Diabetic nephropathy - Mechanisms | Endocrine system diseases | NCLEX-RN | Khan Academy

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  • čas přidán 13. 05. 2015
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Komentáře • 108

  • @jacquelinecook5613
    @jacquelinecook5613 Před rokem +80

    My oldest son is in his early 20's and he has type 1 diabetes. But thank God for this piece of article czcams.com/users/postUgkxVYhghKWmrUgXARZ_ydZTvmmcrw5L0I5i At first he thought he had the flu and was lying down on the bed for three days until his sister took him to the hospital. They took his blood and it was 600. What I do not understand is how he could have gotten it, since no one in the family has it. But he is winning the battle now. This is good stuff.

  • @clairemonaghan9684
    @clairemonaghan9684 Před 9 lety +1

    Fantastic! Thank you!

  • @fayyazyounus1585
    @fayyazyounus1585 Před 2 lety +8

    DM causes hyaline arteriosclerosis in the efferent arteriole causing increased filtration.
    Very well explained. Thank you

    • @HabibUrrahman-vy6dh
      @HabibUrrahman-vy6dh Před rokem

      So basically what you are trying to say is that's responsible for Hypertension?

  • @zeinabghamlouch9920
    @zeinabghamlouch9920 Před 4 lety +2

    Very well explained and illustrated, thank you so much this was really helpful

  • @mariac7394
    @mariac7394 Před 2 lety +2

    Thank you for going into great detail!

  • @annawright4545
    @annawright4545 Před 2 lety +2

    Thank you, so much. To me it was clearly hearable (in reference to another comment bellow) and I do appreciate that you did not gotten lost in details you have presented in other VDOs (about the damage mechanism).

  • @jalalalakhras4113
    @jalalalakhras4113 Před 8 lety +2

    Thank you very much man,, very very helpful

  • @Habe111
    @Habe111 Před 7 lety +2

    This is peeeerfect, thank youu

  • @PaulusLeThien
    @PaulusLeThien Před 7 lety +1

    Thx! Very well explained!

  • @sopiaahmad7795
    @sopiaahmad7795 Před 7 lety

    thanx for advice,God bless you

  • @sbusobantu1490
    @sbusobantu1490 Před 9 lety +2

    Thank you so much

  • @lifeofachristiannursingstu9498

    Thank you so much. I finally understood after a week of reading and lectures.

  • @marconeill2229
    @marconeill2229 Před rokem +1

    Clearest explanation of CKD and its cause! Thanks!
    Would love to see your "powers of explanation" used to outline the latest research into reversing CKD or better treating it? (eg SGLT2, GLP-1 etc) - the current explanation of which I find impenetrable as a lay person!

  • @RoshanLovesall
    @RoshanLovesall Před 3 lety +1

    Very Clearly explained the concept. Really Good. Continue the good work

  • @KloiKoch
    @KloiKoch Před rokem

    Thank you for this great detailed explanation! Even for me, who is not a medical student, it is easily understandable!

  • @haythemayachi3384
    @haythemayachi3384 Před 7 lety +11

    this is eactely what i was seraching for !!
    thank you very much :DD

    • @danielatomescu3487
      @danielatomescu3487 Před 4 lety

      hey ,if anyone else wants to uncover
      natural cure for chronic kidney disease
      try Franaar Healthy Kidney Formula (just google it ) ? Ive heard some interesting things about it and my brother in law got excellent success with it.

    • @sergioescalona62
      @sergioescalona62 Před 4 lety

      Cheers for the Video clip! Apologies for chiming in, I am interested in your thoughts. Have you heard about - Zeyames Wonliver Breakthrough (do a search on google)? It is a great exclusive product for discovering the simple way to end diabetic nerve pain and neuropathy without the normal expense. Ive heard some super things about it and my work colleague finally got amazing results with it.

  • @Haipha99
    @Haipha99 Před 3 lety

    wonderful. thank u

  • @lifeisbeautiful7047
    @lifeisbeautiful7047 Před 4 lety +1

    Perfect 👏👏👏

  • @pou2965
    @pou2965 Před 3 lety

    Amazing🔥

  • @skasifali8627
    @skasifali8627 Před 3 lety

    It is very helpful 😍

  • @josejoao1621
    @josejoao1621 Před 2 lety

    Amazing!

  • @leavinoneday
    @leavinoneday Před 3 měsíci

    Wow I really like how u explain

  • @jean.lucstrack8706
    @jean.lucstrack8706 Před rokem

    Brilliant explanation

  • @somewherealone226
    @somewherealone226 Před 4 lety

    Perfecto 👌

  • @drhouse9801
    @drhouse9801 Před 4 lety +4

    the reason for efferent arteriolar vascular lumen narrowing is not vasoconstriction , it is hyaline artriolarscelerosis

  • @sreynethpav2365
    @sreynethpav2365 Před 6 lety

    best working .and i would like to see diabete neuroparty .can you make it?

