DNA Replication | MIT 7.01SC Fundamentals of Biology
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- čas přidán 5. 09. 2024
- DNA Replication
Instructor: Eric Lander
View the complete course: ocw.mit.edu/7-0...
License: Creative Commons BY-NC-SA
More information at ocw.mit.edu/terms
More courses at ocw.mit.edu
What a surgeon. His treatment of DNA replication with sensitivity to physics, mathematics, and biochemistry are more remarkable than most people realize. Dr. Lander, we are truly spoiled
Well you spend 5 years to 8 years in PhD so he is an expert on that
But is not a surgeon ? I think he is a biologist
@@Marco-mw9ky I guess originally he was a mathematician
batman Arkham are you American ?
Holy shit this guy is an incredible professor!
@Qadeer Pashtun isnt this in MIT :)
pure zai it is MIT
Hes is also one of the most influential molecular biologists of our time. Eric Lander rules!
Turns out, there's an enzyme for making it possible for me to learn biology. It's called, Professorrase Eric-Landerase.
That would be *two* enzymes...
😂😂😂😂 Nailed it Friend!
coincidentally ofcourse!
Well said!
😂😂😂😂
Answer to everything occurring inside a cell :
"There is an enzyme for that."
You know if rep-rap or some other 3D printers could print out several smaller versions of themselves, then those smaller 3D printers could print smaller versions and so on (sort of like the broomsticks in Disney's fantasia) until you get to the molecular scale and you can build 3D print enzymes, protein builders, and DNA in a controlled way O_o.
@@aoeu256 is this possible
@@jeevanalexenkavalam6370 no not at all, but, it is in theory possible.
I am now a PhD scholar, on my way to become a lecturer but I still keep coming back to this video, after discovering it in my first year of bachelors. The way Professor Eric makes this inherently complex process sound so simple and harmonious is so interesting. Hopefully, I'd imbibe some of his teachings and pass onto my future students.
Hy you phd scolor why DNA has double polynuclitides i need answer from pakistan
back when they actually teach rather than just reading off a powerpoint
THANK YOU!
David Chen the way this professor teaches is so much more clear and effective. The powerpoint slides a lot of instructors use have too much information for your brain to process. Him writing the information as he tells it to you makes him slow down the information to the same speed as a student can take it in. He’s also very logical and explains the rationale behind things. He seems like an awesome instructor!
@@tasmaniandevil6750 modern topics, especially those in proteomics/biochemistry can't be drawn quickly and the class covers less materials. You can cover much more material in a powerpoint, and students are better prepared for graduate school. If I had to wait for my biochemistry prof to finish drawing all the structures of AA's or other metabolites (especially complex ones like steroids), we probably wouldn't get very far.
Jude K I’m in graduate school right now. And I took undergrad biochem a year ago but you’re entitled to your opinion.
Omg so true nowadays professors just read from PowerPoints which is not helpful at all 😭
This professor is so incridible! He makes it look so simple and interesting, his speech makes me want to learn so much more about this. Thank you so much for posting this, it has helped me so much, i have an exam tomorrow for Molecular Biology. Thank you Prof. Lander
I agree with you
👍
Hi
czcams.com/channels/JwtSCzsltIjEHMmPNDJuHg.html
who reads our dna?
The thing I love about Dr. Lander is that he's so brilliant and accomplished, yet he teaches these topics in a way that's not belittling the intelligence of his students. There are faculty with far fewer credentials who are way more condescending.
Im a politics student and the fact that I watched this whole thing means he is a fantastic teacher. He can get anyone interested in it.
Such a brilliant teacher ! He is not teaching , he is making you float with joy through the vast ocean of biological mysteries!
Exactly what i was thinking about sir!
Simply brilliant. We need more lecturers like Eric.
A great lecture, energetic, compassionate, teaches with zeal, he obviously loves his job. THANK YOU SIR!
czcams.com/video/7eSSaiuTFBQ/video.html
I LOVE how this professor lectures in a way where one topic smoothly leads into another. I absolutely hated how my professor would teach two topics separately without showing how the two processes interact.. it confused me so much and I had a hard time understanding how all these enzymes work together in a system. I LOVED this lecture, I'm confident in my understanding of DNA replication now. THANK YOU SO MUCH.
I have to get suggestion that which book for zoology is best. For BS (undergraduate)first year .?
I am angry with Professor Lander. I almost missed a meeting because I was so interested in his talk. Excellent.
God...I'd love to have this guy as my professor
Chalk and a blackboard? Old school! I like this guy, makes it very interesting. Good video.
That is how it should be in the first place
Is this video from the 90's?
@@masacatior probably
The ONLY way you learn something from your teacher is blackboard and chuck.
He teaches so well... in such an easy manner... I'm in total awe with his teaching method... I'm a student preparing for Medical entrance exam in India & I was able to understand everything he said....
He just made me realize choosing pure line biology in your grad is totally worth!!
After a whoooole day of studying DNA, and not getting quite right, I just leard and understood it in 30 minutes! All genetic teachers should learn how be real professors.This man is gold!
