Pacemaker potential | Cardiovascular (CVS) Physiology mbbs 1st year

Physiology lecture on pacemaker potential is also known as 'nodal action potential'
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[@adityatripathi9905]

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Awesome. Loved it

[@munimed]

Same 😂

[@ajhad246]

Man of culture 👏👏👏

[@arvindhkumar819]

Very good explanation Mam👌😁.. An hour of reading in Books was made clear by Minutes of ur lecture Mam:)

[@PhysiologyOpen]

Glad to hear that

[@roopalgupta7256]

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[@PhysiologyOpen]

All the best for exam. Thanks and welcome

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[@PhysiologyOpen]

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[@mrunalpansare5903]

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[@PhysiologyOpen]

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[@zamanafi8232]

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[@PhysiologyOpen]

Greetings from India. Thanks for the support

[@user-ml5of3jh9f]

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Relly amazing and simplified explainations
Thank you a lot

[@PhysiologyOpen]

Oh my God…big compliment…thank you so much 😊

[@sksoni9023]

VERY GOOD EXPLANATION

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[@bakhshinjalal5245]

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[@PhysiologyOpen]

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[@PhysiologyOpen]

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[@dineshmule6986]

you are great mam. keep going and make videos like these.

[@PhysiologyOpen]

Thankyou so much for liking 😊 and the compliment 🤗

[@Minnie123.__.]

Thank you so much you explained everything so well!

[@PhysiologyOpen]

thanks

[@laithhaidar6220]

Thank you so much doctor 👩‍⚕️ I love this lecture and study from it now 💙🌹

[@PhysiologyOpen]

Glad you enjoy it!

[@sabahnargis9767]

Thankyou for such a simple and precise explaination..highly appreciated mam.❤

[@PhysiologyOpen]

Most welcome. Thanks 😊

[@shoreofanatomy8346]

Mam it was amazing.
Thanku for such superrrbbbbb explaination

[@PhysiologyOpen]

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[@83mahamtahir63]

Best explanation..
I usually don't comment on CZcams video..
But ur video is amazing..
Thank u so much💖💖💖💖💖💖
Make more videos plz .. 💖

[@PhysiologyOpen]

Thank you so much..for an exclusive comment for Physiologyopen

[@yiguy5ed6ugh8h7]

Thanks for crystal clear explanation really appreciate you work ❤

[@PhysiologyOpen]

Glad it was helpful!

[@anderaalvince4228]

I'm so happy I found this,be blessed

[@PhysiologyOpen]

So glad! Keep learning

[@bunnythecat6552]

Very clear and easy explanation thank you mam😊

[@PhysiologyOpen]

Thanks...love when people understand the topics

[@emimaananth3886]

Maam....very clearly xplained....thanku a lot

[@PhysiologyOpen]

Happy that it helped

[@nethran7938]

Glad I came across this :) thank you so much!!

[@PhysiologyOpen]

Most welcome

[@prathamdoshi1527]

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[@PhysiologyOpen]

Thanks

[@sagaralluri3571]

Nice explanation thank you

[@PhysiologyOpen]

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[@munazzaarshad2455]

Excellently explained 👍🏻

[@PhysiologyOpen]

Thankyou

[@anuradhayadav7179]

Very nic, keep it up

[@PhysiologyOpen]

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[@Shahshweta1902]

Very simplified 😊 thanku ma'am

[@PhysiologyOpen]

Thanks for liking

[@binduganne4866]

Ur vedios are simply superb mam,can u make a series on C.N.S PHARMACOLOGY

[@PhysiologyOpen]

Will try... many topics are already lined up...will do for sure but will take some time...

[@radhakrishnanravichandran534]

Awesome explanation mam...tq mam...plz make video on special senses physiology mam

[@PhysiologyOpen]

Now switching to endocrine physiology. Special senses will follow

[@PhysiologyOpen]

Comment below: Why SA node has highest rate of impulse generation among autorhythmic cells ? Answer lies in the pacemaker action potential....