  • @HafizahHoshni
    @HafizahHoshni Před 7 lety +2

    Your videos are very helpful. Thank you :D

    • @Celestenshi
      @Celestenshi Před 7 lety

      Rеversе Diаbеtes with a “Раnсreаs Jumрstаrt” twitter.com/385c9d4a1ae33a7b8/status/804558352671973376 Diаbetiс nеphrораthу Mechаnisms EEЕndоcrine sуstem disеаses NCLЕХ RN Кhаn Aсаdеееmy

    • @afreenmukadam5796
      @afreenmukadam5796 Před 7 lety

      “I Can’t Believe it Wooorked!” Natural Triсk tо Reveeeerse Your Diаbetеees => twitter.com/0a7e93d52b9720ff3/status/804558352671973376 Diabetic nеphropathy Mechanisms Endocrineee systеm disеases NCLEX RN Khаn Academу

    • @Xnnye
      @Xnnye Před 7 lety

      Fоoоrсe Your Panсreаas tо Fiхxх Your Blooоood Sugar (Natural Мethod) => twitter.com/fa5a84e5713076424/status/804558352671973376 Diabetiс nеphropаthу Мechаnisms Endоcrine systеm disеasеs NCLЕX RN Khааaan Acаdemy

  • @ofitlhileruxralenyena1230

    perfect.. God bless you.. this is exactly what I was looking for

  • @brudforce
    @brudforce Před 8 lety +2

    Please provide literature source for activation of RAAS in diabetic nephropathy!

  • @holkangel
    @holkangel Před 9 lety +13

    This is a beautifully done, clear, concise and well illustrated. Thank you.
    I do have some critique still - I could barely hear you. Also, I think you did not really explain the pathological changes which happen in the arteries and arterioles of the kidney (as in the lesions of these)... some lesions which lead to glomerulosclerosis? Or maybe you did but without the nomenclature which is used? :(

    • @aleksandarmirchev5792
      @aleksandarmirchev5792 Před 6 lety

      hi everyone ,if anyone else wants to discover
      what is a kidney disease
      try Franaar Healthy Kidney Formula (do a search on google ) ? Ive heard some super things about it and my brother in law got cool success with it.

    • @ygatesatellite4964
      @ygatesatellite4964 Před 6 lety

      Not certain about the points made but ,if anyone else wants to uncover
      disease of the kidney
      try Franaar Healthy Kidney Formula (do a search on google ) ? Ive heard some amazing things about it and my m8 got amazing success with it.

    • @yasminfaria170
      @yasminfaria170 Před 6 lety

      Dominique রবিদৃনাহ সঃগিত

    • @georgiosantonopoulos7893
      @georgiosantonopoulos7893 Před 5 lety

      Appreciate Video clip! Excuse me for the intrusion, I am interested in your initial thoughts. Have you thought about - Trentvorty Perfection Kidney Theorem (Sure I saw it on Google)? It is a great one off guide for improving kidney function without the hard work. Ive heard some pretty good things about it and my buddy at very last got great success with it.

  • @borafrusciante3328
    @borafrusciante3328 Před 7 lety +10

    Great video, good explanation, but i could hardly hear her voice :(

  • @samzu9626
    @samzu9626 Před 6 lety

    hi thanks alot . why do GFR decrease in the stages of DKD

  • @unknownperson-pt7bf
    @unknownperson-pt7bf Před 4 lety

    How a wonderful video 🌹🌹

  • @arunanirudhan1812
    @arunanirudhan1812 Před 5 lety +2

    Thank you very much for this mind blowing information.I have one question.....you described about RAAS,its mechanism is vasoconstriction in efferent arteriole when there is renal perfusion right..Then why it’s get activated during increased glomerular filtration¿

    • @fahadafridi8173
      @fahadafridi8173 Před 3 lety +1

      Watch at 7:10 he explains that the etiology is not known but they think it might have to do with the fact that hyperglycemia some how activates RDA system

    • @annawright4545
      @annawright4545 Před 2 lety

      I see you have asked this 3 yrs ago - but I am here just now and taking a chance to have a reason "speculated" out on it: perhaps this is a defensive mechanism where the kidneys choose the less worse scenario by trying to stabilize the post glomerular (afferent) blood-pressure and to "push back" against the increased filtration. This - if I think of kidneys as organs actively regulating the hydraulic side of the main blood pressure. AND/OR: it is a direct and swift way to flush out excess glucose (since the Renin is triggered by high blood sugar in a direct and immediate short circuit in the kidney).

