There are three human Cdc25 homologues: Cdc25A, B, and C. Cdc25 is a protein phosphatase (cell cycle regulator) important in the activation of CDKs. What they do is remove the inhibitory phosphorylation in Cdks. So cdc25A will activate the cyclin D-CDK4 complex and the cyclin E-CDK2 complex, which will then phosphorylate Rb, which will eventually be important for G1/S progression. Hope that helps!
Good diagrams, nice& interesting explanation
I appreciate you help so much. What a great way to elaborate the topic.
Thanks Renz! Happy to hear it was helpful 🙌🏽
@@EKGScience can i know you're specific ig to ask further questions about the course?
@@renzbryantbalantad1222 Link in the description!
PERFECT EXPLANATION! Thank youu
Thanks Fatema! Glad it helped 🙌🏽
You have such an amazing grasp of the subject. Beautiful video and explanation, congrats!
Thank you, Maria! Appreciate the comment 💙
Thank you !!! So helpful!
Happy to hear it was helpful 😇 Appreciate the comment!
clear and well-explained. Thanks. 😊
Glad it was helpful!
Amazing lecture mam. keep up the good work.👍
Glad you enjoyed it! 🙏🏽
Hello, I have a question, i need to know the role of s cdk on activation cdc25 i hope to get an answer as soon as possible thank u
There are three human Cdc25 homologues: Cdc25A, B, and C. Cdc25 is a protein phosphatase (cell cycle regulator) important in the activation of CDKs. What they do is remove the inhibitory phosphorylation in Cdks. So cdc25A will activate the cyclin D-CDK4 complex and the cyclin E-CDK2 complex, which will then phosphorylate Rb, which will eventually be important for G1/S progression.
Hope that helps!