It has been a MAJOR struggle to find accurate videos explaining this! You did a very nice job. You videos were enough for me to solidify my understand of this process! Thank you so very much!
Seriously, thank you so much for taking the time to make these fantastic videos. You are helping me tremendously on my endeavor pursuing the understanding of biochemistry. Keep up the great work, I hope somebody is paying you well
+tarac9 Hey! The link is in the description. You can donate on my website! Many thanks! But I think you already found it, so thank you !! Greatly appreciate it!
Sometimes during the lecture, you say " Only protein complex 2, (while pointing on 1) and 3 and 4 act as proton pumps" around 8:09. Maybe you can put some signs there to correct it. Otherwise, great lecture!
Thank you very much for your time! Im not good with my English but your speaking is absolutely clear!! I checked a lot of videos but yours is detaled, accurate, and teaching - your explanation is fantastic!
Sometimes you wonder why things have to be so complicated. Like, 4 complexes, really?? But thank you!! Super methodically detailed and clear! The best help I've found so far in my studies :)
8:07 I believe you misspoke PC II when you meant to say PC I. Thank you so much for your great videos! Keep up the amazing and helpful content!! :) Your videos helped me through undergrad, and now I'm using them to review concepts in dental school! You're a life saver!
I really enjoyed the video doctor and studying the electron transport chain , it would be harder to understand without your perfect way , but pardon me Professor , I have a question , you said that CoQ is reduced to CoQH2 ,I don’t understand that point , complex I is supposed to be a proton pump , so where did it get the 2 H ions to be reduced , and of course it’s not going to be in it’s reduced form forever ,so how the CoQ will get rid of the 2H ions ?,
Such a great lecture sir. I am preparing for my competitive exams with your lectures only. My request, can you pls upload lectures on BIOINFORMATICS topics?
oh my God l cant believe this topic is easy ,my lecturer just complicated it ,could you please come and teach in our university....lol.....l enjoyed the video
But your lecture is silent on what is the form of energy relesead during electron movement through complexes. And how is it responsible for the movement of proton from inner membrane to outer membrane????
Great presentation of the material! May I ask what technologies you are using to create this? I am an educator as well and love how you are incorporating technology like this with the presentation of your material. Thanks for any information you can provide.
Can you explain to me how 4 H+ (protons) are pumped out of NADH dehydrogenase (complex 1) PER NADH MOLECULE? Im confused because NADH --> NAD+ + H+ + 2e- Where am I going wrong? This is driving me nuts!
Like so many profesional science lecturers, you have someone who understands the subject really well, puting it out to people who don't, like trying to get them to drink from a firehose! Suggestion. Slow the H down!! FYI, I used to teach.
Hey maaaaan, I get the first .5 q cycle and i get the second .5 q cycle , but how is the Ubiquinol regenerated within complex three after its release in the second half of the cycle ??..Because It goes into the inter membrane space as a fully reduced molecule . If you take another spin through the q cycle it will be lacking the ubiquinone , no?
Hi Can I ask how many ATP molecules are produced in every ETC complex? It was actually raised by our professor, according to him, every complex in the electron transport chain produces a particular amount of ATP.. He wants us to identify the ATP molecules produced in: Complex I Complex II Complex III Complex IV. Thank you so much for those who can help☺️
At complex 1,ATP is produced Complex 2 ,1 ATP is produced At complex 3 ,1ATP is produced And no ATP is produced in complex 4 because here water is produced
10:00 Pretty sure it's called oxidative phosphorylation because the electron carriers lose electrons through sequence to generate ATP - not because complex IV uses oxygen.
LiNingAir Electron carriers in light reaction also lose electrons to pump protons and ultimately generate A.T.P. But instead of oxidative, it is called photophosphorylation. So he may be right about the oxygen thing.
Shafiul Alam Plus if you look at the structure, its not a transmembrane protein. It simply doesn’t have access to the other side of the membrane, thus not being able to pump the protons.