[@iazahussainzz]

cells in the SA node have a higher conductance for sodium ions, so they continually fire leading to more frequent action potentials

[@PhysiologyOpen]

Yes, the rate is higher than other pacemaker cells like AV node (they also have pacemaker potential), because the prepotential slope is steeper in SA node because of higher conductance

[@iazahussainzz]

@@PhysiologyOpen it was a good video, thank you

[@PhysiologyOpen]

@@iazahussainzz Thank you, appreaciation helps

[@irenetheresathomas1714]

Thankyou Ma'am. This is really helpful

[@PhysiologyOpen]

Glad it helped. Keep learning 😊

[@jmjm3882]

Very well explained, thank u ma'am!

[@PhysiologyOpen]

My pleasure 😊

[@singtothecreator2720]

Really great mam

[@PhysiologyOpen]

Thanks 😊

[@ajaytripathi4026]

Very good explanation...... Thanx ..... 🙏🙏🙏🙏

[@PhysiologyOpen]

Thanks for liking

[@sawantsingh522]

Thank you mam for such an excellent explanation 😍😍

[@PhysiologyOpen]

So glad

[@vardhankalisetti7620]

Mind blowing ma'am

[@PhysiologyOpen]

Keep watching

[@yogeshmali8473]

Thanks mam for such simplified video..🙏

[@PhysiologyOpen]

You are welcome 😊

[@krishnachaurasia-c8e]

6:00 mam why it's called hyperpolarized hcn since it's too moving towards positive or it's behaving like funny current..

[@Pratikkumar-ri9sp]

thank you mam
it is very helpfull🙏🙏🙏

[@PhysiologyOpen]

Glad that the video helped

[@ObodoechiOluchi-km5xv]

Very good explanation❤

[@PhysiologyOpen]

Thank you 😊

[@RafiRafi-tg1xj]

Excellent teacher

[@PhysiologyOpen]

Thank you

[@faheemmohammed6384]

Fantastic class

[@PhysiologyOpen]

Thank you

[@aisharasool4598]

Again a great video mam ...thanks alot,,,👍

[@PhysiologyOpen]

Most welcome 😊

[@subhamkarmakar3320]

Just awesome👍

[@PhysiologyOpen]

Thanks a lot 😊

[@johnweak3198]

Excellent. Thank u so muc

[@PhysiologyOpen]

Pleasure is all mine

[@likhamonihazarika1400]

Thku very much maam.. 😇

[@PhysiologyOpen]

Pleasure is all mine

[@Namaskaram_114]

Thank you mam
For wonderful and clear explanation 🙏🏻😊

[@PhysiologyOpen]

Most welcome 😊

[@anuradhayadav7179]

Very Nice . Keep it up

[@PhysiologyOpen]

Thanks for liking 😊

[@user-ry1ds3sc8e]

thanku so much dear mam,lots of love and respect for you mam ♥️♥️❤️❤️🙏🙏🤗🤗

[@PhysiologyOpen]

Thank you so much 😊

[@dr.dhesikan7862]

Nice lecture mam

[@PhysiologyOpen]

Thank you 😊

[@45d.poornachandu84]

Mam your lectures are helping me lot for University exams

[@PhysiologyOpen]

Great! Keep learning

[@radhakrishnanravichandran534]

Awesome explanation mam..tq mam

[@PhysiologyOpen]

Thanks

[@GurpreetSingh-uf6gp]

If the pottasium ions are going out of the Membrane then how are they recovered?? Won’t they be finished

[@PhysiologyOpen]

Movement of very few ions in the range of 1/300000..causes changes in membrane potential. Moreover, sodium potassium ATPase always works and with change in any ionic concentration, it starts working even faster

[@68_purveshpatil86]

Amazing

[@PhysiologyOpen]

You are

[@thecordialcorner6634]

Great mam

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Thanks

[@mohammadasifpatel748]

Thanks ma'am

[@PhysiologyOpen]

😊

[@12-rishitha20]

Thank you mam u made it easy😊😊

[@PhysiologyOpen]

Happy that you liked the video. Keep learning

[@myselfris]

So much thanks...😘😘.. For the video...

