Lab-Grown "Mini-brains" Perform Non-Linear Computation, Eat Neurotransmitters, & Go To Space
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- čas přidán 23. 11. 2023
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Human brain organoids ("mini-brains") are being grown in labs around the world. They're being fed neurotransmitters, competing with AI to solve non-linear equations, and going to space to study the effects of microgravity. This video reviews three preprints, preliminary reports of new scientific studies. (My AI voice caught a cold this week.)
Support the channel: / ihmcurious
Preprints:
- Brain Organoid Computing for Artificial Intelligence (Cai et al.) www.biorxiv.org/content/10.11...
- Modulation of neuronal activity in cortical organoids with bioelectronic delivery of ions and neurotransmitters (Park et al.) www.biorxiv.org/content/10.11...
- Studies on the International Space Station to assess the effects of microgravity on iPSC-derived neural organoids (Marotta et al.) www.biorxiv.org/content/10.11...
Videos:
-SpaceX: CRS-19 Mission • CRS-19 Mission
-NASA: What Launches to Space on SpaceX’s Next Cargo Mission [CRS-18] • What Launches to Space...
-todo314: Henon attractor • Henon attractor
Other Media:
-Resting potential image: openstax.org/books/biology-2e...
-GPU slide: 15418.courses.cs.cmu.edu/sprin... - Věda a technologie
![Are Brain Organoids Conscious? AI? Christof Koch on Consciousness vs. Intelligence in IIT [Clip 4]](http://i.ytimg.com/vi/fEULMhfzPeQ/mqdefault.jpg)
Make them pass butter and I'll be impressed
PR: what is my purpose?
R: to pass the butter.
PR: oh god!
If math wasn't torture enough, now the brains have to do it in a petri dish... sounds familiar, like school.
And here we arer going full circle. Naturally developed brains develope devices running on anorganic matter just to discover that organic matter is just better. I am sure they will just add to this and discover a fully automated version of an organoid some day in the future. To make it easier they will encase it in a hard shell, give it limbs to interact and sensors to understand. Then after many iterations they will end up at humans
thats never gonna happen because a human contains one thing that cannot be replicated with developing body parts from stem cells ii soul
@@esatacikgoz2016fascinating. So when they make the humans with no souls and compare them to the ensouled humans, maybe they'll finally see where you're hiding those people things and make sure they get attached in the future
@@esatacikgoz2016
So you decide who does and does not have a soul?
Love seeing my instructor become a successful CZcamsr with sponsorships. Keep up the great work. I always look forward to learning from your videos.
Fewer rounds of training and just the complexity of the system. Thank you for sharing, this is amazing
This channel is so underrated♥
Next phase of developing computers.
Gonna wait till this is oeer reviewed to state my opinions , I'm really hoping that the increased maturity due to space travel is true. Cause my childhood self just wanna say Cosmic Rays or something.(even though I know the space shuttles are shielded.😅)
Wow never knew the human vs computer processing battle is still raging on.
Great stuff!
Cai's brain-o-ware was published in Nature Electronics: Article
Published: 11 December 2023
Brain organoid reservoir computing for artificial intelligence
Hongwei Cai, Zheng Ao, Chunhui Tian, Zhuhao Wu, Hongcheng Liu, Jason Tchieu, Mingxia Gu, Ken Mackie & Feng Guo
Nature Electronics volume 6, pages1032-1039 (2023)
Hey watched your videos last year glad to find this channel again
Brilliantly presented - thanks.
Do these mini brains have everything a human brain does, like a hippocampus and occipital cortex, but miniature?
Nope! They're relatively disorganized blobs of brain tissue. Check out this video for more of an introduction: czcams.com/video/u6FGq7_t3Eo/video.html
@@ihmcuriousis there a scenario where we can grow these blobs with that level of organisation
If so does that mean we'll ne stuck with the types of regions in the brain or will we be able to make a "brainoid" with regions for more specialised tasks ?
@@ihmcuriousuhm hey, the discord link doesn’t work… u got a fresh one maybe?
Refreshed
Specialization and new brain regions never before imagined are possible
this is horrifying
I’m like this is terrible! Show me more 👀👀👀
How is this horrifying lol
@@nulled7888 yeah, same. it's hurting my head trying to understand
@@nulled7888exacly lol
I have a difficult time holding back vomit thinking over this
Very well-explained and interesting!
"[...] brew beer in space. Both admirable goals" 😂 I feel you
Well done
I swear to god that thumbnail is making me see things
Why doesn't Anheuser-Busch start with brewing beer on Earth before doing it in space? Shouldn't they first start with the easier process?
As a computer engineer I want to go back and do brain related grad as well now 😂
soon you’ll be able to enjoy a nice cup of coffee, plug into your brain, and enjoy the video game Scorn.
very exciting stuff!
hold on a minute... does this imply that we *could* potentially teach people math problems this way?
If so, we literally just created the basis of installable knowledge
matrix moment
Looks like it
No, probably not. Molecular geneticist here (Biologist). The way these organoids are taught to do problems is by having them attach to certain electrodes, which then feed them electrical pulses. The electrical response to these signals is then measured at another electrode, and when the neurons working together give us a response we like (the right answer) we reward them chemically, causing the neurons to plastically change connections so they produce the signals we like.
The thing is your brain doesn't work that way. When we see a math problem, it passes from our eyes to our brain as visual information, then our brain decodes the meaning via the cooperation of millions of neurons. You don't have one nerve that carries all of the math problem as easy to read pulses for the organoid to attach to. It's spread through your whole brain. The same goes for the answer, the only time that ALL the information comes together again is when your brains starts trying to communicate it. Which is again a task done by thousands of neurons.
On top of that, even if we could figure out how to attach it in one person, it would only work for one person. General brain structure is conserved across all humans. But the exact placement of neurons is not. Imagine two identical valleys that are settled twice be different people. You'd probably get similar cities, but the exact place each building and shop is put would probably be quite different
On top of that there is the practical issue: doing brain surgery on yourself to avoid doing math homework is probably not worth it.
So have these guys grown big, and then make a bunch of AI robots too, and then have them fight and beat AI
cool 😎
how long to grow ??.. how long they will survive ??..
This research will be very cool until its scary.
the big problem with replacing digital neural networks with biological ones is that digital ones can store their state once trained and be duplicated infinitely as long as you have enough hardware. biological networks must be trained individually. until brains can be copy pasted this approach will not be viable.
What could happen if the mini-brain cells was harvested from the brain of a serial killer ?
Hey, who's here for class? What class is it? Welcome, class!
This is pretty badass but I hope the bad guys don't get it
The WAU.
They are going to beat A.I. hands down!
❤🎉🎉
First
ah sweet , man made horrors within my comprehension
Spy Kids
Head cheee
The only thing more next generation than 7:44 would be Bitcoin. Thank me later. Or fly a rocket to turn back time and send me some from the past.