FAD is part of the complex; that is, it is attached to it and merely acts as a conduit for electron flow. During the Krebs cycle, FADH2 is formed, yes. But when it is formed, it is quickly converted back to FAD, releasing the H ions along with the electrons. These electrons move through Fe-S clusters and ultimately onto the electron carrier in the membrane.
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Life hacks for Med students;
Nr 1; AK Lectures!
Thank you, Andrey!!!!!
+Nina Sulemani Thanks for watching Nina! :)
I'm studying dietetics, and I'm signing this as well! :)
It has been a MAJOR struggle to find accurate videos explaining this! You did a very nice job. You videos were enough for me to solidify my understand of this process! Thank you so very much!
No one does it better. AK youre the best.
You are better than my professor
I honestly cant thank you enough for all your videos, you've made my life as a pre-med and soon to take the mcat much more bearable haha
Seriously, thank you so much for taking the time to make these fantastic videos. You are helping me tremendously on my endeavor pursuing the understanding of biochemistry. Keep up the great work, I hope somebody is paying you well
Thank you so much! These videos are a life-saver. Everyone should donate so we can keep this going!
+tarac9 Hey! The link is in the description. You can donate on my website! Many thanks! But I think you already found it, so thank you !! Greatly appreciate it!
Your videos helped me through pharmacy school. I’m most grateful
Sometimes during the lecture, you say " Only protein complex 2, (while pointing on 1) and 3 and 4 act as proton pumps" around 8:09. Maybe you can put some signs there to correct it. Otherwise, great lecture!
omg this video helps me to understand how ETC works, I've been watching so many videos and this one explains it clearly and detailed. Thank youu!!!
Thank you very much for your time! Im not good with my English but your speaking is absolutely clear!! I checked a lot of videos but yours is detaled, accurate, and teaching - your explanation is fantastic!
You're so useful for my science assignments. thank you for your great videos I been using for over 2 years.
Sometimes you wonder why things have to be so complicated. Like, 4 complexes, really?? But thank you!! Super methodically detailed and clear! The best help I've found so far in my studies :)
saddlepotato159 it's not abig deal
I love your lectures!!! so helpful for biochemistry!
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I passed my first biochemistry colloquium because of your lectures !!! Will donate
this is amazing! oxidative phosphorylation in a nutshell. this is for sure has been super helpful thank you for the effort put into this!!!
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Thank you. You have no idea how much you save me daily.
8:07 I believe you misspoke PC II when you meant to say PC I. Thank you so much for your great videos! Keep up the amazing and helpful content!! :) Your videos helped me through undergrad, and now I'm using them to review concepts in dental school! You're a life saver!
I figure since we all caught it and new exactly what he meant to say, it isn't so important to fix it.
@@ElanaSl This is true, just wanted to leave it here for anyone who might actually be confused. :)
Thank you so much for your great videos :) ! The way you structure and present the subjects makes it so easy to follow and learn the material :)
Cygne Gris you're welcome! Thats awesome to hear! :)
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Binge watching AK LECTURES like " House of Cards", Andrey is also starting to look like Spacey :). Internally grateful, thank you!
It'd be pretty amazing if your lectures tracked my medical school topics
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I love your way of teaching thank u you save my live
I really enjoyed the video doctor and studying the electron transport chain , it would be harder to understand without your perfect way , but pardon me Professor , I have a question , you said that CoQ is reduced to CoQH2 ,I don’t understand that point , complex I is supposed to be a proton pump , so where did it get the 2 H ions to be reduced , and of course it’s not going to be in it’s reduced form forever ,so how the CoQ will get rid of the 2H ions ?,
Thank you so much, your lectures are incredible!
Such a great lecture sir. I am preparing for my competitive exams with your lectures only.
My request, can you pls upload lectures on BIOINFORMATICS topics?
