Pharmacology - HEART FAILURE (MADE EASY)

👉 READY TO ACE YOUR EXAM? 📚 GET STUDY NOTES ON PATREON!
/ speedpharmacology
Heart failure is simply defined as a chronic, progressive disorder in which the heart muscle is unable to pump enough blood to meet the body's needs. Depending on the primary cause, heart failure can manifest itself as either systolic or diastolic dysfunction. In systolic heart failure the heart muscle becomes weak and cannot squeeze as much blood out. In diastolic heart failure the heart squeezes normally, but becomes stiff and cannot adequately relax to allow for normal ventricular filling. In the presence of heart failure, in order to counteract the effect of falling cardiac output and thus reduced perfusion to vital organs, the body will try to compensate via two tightly regulated mechanisms.
The first one involves the increase in sympathetic nervous system activity. The second one involves the activation of the renin-angiotensin-aldosterone system. This pharmacology lecture discusses mechanism of action of various drugs classes used in management of heart failure including beta-blockers, ACE inhibitors, angiotensin II receptor blockers (ARBs), angiotensin receptor-neprilysin inhibitors, aldosterone antagonists, loop diuretics, vasodilators, and cardiac glycosides.
Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!!
00:00 Heart & Circulatory System
01:40 Types of Heart Failure
02:50 Sympathetic activation
04:05 RAAS activation
06:40 Natriuretic peptides
08:17 Beta-blockers
09:43 ACE inhibitors
10:45 Angiotensin receptor blockers
11:48 ARB/Neprilysin inhibitor
12:56 Aldosterone antagonists
13:43 Loop diuretics
14:45 Vasodilators
16:11 Digoxin

[@subhikshakannan1573]

Thanks a lot!!! I just completed my pharmacology exam today... Without your vids Idk how would I have even survived it..... Wish I could have found this channel way before.... But anyways it helped me a lott... I am literally wordless how to thank you.... May your life be filled with all happiness and fortunes... Thanks once again

[@musicbeachdance]

Thank you for this video! You summarized 6 hours of lectures in

[@rutviktaviyad5677]

Your work deserves standing ovation

[@gregfam6250]

Such a clear explanation. If _this_ is how I was taught twenty years ago I would have really retained a whole lot more than I did, and understood twice as fast. Thank you for the revision!

[@samueloladapo4178]

Wow, I loved the way you explained from scratch in the shortest way possible. Much love ❤️

[@cynthiabrock3608]

After 20 years I am finally going for my Pharm Tech and your videos explain so much and they are amazing. Thank you for helping me... Cynthia Lantz

[@kerryjones8412]

incredible amount of information in 17 minutes here. Thanks man!

[@nitutuni4303]

Thank you so much.. Such an incredible effort to make it as clear as possible..
Hats off.

[@zannatulmaua5824]

Classes are very informative and beneficial! Thanks a lot!

[@FnLn55]

Clear and concise - thank you very much!

[@a.b8682]

Literally did the exam today 😭. Wish the video came sooner.

[@invisible_d_r]

I got a lot from your lectures thank you a lot!

[@ucakakuru2442]

I'm so grateful,your videos were of great help in enabling me understand pharmacology and passing it.Keep up the good work!

[@drankushgoyal5775]

I cannot explain how much your videos useful make all videos on pharmacology great work

[@syedmedicose7477]

MIND BLOWING LEC SIR KEEP GOING LOTS OF PRAYERS FOR U

[@Saba-nh8up]

Thank you so much for such a easy and reliable video which make our concept more stronger

[@leo861]

THIS IS SOOO GOOD! THANKS ALOT man❤️ You're indeed a life saver.

[@monalipatel2182]

thank u so much... your simplified explanation makes it so much easier to understand & retent the topic knowledge...

[@syedmansoorabbas5370]

Such a deep knowledge you have sir hats off to you and keep it up😍

[@Biomeducated]

*Another great video! Keep 'm coming!*

[@hermionegranger1861]

The best pharmacology vid ever. Thanks a lot.

[@dekimasu8959]

Wow.perfect....i was just searching for this...osmosis had little detail...thank God u came timingly

[@Syedaqeelpasha]

You’re lectures are mind blowing. Please upload more topics.. and also about the standard diet according to age
Thank you 😊

[@cm-fh1cb]

Thank you so much for this amazing video. I have been confusing and struggling for so long. You have saved me😭🙇‍♀️

[@talab703]

Absolutely life savers... thank you so much!

[@joan28117]

every time i revise i always come back to this video! LIFESAVER

[@kaquali566]

This video is just in time
Thank you🤗

[@DrpradyCl]

Amazing video, helped me to visualise things, and even small concepts behind any mechanism are covered,
Thanks a lot ❤

[@risht843]

Thank you for this!! Amazing lecture as always

[@LOOP931]

Thank you. U brilliantly summarised everything 🥺❤️

[@theresemaecasaysay7464]

thank you so much! you're a life saver

[@abdallahmohsen7036]

always like before watching for your wonderful effort ... thank u very much sir

[@juli11051]

Thank you so much! Your videos help me a lot

[@ayachb3563]

Thank you so much ❤ this was very helpful!