Seriously the best explanation I've seen so far. The Prof really explained everything, why is synthesis 5' to 3' , how proof reading is done, how old and new strands are differentiated, literally EVERYTHING.
How exquisitely natural phenomenas are designed , with excellent proficiency and least uncertainty .
His Energy is unmatched "The Professor"
In India we have this in High School ..but no one taught us this good..especially the Proof Reading part...It really cleared my concept !!
Ekdum sahi bola bhai...The whole system here is so decadent and people who try something different are virtually non existent.
Arindam Chowdhury yet another Indian high school student here!!
SO true. We re just force-fed these things and neither teachers nor students care to understand the background of it. It's a shame.
Exactly!!!
We shouldnot blame Every the indian teachers for this ..
Watched this 5 YEARS AGO .... STILL NO OTHER LECTURE IS BETTER THAN THIS ON ENTIRE CZcams . this man is the legend .
RESPECT .
I love the way he gets excited at 7:00 with the phosphates hahah. But on a serious note, he's a really good theacher, one of the best teacher I've ever seen indeed. It's obvious that he loves his job.
czcams.com/channels/JwtSCzsltIjEHMmPNDJuHg.html
This guy is incredible! His passion for teaching literally radiates out through the screen. The way he teaches and the transition from one topic to another just makes so much sense! Way better than the crappy powerpoint presentations that are in trend these days!
You are a gift to this world, you teach with such compassion may you live forever!
Holy shyet. I already did my fundamental of biology, and general microbiology. But today is the day I finally understand what Topoisomer (I know isomer but idk what topo means).
this is awesome. I should've watched MIT's videos a long long time ago. Amazing lecture!
czcams.com/video/egpB9anFsvo/video.html
My god, the confidence he has in this lesson makes my biotech major body tremble
I love this man without getting to know him. He is 62 now; what a legend.
Why am I watching this? I am in my third semester of Biotechnology and already know all this but This great professr got me hooked
Which country you from?
i think he gives the class by emotions, and any definition he teaches, is an emotion he feels. so therefore why he is good, cause he likes to teach.
In case you didn't know, this guy was a mathematician before becoming a geneticist and, notably, was a medalist in international mathematical olympiad as a kid. I don't know if this is something he carries from his maths background, or if this course is structured this way because it's not strictly intended for biology majors, but he teaches biology in a very, kind of, logical way, which makes this stuff all the more interesting and memorable.
Its crazy how much changed in 8 years. We know so much more about replication/repair now
Exactly, I wondered why he talks so revolutionary - like.
There's an enzyme for that.
The professor has excellent academic delivery. Without PowerPoint, he put his heart and soul into the lesson. He excellent educator who has comprehensive knowledge of DNA replication.
I don't have words for his teaching, once he taught, that content can be remembered for months easily.
Nowadays teachers just showing slides and reading paper, this is real teaching, as a biotechnology student i really wish i get teachers like him,
An amazing lesson. I wonder more about DNA and the enzymes. Everytime he says "All right!" I came back from my amazed deep thoughts.
I'm still in high school and this was very interesting and helpful! I really want to study biology!
that's so good. I study biology. Biology is wonderful!!! Where do you from?
Europe! I'm in my final year of high school and I'll probably be studying Biochemistry next year!
A Noli hey I’m just wondering are you studying biochemistry now?
@@microhoarray Nope, third year Med student now
A Noli wow good for you:)
12:37 His excitement boosts my will to learn :)
Loved the lecture!! He makes molecular biology so interesting!! :D
As if molecular biology needed ANYTHING to be interesting. It is already the most amazing part of science
@@antibuergerlich3283 and biochemistry😉Well molecular biology and biochemsitry are very alike ofcourse.They are basically the same subject!
@@karkinosapoepafi8357 yeah but biochemistry is for me personally a bit to much chemistry. I prefer my molecules drawn as blobs over them drawn in chemical structural formular
@@antibuergerlich3283 That's great.I personally like chemistry more,especially organic chemistry.And that's why i prefer biochemistry over molecular biology.For me molecular biology is more difficult for some reason(than biochemistry) .Both of them are amazing subjects.All these fields are close to each other ofcourse.
@@karkinosapoepafi8357 yes and I'm so hyped to start university in 2 weeks.
For not having this teacher and not going to this school, you are an amazing teacher. Very inspiring and helpful.
Thank you!
Just amazing. Such a beautiful presentation 🌟
Acchya bhaiya Ye se padhte Ho xd
I'm blown away by this mans teaching style. I always assumed professors at the university level were not as attentive or worried about making the class interesting, but here I am, sitting through the whole video entranced about the subject. This does not comapre to the education I'm receiving at a community college.
Much better than my genetics professor. He literally skims through the content in class and uses the text book as a crutch. Sorry, but I don't pay tuition to just read a book.
Kevin Jacobson you pay for the degree. That’s the sad reality of the education today.
This is great. I love his energy and I hope the world can mirror this energy and pass it on.
It was uploaded 8 years ago n we are taking benefits from it till now
Absolutely amazing lecture. I hope to find more professors like this around the world. We need them.
One of the best lectures! This is how it should be. It shouldn't sound boring. It should be engaging and with personality such as this one.