Andrew, you are the BEST!!!
oh my God l cant believe this topic is easy ,my lecturer just complicated it ,could you please come and teach in our university....lol.....l enjoyed the video
But your lecture is silent on what is the form of energy relesead during electron movement through complexes. And how is it responsible for the movement of proton from inner membrane to outer membrane????
Great video and awesome explanation, thanks a lot man for all videos.
Great presentation of the material! May I ask what technologies you are using to create this? I am an educator as well and love how you are incorporating technology like this with the presentation of your material. Thanks for any information you can provide.
U r just amazing in ur lectures
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You're a legend.
Can you explain to me how 4 H+ (protons) are pumped out of NADH dehydrogenase (complex 1) PER NADH MOLECULE? Im confused because NADH --> NAD+ + H+ + 2e- Where am I going wrong? This is driving me nuts!
Amazing content!
Thank you so much! :)) This helped me a lot
Like so many profesional science lecturers, you have someone who understands the subject really well, puting it out to people who don't, like trying to get them to drink from a firehose! Suggestion. Slow the H down!! FYI, I used to teach.
Thnx for the superb lecture
thakn you Mr. AK lectures
Raheleh Majd czcams.com/video/k0ayiFBxhZs/video.html
Why etc should happen in stepwise manner .. I mean why complexes are...??? please ans
thank u so so so much..very informative and helpful😘
Hey maaaaan, I get the first .5 q cycle and i get the second .5 q cycle , but how is the Ubiquinol regenerated within complex three after its release in the second half of the cycle ??..Because It goes into the inter membrane space as a fully reduced molecule .
If you take another spin through the q cycle it will be lacking the ubiquinone , no?
thanks for these details
Hi
Can I ask how many ATP molecules are produced in every ETC complex?
It was actually raised by our professor, according to him, every complex in the electron transport chain produces a particular amount of ATP..
He wants us to identify the ATP molecules produced in:
Complex I
Complex II
Complex III
Complex IV.
Thank you so much for those who can help☺️
At complex 1,ATP is produced
Complex 2 ,1 ATP is produced
At complex 3 ,1ATP is produced
And no ATP is produced in complex 4 because here water is produced
10:00 Pretty sure it's called oxidative phosphorylation because the electron carriers lose electrons through sequence to generate ATP - not because complex IV uses oxygen.
LiNingAir Electron carriers in light reaction also lose electrons to pump protons and ultimately generate A.T.P. But instead of oxidative, it is called photophosphorylation. So he may be right about the oxygen thing.
are the complex 3 and 4 names interchangeable? my textbook has complex 3 as complex 4 and vice versa
hello. please what is the difference between electron transport chain in eukaryotic and prokaryotic cells.
Great you!😊
You are awesome sir
You're GREAT!
How is complex II called succinate reductase?
GREAT!!!!!! As usual
Great
Does superposition play any role in this process?
youre realllyyyyy cool. you help me a lot : ))
Are these complexes also known as integral proteins?
Thank you soo much. It is just awesome :)
Is there any way that we could pay you, seriously you are saving us so much time
read the description
Thank you so much
How can we donate ?
No explanation on why protein complex 2 can't pump protons. would be jubilant to get the answer
because it's not a proton pump? It's just an enzyme
Shafiul Alam Plus if you look at the structure, its not a transmembrane protein. It simply doesn’t have access to the other side of the membrane, thus not being able to pump the protons.
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nyc lecture
good strucutre
on point!!!
I thought the substrate for complex II is FAD, and the product is FADH2.
Confused by this too.
FAD is part of the complex; that is, it is attached to it and merely acts as a conduit for electron flow. During the Krebs cycle, FADH2 is formed, yes. But when it is formed, it is quickly converted back to FAD, releasing the H ions along with the electrons. These electrons move through Fe-S clusters and ultimately onto the electron carrier in the membrane.
I am in love with you. if I make to medical school it will be because of you