Vaccine design against infectious agents | 4th International conference on Bioinformatics | Lec 150

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  • čas přidán 9. 09. 2024
  • The 4th International Conference on Emerging Trends in Bioinformatics and Biosciences (ICETBB-2022) was held at Hazara University, on SEPTEMBER 15-17 2022. It will be organized by the Department of Bioinformatics, Hazara University, Mansehra, KP, Pakistan.
    The Conference is to be held every year and is the Third in the series. Its scope covers new and exciting research areas, thereby inviting the interest of a large audience. The conference targets research presentations by academic and professional researchers and also includes invited talks enabling participants to learn about the latest trends in the field of Bioinformatics and Biosciences.
    The Fourth International Conference on Emerging Trends in Bioinformatics and Biosciences provides opportunities for the delegates to exchange new ideas and application experiences face to face, establish business or research relations and find global partners for future collaboration. It will also help to identify and discuss strategic and technical options that may have been proposed by individuals to promote and encourage Research in the field of Bioinformatics in specific and Biosciences in general.
    Gaps and key issues will be identified that need to be addressed in relation to the focused R&D and training of manpower for academia and industry. It will help to engage, train, and boost the young scientists of the country in the relevant fields, in particular with regard to the concept called “Research Applied to the National Needs”.
    Research contributions are expected from the participants, covering various disciplines under the domain of Bioinformatics and Biosciences. For all submitted papers, the review criteria include the significance of the problem, novelty, clarity, completeness, and accuracy.
    IMMUNOINFORMATICS AND REVERSE VACCINOLOGY-BASED NOVEL VACCINES DESIGNED AGAINST EMERGING, RE-EMERGING, AND MUTI-DRUG RESISTANT PATHOGENS INFERRING VARIOUS INFECTIOUS DISEASES
    Vaccine design is the most essential and intensive phase of the entire vaccine development process. The field of immunoinformatic focuses on using computational arrangements to study the immune response of a host against the pathogen. Reverse vaccination employs each pathogen's entire protein repertoire to pick the best potential vaccine antigens. This enables the creation of vaccinations that were previously challenging or impossible to produce and may result in the identification of novel antigens that could enhance currently available vaccines. Reverse vaccinology principles and immunoinformatic have recently merged to create and assess novel vaccines in silico, providing an effective response to emerging infections. This study describes the computational vaccine design constructs against some emerging, re-emerging, and multi-drug resistant infectious diseases caused by Human Parainfluenza Virus, Enterobacter cloacae, SARS-CoV-2, Serratia marcescens, COVID-19-Associated Mucormycosis and Klebsiella pneumonia by detecting and predicting the critical elements of the vaccine, such as B and T epitope, the appropriate linker along with an adjuvant to make an effective subunit vaccination. The various epitopes were chosen, according to their allergenicity, antigenicity, and toxicity scores. The constructed vaccine models were docked with multiple immune receptors and cloned using snapgene, for expression analysis. Immune simulations were carried out by the C-ImmSim Server to examine the immune system's response to the constructed vaccine model. Therefore, the immunoinformatic approach leading to reverse vaccinology facilitates anticipating the vaccine construct's features quickly and saves the researcher's time for additional experimental investigation.
    About Dr. Muhammad Naveed
    (Associate Professor, Biotechnology, University of Central Punjab, Lahore)
    With distinction, Dr. Muhammad Naveed obtained a Ph.D. degree in Biotechnology (Genomics & Bioinformatics) from Quaid-e-Azam University, Islamabad. He has won Ph.D. indigenous & IRSIP scholarships from HEC. He has done Pre-Doc research at the University of Ghent, Belgium. HEC awarded him the best Ph.D. (IRSIP) Scholar of the year in 2013 & QAU honored him as “Distinguished Alumni” in 2017. He is doing research projects in Bioinformatics, Molecular Biotechnology & Vaccine designing, and Drug designing against infectious diseases. He has supervised 70 MSc. and 60 MPhil. & 01 Ph.D. students. He has published 102 Research articles with 504 impact factors, 1650 citations, 01 book, and 03 book chapters. He has been awarded the distinguished “Researcher of the Years” 2016 (UoG) and 2018, 2019 & 2021 (UCP).
    #bioinformatics #vaccines #conference

Komentáře • 3

  • @AliRaza-fi5wz
    @AliRaza-fi5wz Před rokem

    excellent sir g......!!

  • @ojeniyifiyinfoluwa8251
    @ojeniyifiyinfoluwa8251 Před 11 měsíci

    Hello Prof. I want to humbly request for your slides on vaccine design. Thank you very much.

  • @techinbox2
    @techinbox2 Před rokem

    AoA.Thanks for informative video.
    Sir Let me knew, i have 3.49 CGPA in MSC COMPUTER SCIENCE, AND I want to Apply Recently announced COMMONWEALTH SCHOLERSHIP 2023,
    But I Have 3rd Division In my intermidiate Let me Knew, sir Can i Eligible for this Scholership Or Not. Please Answer as soon as possible. I m waiting your Response.