Steps of glycolysis | Cellular respiration | Biology | Khan Academy
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- čas přidán 24. 08. 2015
- Introduction to glycolysis. Role of glycolysis in producing ATPs and NADHs and converting glucose to pyruvates.
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Why do I feel like the more science you know, the more you realize the less you know.
It's a bit like if you inflate a balloon, the volume represents your knowledge, the surface area represents the things your discover that you don't know. I guess it's just that you first have to understand the basic concepts of something to realize how much there is to know about it and until you do, all of that doesn't exist to you.
Kant has a theory about this. the more you know you are pushing your knowledge limitations further and you realize how little it represents.
hahaha! same man!
"As for me, all I know is that I know nothing" Socrates used to say. Humans are always the same:)
That means your learning and your way of thinking has been advised by several of my professors
‘mind wanders for 5 seconds’ welp time to go back 3 minutes
facts
That’s so true
so true!
story of my life
Seriously smh
Cool. Now if I watch this 10 more times I might have it memorized. . . Maybe.
Write it down from memory instead - much more efficient
Wow so fast?! (not even ironic)
literally same
@@onetwoBias I agree!
Maybe checkout a less detailed one? It's rly not tht complicated
Thank you for making FREE videos for PREMED students. Many intelligent students can't afford MCAT prep packages and even basic books! So you are doing a huge favor to them by making detailed videos on MCAT topics. All of the poor students are future doctors and they will be donating regularly to this amazing channel ❤ I wish a free medical school will be established one day just like Khan Academy, professional, kind and generous, in which people can study doctor of medicine for free.✨
Kahn puts my $100 biology textbook to shame. He's straight up out here slaying the science game. Thanks, Kahn.
Atleast spell his name right...
@@mohamedmotaz5194 he clearly khant
If my body was able to take my biology test for me, I would've totally aced it.
Stop sounding so excited, we hate glycolysis.
Lmao true
ahhahahahahaha This one takes the cake
Nah, I enjoy learning about it, it's interesting to know what's going on in our bodies
WaveDancer171 you do...And that's great! This is just the silly opinion of 90 percent of the people studying glycolysis..😑
WaveDancer171 you will hate it once you will see this in order to memorize it.
Even if this man was speaking in Navajo, my current level of understanding would still be the same.
Aquarian Sage retweet
that is literally me 2 years later. funniest thing i read all day..
🤣🤣
you know it that well?
I have to memorize this for Tuesday. Lord help me.
May God help you.
how did u do?
shko ata well I had Glycolysis down, but the rest of the exam was the beggining of my demise
i need to learn al of this for this tuesday ha. Apparently tuesday is test day
Aimee I have to memorize this for tomorrow...
3:13 is aCtUaLLy litEraLly the epitome of expectation vs reality and I died
best comment
i cant stop laughing !!!
😭so tough for a class 10 student like me
I will always love biology the most. Chemistry, well, not so much. I mean it's quite an interesting subject but it makes me struggle so much at school. Same for Physics.
Weeeell, we have this topic for biology and I now only understand it more in Khan Academy than my Bio teacher.
@@anshikasrivastava3951 Being indian has absolutely nothing to do with that
Great video, however one simple mistake:
Kinases don't "dephosphorylate" molecules under physiological conditions. Enzymes for dephosphorylation reactions are called "phosphatases".
The reason why the "pyruvate kinase" is called kinase is that while these metabolic reactions were being discovered, scientists tried out these reactions in vitro to see what the enzymes do and they put too much pyruvate and so turned the reaction balance in favour of phospoenolpyruvate (PEP) as product, so they thought, the enzyme phosphorylated pyruvate.
But in reality, under physiological concentrations, the enzyme actually "dephosphorylates" PEP.
Thank you for this nice information 👍 It can be crucial detail.
I can's appreciate the complexity when I need to know all of this for a test lol
I look away for 20 seconds and next thing you know, I'm as lost as a 3 year old in walmart by how much stuff you just put on the screen
Sigh, that's biology for you
Gosh this guys you'll be a voice actor; he's got such a soothing and calming voice ^_^
Sloth no offence but to me he sounded really excited which was kind of annoying since I was breaking my brainpan to try make sense out of glycolysis....
