. So maybe not?
Do you sprout and then cook the kidney beans? Cuz I've heard that raw kidney beans are unhealthy
Mine came after a hysterectomy- related to hormones - my life is a living nightmare 😢 My neuropsychiatric symptoms are awful xxx I definitely have mass cell activation syndrome
Been waiting 5 decades for this information. STOP WITH THE NERD OUT WARNING PLEASE. Just give the information clearly and leave us to do the rest.
I enjoy the style of presentation including the "nerd outs" ! Yes health is a serious topic but the presentation is relaxed, fun and entertaining. Better than just giving us boring facts and words we cannot pronounce. I enjoy the Zoe presentations. They are onevof the few health videos I watch all the way through. Thank you Zoe team! ❤
The DAO that I buy is not expensive.
Think of Histomine like a bucket , if your Histomine bucket is full it overflows. Try a low histomine diet. Eat antihistamine foods, Histomine release foods, histomine blocker foods and histomine balancing aminos like trimethylglycine
Which proteins or meat have histamine????
Does Histamine intolerance cause hives or also pruritus?
What about hot and cold sweats and flushes?
Would histamine intolerance cause poor or delayed wound healing?
So if histamine is so important in the body is regular consumption of anti histamines a bad thing? I take cetirizine every day to minimise my sinus symptoms and also to perhaps prevent recurrence of urticaria?
I've heard that anti histamines reduce DAO levels, but research it as well to make sure.
If you get an answer to this question I’d also like to know
I would also like to know the answer to this question as I’ve been taking antihistamines daily for years.
Does any one get a burning red face shortly after eating? I feel like my face has prickles coming from the inside to the outside of my face. I get very hot and red too. Now that I am experiencing menopause, the hot flashes are different. Hot flashes are just a flush with no burning or prickles. I am pretty sure it's histamine with the prickles as it always happens very shortly after eating.
Others seem to lash out about the 'nerding out' but for me, Jonathan laughing on the WHO advice... Well, there are people struggling to make the ends meet. Beggers can't be chosers. If there's a bit smelly serving of fish, you'll at least try it. You cut out the green parts of a potato and eat the rest of it. Yes, I'm completely aware of the risks on both of these.
Can (Hydrogen) SIBO also cause Histamine intolerance? And does Dermographism have anything to do with it?
Yes, some bacteria produce histamine themselves
About 20:years ago, I ate some crabs and got hives afterwards. My first thought was that, unfortunately, I had developed an allergy to crabs. I googled, cuz that’s what you do, and read that crabs - when they are starting to go bad - will produce a histamine, and if you eat a crab at that point, you will react to the histamine.
📝 Summary of Key Points:
📌 Histamine intolerance is a condition where individuals have a hypersensitivity to histamine, often due to impaired DAO enzyme activity in the small intestine.
🧐 Symptoms of histamine intolerance can vary widely, affecting different parts of the body, and typically include abdominal bloating, headaches, skin issues, and more.
💡 Additional Insights and Observations:
💬 Quotable Moments: Histamine is essential for bodily functions but can cause issues when imbalanced, leading to conditions like histamine intolerance.
📊 Data and Statistics: Research suggests that around 1 to 3% of the population may have histamine intolerance, making it a significant health concern.
📣 Concluding Remarks:
Histamine intolerance is a complex condition that requires a holistic approach to diagnosis and management. Understanding the role of histamine in the body, identifying symptoms, and following a low histamine diet can help individuals improve their gut health and overall well-being. It's crucial to address underlying gut health issues and work towards restoring balance for long-term health benefits.
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I have not DAO problems but my B histamin is 170. Normal is around 9. I am itching in my face sometimes legs. What I figure out was that salt makes me crazy- itching. Maybe somebody need to hear about salt.
These interviews would flow so much better if Jonathan would not interrupt and talk so much. Just let the guest speak uninterrupted. We are not babies - we can follow a lecture without the unnecessary "clarification" comments from Jonathan.
Key takeaways = there is a Veg alternative to DAO. Unfortunately this episode did not help me as someone suffering with histamine intolerance.