[@PhysiologyOpen]

My pleasure

[@modiudit8627]

I don't understand why do you have less number of viewer even you are making easier concept videos... Problem lies in CZcams suggestions.. 🥺

[@PhysiologyOpen]

Hmm...what to say...do share the videos, it will be of help

[@modiudit8627]

Sure.. My pleasure

[@arunabhadasgupta685]

Mam very good explanation

[@PhysiologyOpen]

Thanks

[@tejaswireddy4702]

Thank u so much mam 😊

[@PhysiologyOpen]

Thank you too

[@bublisoniyak6227]

Thank you so much ma'am ❤️

[@PhysiologyOpen]

Most welcome

[@travelshots5881]

Ma'am you makes it too easy to understand 🙏🙏🙏 ma'am can you upload a video about ANS distribution on heart and controlling the heart (sympathetic and parasympathetic nerve fibre) pls ma'am 🙏

[@PhysiologyOpen]

Thanks for appreciation. Will try to upload.

[@preetibugana5772]

Thank you so much ma'am 🙏💓💓

[@PhysiologyOpen]

Most welcome 😊

[@srinivasachakradharearni6328]

Thank you mam

[@PhysiologyOpen]

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[@062_arundhathypkrishna8]

Thank you maam

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My pleasure

[@mbohhonorine8470]

Thank you so much

[@PhysiologyOpen]

Most welcome

[@saikarri4101]

Such a wonderful explanation mam ❤️

[@PhysiologyOpen]

Glad you liked it 😊

[@that_mbbs_nerd]

Madam today is exam.. it's 2am... Yeh 5mark ka ques smjh hi nhi aa rha tha
Thanks to u.. ab aa gya
I wish professors bhi Aisa pdha dete instead of using ppt

[@PhysiologyOpen]

Best wishes for exam

[@kulsumnaqvi1834]

Superb explanation mam

[@PhysiologyOpen]

Thanks for liking Kusum 😊

[@kulsumnaqvi1834]

Wlcm mam

[@user-fi8bm4mc8d]

Helpfulllll confusion dur

[@PhysiologyOpen]

😊👍

[@basildasbaby4666]

Thank you ma'am

[@PhysiologyOpen]

My pleasure

[@jaypaliwal6374]

Superb mam

[@PhysiologyOpen]

Thanks Jay

[@udayaseelan6485]

At the end of phase 3 , the potassium has moved outside the cell, also sodium and calcium has moved inside the cell. So, how does the next cycle of action potential generate?
Can anyone explain please.

[@PhysiologyOpen]

NaCaATPase moves Ca out of the cells. Na K ATPase throws Na out and brings K in

[@udayaseelan6485]

@@PhysiologyOpen thanks a lot, mam. ✨

[@PhysiologyOpen]

😊

[@mgambigamba5047]

Best video 🤗

[@PhysiologyOpen]

Thanks

[@jayanth3051]

Nice mam

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Thanks

[@karishmasawhney21]

amazing maam! new subscriber :)

[@PhysiologyOpen]

Thanks for liking and subscribing

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Thank you mam 🙇🏻‍♀️

[@PhysiologyOpen]

Most welcome 😊

[@fatimahkadiku7368]

Take ur flowers 🌷🌷💐

[@PhysiologyOpen]

So nice of you

[@brilliantfuture1841]

Please answer me , the funny channels are permeable to sodium and potassium ions in the the same time ,,,,so the funny current is a complex of sodium and potassium ions current ,sodium inward ,but what about potassium,inward or outward ,please answer,I really need your help.

