CYTOKINE SIGNALING Th17 Pathway

Cytokine signaling and Th17 pathway made easy to understand. Blockade of this pathway has been a successful way to treat some immune diseases; it also helps understand some expected and observed adverse effects of the drugs that block this pathway.
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Maria-Dolores Vazquez-Abad, CZcams Cytokine signaling playlist: • Cytokine Signaling
Dis Model Mech. 2012 ; 5(4): 423-433
Microbes and Infection Vol 11, Issue 5, 2009; 625-630
Cellular Immunology Volume 275, Issues 1-2, January-February 2012, Pages 12-18
Blood September 1, 2006 vol. 108 no. 5 1571-1579
Inflamm Bowel Dis, 7: 43-50 (2001) ; Nature Cell Biology 7, 381 - 386 (2005)
Immunology, 93: 257-263 (2001)
Cytokine & Growth Factor Reviews Volume 15, Issue 1, February 2004, Pages 49-60
J Clin Invest. 2005;115(2):282-290
Immunological Reviews, 102: 5-28; 1998
Package inserts of approved biologics
Mol Immunol. 2007;44:2497-2506.
Cellular & Molecular Immunology 2011; 8:447-449
Rev Immunol. 2009; 9, 556-567
Semin Immunol. 2007; 19(6): 400-408.
J Leukoc Biol. 2007):1258-68. Epub 2007 Feb 16.
Immunol Res. 2008;41(2):87-102.
J Immunol. 2008 ;180(6):3746-56.
Immunity Volume 16, Issue 4, April 2002, Pages 559-569
The Journal of Immunology December 1, 1992 vol. 149 no. 11 3495-3502
Nature Reviews Immunology 8, 193-204 (March 2008)
Molec Immunol. 2007;44:2497-2506;
Curr Rheum Rep. 2009;11(5):378-385;
Oncogene. 2000;19:5651-5661;
Nat Rev Immunol. 2007;7:191-201;
Physiol Rev. 2004;84(1):137-167;
Curr Opin Cell Biol. 2009;21(2):262-267.
Fischer S, Garcia KS. Nat Immunol. 2009 December; 10(12): 1245-1251.
Nat Rev Immunol. 2009 Oct;9(10):747
Semin Immunol. 2007 December; 19(6): 400-408.
Oncoimmunology. 2017; 6(1): e1257453.

[@1fhasdfadf]

I want to thank you for this video, no other video on CZcams has explained, carefully, what STAT3 actually does to encourage the differentiation into a Th17 cell. Thanks for your own interpretation of diagrams in the literature as well.

[@maria-doloresvazquez-abad4221]

You're very welcome! Consider subscribing to my channel and sharing; I have created playlists to make it easier for finding specific topics.