[@SANTOSHSINGH-uk3yw]

This channel which is created by you that out of the world .🖒🖒🖒. keep it up

[@abdulmuneeb8190]

Oh My God ...I had been waiting for it for so long .... Thank you ... Now next Anti angina please

[@adityanagar394]

Thanks lot sir I m just wanted THIS please add more on cvs like anti anginal and more 👌👌👍👍

[@misslee4245]

Finally, drug for HF 😍. I thought you forgot to put hehehe. But I understand it must be hard and time consuming to make even one videos. This is my main channel to better understand about pharmacology. Very informative videos ❤️. Been listening to most of the videos here. Maybe you can also put antianginal drug video, and all the CVS drug would be complete 🤗.
- 3rd year pharmacy student ❤️

[@SpeedPharmacology]

Thanks for watching! Yes - these videos take a lot of research, planing, designing and editing hence it takes a long time to make one

[@oseanjobvu5698]

Hey 👋

[@thedarkingman4468]

You are the most helper video in CZcams

[@reemismail777]

wow..great content. Please keep uploading more videos

[@curtisprice9806]

I just hope my stupid disregard for my heart's health didn't cause too much damage! I am in pain from fluid on my heart. It has caused me over two weeks of little, to no sleep because of panicking from a crushing feeling that occurs whenever I lay down prostrate. On the other hand, there needs to be a much, much greater understanding of the dangers that are very real to over the hill people like me (55 yrs. old). I really hope I didn't mess up my heart permanently by my "Superman" nothing can hurt me belief. I could see clearly how this heart failure video goes about trying many remedys for the heart that got injured.....very eye opening....excellent!!!!

[@celestialdemi2655]

Thank u this helped me understand my past heart failure

[@carlotavillanueva4087]

THANK YOU SO MUCH!!!

[@sueda4697]

thanks for the clear explanations

[@ProfShibe]

Thank you bro. Love these videos.

[@adityaharne1702]

Thank u for existing

[@camilamartinez9518]

This video is GOLD

[@yuvasrid2224]

Excellent! ❤

[@holeung973]

amazing video very detail and informative!!

[@natarajanmanickam5119]

Excellent teaching

[@dr.sameen]

Thankyou for the best explanation ever🎉❤

[@chrismunene5000]

Great work Sir

[@bethpot]

Perfect explanation

[@yadagirimbbs1]

Nicely explained. Thank you🙏 sir❤

[@dawoodakram123]

Great to see this types of video

[@pupsiuspupuliukas2394]

great summary

[@sumathyveeraragavan7788]

Very good lecture sir ...thanks a lot

[@hnzheng4883]

thank you！！！！！really helpful❤️

[@rutviktaviyad5677]

This video best, best, best more than anything

[@deedominus1002]

Epic content!

[@TheSiRiUs9]

Awesome explanation

[@unmpo20]

Great summary and review for my cardiac pharmacology test. Maybe in the future videos you could discuss ca 2+ channel blockers and HCN inhibitors.

[@faizanwani_]

you are the best. 🙌🏼🖤

[@user-xp4on7lz5z]

Thanks you!

[@shreeradhakrishnasiddharth5576]

Thanks sir
I was very helpful 🙏🙏🙏

[@richardwroy14]

Excellent!

[@rouaalharby2987]

Thank you so much ✨

[@ZT2023]

Very nice explanation thx very much

[@hishamalnour9072]

Thank you very much

[@maca_ker]

Just in time :D thank you

[@omkardevang8611]

Thank you so much sir 👍🏼

[@desiremangha3463]

Thank you

[@malikoun3090]

You are blessed 💕

[@MylensPerspective]

Thanks for this boss

[@user-jp1gt9ts2u]

Thanks man❤

[@sharyanazir9850]

Thank you sir.

[@awaisraza3378]

Nice lecture 👍

[@duwishur_networking]

Thanks a lot sir. we are from india. I love your videos alot. ❤

[@dr.rofikullahahmed6318]

My fav channel

[@Tulama]

thankyou u made it really simple🤙🤙🤙🤙

[@santiagoperote5887]

Gracias amigo!!

[@freshtomato7888]

great video.. thnx a lot man

[@afaatim]

SO GOOD

[@brightmukisa2178]

In Digoxin, the accumulation of Na+ in the cell instead inhibits the Na+/Ca+ pump which usually pumps out Ca+ and takes in Na+. this is how the accumulation of calcium ions occurs leading to increased contractility of cardiac muscle cells. The blockage of the na+/K+ pump is followed by blockage of na+/ca+ pump

[@ryanmark4660]

Great video 👍
What program you use to make and edit your videos ?

[@evanalijabbaroleiwi2515]

Thanks ❤❤❤

[@abdallahmohsen3406]

U are too good.. thanks alot

[@AzzaBakhit]

Thanks

[@Ak.shafi7104]

Soooo good 💯

[@dekimasu8959]

Pls explain abt diff types of arrhythmia and aneurysms..pls

[@rimonmahmud3733]

Really um waiting for that
May Allah bless you!

[@tabinda2922]

please make a video on antianginal drugs aswell

[@varshareddy-we3dv]

Topnotch explanation

[@mehakiqbal1759]

Thank yOu🌸♥️

[@carinat3365]

the Best 🙌

[@MrMIKI3m]

I don't know if someone will read this after a year, but what about SGLT2 inhibitors in case of low ejection fraction? I think they are included in the new guidelines.

[@drugbank2789]

@speedpharmacology sir what software u use for videos 📹 kindly respond me

[@rony0316]

Thank you mannn

[@satyajeetgiram3958]

Thank u

[@Ak.shafi7104]

Thanku so mch