90% of the video: we talked about this in another video
10% of the video: actually explaining glycolysis
Wish the number of your comment's likes add to your IQ
This man knows everything, only rival to Johnny Sins himself.
Why is life so complicated!?
Creativity of god
Yet another equation : law_of_physics x random x huge_amount_of_time x selection = complexity of life
Cuz complexity makes life awesome
the double meaning...👍
Coz we r science students✌
You really made it so much easier to understand. Thank you!
Dope video, I love how you actually enjoy what you're talking about and are enthusiastic about it!
Thanks SO much, for all the videos you provide... It's helped me a lot throughout my medical career in the Dominican Republic. I finished it, and will graduate soon. Right now, I'm studying for the USMLE and reviewing quite a bunch of knowledge gaps!
I don't agree with the comments on how his speech is too excited or whatever. Precisely, that's what makes me NOT fall asleep or get bored, since the way he talks makes everything much more interesting.
i studied glycolysis for nearly 4 years and only that video makes me understand it
hey, Mr. khan, Id really appreciate it if you could include printable versions of the notes that you write in the videos as a link in the video description.
You just made me understand the cycle in 12 mins that my teacher couldn’t in a 2 hours lecture. Thank you so much for putting this out for FREE
I always watch your videos if I need to study something or I need to teach it’s so well explained!
THIS IS THE BEST VIDEO ON GLYCOLYSIS EVER! Please do one like this on kreb cycle please!!!
This video helps me a lot to understand the glycolysis process. Thanks!
Thank you so much. A wonderful review for SAT subject test for which I am preparing even though College Board requires me to know much less about Glycolysis than what this video taught me.
me: finished the video
Also me: and that's why i hate sugar.
“this over here was replaced with that over there”
Had to memorize all the anabolic and catabolic processes for my upcoming test next week. Please bless my soul.
Great video, thanks for mentioning all the enzymes involved
thank you so much for this vid! helped me so much! my biochem professor is clearly failing at explaining
Thanks a bunch mate. That is exactly what I needed.
thanks to this academy, my grades aren't dropping like hell. love this channel
Amazing video. Very very helpful! Thank you Khan Academy!
my teacher explained this in a way that is hard to understand, and i am soooo happy this channel exist
This is GREAT!!! Thank you!
MCAT is in one month. This is a life saver. Thank you!
howd u do
@@emeka3033 92 percentile! Thank you again!
@@davidadams255 you legend, I’m studying for my first test in mid august
@@emeka3033 best of luck my friend...make sure you work hard and make every moment of studying count. Perhaps even more important, make sure you give yourself time every week to rest and reward yourself for your hard work. Best of luck to you
wow! BRILLIANT!,I am from Ethiopia East Africa and I love learning from your video!
This helped me so much, thank you.
This is really appreciated. This one is the best one 😍
It only took him 6 years to post the video. lol
This is what I need for the exam next week 😌😌 Thanks God you are here Khan
Thank you very much you make my life easier !
Really helpful.. Thanks alot and much appreciated
The best! Thank you so much!!
You just explained what my biochem professor has been trying to explain for the past 2 weeks. (and drastically failing at it) Thanks!!
DannyAwesome63 A professor had to explain this in bio chem?! Wow I am learning this in general biology. Makes me less afraid of biochemistry now!
I had to walk out of my biology lecture and just look this process up on Kahn Academy because there was no way I was going to absorb any information with the way she was teaching it.
@@Autumnpaige19 Biochem, you learn the mechanisms and reproduce them.