[@PhysiologyOpen]

Potassium moves outward

[@brilliantfuture1841]

@@PhysiologyOpen Thank you very much mum🥰🙏🏻🙏🏻🙏🏻🙏🏻

[@Dr.Abisha]

Thanku mam🥰

[@PhysiologyOpen]

Happy to help..always

[@madhawalakshan4025]

Can you give your link for mechanism of heart rate which you tell in this video,( you tell it when you tell about cAMP and funny channels)

[@PhysiologyOpen]

czcams.com/video/w7UozvV8Kf0/video.html

[@madhawalakshan4025]

@@PhysiologyOpen thank you madam

[@abirdebnath7827]

wasted an hour reading the book😞, this 8 minute video cleard everything

[@PhysiologyOpen]

Book reading never a waste. But I am glad I was of help Hope my other videos help you too.. Best of luck

[@johnabbas5722]

Happy diwali mam 🎇🎆✨

[@PhysiologyOpen]

Happy Diwali to you and your family

[@biggboss3946]

hi
on which resources did you make this video ? and what makes the cycle to repeate itself ?
didn't the Na+ and Ca+ got inside and the K+ went outside ? How is that repeated ?

[@PhysiologyOpen]

Resources used for all videos
Basic: Guyton and Ganong
Above them: Sherwood
Neuroscience over and above: Kandel
Hematology: Wintrobe

[@goldensongs6981]

How do Ca2+ ions get out of that cell?

[@PhysiologyOpen]

Ca2 ATPases...and sodium calcium exchanger

[@karthikeyan7372]

Nice

[@PhysiologyOpen]

Thank you 😊

[@RealNepal2023]

❤❤❤❤

[@PhysiologyOpen]

😊❤️

[@harika387]

Mam, please can you do video on regulation of cardiac and respiratory system please mam?

[@PhysiologyOpen]

Yup will do, it will take some time though...already have a series of videos lined up

[@maasivaiahvelivela7765]

What about contractile cells graph ?Madam ...

[@PhysiologyOpen]

Have to make that video

[@sundarloganathan7042]

what is the fate of sodium entering during the prepotential? Phase 4

[@PhysiologyOpen]

Fate means? Whatever sodium enters is thrown out by sodium potassium ATPase

[@ahmetttung]

Wasn't depolarization at phase zero with T-type calcium current?

[@PhysiologyOpen]

Yeah true...so what’s the question?

[@ahmetttung]

But L-type calcium that raises from -40 mV to +10 mV

[@PhysiologyOpen]

That’s also depolarisation. Depolarisation is any change in potential towards positive..when it crosses threshold it is action potential (which is always depolarisation)

[@ahmetttung]

Understood. Thank u so much mam 😊

[@valentinemenso8375]

Give references books for these lectures please i beg

[@PhysiologyOpen]

For all lectures Guyton and Ganong

[@yokeshkaliaperumal2012]

Hello mam. There is a sentence given in G K Pal Textbook of Medical Physiology on pg. 554 which states as follows
" Actually, it is the resting membrane potential that automatically depolarizes to form the pacemaker potential. Thus in pacemaking tissues there is no resting membrane potential, rather the pacemaker potential is the restless membrane potential.
But isn't the resting membrane potential of pacemaker tissue also know as the pacemaker potential? Can you please explain mam?

[@PhysiologyOpen]

It’s two different ways of saying same thing

[@sksharma6104]

That funny current explanation.... Ohh God.... I can't forget that.... HCN channel....

[@PhysiologyOpen]

Great...keep going 😊

[@panda-pw6eg]

🤗

[@PhysiologyOpen]

😊

[@truthfacts6343]

Mam u r teaching wrong there is no sodium in pacemaker tissue itz only potassium and calcium

[@PhysiologyOpen]

Did you listen to the video

[@PhysiologyOpen]

I have spoken about calcium only

[@80.subhadipsaha8]

Thank you mam

[@PhysiologyOpen]

Most welcome 😊