    • @HabibUrrahman-vy6dh
      @HabibUrrahman-vy6dh Před rokem

      @@annawright4545 the basic question that I have is how does hypertension develop from diabetes mellitus although he mentions it as saying that it's a comorbidity ?

  • @memobayomi
    @memobayomi Před rokem

    Brilliant

  • @Ledeluz
    @Ledeluz Před rokem

    I'm really scared since I was diagnosed with dm and checking out what will my end game if it really get worse. I know it's my fault but I really want to fight since I didn't achieve anything in life yet and I'm already 34. I hope I can finance continually my medications to avoid these complications.

  • @ronnynoneofyourbusinessgoo7892

    You are too fast man!!! Speed controls on youtube app SUCKS. Google is the 👿 destroy them

  • @valsartanay7117
    @valsartanay7117 Před 2 lety

    Thanx 🫶🏻

  • @agoogleuser4354
    @agoogleuser4354 Před 3 lety

    This video would be great if the voice was louder by 200%...

  • @university2775
    @university2775 Před 5 lety +2

    Please increase ypur volume while recording. Despite being on maximum volume on both headphones and speakers, your videos can be hardly be heard more often than not.

  • @CarolynDenison
    @CarolynDenison Před 4 lety +1

    I wish I haden't sen this. My doctor called my husband today. I'm waiting for them to call me. I missed his call earlier. Blood work a few day's ago. I have all the symptoms of stage 5 kidney disease. Having extreme pain in my back, and can't stand up. I got a bad bad feeling something bad is up. I'm going to bed.

    • @nishey94
      @nishey94 Před 4 lety

      Carolyn Byrd did you find out what it was?

  • @donraquel
    @donraquel Před 2 lety +1

    😮

  • @kishoremazumdar2004
    @kishoremazumdar2004 Před 4 lety +1

    I think RAAS reponds to low blood pressure. It leads to constriction of afferent arterioles not efferent arterioles so that it can decrease the GFR and maintain the volume of blood and can subsequently maintain the blood pressure. You have explained RAAS increases GFR. Can you elaborate a bit

  • @Safestreet
    @Safestreet Před rokem

    Did anyone hear him say "efferent arteriole" -twice??!

  • @binitamakhim9905
    @binitamakhim9905 Před 5 lety +2

    You are not connecting your explanation to the diabetes.... I was expecting how hyperglycemic state metabolism causes changes in microvasculature

  • @mateuspereira3802
    @mateuspereira3802 Před 3 lety

    Great video, but hearing the narrator whispering was sorta annoying.

  • @leo-lj1to
    @leo-lj1to Před rokem

    you don't talk about AGE

  • @D3cker1
    @D3cker1 Před 3 lety

    You can speak up to the mic you know??

  • @drtanveerahmed3373
    @drtanveerahmed3373 Před 7 lety

    Not clarified properly...

  • @sandeshsharma3560
    @sandeshsharma3560 Před 4 lety

    im thankful for the video..but this is not a makeup tutorial man..just sayin

  • @stephenokwori1882
    @stephenokwori1882 Před rokem

    My heart just keeps thanking you and thanking you Dr Igudia for all you have done for me, you gave me your words that you could heal any sickness or disease, thank you for permanently curing me of my diabetes disease you are amazing.

  • @ronnynoneofyourbusinessgoo7892

    And you are too quiet too

  • @anastasia.2007.
    @anastasia.2007. Před 4 lety +8

    The lecturer almost whispers. What's the point of speaking in such a quiet voice? You don't want to wake up your neighbors?

    • @kabitapun6437
      @kabitapun6437 Před 3 lety

      LOL. I can hear him though :D

    • @azersamaali2016
      @azersamaali2016 Před 3 lety +1

      Thanks for the Video! Forgive me for the intrusion, I would love your thoughts. Have you tried - Chireetler Avoiding Diseases Rule (search on google)? It is a great one off guide for learning how to stop kidney damage minus the headache. Ive heard some unbelievable things about it and my buddy got amazing results with it.

    • @Valentina_-lw9ui
      @Valentina_-lw9ui Před 3 lety

      Winner of a video, been searching for "how does diabetes increase risk of heart attack?" for a while now, and I think this has helped. Ever heard of - Piyatalie Breathtaking Precedence - (do a google search ) ? It is a great one of a kind guide for discovering how to get rid of type two diabetes minus the normal expense. Ive heard some unbelievable things about it and my co-worker got excellent results with it.

  • @salikusmani4665
    @salikusmani4665 Před 7 lety

    Why do you update videos with so less volume? Plz dont upload them and spoil our mood....