I real appreciate this video. Helps too much
Wow... I just began bio 20 and I’m already hooked on this, but I really should’ve taken Chem first!
itd be nice to have the whole page in one shot, so i could follow the reaction process
Omg thank you so much this really helped me for my freshman bio class
great video, glad to know i can always come here for science help! :D
Thank you that was very helpful for me 🙏❤
just for the record, the two kinase enzymes in steps 1 and 2 transfer a phosphoryl group, NOT a phosphate. It seems like splitting hairs, but it's important to account for the oxygen atom.
that was great! thank you sm
Thnxs this is very helpful of my study
thanks a lot... u helped a lot
"3 cahhh bunn molecule" at 0:26
couldn't stop laughing at that part lol
majestirial,world class,sensational,brilliant,astonishing,intimate,definitive,point-wise.......
so much effort..😄 god bless u
Is there a video of cellular respiration using fructose or sucrose? I need to know it and can't find a video anywhere! Please help
Last 2 seconds of the video:
"Actually makes sense"
(JAW DROPS)👍
In what Universe would anyone consider disliking this video. Thanks you 🙏🏻
Superb explanation 👌👌👌🙏🙏🙏
I love you man come and teach in my University,:")
Hi there, during the cleavage phase, what molecule or enzyme splits the p-c3-p into the G-3-p?
literally helped me SOOOOO******* MUCH thank you Khan!!!!!!!!!!!!!!!
I love you thank you for everything you do.
thank you for a really nice presentation! Like your drawings and your voice ;)
THANK YOU!!!!
I learned this at the start of my school year. Forgot it by the end
Khan academy is a life saver
Haha, gotta love the excitement :D Thank you
thankyou so much
Awesome👍
thank you
Can some one please explain where the second phosphate group that was attached on the glyceraldehyde came from
just know that whenever there is formation of ch2oh in glycolysis, the h gets replaced by a phosphate group
@@FavouredElm2 thank you so much I really appreciate it
@@goshakrasovskiy7072 no problem
Ur talking style and ur voice make me listen u again and again.. 😅😍
Great video👍
Lmao your voice literally made me excited when reaching the end😂 anyways, I always understand anything through your videos. Love em❤️
after the phosphoglycerate mutase step where does the hydrogen on the bottom of the next step come from?
I have a quick question, which software one could use for online blackboard, like this video used?
Borrowing your brain to take the exams sounds better than this lol
i thought i was the only one who thought like that
Shani Williams I know right!!!
Lol bet they graduated by now
Triosephosphate isomerase (TPI) is a perfect enzyme that catalyzes dihydrooxyacetone phosphate into 3-phosphoglyceric acid. There is an enol middle metabolite between these two steps. But this enol middle metabolite is easy to release phosphate group and become to malonaldehyde in a neutral cellular environment. The significance of TPI enzyme lies in that it has approximately 10 aa residues forming a loop that is designed to cover the enol middle metabolite preventing its release. In the end, as long as 3-phosphoglyceric acid is produced, this loop or cover will leave and let 3-phosphoglyceric acid go and do next reaction into 1,3- diphosphoglyceric acid.
What about the Triose Phosphate isomerase that keeps both molecules (after alodase catalyzes fructose to basically split in half) as Glyceraldehyde (wanted 1st isomer) and not Dihydroxyacetone Phosphate (unwanted 2nd isomer)?
finally I've understsnd
I think it’s cruel that the A.P. Bio, 12u bio curriculum requires us to memorize the steps of glycolysis. Although, I do appreciate the complex process that allows us to break down sugar from food and convert into the universal energy currency, ATP.
thank you for the vidya, you got a fire voice
Now glycolysis sat in my mind😍
In my chemistry book and other sources there is one hydrogen less on the final pyruvate molecule. You have a full COOH group there, which one is correct ? Pyruvate with COO- or COOH ?
Thanks. My text book had a description that didn't match it's diagrams. Why can't there be at least one text book in this world without errors?
İ want to ask when there are two molecules of pgal each attached to a phosphate group how do they get the other two phosphate groups if they dont use 2 more atps!?
You should do all the videos man,
So where does the 3rd mentioned phosphate come from? (glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate)
u are a genius sir
teacher moved test to tmrw. panicking. no time. bye
How’d it go
The people demand answers
Hi there,
In the graph you drew, you only have 5 hydrogens for glyceraldehyde 3 phosphate. However, the formulate for this molecule is C3H7O6P. Just a little confused with why there are 2 missing hydrogen.
Thank you so much
the phosphate is with or withour hydrogen atoms, since it reacts with water in an equilibrium reaction. He chose to draw it without the hydrogen; yet, we can still put the phosphate with the ti hydroxyles
i find everything about this so simple
thxx sooo muchhh!!