Dr.Lander you are the most inspiring personality for me as a scientist,as a teacher...I envy the students who got the opportunity to take course from you and I must say this is a very nice initiative by MIT to post these lectures in youtube..This is a good model to be followed how lucidly these phenomenon can be taught.Regards.
What an incredible lecturer. Lots of energy.
Thank you Dr. Lander. I'm finally understanding (and LOVING) genetics.
A great teacher!
Can't help watching his classes again and again!
This lecture alone inspires me to study biochemistry at University. What a wonderful professor he is.
Good luck!
This information is great and also good to know if you're in a lab that does plasmid cloning and PCR. Especially if you need to troubleshoot a reaction.
This is the best explanation that I have ever seen about the replication of DNA. I wish that I could have this professor at my university. He has the beast didactic in genetic's teaching.
OMG this is the best professor I have ever seen in my life!!!!
The best thing on youtube is your lecture Dr. Eric lander
Thankyou so much sir, From all the fellow students of India it was a true honor to listen to this lecture.
Amazing teaching style. At some points, I forgot this was work and just got sucked into it. Truly amazing.
He is pointing out the most basic and important things... He makes it interesting.. I like his way of teaching.
This is called real teaching methodology... legend teacher
Aula incrível. Estou fascinado! Agradeço a disponibilização destas aulas no CZcams, estou acompanhando aqui do Brasil.
these videos have become so helpful since the viral pandemic of COVID-19, our Uni is struggling to provide essential online courses and as a med student I've been looking everywhere for some decent notes. Erik Lander is a legend!
Very clear explanation. Thanks, Professor Lander !
thank you MIT for sharing this incredible knowledge.. this is why we learn to share our knowledge and benefit each other in our incredible world ❤️ you can seek knowledge every were
This man Dr. Lander is outstanding, excellent teacher.
He obviously knows this so well - it's a a pleasure to follow.
Thanks Dr. Lander! I loved your videos so much I watched them multiple times. This is really helping. Very clear visuals and clear handwriting. I appreciate your enthusiasm.
A nucleoside triphosphate + H2O
ightleftharpoons a nucleotide + diphosphate
Thus, the two substrates of this enzyme are nucleoside triphosphate and H2O, whereas its two products are nucleotide and diphosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is nucleoside-triphosphate diphosphohydrolase. This enzyme is also called nucleoside-triphosphate pyrophosphatase. This enzyme participates in purine metabolism and pyrimidine metabolism.
For example, enzyme deoxyribonucleoside triphosphate pyrophosphatase, encoded by YJR069C in S. cerevisiae and exhibiting (d)ITPase and (d)XTPase activities, hydrolyses ITP, dITP, XTP and dXTP releasing pyrophosphate and IMP, dIMP, XMP and dXMP, respectively....... or something like that 😁😁😁
Eric Lander...you are a great teacher....!
I wish my university had professors such as this, thank you!!
Loved the energy and enthusiasm to make learn his students
his techniques are good to draw the attention of the students. i appreciate his tactics to make the lecture intrestings
Studying in 12th .Came for Avoiding confusion among enzymes. But learnt much more❗🧬
this professor is brilliant
I have no idea what's going on, but I love how this guy teaches with so much soul
Hahaha
He has a gift of teaching. I enjoyed myself and felt so inspired by this lecture !
Brilliant!! I just simply adore u'r teaching SIR...
DNA replication explained by one of the greatest scientist
truly amazing the way he teaches very simple.
He is great at teaching ..I'm here since My College AP is not so great at teaching since Covid is an obstacle..but I seem to bump to this ...I really like it and I seem to actually replay a bunch of times because he explain every piece of biology real good and even he get out more information why, how, when, this and more.Good Job.
My favorite bio lecturer by far!! Professor Lander is amazing, you can tell he loves his job! :)
I love seeing good teachers teach. It’s a beautiful thing!!
an extraordinary course. Thank you very much!!!!!
Ok that's the best University teacher I have ever seen.
This lecture videos still relevant till this day
Such a freaking legend!! Thank you, Sir! 👌
Absolutely well done and definitely keep it up!!! 👍👍👍👍👍
I live in Spain and my teacher did not explain this, I don't even know how I passed the exam 2 months ago and now I found this incredible professor explaining it in English and I understand it:/
This guy just made me curious about this subject. Very good professor.
He is my genetics savor 🙏🏽
He is really very energetic professor😮😮
Its looks like he is teaching from Watson 😅
you are powerful..............teacher,
god bless you
I heard the lecture and I found it very intriguing. The enzymes are the proteins in your body that break down food particles, build muscle and destroying toxins. He also brought up Arthur Kornberg, an American biochemist that discovered DNA in 1959. If there's an abnormality in your DNA, you'll get a DNA related disease. Like Cystic Fibrosis. Thank you for the lecture.
When a student answer 'half a helix' and he goes with that, I knew I am going to like this lecture.
I find watching a CZcams animation on DNA is much easier to learn than getting a lecture
This guy is an incredible person
This lecture brought my curiousity back. Thank you professor!!!